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Diffuse C-Cell Hyperplasia

MedGen UID:
889728
•Concept ID:
C4048194
•
Disease or Syndrome

Definition

A non-neoplastic proliferation of morphologically bland C-cells with a diffuse growth pattern in the thyroid gland. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiffuse C-Cell Hyperplasia

Professional guidelines

PubMed

Comparison of calcium and pentagastrin tests for the diagnosis and follow-up of medullary thyroid cancer.
Colombo C, Verga U, Mian C, Ferrero S, Perrino M, Vicentini L, Dazzi D, Opocher G, Pelizzo MR, Beck-Peccoz P, Fugazzola L
J Clin Endocrinol Metab 2012 Mar;97(3):905-13. Epub 2011 Dec 14 doi: 10.1210/jc.2011-2033. PMID: 22170709

Recent clinical studies

Diagnosis

An Unusual Case of Medullary Thyroid Carcinoma and A Revision of Current Literature.
Cipri C, Vescini F, Torresan F, Pennelli G, Pelizzo MR, Triggiani V, Guastamacchia E, Grimaldi F
Endocr Metab Immune Disord Drug Targets 2019;19(2):226-229. doi: 10.2174/1871530319666181220165350. PMID: 30574858Free PMC Article
Occult medullary carcinoma of thyroid: an unusual clinical and pathologic presentation.
White IL, Vimadalal SD, Catz B, Van de Velde R, LaGanga T
Cancer 1981 Mar 15;47(6):1364-8. doi: 10.1002/1097-0142(19810315)47:6<1364::aid-cncr2820470621>3.0.co;2-l. PMID: 7226060

Therapy

Video-assisted central compartment lymphadenectomy in a patient with a positive RET oncogene: initial experience.
Miccoli P, Elisei R, Donatini G, Materazzi G, Berti P
Surg Endosc 2007 Jan;21(1):120-3. Epub 2006 Sep 6 doi: 10.1007/s00464-005-0642-3. PMID: 16960675

Prognosis

Occult medullary carcinoma of thyroid: an unusual clinical and pathologic presentation.
White IL, Vimadalal SD, Catz B, Van de Velde R, LaGanga T
Cancer 1981 Mar 15;47(6):1364-8. doi: 10.1002/1097-0142(19810315)47:6<1364::aid-cncr2820470621>3.0.co;2-l. PMID: 7226060

Supplemental Content

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    Practice guidelines

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