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Child Development Disorders, Pervasive

MedGen UID:
887
Concept ID:
C0008074
Mental or Behavioral Dysfunction
Synonym: Pervasive Child Development Disorders

Definition

Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements. [from MeSH]

Professional guidelines

PubMed

Rogers JP, Oldham MA, Fricchione G, Northoff G, Ellen Wilson J, Mann SC, Francis A, Wieck A, Elizabeth Wachtel L, Lewis G, Grover S, Hirjak D, Ahuja N, Zandi MS, Young AH, Fone K, Andrews S, Kessler D, Saifee T, Gee S, Baldwin DS, David AS
J Psychopharmacol 2023 Apr;37(4):327-369. Epub 2023 Apr 11 doi: 10.1177/02698811231158232. PMID: 37039129Free PMC Article
Styles M, Alsharshani D, Samara M, Alsharshani M, Khattab A, Qoronfleh MW, Al-Dewik NI
Front Biosci (Landmark Ed) 2020 Jun 1;25(9):1682-1717. doi: 10.2741/4873. PMID: 32472753
Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089

Recent clinical studies

Etiology

Bourgeron T
Nat Rev Neurosci 2015 Sep;16(9):551-63. doi: 10.1038/nrn3992. PMID: 26289574
Richa S, Fahed M, Khoury E, Mishara B
Arch Suicide Res 2014;18(4):327-39. doi: 10.1080/13811118.2013.824834. PMID: 24713024
Kawicka A, Regulska-Ilow B
Rocz Panstw Zakl Hig 2013;64(1):1-12. PMID: 23789306
Pfeiffer BA, Koenig K, Kinnealey M, Sheppard M, Henderson L
Am J Occup Ther 2011 Jan-Feb;65(1):76-85. doi: 10.5014/ajot.2011.09205. PMID: 21309374Free PMC Article
Faras H, Al Ateeqi N, Tidmarsh L
Ann Saudi Med 2010 Jul-Aug;30(4):295-300. doi: 10.4103/0256-4947.65261. PMID: 20622347Free PMC Article

Diagnosis

Bourgeron T
Nat Rev Neurosci 2015 Sep;16(9):551-63. doi: 10.1038/nrn3992. PMID: 26289574
Bhat S, Acharya UR, Adeli H, Bairy GM, Adeli A
Rev Neurosci 2014;25(6):841-50. doi: 10.1515/revneuro-2014-0056. PMID: 25222596
Mottron L, Dawson M
Handb Clin Neurol 2013;111:263-71. doi: 10.1016/B978-0-444-52891-9.00029-4. PMID: 23622174
Manning-Courtney P, Murray D, Currans K, Johnson H, Bing N, Kroeger-Geoppinger K, Sorensen R, Bass J, Reinhold J, Johnson A, Messerschmidt T
Curr Probl Pediatr Adolesc Health Care 2013 Jan;43(1):2-11. doi: 10.1016/j.cppeds.2012.08.001. PMID: 23332397
O'Haire ME
J Autism Dev Disord 2013 Jul;43(7):1606-22. doi: 10.1007/s10803-012-1707-5. PMID: 23124442

Therapy

Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089
Case-Smith J, Weaver LL, Fristad MA
Autism 2015 Feb;19(2):133-48. Epub 2014 Jan 29 doi: 10.1177/1362361313517762. PMID: 24477447
Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW
Proc Natl Acad Sci U S A 2014 Oct 28;111(43):15550-5. Epub 2014 Oct 13 doi: 10.1073/pnas.1416940111. PMID: 25313065Free PMC Article
Geretsegger M, Elefant C, Mössler KA, Gold C
Cochrane Database Syst Rev 2014 Jun 17;2014(6):CD004381. doi: 10.1002/14651858.CD004381.pub3. PMID: 24936966Free PMC Article
Pfeiffer BA, Koenig K, Kinnealey M, Sheppard M, Henderson L
Am J Occup Ther 2011 Jan-Feb;65(1):76-85. doi: 10.5014/ajot.2011.09205. PMID: 21309374Free PMC Article

Prognosis

Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089
Volkmar F, Siegel M, Woodbury-Smith M, King B, McCracken J, State M; American Academy of Child and Adolescent Psychiatry (AACAP) Committee on Quality Issues (CQI)
J Am Acad Child Adolesc Psychiatry 2014 Feb;53(2):237-57. doi: 10.1016/j.jaac.2013.10.013. PMID: 24472258
Robins DL, Casagrande K, Barton M, Chen CM, Dumont-Mathieu T, Fein D
Pediatrics 2014 Jan;133(1):37-45. Epub 2013 Dec 23 doi: 10.1542/peds.2013-1813. PMID: 24366990Free PMC Article
Kawicka A, Regulska-Ilow B
Rocz Panstw Zakl Hig 2013;64(1):1-12. PMID: 23789306
Christensen J, Grønborg TK, Sørensen MJ, Schendel D, Parner ET, Pedersen LH, Vestergaard M
JAMA 2013 Apr 24;309(16):1696-703. doi: 10.1001/jama.2013.2270. PMID: 23613074Free PMC Article

Clinical prediction guides

Shubrata KS, Sinha S, Seshadri SP, Girimaji S, Subbakrishna DK, Srinath S
J Child Neurol 2015 Mar;30(4):476-82. Epub 2014 Jul 17 doi: 10.1177/0883073814540521. PMID: 25038126
Alabdali A, Al-Ayadhi L, El-Ansary A
J Neuroinflammation 2014 Jan 8;11:4. doi: 10.1186/1742-2094-11-4. PMID: 24400970Free PMC Article
Dworzynski K, Ronald A, Bolton P, Happé F
J Am Acad Child Adolesc Psychiatry 2012 Aug;51(8):788-97. Epub 2012 Jun 26 doi: 10.1016/j.jaac.2012.05.018. PMID: 22840550
Pfeiffer BA, Koenig K, Kinnealey M, Sheppard M, Henderson L
Am J Occup Ther 2011 Jan-Feb;65(1):76-85. doi: 10.5014/ajot.2011.09205. PMID: 21309374Free PMC Article
Baird G, Charman T, Cox A, Baron-Cohen S, Swettenham J, Wheelwright S, Drew A
Arch Dis Child 2001 Jun;84(6):468-75. doi: 10.1136/adc.84.6.468. PMID: 11369559Free PMC Article

Recent systematic reviews

Case-Smith J, Weaver LL, Fristad MA
Autism 2015 Feb;19(2):133-48. Epub 2014 Jan 29 doi: 10.1177/1362361313517762. PMID: 24477447
Geretsegger M, Elefant C, Mössler KA, Gold C
Cochrane Database Syst Rev 2014 Jun 17;2014(6):CD004381. doi: 10.1002/14651858.CD004381.pub3. PMID: 24936966Free PMC Article
Marí-Bauset S, Zazpe I, Mari-Sanchis A, Llopis-González A, Morales-Suárez-Varela M
J Child Neurol 2014 Nov;29(11):1554-61. Epub 2013 Oct 4 doi: 10.1177/0883073813498821. PMID: 24097852
Fernandes FD, Amato CA
Codas 2013;25(3):289-96. doi: 10.1590/s2317-17822013000300016. PMID: 24408342
Elsabbagh M, Divan G, Koh YJ, Kim YS, Kauchali S, Marcín C, Montiel-Nava C, Patel V, Paula CS, Wang C, Yasamy MT, Fombonne E
Autism Res 2012 Jun;5(3):160-79. Epub 2012 Apr 11 doi: 10.1002/aur.239. PMID: 22495912Free PMC Article

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