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Warthin-Like Variant Thyroid Gland Papillary Carcinoma

MedGen UID:
925508
•Concept ID:
C4287976
•
Neoplastic Process
Synonym: Warthin Tumor-Like Variant Thyroid Gland Papillary Carcinoma

Definition

A rare variant of papillary thyroid gland carcinoma characterized by the presence of eosinophilic large cells lining the papillae and a brisk lymphoplasmacytic infiltrate in the papillary stalks. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVWarthin-Like Variant Thyroid Gland Papillary Carcinoma

Recent clinical studies

Etiology

Warthin-like and classic papillary thyroid cancer have similar clinical presentation and prognosis.
Olmos R, Muñoz F, Donoso F, López J, Bruera MJ, Ruiz-Esquide M, Mosso L, Lustig N, Solar A, Droppelmann N, Montero PH, González HE, Domínguez JM
Arch Endocrinol Metab 2021 May 18;64(5):542-547. doi: 10.20945/2359-3997000000270. PMID: 34033294Free PMC Article
Clinical and sonographic characteristics of Warthin-like variant papillary thyroid carcinomas.
Ning C, Koo JS, Kim EK, Lee S
Med Ultrason 2019 May 2;21(2):152-157. doi: 10.11152/mu-1870. PMID: 31063518
Warthin-like papillary thyroid carcinoma with immunoglobulin G4-positive plasma cells possibly related to Hashimoto's thyroiditis.
Hirokawa M, Nishihara E, Takada N, Higuchi M, Kotakemori M, Hayashi T, Miyauchi A
Endocr J 2018 Feb 26;65(2):175-180. Epub 2017 Nov 2 doi: 10.1507/endocrj.EJ17-0319. PMID: 29093307
Warthin-like variant of papillary thyroid carcinoma: single institution experience.
Jun HH, Kim SM, Hong SW, Lee YS, Chang HS, Park CS
ANZ J Surg 2016 Jun;86(6):492-4. Epub 2014 Jul 1 doi: 10.1111/ans.12725. PMID: 24981584
The Chernobyl thyroid cancer experience: pathology.
LiVolsi VA, Abrosimov AA, Bogdanova T, Fadda G, Hunt JL, Ito M, Rosai J, Thomas GA, Williams ED
Clin Oncol (R Coll Radiol) 2011 May;23(4):261-7. Epub 2011 Feb 18 doi: 10.1016/j.clon.2011.01.160. PMID: 21333507

Diagnosis

Warthin-like papillary carcinoma thyroid.
Kalantri SH, D'Cruze L, Barathi G, Singh BK
J Cancer Res Ther 2023 Jul-Sep;19(5):1471-1473. doi: 10.4103/jcrt.jcrt_1028_21. PMID: 37787334
Warthin-like papillary carcinoma: Case report.
Jakešová J, Boháč R, Betlach J
Cesk Patol 2023 Spring;59(1):23-25. PMID: 37072276
Cytomorphology of Warthin-like variant of papillary thyroid carcinoma: A diagnosis not to be missed.
Agrawal S, Singh A, Jat B, Phulware RH
Cytopathology 2021 Nov;32(6):840-842. Epub 2021 Aug 8 doi: 10.1111/cyt.13037. PMID: 34273219
Variants of Papillary Thyroid Carcinoma: Multiple Faces of a Familiar Tumor.
Sak SD
Turk Patoloji Derg 2015;31 Suppl 1:34-47. doi: 10.5146/tjpath.2015.01313. PMID: 26177316
Sonographic and cytopathologic correlation of papillary thyroid carcinoma variants.
Lee JH, Shin JH, Lee HW, Oh YL, Hahn SY, Ko EY
J Ultrasound Med 2015 Jan;34(1):1-15. doi: 10.7863/ultra.34.1.1. PMID: 25542934

Prognosis

Warthin-like papillary carcinoma thyroid.
Kalantri SH, D'Cruze L, Barathi G, Singh BK
J Cancer Res Ther 2023 Jul-Sep;19(5):1471-1473. doi: 10.4103/jcrt.jcrt_1028_21. PMID: 37787334
Warthin-like papillary carcinoma: Case report.
Jakešová J, Boháč R, Betlach J
Cesk Patol 2023 Spring;59(1):23-25. PMID: 37072276
Warthin-like and classic papillary thyroid cancer have similar clinical presentation and prognosis.
Olmos R, Muñoz F, Donoso F, López J, Bruera MJ, Ruiz-Esquide M, Mosso L, Lustig N, Solar A, Droppelmann N, Montero PH, González HE, Domínguez JM
Arch Endocrinol Metab 2021 May 18;64(5):542-547. doi: 10.20945/2359-3997000000270. PMID: 34033294Free PMC Article
Variants of Papillary Thyroid Carcinoma: Multiple Faces of a Familiar Tumor.
Sak SD
Turk Patoloji Derg 2015;31 Suppl 1:34-47. doi: 10.5146/tjpath.2015.01313. PMID: 26177316
Sonographic and cytopathologic correlation of papillary thyroid carcinoma variants.
Lee JH, Shin JH, Lee HW, Oh YL, Hahn SY, Ko EY
J Ultrasound Med 2015 Jan;34(1):1-15. doi: 10.7863/ultra.34.1.1. PMID: 25542934

Clinical prediction guides

TROP2: a potential marker in diagnosis of thyroid neoplasms.
Turan Z, Erkılıç S
Ir J Med Sci 2023 Feb;192(1):99-103. Epub 2022 Mar 30 doi: 10.1007/s11845-022-02976-1. PMID: 35355197
CD56 Expression in Papillary Thyroid Carcinoma Is Highly Dependent on the Histologic Subtype: A Potential Diagnostic Pitfall.
Cho U, Kim Y, Jeon S, Jung CK
Appl Immunohistochem Mol Morphol 2022 May-Jun 01;30(5):389-396. Epub 2022 Mar 1 doi: 10.1097/PAI.0000000000001015. PMID: 35510774
Clinical and sonographic characteristics of Warthin-like variant papillary thyroid carcinomas.
Ning C, Koo JS, Kim EK, Lee S
Med Ultrason 2019 May 2;21(2):152-157. doi: 10.11152/mu-1870. PMID: 31063518
Warthin-like variant of papillary thyroid carcinoma: single institution experience.
Jun HH, Kim SM, Hong SW, Lee YS, Chang HS, Park CS
ANZ J Surg 2016 Jun;86(6):492-4. Epub 2014 Jul 1 doi: 10.1111/ans.12725. PMID: 24981584
Variants of Papillary Thyroid Carcinoma: Multiple Faces of a Familiar Tumor.
Sak SD
Turk Patoloji Derg 2015;31 Suppl 1:34-47. doi: 10.5146/tjpath.2015.01313. PMID: 26177316

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