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Squamous Cell Carcinoma In Situ with Questionable Stromal Invasion

MedGen UID:
90751
•Concept ID:
C0334251
•
Neoplastic Process
Synonyms: Epidermoid carcinoma in situ with questionable stromal invasion; Squamous cell carcinoma in situ with questionable stromal invasion
SNOMED CT: Squamous cell carcinoma in situ with questionable stromal invasion (5688000); Epidermoid carcinoma in situ with questionable stromal invasion (5688000)

Definition

A malignant epithelial neoplasm involving all the layers of the squamous epithelium, but it is not certain if it is confined to the squamous epithelium or it has invaded the basement membrane and the underlying stroma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSquamous Cell Carcinoma In Situ with Questionable Stromal Invasion

Recent clinical studies

Etiology

Microinvasive carcinoma of the uterine cervix: A long-term followup study of eighty cases.
Christopherson WM, Gray LA, Parker JE
Cancer 1976 Aug;38(2):629-32. doi: 10.1002/1097-0142(197608)38:2<629::aid-cncr2820380202>3.0.co;2-e. PMID: 974988

Diagnosis

Distribution of type IV collagen immunoreactivity to assess questionable early stromal invasion.
Stewart CJ, McNicol AM
J Clin Pathol 1992 Jan;45(1):9-15. doi: 10.1136/jcp.45.1.9. PMID: 1740529Free PMC Article
An immunoperoxidase study of laminin and type IV collagen distribution in carcinoma of the cervix and vulva.
Ehrmann RL, Dwyer IM, Yavner D, Hancock WW
Obstet Gynecol 1988 Aug;72(2):257-62. PMID: 3292982

Prognosis

Microinvasive carcinoma of the uterine cervix: A long-term followup study of eighty cases.
Christopherson WM, Gray LA, Parker JE
Cancer 1976 Aug;38(2):629-32. doi: 10.1002/1097-0142(197608)38:2<629::aid-cncr2820380202>3.0.co;2-e. PMID: 974988

Clinical prediction guides

Distribution of type IV collagen immunoreactivity to assess questionable early stromal invasion.
Stewart CJ, McNicol AM
J Clin Pathol 1992 Jan;45(1):9-15. doi: 10.1136/jcp.45.1.9. PMID: 1740529Free PMC Article

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