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Spina bifida occulta at L5

MedGen UID:
870848
Concept ID:
C4025308
Congenital Abnormality
HPO: HP:0004601

Definition

The closed form of spina bifida with incomplete closure of the vertebra L5 with intact overlying skin. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSpina bifida occulta at L5

Conditions with this feature

Acropectorovertebral dysplasia
MedGen UID:
400262
Concept ID:
C1863307
Disease or Syndrome
Acropectorovertebral dysgenesis, or F syndrome, is an autosomal dominant skeletal dysplasia characterized by carpal and tarsal synostoses, syndactyly between the first and second fingers, hypodactyly and polydactyly of feet, and abnormalities of the sternum and spine (summary by Thiele et al., 2004).

Professional guidelines

PubMed

Kuroshima K, Miyazaki S, Hiranaka Y, Ryu M, Inoue S, Yurube T, Kakutani K, Tadokoro K
Am J Sports Med 2024 Sep;52(11):2866-2873. Epub 2024 Sep 2 doi: 10.1177/03635465241270293. PMID: 39221535
Tatsumura M, Gamada H, Okuwaki S, Eto F, Nagashima K, Ogawa T, Mammoto T, Hirano A, Koda M, Yamazaki M
BMC Musculoskelet Disord 2021 Jan 13;22(1):75. doi: 10.1186/s12891-020-03940-9. PMID: 33441118Free PMC Article
Cakiroglu B, Tas T, Eyyupoglu SE, Hazar AI, Can Balcı MB, Nas Y, Yilmazer F, Aksoy SH
Arch Ital Urol Androl 2014 Dec 30;86(4):270-3. doi: 10.4081/aiua.2014.4.270. PMID: 25641449

Recent clinical studies

Etiology

Mehrotra A, Pandey SD, Singh S, Kanjilal S, Gajbhiye S, Dikshit P, Kumar A, Verma PK, Maurya VP, Bhaisora KS, Das KK, Srivastava AK, Jaiswal AK, Kumar R
Neurol India 2024 Jul 1;72(4):742-746. Epub 2024 Aug 31 doi: 10.4103/neurol-india.Neurol-India-D-23-00245. PMID: 39216027
Gamada H, Tatsumura M, Okuwaki S, Asai R, Funayama T, Yamazaki M
BMC Musculoskelet Disord 2024 Jan 12;25(1):55. doi: 10.1186/s12891-024-07190-x. PMID: 38216892Free PMC Article
Illeez OG, Ulger FEB, Aktas I
Acta Orthop Belg 2022 Jun;88(2):275-283. doi: 10.52628/88.2.8528. PMID: 36001833
Li W, Xiong Z, Dong C, Song J, Zhang L, Zhou J, Wang Y, Yi P, Yang F, Tang X, Tan M
J Orthop Surg Res 2021 Feb 22;16(1):151. doi: 10.1186/s13018-021-02285-w. PMID: 33618758Free PMC Article
Shin SH, Im YJ, Lee MJ, Lee YS, Choi EK, Han SW
Int J Urol 2013 Aug;20(8):831-5. Epub 2013 Jan 8 doi: 10.1111/iju.12054. PMID: 23294087

Diagnosis

Mehrotra A, Pandey SD, Singh S, Kanjilal S, Gajbhiye S, Dikshit P, Kumar A, Verma PK, Maurya VP, Bhaisora KS, Das KK, Srivastava AK, Jaiswal AK, Kumar R
Neurol India 2024 Jul 1;72(4):742-746. Epub 2024 Aug 31 doi: 10.4103/neurol-india.Neurol-India-D-23-00245. PMID: 39216027
Asai R, Tatsumura M, Gamada H, Okuwaki S, Eto F, Nagashima K, Takeuchi Y, Funayama T, Mammoto T, Hirano A, Yamazaki M
BMC Musculoskelet Disord 2023 Jul 8;24(1):558. doi: 10.1186/s12891-023-06679-1. PMID: 37422627Free PMC Article
Tsukagoshi Y, Kamegaya M, Tatsumura M, Tomaru Y, Kamada H, Morita M, Saisu T, Nomura S, Ikezawa Y, Yamazaki M
Eur Spine J 2020 Oct;29(10):2465-2469. Epub 2020 Jul 31 doi: 10.1007/s00586-020-06553-x. PMID: 32737580
Sakai T, Goda Y, Tezuka F, Takata Y, Higashino K, Sato M, Mase Y, Nagamachi A, Sairyo K
Eur Spine J 2016 Feb;25(2):602-6. Epub 2015 May 26 doi: 10.1007/s00586-015-4029-4. PMID: 26006706
Shin SH, Im YJ, Lee MJ, Lee YS, Choi EK, Han SW
Int J Urol 2013 Aug;20(8):831-5. Epub 2013 Jan 8 doi: 10.1111/iju.12054. PMID: 23294087

Therapy

Suryadevara R, Lieber BA, Garcia E, Sood S, Haridas A, Ham S
Childs Nerv Syst 2018 Apr;34(4):787-789. Epub 2018 Jan 2 doi: 10.1007/s00381-017-3689-2. PMID: 29294141
Wang T, Fielding LC, Parikh A, Kothari M, Alamin T
Spine J 2015 Dec 1;15(12):2544-51. Epub 2015 Sep 4 doi: 10.1016/j.spinee.2015.08.058. PMID: 26343242
Shin SH, Im YJ, Lee MJ, Lee YS, Choi EK, Han SW
Int J Urol 2013 Aug;20(8):831-5. Epub 2013 Jan 8 doi: 10.1111/iju.12054. PMID: 23294087
Verhoef M, Lurvink M, Barf HA, Post MW, van Asbeck FW, Gooskens RH, Prevo AJ
Spinal Cord 2005 Jun;43(6):331-40. doi: 10.1038/sj.sc.3101705. PMID: 15685262
Linn RM, Ford LT
Spine (Phila Pa 1976) 1994 Apr 1;19(7):852-4. doi: 10.1097/00007632-199404000-00024. PMID: 8202809

Prognosis

Kuroshima K, Miyazaki S, Hiranaka Y, Ryu M, Inoue S, Yurube T, Kakutani K, Tadokoro K
Am J Sports Med 2024 Sep;52(11):2866-2873. Epub 2024 Sep 2 doi: 10.1177/03635465241270293. PMID: 39221535
Doi M, Sakurai Y, Sakamaki D, Tanaka S, Katori N, Uezono S
BMC Anesthesiol 2023 Apr 24;23(1):134. doi: 10.1186/s12871-023-02101-4. PMID: 37095440Free PMC Article
Cakiroglu B, Tas T, Eyyupoglu SE, Hazar AI, Can Balcı MB, Nas Y, Yilmazer F, Aksoy SH
Arch Ital Urol Androl 2014 Dec 30;86(4):270-3. doi: 10.4081/aiua.2014.4.270. PMID: 25641449
Shin SH, Im YJ, Lee MJ, Lee YS, Choi EK, Han SW
Int J Urol 2013 Aug;20(8):831-5. Epub 2013 Jan 8 doi: 10.1111/iju.12054. PMID: 23294087
Nejat F, Radmanesh F, Ansari S, Tajik P, Kajbafzadeh A, El Khashab M
J Neurosurg Pediatr 2008 Feb;1(2):114-7. doi: 10.3171/PED/2008/1/2/114. PMID: 18352778

Clinical prediction guides

Mehrotra A, Pandey SD, Singh S, Kanjilal S, Gajbhiye S, Dikshit P, Kumar A, Verma PK, Maurya VP, Bhaisora KS, Das KK, Srivastava AK, Jaiswal AK, Kumar R
Neurol India 2024 Jul 1;72(4):742-746. Epub 2024 Aug 31 doi: 10.4103/neurol-india.Neurol-India-D-23-00245. PMID: 39216027
Illeez OG, Ulger FEB, Aktas I
Acta Orthop Belg 2022 Jun;88(2):275-283. doi: 10.52628/88.2.8528. PMID: 36001833
Cakiroglu B, Tas T, Eyyupoglu SE, Hazar AI, Can Balcı MB, Nas Y, Yilmazer F, Aksoy SH
Arch Ital Urol Androl 2014 Dec 30;86(4):270-3. doi: 10.4081/aiua.2014.4.270. PMID: 25641449
Shin SH, Im YJ, Lee MJ, Lee YS, Choi EK, Han SW
Int J Urol 2013 Aug;20(8):831-5. Epub 2013 Jan 8 doi: 10.1111/iju.12054. PMID: 23294087
Nejat F, Radmanesh F, Ansari S, Tajik P, Kajbafzadeh A, El Khashab M
J Neurosurg Pediatr 2008 Feb;1(2):114-7. doi: 10.3171/PED/2008/1/2/114. PMID: 18352778

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