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Malignant Pancreatic Glucagonoma

MedGen UID:
87209
Concept ID:
C0334282
Neoplastic Process
Synonyms: Alpha cell tumor, malignant; Glucagonoma, malignant; Malignant alpha cell neoplasm of pancreas; Malignant alpha cell tumor; Malignant Glucagonoma; Malignant glucagonoma; Malignant glucagonoma of pancreas; Pancreatic Alpha Cell Carcinoma
SNOMED CT: Glucagonoma, malignant (66515009); Alpha cell tumor, malignant (66515009); Malignant alpha cell tumor (66515009); Malignant glucagonoma (66515009); Malignant alpha cell neoplasm of pancreas (1187521002); Malignant glucagonoma of pancreas (1187521002)

Definition

A glucagon-producing neuroendocrine tumor arising from the alpha cells of the pancreas. It may be associated with necrolytic erythema migrans, diarrhea, diabetes, glossitis, weight loss, malabsorption, and anemia. It displays vascular invasion and metastasizes to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Pancreatic Glucagonoma

Professional guidelines

PubMed

Popoviciu MS, Paduraru L, Nutas RM, Ujoc AM, Yahya G, Metwally K, Cavalu S
Int J Mol Sci 2023 Aug 11;24(16) doi: 10.3390/ijms241612676. PMID: 37628857Free PMC Article
John AM, Schwartz RA
J Eur Acad Dermatol Venereol 2016 Dec;30(12):2016-2022. Epub 2016 Jul 16 doi: 10.1111/jdv.13752. PMID: 27422767
Ito T, Igarashi H, Jensen RT
Best Pract Res Clin Gastroenterol 2012 Dec;26(6):737-53. doi: 10.1016/j.bpg.2012.12.003. PMID: 23582916Free PMC Article

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