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Abnormal peripheral nervous system ganglion morphology

MedGen UID:
893149
•Concept ID:
C4073194
•
Anatomical Abnormality
Synonym: Abnormality of ganglion of peripheral nervous system
 
HPO: HP:0410015

Definition

An abnormality of nerve cell cluster or a group of nerve cell bodies located in the peripheral autonomic nervous system. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal peripheral nervous system ganglion morphology

Professional guidelines

PubMed

Targeting voltage-gated sodium channels for treatment for chronic visceral pain.
Qi FH, Zhou YL, Xu GY
World J Gastroenterol 2011 May 21;17(19):2357-64. doi: 10.3748/wjg.v17.i19.2357. PMID: 21633634Free PMC Article
Hirschsprung's disease: current management and prospects for transplantation of enteric nervous system progenitor cells.
Theocharatos S, Kenny SE
Early Hum Dev 2008 Dec;84(12):801-4. Epub 2008 Oct 2 doi: 10.1016/j.earlhumdev.2008.09.007. PMID: 18835114
Evaluation and management of autonomic nervous system disorders.
Klein CM
Semin Neurol 2008 Apr;28(2):195-204. doi: 10.1055/s-2008-1062263. PMID: 18351521

Recent clinical studies

Etiology

Superior segmental optic nerve hypoplasia: A review.
Wu JH, Lin CW, Liu CH, Weinreb RN, Welsbie DS
Surv Ophthalmol 2022 Sep-Oct;67(5):1467-1475. Epub 2022 Feb 18 doi: 10.1016/j.survophthal.2022.02.008. PMID: 35189184
Retinal Manifestations of Idiopathic Intracranial Hypertension.
Nichani P, Micieli JA
Ophthalmol Retina 2021 May;5(5):429-437. Epub 2020 Aug 26 doi: 10.1016/j.oret.2020.08.016. PMID: 32860958
Meniere's disease.
Nakashima T, Pyykkö I, Arroll MA, Casselbrant ML, Foster CA, Manzoor NF, Megerian CA, Naganawa S, Young YH
Nat Rev Dis Primers 2016 May 12;2:16028. doi: 10.1038/nrdp.2016.28. PMID: 27170253
Neuroimaging in Sensory Neuronopathy.
Casseb RF, Martinez AR, de Paiva JL, França MC Jr
J Neuroimaging 2015 Sep-Oct;25(5):704-9. Epub 2015 Feb 10 doi: 10.1111/jon.12210. PMID: 25678358
Neuroacanthocytosis.
Walker RH, Jung HH, Danek A
Handb Clin Neurol 2011;100:141-51. doi: 10.1016/B978-0-444-52014-2.00007-0. PMID: 21496574

Diagnosis

Congenital Myenteric Hypoganglionosis.
Kapur RP, Bellizzi AM, Bond S, Chen H, Han JS, LeGallo RD, Midgen C, Poulin AA, Uddin N, Warren M, Velázquez Vega JE, Zuppan CW
Am J Surg Pathol 2021 Aug 1;45(8):1047-1060. doi: 10.1097/PAS.0000000000001670. PMID: 33492848
Meniere's disease.
Nakashima T, Pyykkö I, Arroll MA, Casselbrant ML, Foster CA, Manzoor NF, Megerian CA, Naganawa S, Young YH
Nat Rev Dis Primers 2016 May 12;2:16028. doi: 10.1038/nrdp.2016.28. PMID: 27170253
Auditory neuropathy--neural and synaptic mechanisms.
Moser T, Starr A
Nat Rev Neurol 2016 Mar;12(3):135-49. Epub 2016 Feb 19 doi: 10.1038/nrneurol.2016.10. PMID: 26891769
Sensory neuron diseases.
Sghirlanzoni A, Pareyson D, Lauria G
Lancet Neurol 2005 Jun;4(6):349-61. doi: 10.1016/S1474-4422(05)70096-X. PMID: 15907739
Hirschprung's disease.
Sullivan PB
Arch Dis Child 1996 Jan;74(1):5-7. doi: 10.1136/adc.74.1.5. PMID: 8660047Free PMC Article

Therapy

Plasticity of vagal afferent signaling in the gut.
Grabauskas G, Owyang C
Medicina (Kaunas) 2017;53(2):73-84. Epub 2017 Apr 10 doi: 10.1016/j.medici.2017.03.002. PMID: 28454890Free PMC Article
Meniere's disease.
Nakashima T, Pyykkö I, Arroll MA, Casselbrant ML, Foster CA, Manzoor NF, Megerian CA, Naganawa S, Young YH
Nat Rev Dis Primers 2016 May 12;2:16028. doi: 10.1038/nrdp.2016.28. PMID: 27170253
Achalasia: new perspectives on an old disease.
Gyawali CP
Neurogastroenterol Motil 2016 Jan;28(1):4-11. doi: 10.1111/nmo.12750. PMID: 26690870
Painful sweating.
Goldstein DS, Pechnik S, Moak J, Eldadah B
Neurology 2004 Oct 26;63(8):1471-5. doi: 10.1212/01.wnl.0000142037.06255.a8. PMID: 15505167
Intestinal pseudo-obstruction.
Moss AA, Goldberg HI
CRC Crit Rev Radiol Sci 1972;3(3):363-87. PMID: 4146635

Prognosis

Superior segmental optic nerve hypoplasia: A review.
Wu JH, Lin CW, Liu CH, Weinreb RN, Welsbie DS
Surv Ophthalmol 2022 Sep-Oct;67(5):1467-1475. Epub 2022 Feb 18 doi: 10.1016/j.survophthal.2022.02.008. PMID: 35189184
Disorders of vision in multiple sclerosis.
Dhanapalaratnam R, Markoulli M, Krishnan AV
Clin Exp Optom 2022 Jan;105(1):3-12. Epub 2021 Aug 4 doi: 10.1080/08164622.2021.1947745. PMID: 34348598
Sensory neuronopathies: A case series and literature review.
Sancho Saldaña A, Mahdi-Rogers M, Hadden RD
J Peripher Nerv Syst 2021 Mar;26(1):66-74. Epub 2021 Jan 31 doi: 10.1111/jns.12433. PMID: 33491284
Retinal Manifestations of Idiopathic Intracranial Hypertension.
Nichani P, Micieli JA
Ophthalmol Retina 2021 May;5(5):429-437. Epub 2020 Aug 26 doi: 10.1016/j.oret.2020.08.016. PMID: 32860958
Sensory neuron diseases.
Sghirlanzoni A, Pareyson D, Lauria G
Lancet Neurol 2005 Jun;4(6):349-61. doi: 10.1016/S1474-4422(05)70096-X. PMID: 15907739

Clinical prediction guides

Superior segmental optic nerve hypoplasia: A review.
Wu JH, Lin CW, Liu CH, Weinreb RN, Welsbie DS
Surv Ophthalmol 2022 Sep-Oct;67(5):1467-1475. Epub 2022 Feb 18 doi: 10.1016/j.survophthal.2022.02.008. PMID: 35189184
Disorders of vision in multiple sclerosis.
Dhanapalaratnam R, Markoulli M, Krishnan AV
Clin Exp Optom 2022 Jan;105(1):3-12. Epub 2021 Aug 4 doi: 10.1080/08164622.2021.1947745. PMID: 34348598
Retinal Manifestations of Idiopathic Intracranial Hypertension.
Nichani P, Micieli JA
Ophthalmol Retina 2021 May;5(5):429-437. Epub 2020 Aug 26 doi: 10.1016/j.oret.2020.08.016. PMID: 32860958
Glial Cell-Derived Neurotrophic Factor Induces Enteric Neurogenesis and Improves Colon Structure and Function in Mouse Models of Hirschsprung Disease.
Soret R, Schneider S, Bernas G, Christophers B, Souchkova O, Charrier B, Righini-Grunder F, Aspirot A, Landry M, Kembel SW, Faure C, Heuckeroth RO, Pilon N
Gastroenterology 2020 Nov;159(5):1824-1838.e17. Epub 2020 Jul 17 doi: 10.1053/j.gastro.2020.07.018. PMID: 32687927
Cranial Pair 0: The Nervus Terminalis.
Peña-Melián Á, Cabello-de la Rosa JP, Gallardo-Alcañiz MJ, Vaamonde-Gamo J, Relea-Calatayud F, González-López L, Villanueva-Anguita P, Flores-Cuadrado A, Saiz-Sánchez D, Martínez-Marcos A
Anat Rec (Hoboken) 2019 Mar;302(3):394-404. Epub 2018 May 17 doi: 10.1002/ar.23826. PMID: 29663690

Recent systematic reviews

Isolated hypoganglionosis: systematic review of a rare intestinal innervation defect.
Dingemann J, Puri P
Pediatr Surg Int 2010 Nov;26(11):1111-5. doi: 10.1007/s00383-010-2693-3. PMID: 20721562
Skip segment Hirschsprung's disease: a systematic review.
O'Donnell AM, Puri P
Pediatr Surg Int 2010 Nov;26(11):1065-9. doi: 10.1007/s00383-010-2692-4. PMID: 20714729

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