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Idiopathic Membranous Glomerulopathy

MedGen UID:
926453
•Concept ID:
C4288921
•
Disease or Syndrome

Definition

Chronic degenerative changes in the kidney characterized by thickened and inflamed glomeruli and proteinurea, the cause of which is unknown. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIdiopathic Membranous Glomerulopathy

Professional guidelines

PubMed

Treatment of idiopathic membranous glomerulopathy.
Remuzzi G, Schieppati A, Garattini S
Curr Opin Nephrol Hypertens 1994 Mar;3(2):155-63. doi: 10.1097/00041552-199403000-00005. PMID: 7842265

Recent clinical studies

Etiology

Phospholipase A2 receptor staining in pediatric idiopathic membranous glomerulopathy.
Cossey LN, Walker PD, Larsen CP
Pediatr Nephrol 2013 Dec;28(12):2307-11. Epub 2013 Aug 2 doi: 10.1007/s00467-013-2574-9. PMID: 23903693
CD45RO and CD45RA positive cell populations in idiopathic membranous and IgA glomerulopathy.
Lee AH, Bass PS, Williams JH, Evans B, Jones DB, Theaker JM, Davies DR
J Clin Pathol 1996 Jan;49(1):43-7. doi: 10.1136/jcp.49.1.43. PMID: 8666684Free PMC Article
A review of therapeutic studies of idiopathic membranous glomerulopathy.
Hogan SL, Muller KE, Jennette JC, Falk RJ
Am J Kidney Dis 1995 Jun;25(6):862-75. doi: 10.1016/0272-6386(95)90568-5. PMID: 7771482
Treatment of idiopathic membranous glomerulopathy.
Remuzzi G, Schieppati A, Garattini S
Curr Opin Nephrol Hypertens 1994 Mar;3(2):155-63. doi: 10.1097/00041552-199403000-00005. PMID: 7842265
Renal vein thrombosis in idiopathic membranous glomerulopathy and nephrotic syndrome: incidence and significance.
Wagoner RD, Stanson AW, Holley KE, Winter CS
Kidney Int 1983 Feb;23(2):368-74. doi: 10.1038/ki.1983.28. PMID: 6842962

Diagnosis

Phospholipase A2 receptor staining in pediatric idiopathic membranous glomerulopathy.
Cossey LN, Walker PD, Larsen CP
Pediatr Nephrol 2013 Dec;28(12):2307-11. Epub 2013 Aug 2 doi: 10.1007/s00467-013-2574-9. PMID: 23903693
Immunofluorescence on pronase-digested paraffin sections: a valuable salvage technique for renal biopsies.
Nasr SH, Galgano SJ, Markowitz GS, Stokes MB, D'Agati VD
Kidney Int 2006 Dec;70(12):2148-51. Epub 2006 Oct 25 doi: 10.1038/sj.ki.5001990. PMID: 17063172
Idiopathic membranous glomerulopathy in Canadian children: a clinicopathologic study.
Latham P, Poucell S, Koresaar A, Arbus G, Baumal R
J Pediatr 1982 Nov;101(5):682-5. doi: 10.1016/s0022-3476(82)80290-4. PMID: 7131140
Idiopathic membranous glomerulopathy preceding the emergence of systemic lupus erythematosus in two children.
Kallen RJ, Lee SK, Aronson AJ, Spargo BH
J Pediatr 1977 Jan;90(1):72-6. doi: 10.1016/s0022-3476(77)80767-1. PMID: 830897

Therapy

A review of therapeutic studies of idiopathic membranous glomerulopathy.
Hogan SL, Muller KE, Jennette JC, Falk RJ
Am J Kidney Dis 1995 Jun;25(6):862-75. doi: 10.1016/0272-6386(95)90568-5. PMID: 7771482
Treatment of idiopathic membranous glomerulopathy.
Remuzzi G, Schieppati A, Garattini S
Curr Opin Nephrol Hypertens 1994 Mar;3(2):155-63. doi: 10.1097/00041552-199403000-00005. PMID: 7842265
Antiproteinuric drugs in patients with idiopathic membranous glomerulopathy.
Gansevoort RT, Heeg JE, Vriesendorp R, de Zeeuw D, de Jong PE
Nephrol Dial Transplant 1992;7 Suppl 1:91-6. PMID: 1337189
What is the basis for the use of steroids in the treatment of idiopathic membranous nephropathy?
Garattini S, Bertani T, Remuzzi G
Nephron 1987;45(1):1-6. doi: 10.1159/000184062. PMID: 3543708
Corticosteroid therapy is beneficial in adults with idiopathic membranous glomerulopathy.
Glassock RJ
Am J Kidney Dis 1982 May;1(6):376-85. doi: 10.1016/s0272-6386(82)80011-5. PMID: 7091153

Prognosis

Phospholipase A2 receptor staining in pediatric idiopathic membranous glomerulopathy.
Cossey LN, Walker PD, Larsen CP
Pediatr Nephrol 2013 Dec;28(12):2307-11. Epub 2013 Aug 2 doi: 10.1007/s00467-013-2574-9. PMID: 23903693
CD45RO and CD45RA positive cell populations in idiopathic membranous and IgA glomerulopathy.
Lee AH, Bass PS, Williams JH, Evans B, Jones DB, Theaker JM, Davies DR
J Clin Pathol 1996 Jan;49(1):43-7. doi: 10.1136/jcp.49.1.43. PMID: 8666684Free PMC Article
A review of therapeutic studies of idiopathic membranous glomerulopathy.
Hogan SL, Muller KE, Jennette JC, Falk RJ
Am J Kidney Dis 1995 Jun;25(6):862-75. doi: 10.1016/0272-6386(95)90568-5. PMID: 7771482
Renal vein thrombosis in idiopathic membranous glomerulopathy and nephrotic syndrome: incidence and significance.
Wagoner RD, Stanson AW, Holley KE, Winter CS
Kidney Int 1983 Feb;23(2):368-74. doi: 10.1038/ki.1983.28. PMID: 6842962
Idiopathic membranous glomerulopathy in Canadian children: a clinicopathologic study.
Latham P, Poucell S, Koresaar A, Arbus G, Baumal R
J Pediatr 1982 Nov;101(5):682-5. doi: 10.1016/s0022-3476(82)80290-4. PMID: 7131140

Clinical prediction guides

TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy.
Hofstra JM, Coenen MJ, Schijvenaars MM, Berden JH, van der Vlag J, Hoefsloot LH, Knoers NV, Wetzels JF, Nijenhuis T
PLoS One 2014;9(7):e102065. Epub 2014 Jul 14 doi: 10.1371/journal.pone.0102065. PMID: 25019165Free PMC Article
Phospholipase A2 receptor staining in pediatric idiopathic membranous glomerulopathy.
Cossey LN, Walker PD, Larsen CP
Pediatr Nephrol 2013 Dec;28(12):2307-11. Epub 2013 Aug 2 doi: 10.1007/s00467-013-2574-9. PMID: 23903693
A review of therapeutic studies of idiopathic membranous glomerulopathy.
Hogan SL, Muller KE, Jennette JC, Falk RJ
Am J Kidney Dis 1995 Jun;25(6):862-75. doi: 10.1016/0272-6386(95)90568-5. PMID: 7771482
Antiproteinuric drugs in patients with idiopathic membranous glomerulopathy.
Gansevoort RT, Heeg JE, Vriesendorp R, de Zeeuw D, de Jong PE
Nephrol Dial Transplant 1992;7 Suppl 1:91-6. PMID: 1337189
Renal vein thrombosis in idiopathic membranous glomerulopathy and nephrotic syndrome: incidence and significance.
Wagoner RD, Stanson AW, Holley KE, Winter CS
Kidney Int 1983 Feb;23(2):368-74. doi: 10.1038/ki.1983.28. PMID: 6842962

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