U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Trichodysplasia

MedGen UID:
892721
•Concept ID:
C4025700
•
Disease or Syndrome
Synonyms: Generalised trichodysplasia; Generalized trichodysplasia
 
HPO: HP:0002552

Definition

Developmental dysplasia of the hair. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTrichodysplasia

Conditions with this feature

Dermo-odonto dysplasia
MedGen UID:
377602
•Concept ID:
C1852144
•
Disease or Syndrome
Dermo-odonto dysplasia belongs to the group of tricho-odonto-onychial dysplasia. It has signs of variable severity: dry and thin skin, dental anomalies, nail alteration and trichodysplasia.
See: Condition Record
Tricho-oculo-dermo-vertebral syndrome
MedGen UID:
355714
•Concept ID:
C1866427
•
Disease or Syndrome
See: Condition Record
Dermo-odonto dysplasia
Tricho-oculo-dermo-vertebral syndrome

Professional guidelines

PubMed

Trichodysplasia spinulosa: a comprehensive review of the disease and its treatment.
Curman P, Näsman A, Brauner H
J Eur Acad Dermatol Venereol 2021 May;35(5):1067-1076. Epub 2021 Jan 6 doi: 10.1111/jdv.17081. PMID: 33559344Free PMC Article
Serological Assessment of 18 Pathogens and Risk of AIDS-Associated Non-Hodgkin Lymphoma.
Halec G, Waterboer T, Brenner N, Butt J, Hardy WD, DʼSouza G, Wolinsky S, Macatangay BJ, Pawlita M, Detels R, Martínez-Maza O, Hussain SK
J Acquir Immune Defic Syndr 2019 Mar 1;80(3):e53-e63. doi: 10.1097/QAI.0000000000001916. PMID: 30531297Free PMC Article

Recent clinical studies

Etiology

Seroprevalence of Four Polyomaviruses Linked to Dermatological Diseases: New Findings and a Comprehensive Analysis.
Jeles K, Katona M, Csoma E
Viruses 2022 Oct 17;14(10) doi: 10.3390/v14102282. PMID: 36298837Free PMC Article
Complete resolution of trichodysplasia spinulosa in a pediatric renal transplant patient: Case report and literature review.
Coogle LP, Holland KE, Pan C, Van Why SK
Pediatr Transplant 2017 Mar;21(2) Epub 2016 Dec 25 doi: 10.1111/petr.12849. PMID: 28019062
Emerging infectious diseases with cutaneous manifestations: Viral and bacterial infections.
Nawas ZY, Tong Y, Kollipara R, Peranteau AJ, Woc-Colburn L, Yan AC, Lupi O, Tyring SK
J Am Acad Dermatol 2016 Jul;75(1):1-16. doi: 10.1016/j.jaad.2016.04.033. PMID: 27317512
Detection of novel polyomaviruses in fruit bats in Indonesia.
Kobayashi S, Sasaki M, Nakao R, Setiyono A, Handharyani E, Orba Y, Rahmadani I, Taha S, Adiani S, Subangkit M, Nakamura I, Kimura T, Sawa H
Arch Virol 2015 Apr;160(4):1075-82. Epub 2015 Feb 12 doi: 10.1007/s00705-015-2349-7. PMID: 25670407
Cutaneous viral infections in organ transplant patients.
Piaserico S, Sandini E, Peserico A, Alaibac M
G Ital Dermatol Venereol 2014 Aug;149(4):409-15. PMID: 25068228

Diagnosis

Trichodysplasia Spinulosa.
Khalili AA, Maciagowski E, Nguyen K, Watters KA
Sultan Qaboos Univ Med J 2024 Feb;24(1):131-134. Epub 2024 Feb 28 doi: 10.18295/squmj.5.2023.035. PMID: 38434466Free PMC Article
Recent developments in trichodysplasia spinulosa disease.
Narayanan D, Rady PL, Tyring SK
Transpl Infect Dis 2020 Dec;22(6):e13434. Epub 2020 Aug 16 doi: 10.1111/tid.13434. PMID: 32748541
The Biology and Clinical Features of Cutaneous Polyomaviruses.
Nguyen KD, Chamseddin BH, Cockerell CJ, Wang RC
J Invest Dermatol 2019 Feb;139(2):285-292. Epub 2018 Nov 22 doi: 10.1016/j.jid.2018.09.013. PMID: 30470393Free PMC Article
Trichodysplasia Spinulosa.
Rosenstein RK, Ko CJ, Colegio OR
Transplantation 2017 Oct;101(10):e314. doi: 10.1097/TP.0000000000001888. PMID: 28731909
Virus-associated Trichodysplasia spinulosa.
Tan BH, Busam KJ
Adv Anat Pathol 2011 Nov;18(6):450-3. doi: 10.1097/PAP.0b013e318234aad2. PMID: 21993271

Therapy

Trichodysplasia Spinulosa.
Khalili AA, Maciagowski E, Nguyen K, Watters KA
Sultan Qaboos Univ Med J 2024 Feb;24(1):131-134. Epub 2024 Feb 28 doi: 10.18295/squmj.5.2023.035. PMID: 38434466Free PMC Article
Trichodysplasia Spinulosa.
Rosenstein RK, Ko CJ, Colegio OR
Transplantation 2017 Oct;101(10):e314. doi: 10.1097/TP.0000000000001888. PMID: 28731909
Emerging infectious diseases with cutaneous manifestations: Viral and bacterial infections.
Nawas ZY, Tong Y, Kollipara R, Peranteau AJ, Woc-Colburn L, Yan AC, Lupi O, Tyring SK
J Am Acad Dermatol 2016 Jul;75(1):1-16. doi: 10.1016/j.jaad.2016.04.033. PMID: 27317512
Cutaneous viral infections in organ transplant patients.
Piaserico S, Sandini E, Peserico A, Alaibac M
G Ital Dermatol Venereol 2014 Aug;149(4):409-15. PMID: 25068228
Virus-associated Trichodysplasia spinulosa.
Tan BH, Busam KJ
Adv Anat Pathol 2011 Nov;18(6):450-3. doi: 10.1097/PAP.0b013e318234aad2. PMID: 21993271

Prognosis

Trichodysplasia spinulosa in the setting of colon cancer.
Thomas RS, Lear W, Bohlke A
Cutis 2018 Oct;102(4):262-264. PMID: 30489551
Detection of trichodysplasia spinulosa-associated polyomavirus in a fatal case of myocarditis in a seven-month-old girl.
Tsuzuki S, Fukumoto H, Mine S, Sato N, Mochizuki M, Hasegawa H, Sekizuka T, Kuroda M, Matsushita T, Katano H
Int J Clin Exp Pathol 2014;7(8):5308-12. Epub 2014 Jul 15 PMID: 25197415Free PMC Article
Cutaneous viral infections in organ transplant patients.
Piaserico S, Sandini E, Peserico A, Alaibac M
G Ital Dermatol Venereol 2014 Aug;149(4):409-15. PMID: 25068228
Genome analysis of the new human polyomaviruses.
Van Ghelue M, Khan MT, Ehlers B, Moens U
Rev Med Virol 2012 Nov;22(6):354-77. Epub 2012 Mar 28 doi: 10.1002/rmv.1711. PMID: 22461085
Two other cases of ANOTHER syndrome? Family report and update.
Pinheiro M, Penna FJ, Freire-Maia N
Clin Genet 1989 Apr;35(4):237-42. doi: 10.1111/j.1399-0004.1989.tb02937.x. PMID: 2653671

Clinical prediction guides

Seroprevalence of Four Polyomaviruses Linked to Dermatological Diseases: New Findings and a Comprehensive Analysis.
Jeles K, Katona M, Csoma E
Viruses 2022 Oct 17;14(10) doi: 10.3390/v14102282. PMID: 36298837Free PMC Article
Human polyomaviruses and cancer: an overview.
Prado JCM, Monezi TA, Amorim AT, Lino V, Paladino A, Boccardo E
Clinics (Sao Paulo) 2018 Oct 11;73(suppl 1):e558s. doi: 10.6061/clinics/2018/e558s. PMID: 30328951Free PMC Article
Cutaneous viral infections in organ transplant patients.
Piaserico S, Sandini E, Peserico A, Alaibac M
G Ital Dermatol Venereol 2014 Aug;149(4):409-15. PMID: 25068228
Serological cross-reactivity between human polyomaviruses.
Moens U, Van Ghelue M, Song X, Ehlers B
Rev Med Virol 2013 Jul;23(4):250-64. Epub 2013 May 6 doi: 10.1002/rmv.1747. PMID: 23650080
Virus-associated Trichodysplasia spinulosa.
Tan BH, Busam KJ
Adv Anat Pathol 2011 Nov;18(6):450-3. doi: 10.1097/PAP.0b013e318234aad2. PMID: 21993271

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...