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Acute Uric Acid Nephropathy

MedGen UID:
888926
•Concept ID:
C0859034
•
Disease or Syndrome

Definition

Kidney damage resulting from uric acid precipitation within the renal tubules. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcute Uric Acid Nephropathy

Professional guidelines

PubMed

Impact of non-adherence on the safety and efficacy of uric acid-lowering therapies in the treatment of gout.
Hill-McManus D, Soto E, Marshall S, Lane S, Hughes D
Br J Clin Pharmacol 2018 Jan;84(1):142-152. Epub 2017 Oct 10 doi: 10.1111/bcp.13427. PMID: 28888218Free PMC Article
Allopurinol: intravenous use for prevention and treatment of hyperuricemia.
Smalley RV, Guaspari A, Haase-Statz S, Anderson SA, Cederberg D, Hohneker JA
J Clin Oncol 2000 Apr;18(8):1758-63. doi: 10.1200/JCO.2000.18.8.1758. PMID: 10764437
The treatment of gout and disorders of uric acid metabolism with allopurinol.
Ogryzlo MA, Urowitz MB, Weber HM, Houpt JB
Can Med Assoc J 1966 Nov 26;95(22):1120-7. PMID: 5923471Free PMC Article

Recent clinical studies

Etiology

Impact of non-adherence on the safety and efficacy of uric acid-lowering therapies in the treatment of gout.
Hill-McManus D, Soto E, Marshall S, Lane S, Hughes D
Br J Clin Pharmacol 2018 Jan;84(1):142-152. Epub 2017 Oct 10 doi: 10.1111/bcp.13427. PMID: 28888218Free PMC Article
Role of serum sodium in assessing hospital mortality in cancer patients with spontaneous tumour lysis syndrome inducing acute uric acid nephropathy.
Hsu HH, Chen YC, Tian YC, Chan YL, Kuo MC, Tang CC, Fang JT, Lee SY, Yang CW
Int J Clin Pract 2009 May;63(5):751-6. PMID: 19402210
Acute spontaneous tumor lysis presenting with hyperuricemic acute renal failure: clinical features and therapeutic approach.
Hsu HH, Chan YL, Huang CC
J Nephrol 2004 Jan-Feb;17(1):50-6. PMID: 15151259
Allopurinol: intravenous use for prevention and treatment of hyperuricemia.
Smalley RV, Guaspari A, Haase-Statz S, Anderson SA, Cederberg D, Hohneker JA
J Clin Oncol 2000 Apr;18(8):1758-63. doi: 10.1200/JCO.2000.18.8.1758. PMID: 10764437
A rapid method for the diagnosis of acute uric acid nephropathy.
Kelton J, Kelley WN, Holmes EW
Arch Intern Med 1978 Apr;138(4):612-5. PMID: 637642

Diagnosis

A Patient with Acute Kidney Injury Associated with Massive Proteinuria and Acute Hyperuricemia after Epileptic Seizures.
Tomomitsu Y, Asakawa S, Arai S, Nagura M, Ishizawa K, Yamazaki O, Tamura Y, Uchida S, Ohashi R, Shibata S, Fujigaki Y
Intern Med 2022 Nov 15;61(22):3401-3408. Epub 2022 Apr 23 doi: 10.2169/internalmedicine.8808-21. PMID: 35466163Free PMC Article
Acute spontaneous tumor lysis presenting with hyperuricemic acute renal failure: clinical features and therapeutic approach.
Hsu HH, Chan YL, Huang CC
J Nephrol 2004 Jan-Feb;17(1):50-6. PMID: 15151259
Acute uric acid nephropathy in pregnancy.
Alexopoulos E, Tampakoudis P, Bili H, Mantalenakis S
Obstet Gynecol 1992 Sep;80(3 Pt 2):488-9. PMID: 1495716
Acute uric acid nephropathy.
Conger JD
Med Clin North Am 1990 Jul;74(4):859-71. doi: 10.1016/s0025-7125(16)30522-3. PMID: 2195258
A rapid method for the diagnosis of acute uric acid nephropathy.
Kelton J, Kelley WN, Holmes EW
Arch Intern Med 1978 Apr;138(4):612-5. PMID: 637642

Therapy

Impact of non-adherence on the safety and efficacy of uric acid-lowering therapies in the treatment of gout.
Hill-McManus D, Soto E, Marshall S, Lane S, Hughes D
Br J Clin Pharmacol 2018 Jan;84(1):142-152. Epub 2017 Oct 10 doi: 10.1111/bcp.13427. PMID: 28888218Free PMC Article
Acute uric acid nephropathy.
Conger JD
Med Clin North Am 1990 Jul;74(4):859-71. doi: 10.1016/s0025-7125(16)30522-3. PMID: 2195258
A rapid method for the diagnosis of acute uric acid nephropathy.
Kelton J, Kelley WN, Holmes EW
Arch Intern Med 1978 Apr;138(4):612-5. PMID: 637642
The treatment of gout and disorders of uric acid metabolism with allopurinol.
Ogryzlo MA, Urowitz MB, Weber HM, Houpt JB
Can Med Assoc J 1966 Nov 26;95(22):1120-7. PMID: 5923471Free PMC Article
Allopurinal and acute uric acid nephropathy.
Watts RW, Watkins PJ, Matthias JQ, Gibbs DA
Br Med J 1966 Jan 22;1(5481):205-8. doi: 10.1136/bmj.1.5481.205. PMID: 5901729Free PMC Article

Prognosis

Role of serum sodium in assessing hospital mortality in cancer patients with spontaneous tumour lysis syndrome inducing acute uric acid nephropathy.
Hsu HH, Chen YC, Tian YC, Chan YL, Kuo MC, Tang CC, Fang JT, Lee SY, Yang CW
Int J Clin Pract 2009 May;63(5):751-6. PMID: 19402210
Acute spontaneous tumor lysis presenting with hyperuricemic acute renal failure: clinical features and therapeutic approach.
Hsu HH, Chan YL, Huang CC
J Nephrol 2004 Jan-Feb;17(1):50-6. PMID: 15151259
Acute spontaneous tumor lysis in anaplastic large T-cell lymphoma presenting with hyperuricemic acute renal failure.
Hsu HH, Huang CC
Int J Hematol 2004 Jan;79(1):48-51. doi: 10.1007/BF02983533. PMID: 14979478
An enormous abdominal mass associated with acute renal failure.
Hsu HH, Lin CL, Chen YC, Fang JT, Huang CC
Ren Fail 2001 Sep;23(5):721-5. doi: 10.1081/jdi-100107369. PMID: 11725919
Crystalluria: a neglected aspect of urinary sediment analysis.
Fogazzi GB
Nephrol Dial Transplant 1996 Feb;11(2):379-87. doi: 10.1093/oxfordjournals.ndt.a027276. PMID: 8671802

Clinical prediction guides

Role of serum sodium in assessing hospital mortality in cancer patients with spontaneous tumour lysis syndrome inducing acute uric acid nephropathy.
Hsu HH, Chen YC, Tian YC, Chan YL, Kuo MC, Tang CC, Fang JT, Lee SY, Yang CW
Int J Clin Pract 2009 May;63(5):751-6. PMID: 19402210
An enormous abdominal mass associated with acute renal failure.
Hsu HH, Lin CL, Chen YC, Fang JT, Huang CC
Ren Fail 2001 Sep;23(5):721-5. doi: 10.1081/jdi-100107369. PMID: 11725919
Renal uric acid clearance in human neonates.
Stapleton FB
J Pediatr 1983 Aug;103(2):290-4. doi: 10.1016/s0022-3476(83)80369-2. PMID: 6875727
Ticrynafen-induced acute renal failure.
Powers D, Vaziri ND, Muhalwas K, Hubbell FA, Weber M, Mirahmadi K
Clin Toxicol 1981 Apr;18(4):425-30. doi: 10.3109/15563658108990266. PMID: 7237970

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