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Biliary anastomotic leak

MedGen UID:: 96035
•Concept ID:: C0401006
•: Pathologic Function

Synonyms:	Bile leakage from biliary anastomosis; Biliary Anastomotic Leakage
SNOMED CT:	Bile leakage from biliary anastomosis (235940009); Biliary anastomotic leak (235940009)

Definition

Leakage of bile due to breakdown of a biliary anastomosis. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBiliary anastomotic leak

Pathological Conditions, Signs and Symptoms
- Clinical finding
  - Finding by Cause
    - Leakage
      - Body Fluid Leakage
        Gastrointestinal anastomotic leak
        Biliary anastomotic leak

Professional guidelines

PubMed

Biliary Leaks: Multidisciplinary Approach to Diagnosis and Treatment.

Schertz PJ, Mao CA, Derrick KD, Galar F, Ortiz CB, Walker JA, Lopera JE
Radiographics 2024 Jul;44(7):e230155. doi: 10.1148/rg.230155. PMID: 38935550

Endoscopic Management of Biliary Issues in the Liver Transplant Patient.

Crismale JF, Ahmad J
Gastrointest Endosc Clin N Am 2019 Apr;29(2):237-256. Epub 2019 Feb 2 doi: 10.1016/j.giec.2018.11.003. PMID: 30846151

Definition and classification of chyle leak after pancreatic operation: A consensus statement by the International Study Group on Pancreatic Surgery.

Besselink MG, van Rijssen LB, Bassi C, Dervenis C, Montorsi M, Adham M, Asbun HJ, Bockhorn M, Strobel O, Büchler MW, Busch OR, Charnley RM, Conlon KC, Fernández-Cruz L, Fingerhut A, Friess H, Izbicki JR, Lillemoe KD, Neoptolemos JP, Sarr MG, Shrikhande SV, Sitarz R, Vollmer CM, Yeo CJ, Hartwig W, Wolfgang CL, Gouma DJ; International Study Group on Pancreatic Surgery
Surgery 2017 Feb;161(2):365-372. Epub 2016 Sep 28 doi: 10.1016/j.surg.2016.06.058. PMID: 27692778

See all (51)

Recent clinical studies

Etiology

Late postpancreatectomy hemorrhage from the gastroduodenal artery stump into an insufficient hepaticojejunostomy: a case report.

Zeyara A, Tingstedt B, Andersson B
J Med Case Rep 2021 Apr 29;15(1):245. doi: 10.1186/s13256-021-02743-3. PMID: 33926546 Free PMC Article

Complications of biliary-enteric anastomoses.

Kadaba RS, Bowers KA, Khorsandi S, Hutchins RR, Abraham AT, Sarker SJ, Bhattacharya S, Kocher HM
Ann R Coll Surg Engl 2017 Mar;99(3):210-215. Epub 2016 Sep 23 doi: 10.1308/rcsann.2016.0293. PMID: 27659373 Free PMC Article

Fibrin glue and biliary anastomotic leak after liver transplant.

Topaloğlu S, Çalık A, Kalaycı O, Sağlam K, Yazıcı A, Aydın C
Exp Clin Transplant 2014 Mar;12 Suppl 1:76-80. PMID: 24635798

Biliary self-expandable metal stents do not adversely affect pancreaticoduodenectomy.

Cavell LK, Allen PJ, Vinoya C, Eaton AA, Gonen M, Gerdes H, Mendelsohn RB, D'Angelica MI, Kingham TP, Fong Y, Dematteo R, Jarnagin WR, Kurtz RC, Schattner MA
Am J Gastroenterol 2013 Jul;108(7):1168-73. Epub 2013 Apr 2 doi: 10.1038/ajg.2013.93. PMID: 23545711 Free PMC Article

Vascular anomalies encountered during pancreatoduodenectomy: do they influence outcomes?

Shukla PJ, Barreto SG, Kulkarni A, Nagarajan G, Fingerhut A
Ann Surg Oncol 2010 Jan;17(1):186-93. Epub 2009 Oct 17 doi: 10.1245/s10434-009-0757-1. PMID: 19838756

See all (5)

Diagnosis

Late postpancreatectomy hemorrhage from the gastroduodenal artery stump into an insufficient hepaticojejunostomy: a case report.

Zeyara A, Tingstedt B, Andersson B
J Med Case Rep 2021 Apr 29;15(1):245. doi: 10.1186/s13256-021-02743-3. PMID: 33926546 Free PMC Article

Fibrin glue and biliary anastomotic leak after liver transplant.

Topaloğlu S, Çalık A, Kalaycı O, Sağlam K, Yazıcı A, Aydın C
Exp Clin Transplant 2014 Mar;12 Suppl 1:76-80. PMID: 24635798

See all (2)

Therapy

Late postpancreatectomy hemorrhage from the gastroduodenal artery stump into an insufficient hepaticojejunostomy: a case report.

Zeyara A, Tingstedt B, Andersson B
J Med Case Rep 2021 Apr 29;15(1):245. doi: 10.1186/s13256-021-02743-3. PMID: 33926546 Free PMC Article

Fibrin glue and biliary anastomotic leak after liver transplant.

Topaloğlu S, Çalık A, Kalaycı O, Sağlam K, Yazıcı A, Aydın C
Exp Clin Transplant 2014 Mar;12 Suppl 1:76-80. PMID: 24635798

Biliary self-expandable metal stents do not adversely affect pancreaticoduodenectomy.

Defining the role of surgery for complications after pancreatoduodenectomy.

Shukla PJ, Barreto SG, Mohandas KM, Shrikhande SV
ANZ J Surg 2009 Jan-Feb;79(1-2):33-7. doi: 10.1111/j.1445-2197.2008.04794.x. PMID: 19183376

See all (4)

Prognosis

Pediatric living donor liver transplant for Budd-Chiari syndrome using a cryopreserved pulmonary vein graft for retro-hepatic vena cava reconstruction: A case report.

Yang XY, Le-Nguyen A, Alvarez F, Rong ZX, Borsuk D, Piché N, Lallier M, Beaunoyer M
Pediatr Transplant 2024 Feb;28(1):e14674. Epub 2023 Dec 6 doi: 10.1111/petr.14674. PMID: 38054589

Complications of biliary-enteric anastomoses.

A case of Aspergillus fumigatus peritonitis complicating liver transplantation.

Sartin JS, Wilhelm MP, Keating MR, Batts K, Krom RA
Eur J Clin Microbiol Infect Dis 1994 Jan;13(1):25-8. doi: 10.1007/BF02026119. PMID: 8168555

See all (3)