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Synostosis involving bones of the lower limbs

MedGen UID:
870145
•Concept ID:
C4024577
•
Anatomical Abnormality
Synonym: Fusion involving the bones of the lower limbs
 
HPO: HP:0009138

Definition

An abnormal union between bones or parts of bones lower limbs. [from HPO]

Recent clinical studies

Etiology

The feet in Pfeiffer's syndrome.
Anderson PJ, Hall CM, Evans RD, Jones BM, Hayward RD
J Craniofac Surg 1998 Jan;9(1):83-7. doi: 10.1097/00001665-199801000-00018. PMID: 9558574
FFU complex: an analysis of 491 cases.
Lenz W, Zygulska M, Horst J
Hum Genet 1993 May;91(4):347-56. doi: 10.1007/BF00217355. PMID: 8500790
Brachy/ectrodactyly and absence or hypoplasia of the fibula: an autosomal dominant condition with low penetrance and variable expressivity.
Genuardi M, Zollino M, Bellussi A, Fuhrmann W, Neri G
Clin Genet 1990 Nov;38(5):321-6. doi: 10.1111/j.1399-0004.1990.tb03589.x. PMID: 2178076

Diagnosis

A case report on fibular aplasia, tibial campomelia, oligosyndactyly syndrome variant in a male infant.
Hashmi HM, Shamim N, Kumar V, Mirza A, Kirmani S, Irfan B, Hasan H
J Pak Med Assoc 2022 May;72(5):975-977. doi: 10.47391/JPMA.3793. PMID: 35713069
Management of Complex Tarsal Coalition in Children.
Li S, Myerson MS
Foot Ankle Clin 2021 Dec;26(4):941-954. Epub 2021 Aug 30 doi: 10.1016/j.fcl.2021.07.012. PMID: 34752245
The feet in Pfeiffer's syndrome.
Anderson PJ, Hall CM, Evans RD, Jones BM, Hayward RD
J Craniofac Surg 1998 Jan;9(1):83-7. doi: 10.1097/00001665-199801000-00018. PMID: 9558574
Focal dermal hypoplasia (Goltz syndrome): report of two cases with minor cutaneous and extracutaneous manifestations.
Pujol RM, Casanova JM, Pérez M, Matias-Guiu X, Planagumà M, de Moragas JM
Pediatr Dermatol 1992 Jun;9(2):112-6. doi: 10.1111/j.1525-1470.1992.tb01225.x. PMID: 1318543

Prognosis

The feet in Pfeiffer's syndrome.
Anderson PJ, Hall CM, Evans RD, Jones BM, Hayward RD
J Craniofac Surg 1998 Jan;9(1):83-7. doi: 10.1097/00001665-199801000-00018. PMID: 9558574

Clinical prediction guides

The feet in Pfeiffer's syndrome.
Anderson PJ, Hall CM, Evans RD, Jones BM, Hayward RD
J Craniofac Surg 1998 Jan;9(1):83-7. doi: 10.1097/00001665-199801000-00018. PMID: 9558574

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