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Ependymal cyst

MedGen UID:
90929
Concept ID:
C0338599
Finding
Synonym: Ependymal Cyst
SNOMED CT: Ependymal cyst (230792007)

Definition

Glioependymal/ependymal cyst is a rare central nervous system malformation defined as a subarachnoid, supratentorial, interventricular or intraspinal, sometimes intracerebral or intramedullar cyst with an internal ependymal lining, possibly surrounded by glial tissue. It may be an incidental finding or may present at different ages with clinical features depending on its size and location. It may distort adjacent brain structures and cause macrocephaly, ventriculomegaly, hydrocephalus, focal neurological signs and other signs and symptoms. In some cases, it is associated with other cerebral malformations (e.g. corpus callosum agenesis, polymicrogyria, heterotopias). [from ORPHANET]

Term Hierarchy

Professional guidelines

PubMed

Chakravarthi SS, Kassam AB, Fukui MB, Monroy-Sosa A, Rothong N, Cunningham J, Jennings JE, Guenther N, Connelly J, Kaemmerer T, Nash KC, Lindsay M, Rissell J, Celix JM, Rovin RA
Oper Neurosurg (Hagerstown) 2019 Aug 1;17(2):208-226. doi: 10.1093/ons/opy405. PMID: 30753637

Recent clinical studies

Etiology

Xie T, Qian J, Lu Y, Jiang Y, Wan Z, Zhang L, Luo C
J Clin Neurosci 2014 Jul;21(7):1196-204. Epub 2014 Jan 2 doi: 10.1016/j.jocn.2013.10.025. PMID: 24674700
Saini AG, Singhi P, Bharti B, Vasishta RK, Saxena AK, Mohindra S
Indian J Pediatr 2013 Jun;80(6):509-12. Epub 2012 May 10 doi: 10.1007/s12098-012-0771-3. PMID: 22573196
Kuo MF, Tsai Y, Hsu WM, Chen RS, Tu YK, Wang HS
J Neurosurg 2007 Mar;106(3 Suppl):201-4. doi: 10.3171/ped.2007.106.3.201. PMID: 17465385
Kumar R, Singh V
Pediatr Neurosurg 2004 Jan-Feb;40(1):16-22. doi: 10.1159/000076572. PMID: 15007224
Mampalam TJ, Harsh GR 4th, Tien RD, Dillon WP, Wilson CB
Surg Neurol 1991 Jan;35(1):14-9. doi: 10.1016/0090-3019(91)90196-g. PMID: 1983877

Diagnosis

Paulla Galdino Chaves J, Henrique Dallo Gallo B, Louise Gonçalves Souza E Silva N, Luvison Gomes da Silva L, Alberto Mattozo C
J Clin Neurosci 2022 May;99:10-16. Epub 2022 Feb 25 doi: 10.1016/j.jocn.2022.02.030. PMID: 35228087
Prieto R, Subhi-Issa I, Pascual JM
Clin Neuropathol 2013 May-Jun;32(3):183-8. doi: 10.5414/NP300563. PMID: 23254139
Savas Erdeve S, Ocal G, Berberoglu M, Siklar Z, Hacihamdioglu B, Evliyaoglu O, Fitoz S
J Pediatr Endocrinol Metab 2011;24(11-12):867-75. doi: 10.1515/jpem.2011.263. PMID: 22308834
Utsunomiya H, Yamashita S, Takano K, Ueda Y, Fujii A
Radiat Med 2006 Jul;24(6):471-81. doi: 10.1007/s11604-006-0049-7. PMID: 16958432
Mampalam TJ, Harsh GR 4th, Tien RD, Dillon WP, Wilson CB
Surg Neurol 1991 Jan;35(1):14-9. doi: 10.1016/0090-3019(91)90196-g. PMID: 1983877

Therapy

Ranjan R, Handa A, Choudhary A, Kumar S
Surg Neurol 2009 Aug;72(2):185-9. Epub 2008 Jul 9 doi: 10.1016/j.surneu.2008.04.008. PMID: 18617243
Schelper RL, Ramzy I, Durr N
Acta Cytol 1985 Jan-Feb;29(1):44-8. PMID: 3855586

Prognosis

Paulla Galdino Chaves J, Henrique Dallo Gallo B, Louise Gonçalves Souza E Silva N, Luvison Gomes da Silva L, Alberto Mattozo C
J Clin Neurosci 2022 May;99:10-16. Epub 2022 Feb 25 doi: 10.1016/j.jocn.2022.02.030. PMID: 35228087
El Damaty A, Marx S, Fleck S, Schroeder HW
World Neurosurg 2017 Jan;97:383-389. Epub 2016 Oct 14 doi: 10.1016/j.wneu.2016.10.021. PMID: 27751924
Xie T, Qian J, Lu Y, Jiang Y, Wan Z, Zhang L, Luo C
J Clin Neurosci 2014 Jul;21(7):1196-204. Epub 2014 Jan 2 doi: 10.1016/j.jocn.2013.10.025. PMID: 24674700
Kuo MF, Tsai Y, Hsu WM, Chen RS, Tu YK, Wang HS
J Neurosurg 2007 Mar;106(3 Suppl):201-4. doi: 10.3171/ped.2007.106.3.201. PMID: 17465385
Wisoff HS, Ghatak NR
J Neurol Neurosurg Psychiatry 1971 Oct;34(5):546-50. doi: 10.1136/jnnp.34.5.546. PMID: 5122382Free PMC Article

Clinical prediction guides

Chakravarthi SS, Kassam AB, Fukui MB, Monroy-Sosa A, Rothong N, Cunningham J, Jennings JE, Guenther N, Connelly J, Kaemmerer T, Nash KC, Lindsay M, Rissell J, Celix JM, Rovin RA
Oper Neurosurg (Hagerstown) 2019 Aug 1;17(2):208-226. doi: 10.1093/ons/opy405. PMID: 30753637
Savas Erdeve S, Ocal G, Berberoglu M, Siklar Z, Hacihamdioglu B, Evliyaoglu O, Fitoz S
J Pediatr Endocrinol Metab 2011;24(11-12):867-75. doi: 10.1515/jpem.2011.263. PMID: 22308834
Aleman J, Jokura H, Higano S, Akabane A, Shirane R, Yoshimoto T
Neurosurgery 2001 Jun;48(6):1291-5; discussion 1295-6. doi: 10.1097/00006123-200106000-00021. PMID: 11383732
Jallo GI, Friedlander DR, Kelly PJ, Wisoff JH, Grumet M, Zagzag D
Neurosurgery 1997 Nov;41(5):1052-9. doi: 10.1097/00006123-199711000-00007. PMID: 9361058
Takeuchi T, Kumakawa H, Kimura S, Satoh S, Kobayashi M
Neurol Med Chir (Tokyo) 1989 May;29(5):417-23. doi: 10.2176/nmc.29.417. PMID: 2477743

Recent systematic reviews

Paulla Galdino Chaves J, Henrique Dallo Gallo B, Louise Gonçalves Souza E Silva N, Luvison Gomes da Silva L, Alberto Mattozo C
J Clin Neurosci 2022 May;99:10-16. Epub 2022 Feb 25 doi: 10.1016/j.jocn.2022.02.030. PMID: 35228087
Robles LA, Paez JM, Ayala D, Boleaga-Duran B
Acta Neurochir (Wien) 2018 Jul;160(7):1439-1449. Epub 2018 May 25 doi: 10.1007/s00701-018-3566-0. PMID: 29802560

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