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Abnormal cervical myelogram

MedGen UID:
870681
Concept ID:
C4025135
Anatomical Abnormality
HPO: HP:0005788

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal cervical myelogram

Conditions with this feature

Primary basilar invagination
MedGen UID:
400018
Concept ID:
C1862299
Disease or Syndrome
Primary basilar impression of the skull is a developmental defect of the cranium in which there is invagination of the foramen magnum upward into the posterior cranial fossa. Basilar impression is often associated with other malformations of the notochord and craniovertebral junction, such as occipitalization of the atlas, Klippel-Feil anomaly (see 118100), Chiari type I malformation (118420), and syringomyelia (186700) (Paradis and Sax, 1972; Bhangoo and Crockard, 1999). Secondary basilar impression occurs as a result of generalized skeletal diseases, including hyperparathyroidism (see 145000), Paget disease (see 167250), and osteogenesis imperfecta (see, e.g., 166200). Platybasia refers to a skull base with an abnormally obtuse angle between the planes of the clivus and the anterior fossa. Platybasia may occur in basilar impression, but it is not of medical significance on its own (Bhangoo and Crockard, 1999). Historically, basilar impression was defined radiologically by numerous parameters, including the lines defined by Chamberlain (1939), McGregor (1948), and Fischgold and Metzger (1952), and the angle defined by Bull et al. (1955).

Professional guidelines

PubMed

Epstein N
Spine J 2002 Nov-Dec;2(6):436-49. doi: 10.1016/s1529-9430(02)00394-7. PMID: 14589269
Emery SE
J Am Acad Orthop Surg 2001 Nov-Dec;9(6):376-88. doi: 10.5435/00124635-200111000-00003. PMID: 11767723
Vanichkachorn JS, Vaccaro AR
J Am Acad Orthop Surg 2000 May-Jun;8(3):159-69. doi: 10.5435/00124635-200005000-00003. PMID: 10874223

Recent clinical studies

Etiology

Heiss JD, Snyder K, Peterson MM, Patronas NJ, Butman JA, Smith RK, Devroom HL, Sansur CA, Eskioglu E, Kammerer WA, Oldfield EH
J Neurosurg Spine 2012 Nov;17(5):367-80. Epub 2012 Sep 7 doi: 10.3171/2012.8.SPINE111059. PMID: 22958075Free PMC Article
Gordon N
Dev Med Child Neurol 2009 Dec;51(12):932-5. doi: 10.1111/j.1469-8749.2009.03514.x. PMID: 19909307
Epstein N
Spine J 2002 Nov-Dec;2(6):436-49. doi: 10.1016/s1529-9430(02)00394-7. PMID: 14589269
Emery SE
J Am Acad Orthop Surg 2001 Nov-Dec;9(6):376-88. doi: 10.5435/00124635-200111000-00003. PMID: 11767723
Pang D, Dias MS
Neurosurgery 1993 Sep;33(3):363-72; discussion 372-3. doi: 10.1227/00006123-199309000-00003. PMID: 8413865

Diagnosis

Gordon N
Dev Med Child Neurol 2009 Dec;51(12):932-5. doi: 10.1111/j.1469-8749.2009.03514.x. PMID: 19909307
Schievink WI
Cephalalgia 2008 Dec;28(12):1345-56. doi: 10.1111/j.1468-2982.2008.01776.x. PMID: 19037970
Emery SE
J Am Acad Orthop Surg 2001 Nov-Dec;9(6):376-88. doi: 10.5435/00124635-200111000-00003. PMID: 11767723
Maiuri F, Corriero G, Giamundo A, Donati P, Gambardella A
Neurochirurgia (Stuttg) 1988 Jan;31(1):29-31. doi: 10.1055/s-2008-1053895. PMID: 3347335
Giménez-Roldán S, Benito C, Mateo D
J Neurol Sci 1978 Mar;36(1):135-46. doi: 10.1016/0022-510x(78)90167-3. PMID: 650252

Therapy

Taylor MN, Tambi S, Almeida ND, Housley SB, Reynolds RM
World Neurosurg 2022 Aug;164:156-158. Epub 2022 May 4 doi: 10.1016/j.wneu.2022.04.117. PMID: 35525438
Heiss JD, Snyder K, Peterson MM, Patronas NJ, Butman JA, Smith RK, Devroom HL, Sansur CA, Eskioglu E, Kammerer WA, Oldfield EH
J Neurosurg Spine 2012 Nov;17(5):367-80. Epub 2012 Sep 7 doi: 10.3171/2012.8.SPINE111059. PMID: 22958075Free PMC Article
Chin KR, Eiszner JR, Huang JL, Huang JI, Roh JS, Bohlman HH
J Spinal Disord Tech 2008 Jul;21(5):334-7. doi: 10.1097/BSD.0b013e3181506780. PMID: 18600143
Epstein N
Spine J 2002 Nov-Dec;2(6):436-49. doi: 10.1016/s1529-9430(02)00394-7. PMID: 14589269
Godwin-Austen RB, Howell DA, Worthington B
Brain 1975 Dec;98(4):557-68. doi: 10.1093/brain/98.4.557. PMID: 1218367

Prognosis

Emery SE
J Am Acad Orthop Surg 2001 Nov-Dec;9(6):376-88. doi: 10.5435/00124635-200111000-00003. PMID: 11767723
Vanichkachorn JS, Vaccaro AR
J Am Acad Orthop Surg 2000 May-Jun;8(3):159-69. doi: 10.5435/00124635-200005000-00003. PMID: 10874223
Wilmink JT
Eur Radiol 1999;9(7):1259-66. doi: 10.1007/s003300050832. PMID: 10460358
Naderi S, Ozgen S, Pamir MN, Ozek MM, Erzen C
Neurosurgery 1998 Jul;43(1):43-9; discussion 49-50. doi: 10.1097/00006123-199807000-00028. PMID: 9657187
Pang D, Dias MS
Neurosurgery 1993 Sep;33(3):363-72; discussion 372-3. doi: 10.1227/00006123-199309000-00003. PMID: 8413865

Clinical prediction guides

Laohaprasitiporn P, Wongtrakul S, Vathana T, Limthongthang R, Songcharoen P
J Hand Surg Asian Pac Vol 2018 Sep;23(3):360-363. doi: 10.1142/S2424835518500376. PMID: 30282542
Kim WJ, Shin HY, Kim YC, Moon JY
J Neurosurg Anesthesiol 2016 Apr;28(2):147-52. doi: 10.1097/ANA.0000000000000259. PMID: 26649768
Pang D
Neurosurgery 1992 Sep;31(3):481-500. doi: 10.1227/00006123-199209000-00011. PMID: 1407429
Modic MT, Weinstein MA, Pavlicek W, Boumphrey F, Starnes D, Duchesneau PM
AJR Am J Roentgenol 1983 Dec;141(6):1129-36. doi: 10.2214/ajr.141.6.1129. PMID: 6606307
Godwin-Austen RB, Howell DA, Worthington B
Brain 1975 Dec;98(4):557-68. doi: 10.1093/brain/98.4.557. PMID: 1218367

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