U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Synostosis of thumb phalanx

MedGen UID:
869832
•Concept ID:
C4024263
•
Anatomical Abnormality
Synonym: Fusion of thumb bone
 
HPO: HP:0009635

Definition

Fusion of a phalanx of the thumb with another bone. [from HPO]

Professional guidelines

PubMed

Central Coalition Osteotomy of Phalangeal Synostoses in the Management of the Type III Apert Hand.
Theman TA, Upton J, Taghinia AH, Firriolo JM, Nuzzi LC, Labow BI
J Hand Surg Am 2018 Nov;43(11):1042.e1-1042.e8. Epub 2018 Jun 8 doi: 10.1016/j.jhsa.2018.03.050. PMID: 29891270

Recent clinical studies

Etiology

Open-wedge osteotomy for thumb radial angulation in Apert syndrome using a bone-graft substitute.
Shintani K, Kazuki K, Nakagawa K, Hosomi R, Kitano T
J Pediatr Orthop B 2022 Sep 1;31(5):500-504. Epub 2021 Dec 2 doi: 10.1097/BPB.0000000000000938. PMID: 35438886
Distraction Lengthening of the Apert Thumb.
Upton J, McNamara CT, Ali B, Nuzzi LC, Taghinia AH, Labow BI
Plast Reconstr Surg 2022 Apr 1;149(4):691e-699e. doi: 10.1097/PRS.0000000000008929. PMID: 35157629
Central Coalition Osteotomy of Phalangeal Synostoses in the Management of the Type III Apert Hand.
Theman TA, Upton J, Taghinia AH, Firriolo JM, Nuzzi LC, Labow BI
J Hand Surg Am 2018 Nov;43(11):1042.e1-1042.e8. Epub 2018 Jun 8 doi: 10.1016/j.jhsa.2018.03.050. PMID: 29891270
Application of C-Shaped Osteotomy and Distraction Osteogenesis for Correction of Radial Angulation Deformities of the Hand in Children With Apert Syndrome: Review of 10 Years of Experience.
Vargel I, Calis M, Cavusoglu T, Ekin O, Oznur A
Ann Plast Surg 2015 Nov;75(5):513-7. doi: 10.1097/SAP.0000000000000353. PMID: 25275478
The anatomy and management of the thumb in Apert syndrome.
Fereshetian S, Upton J
Clin Plast Surg 1991 Apr;18(2):365-80. PMID: 2065494

Diagnosis

Triphalangeal thump, thumb duplication, and syndactyly: The first case report in the literature.
Swed S, Nashwan AJ, Saleh HH, Chawa Y, Baria A, Etr A
Medicine (Baltimore) 2022 Oct 21;101(42):e31237. doi: 10.1097/MD.0000000000031237. PMID: 36281136Free PMC Article
Hypothesis: Symbrachydactyly.
Holmes LB, Nasri HZ
Am J Med Genet A 2022 Nov;188(11):3236-3241. Epub 2022 Sep 8 doi: 10.1002/ajmg.a.62941. PMID: 36073773
Craniosynostosis: Acrocephalosyndactyly (Apert Syndrome) Diagnosed in a Newborn.
Stomnaroska O, Danilovski D, Ivanovska S
Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2017 Dec 1;38(3):153-155. doi: 10.2478/prilozi-2018-0016. PMID: 29668474
Apert syndrome - clinical case.
Siminel MA, NeamŢu CO, DiŢescu D, ForŢofoiu MC, Comănescu AC, Novac MB, NeamŢu SD, Gluhovschi A
Rom J Morphol Embryol 2017;58(1):277-280. PMID: 28523332
Are triphalangeal thumb-polysyndactyly syndrome (TPTPS) and tibial hemimelia-polysyndactyly-triphalangeal thumb syndrome (THPTTS) identical? A father with TPTPS and his daughter with THPTTS in a Thai family.
Kantaputra PN, Chalidapong P
Am J Med Genet 2000 Jul 17;93(2):126-31. doi: 10.1002/1096-8628(20000717)93:2<126::aid-ajmg9>3.0.co;2-s. PMID: 10869115

Prognosis

Craniosynostosis: Acrocephalosyndactyly (Apert Syndrome) Diagnosed in a Newborn.
Stomnaroska O, Danilovski D, Ivanovska S
Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2017 Dec 1;38(3):153-155. doi: 10.2478/prilozi-2018-0016. PMID: 29668474
Application of C-Shaped Osteotomy and Distraction Osteogenesis for Correction of Radial Angulation Deformities of the Hand in Children With Apert Syndrome: Review of 10 Years of Experience.
Vargel I, Calis M, Cavusoglu T, Ekin O, Oznur A
Ann Plast Surg 2015 Nov;75(5):513-7. doi: 10.1097/SAP.0000000000000353. PMID: 25275478
On-top plasty using a free metacarpal head graft for lengthening of proximal phalanx in symbrachydactyly--a case report.
Iba K, Wada T, Yamashita T
Hand Surg 2013;18(2):273-5. doi: 10.1142/S0218810413720192. PMID: 24164137
Thumb radial angulation correction without phalangeal osteotomy in Apert's syndrome.
Dao KD, Shin AY, Kelley S, Wood VE
J Hand Surg Am 2002 Jan;27(1):125-32. doi: 10.1053/jhsu.2002.27772. PMID: 11810626
Type 3 Pfeiffer syndrome with normal thumbs.
Kerr NC, Wilroy RS Jr, Kaufman RA
Am J Med Genet 1996 Dec 11;66(2):138-43. doi: 10.1002/(SICI)1096-8628(19961211)66:2<138::AID-AJMG3>3.0.CO;2-N. PMID: 8958319

Clinical prediction guides

Thumb and first webspace reconstruction in nonsyndromic congenital mitten hand with symbrachydactyly.
Shen XF, Yin F, Gasteratos K, Wang J, Chim H, Rui YJ
J Plast Reconstr Aesthet Surg 2022 Jun;75(6):1902-1906. Epub 2021 Dec 6 doi: 10.1016/j.bjps.2021.11.113. PMID: 34972652
Central Coalition Osteotomy of Phalangeal Synostoses in the Management of the Type III Apert Hand.
Theman TA, Upton J, Taghinia AH, Firriolo JM, Nuzzi LC, Labow BI
J Hand Surg Am 2018 Nov;43(11):1042.e1-1042.e8. Epub 2018 Jun 8 doi: 10.1016/j.jhsa.2018.03.050. PMID: 29891270
Craniosynostosis: Acrocephalosyndactyly (Apert Syndrome) Diagnosed in a Newborn.
Stomnaroska O, Danilovski D, Ivanovska S
Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2017 Dec 1;38(3):153-155. doi: 10.2478/prilozi-2018-0016. PMID: 29668474
The anatomy and management of the thumb in Apert syndrome.
Fereshetian S, Upton J
Clin Plast Surg 1991 Apr;18(2):365-80. PMID: 2065494
Cleft hand.
Ogino T
Hand Clin 1990 Nov;6(4):661-71. PMID: 2176655

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...