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Astroblastoma

MedGen UID:
90811
Concept ID:
C0334587
Neoplastic Process
Synonym: Cerebral astroblastoma
SNOMED CT: Astroblastoma (48952003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0016707
Orphanet: ORPHA251679

Definition

A very rare glial neoplasm of the central nervous system, most often with an intra-axial peripheral supratentorial location in one hemisphere of the frontal or parietal lobes and usually presenting in infants and young adults with symptoms of vomiting, loss of consciousness, epileptic seizures and headaches. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAstroblastoma
Follow this link to review classifications for Astroblastoma in Orphanet.

Professional guidelines

PubMed

Rosenberg T, Yeo KK, Mauguen A, Alexandrescu S, Prabhu SP, Tsai JW, Malinowski S, Joshirao M, Parikh K, Farouk Sait S, Rosenblum MK, Benhamida JK, Michaiel G, Tran HN, Dahiya S, Kachurak K, Friedman GK, Krystal JI, Huang MA, Margol AS, Wright KD, Aguilera D, MacDonald TJ, Chi SN, Karajannis MA
Neuro Oncol 2022 Nov 2;24(11):1964-1975. doi: 10.1093/neuonc/noac096. PMID: 35397478Free PMC Article
Jeon C, Kim B, Choi JW
J Neurosurg Pediatr 2022 May 1;29(5):513-519. Epub 2022 Feb 18 doi: 10.3171/2022.1.PEDS21389. PMID: 35180693
Merfeld EC, Dahiya S, Perkins SM
CNS Oncol 2018 Apr;7(2):CNS13. Epub 2018 Apr 30 doi: 10.2217/cns-2017-0038. PMID: 29708401Free PMC Article

Recent clinical studies

Etiology

Köy Y, Tihan T
Indian J Pathol Microbiol 2022 May;65(Supplement):S33-S41. doi: 10.4103/ijpm.ijpm_1019_21. PMID: 35562132
Kurokawa R, Baba A, Kurokawa M, Ota Y, Hassan O, Capizzano A, Kim J, Johnson T, Srinivasan A, Moritani T
J Neuroimaging 2022 Mar;32(2):201-212. Epub 2021 Nov 23 doi: 10.1111/jon.12948. PMID: 34816541
Teleanu DM, Ilieşiu A, Bălaşa AF, Teleanu RI, Bogaciu NŞ
Rom J Morphol Embryol 2018;59(4):1239-1245. PMID: 30845307
Denaro L, Gardiman M, Calderone M, Rossetto M, Ciccarino P, Giangaspero F, Perilongo G, d'Avella D
J Neurosurg Pediatr 2008 Feb;1(2):152-5. doi: 10.3171/PED/2008/1/2/152. PMID: 18352788
Caroli E, Salvati M, Esposito V, Orlando ER, Giangaspero F
Acta Neurochir (Wien) 2004 Jun;146(6):629-33. Epub 2004 Apr 13 doi: 10.1007/s00701-004-0230-7. PMID: 15168232

Diagnosis

Sun D, Liu J, Xiao L, Guan H
Clin Neuropathol 2023 Jan-Feb;42(1):30-39. doi: 10.5414/NP301497. PMID: 36366964
Sarper B, Yaprak Bayrak B, Halis H, Alparslan B, Yeni Bayraktar H
Balkan Med J 2020 Jun 1;37(4):224-225. Epub 2020 Mar 26 doi: 10.4274/balkanmedj.galenos.2020.2019.11.39. PMID: 32212579Free PMC Article
Hammas N, Senhaji N, Alaoui Lamrani MY, Bennis S, Chaoui EM, El Fatemi H, Chbani L
J Med Case Rep 2018 Apr 21;12(1):102. doi: 10.1186/s13256-018-1623-1. PMID: 29678196Free PMC Article
Cunningham DA, Lowe LH, Shao L, Acosta NR
Pediatr Radiol 2016 Aug;46(9):1301-8. Epub 2016 Apr 5 doi: 10.1007/s00247-016-3607-x. PMID: 27048363
Soffietti R, Rudà R, Reardon D
Handb Clin Neurol 2016;134:399-415. doi: 10.1016/B978-0-12-802997-8.00024-4. PMID: 26948368

Therapy

Rosenberg T, Yeo KK, Mauguen A, Alexandrescu S, Prabhu SP, Tsai JW, Malinowski S, Joshirao M, Parikh K, Farouk Sait S, Rosenblum MK, Benhamida JK, Michaiel G, Tran HN, Dahiya S, Kachurak K, Friedman GK, Krystal JI, Huang MA, Margol AS, Wright KD, Aguilera D, MacDonald TJ, Chi SN, Karajannis MA
Neuro Oncol 2022 Nov 2;24(11):1964-1975. doi: 10.1093/neuonc/noac096. PMID: 35397478Free PMC Article
Sarper B, Yaprak Bayrak B, Halis H, Alparslan B, Yeni Bayraktar H
Balkan Med J 2020 Jun 1;37(4):224-225. Epub 2020 Mar 26 doi: 10.4274/balkanmedj.galenos.2020.2019.11.39. PMID: 32212579Free PMC Article
Dhawan S, Patil CG, Chen C, Venteicher AS
Cochrane Database Syst Rev 2020 Jan 20;1(1):CD009229. doi: 10.1002/14651858.CD009229.pub3. PMID: 31958162Free PMC Article
Agawa Y, Wataya T
Childs Nerv Syst 2018 May;34(5):971-975. Epub 2018 Jan 5 doi: 10.1007/s00381-017-3714-5. PMID: 29305683
Sarmiento JM, Venteicher AS, Patil CG
Cochrane Database Syst Rev 2015 Jun 29;6(6):CD009229. doi: 10.1002/14651858.CD009229.pub2. PMID: 26118544Free PMC Article

Prognosis

Lehman NL
J Neurooncol 2023 Feb;161(3):425-439. Epub 2023 Jan 6 doi: 10.1007/s11060-022-04222-1. PMID: 36604386Free PMC Article
Sun D, Liu J, Xiao L, Guan H
Clin Neuropathol 2023 Jan-Feb;42(1):30-39. doi: 10.5414/NP301497. PMID: 36366964
Kurokawa R, Baba A, Kurokawa M, Ota Y, Hassan O, Capizzano A, Kim J, Johnson T, Srinivasan A, Moritani T
J Neuroimaging 2022 Mar;32(2):201-212. Epub 2021 Nov 23 doi: 10.1111/jon.12948. PMID: 34816541
Soffietti R, Rudà R, Reardon D
Handb Clin Neurol 2016;134:399-415. doi: 10.1016/B978-0-12-802997-8.00024-4. PMID: 26948368
Sughrue ME, Choi J, Rutkowski MJ, Aranda D, Kane AJ, Barani IJ, Parsa AT
J Clin Neurosci 2011 Jun;18(6):750-4. Epub 2011 Apr 19 doi: 10.1016/j.jocn.2010.11.007. PMID: 21507653

Clinical prediction guides

Sun D, Liu J, Xiao L, Guan H
Clin Neuropathol 2023 Jan-Feb;42(1):30-39. doi: 10.5414/NP301497. PMID: 36366964
Kurokawa R, Baba A, Kurokawa M, Ota Y, Hassan O, Capizzano A, Kim J, Johnson T, Srinivasan A, Moritani T
J Neuroimaging 2022 Mar;32(2):201-212. Epub 2021 Nov 23 doi: 10.1111/jon.12948. PMID: 34816541
Zschernack V, Jünger ST, Mynarek M, Rutkowski S, Garre ML, Ebinger M, Neu M, Faber J, Erdlenbruch B, Claviez A, Bielack S, Brozou T, Frühwald MC, Dörner E, Dreschmann V, Stock A, Solymosi L, Hench J, Frank S, Vokuhl C, Waha A, Andreiuolo F, Pietsch T
Acta Neuropathol 2021 Mar;141(3):455-466. Epub 2021 Jan 22 doi: 10.1007/s00401-020-02260-5. PMID: 33481105Free PMC Article
Yapıcıer Ö, Demir MK, Özdamarlar U, Kılıç D, Akakın A, Kılıç T
Childs Nerv Syst 2019 Jul;35(7):1251-1255. Epub 2019 Mar 12 doi: 10.1007/s00381-019-04113-3. PMID: 30859299
Janz C, Buhl R
Clin Neurol Neurosurg 2014 Oct;125:114-24. Epub 2014 Jul 21 doi: 10.1016/j.clineuro.2014.07.013. PMID: 25108699

Recent systematic reviews

Kurokawa R, Baba A, Kurokawa M, Ota Y, Hassan O, Capizzano A, Kim J, Johnson T, Srinivasan A, Moritani T
J Neuroimaging 2022 Mar;32(2):201-212. Epub 2021 Nov 23 doi: 10.1111/jon.12948. PMID: 34816541
Andrews LJ, Thornton ZA, Saincher SS, Yao IY, Dawson S, McGuinness LA, Jones HE, Jefferies S, Short SC, Cheng HY, McAleenan A, Higgins JPT, Kurian KM
Neuro Oncol 2022 Apr 1;24(4):528-540. doi: 10.1093/neuonc/noab247. PMID: 34718782Free PMC Article
Dhawan S, Patil CG, Chen C, Venteicher AS
Cochrane Database Syst Rev 2020 Jan 20;1(1):CD009229. doi: 10.1002/14651858.CD009229.pub3. PMID: 31958162Free PMC Article
Cunningham DA, Lowe LH, Shao L, Acosta NR
Pediatr Radiol 2016 Aug;46(9):1301-8. Epub 2016 Apr 5 doi: 10.1007/s00247-016-3607-x. PMID: 27048363
Sarmiento JM, Venteicher AS, Patil CG
Cochrane Database Syst Rev 2015 Jun 29;6(6):CD009229. doi: 10.1002/14651858.CD009229.pub2. PMID: 26118544Free PMC Article

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