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Abnormal intrahepatic bile duct morphology

MedGen UID:
869157
•Concept ID:
C4023577
•
Anatomical Abnormality
Synonym: Abnormality of the intrahepatic bile duct
 
HPO: HP:0011040

Definition

An abnormality of the intrahepatic bile duct. [from HPO]

Professional guidelines

PubMed

Associations between ultrasound screening findings and cholangiocarcinoma diagnosis in an at-risk population.
Thinkhamrop K, Khuntikeo N, Chamadol N, Suwannatrai AT, Phimha S, Kelly M
Sci Rep 2022 Aug 6;12(1):13513. doi: 10.1038/s41598-022-17794-9. PMID: 35933509Free PMC Article
Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma.
Aoki S, Inoue K, Klein S, Halvorsen S, Chen J, Matsui A, Nikmaneshi MR, Kitahara S, Hato T, Chen X, Kawakubo K, Nia HT, Chen I, Schanne DH, Mamessier E, Shigeta K, Kikuchi H, Ramjiawan RR, Schmidt TC, Iwasaki M, Yau T, Hong TS, Quaas A, Plum PS, Dima S, Popescu I, Bardeesy N, Munn LL, Borad MJ, Sassi S, Jain RK, Zhu AX, Duda DG
Gut 2022 Jan;71(1):185-193. Epub 2021 Jan 11 doi: 10.1136/gutjnl-2020-322493. PMID: 33431577Free PMC Article
Recent advances in the pathogenesis and management of biliary atresia.
Zagory JA, Nguyen MV, Wang KS
Curr Opin Pediatr 2015 Jun;27(3):389-94. doi: 10.1097/MOP.0000000000000214. PMID: 25944310Free PMC Article

Recent clinical studies

Etiology

Convergent MAPK pathway alterations mediate acquired resistance to FGFR inhibitors in FGFR2 fusion-positive cholangiocarcinoma.
DiPeri TP, Zhao M, Evans KW, Varadarajan K, Moss T, Scott S, Kahle MP, Byrnes CC, Chen H, Lee SS, Halim AB, Hirai H, Wacheck V, Kwong LN, Rodon J, Javle M, Meric-Bernstam F
J Hepatol 2024 Feb;80(2):322-334. Epub 2023 Nov 14 doi: 10.1016/j.jhep.2023.10.041. PMID: 37972659
Proteome Landscapes of Human Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.
Yi X, Zhu J, Liu W, Peng L, Lu C, Sun P, Huang L, Nie X, Huang S, Guo T, Zhu Y
Mol Cell Proteomics 2023 Aug;22(8):100604. Epub 2023 Jun 22 doi: 10.1016/j.mcpro.2023.100604. PMID: 37353004Free PMC Article
Imaging of choledochal cysts.
Lewis VA, Adam SZ, Nikolaidis P, Wood C, Wu JG, Yaghmai V, Miller FH
Abdom Imaging 2015 Aug;40(6):1567-80. doi: 10.1007/s00261-015-0381-4. PMID: 25682292
Congenital fibrocystic liver diseases.
Drenth JP, Chrispijn M, Bergmann C
Best Pract Res Clin Gastroenterol 2010 Oct;24(5):573-84. doi: 10.1016/j.bpg.2010.08.007. PMID: 20955960
Biliary atresia revisited.
Kahn E
Pediatr Dev Pathol 2004 Mar-Apr;7(2):109-24. Epub 2004 Mar 4 doi: 10.1007/s10024-003-0307-y. PMID: 14994122

Diagnosis

Circular RNAs in cholangiocarcinoma.
Liao W, Feng Q, Liu H, Du J, Chen X, Zeng Y
Cancer Lett 2023 Jan 28;553:215980. Epub 2022 Nov 4 doi: 10.1016/j.canlet.2022.215980. PMID: 36336149
Portal biliopathy.
Khuroo MS, Rather AA, Khuroo NS, Khuroo MS
World J Gastroenterol 2016 Sep 21;22(35):7973-82. doi: 10.3748/wjg.v22.i35.7973. PMID: 27672292Free PMC Article
Imaging of choledochal cysts.
Lewis VA, Adam SZ, Nikolaidis P, Wood C, Wu JG, Yaghmai V, Miller FH
Abdom Imaging 2015 Aug;40(6):1567-80. doi: 10.1007/s00261-015-0381-4. PMID: 25682292
Biliary atresia.
Mieli-Vergani G, Vergani D
Semin Immunopathol 2009 Sep;31(3):371-81. Epub 2009 Jun 17 doi: 10.1007/s00281-009-0171-6. PMID: 19533128
Alagille syndrome.
Krantz ID, Piccoli DA, Spinner NB
J Med Genet 1997 Feb;34(2):152-7. doi: 10.1136/jmg.34.2.152. PMID: 9039994Free PMC Article

Therapy

Pemigatinib: A Review in Advanced Cholangiocarcinoma.
Frampton JE
Target Oncol 2024 Jan;19(1):107-114. Epub 2024 Jan 11 doi: 10.1007/s11523-023-01024-x. PMID: 38206555
Convergent MAPK pathway alterations mediate acquired resistance to FGFR inhibitors in FGFR2 fusion-positive cholangiocarcinoma.
DiPeri TP, Zhao M, Evans KW, Varadarajan K, Moss T, Scott S, Kahle MP, Byrnes CC, Chen H, Lee SS, Halim AB, Hirai H, Wacheck V, Kwong LN, Rodon J, Javle M, Meric-Bernstam F
J Hepatol 2024 Feb;80(2):322-334. Epub 2023 Nov 14 doi: 10.1016/j.jhep.2023.10.041. PMID: 37972659
Laparoscopic cholecystectomy for left-sided gallbladder.
Jung YK, Choi D, Lee KG
Langenbecks Arch Surg 2022 Feb;407(1):207-212. Epub 2021 Jul 9 doi: 10.1007/s00423-021-02263-0. PMID: 34240246
Post-transplant cholangiopathy: Classification, pathogenesis, and preventive strategies.
de Vries Y, von Meijenfeldt FA, Porte RJ
Biochim Biophys Acta Mol Basis Dis 2018 Apr;1864(4 Pt B):1507-1515. Epub 2017 Jun 20 doi: 10.1016/j.bbadis.2017.06.013. PMID: 28645651
Portal biliopathy.
Khuroo MS, Rather AA, Khuroo NS, Khuroo MS
World J Gastroenterol 2016 Sep 21;22(35):7973-82. doi: 10.3748/wjg.v22.i35.7973. PMID: 27672292Free PMC Article

Prognosis

Circular RNAs in cholangiocarcinoma.
Liao W, Feng Q, Liu H, Du J, Chen X, Zeng Y
Cancer Lett 2023 Jan 28;553:215980. Epub 2022 Nov 4 doi: 10.1016/j.canlet.2022.215980. PMID: 36336149
Biliary atresia.
Mieli-Vergani G, Vergani D
Semin Immunopathol 2009 Sep;31(3):371-81. Epub 2009 Jun 17 doi: 10.1007/s00281-009-0171-6. PMID: 19533128
Primary biliary cirrhosis.
Moreno-Otero R, Lisker-Melman M, Jones EA
Med Clin North Am 1989 Jul;73(4):911-29. doi: 10.1016/s0025-7125(16)30645-9. PMID: 2657267
Neonatal cholestasis.
Balistreri WF
J Pediatr 1985 Feb;106(2):171-84. doi: 10.1016/s0022-3476(85)80282-1. PMID: 3881579
Caroli's disease.
Mercadier M, Chigot JP, Clot JP, Langlois P, Lansiaux P
World J Surg 1984 Feb;8(1):22-9. doi: 10.1007/BF01658359. PMID: 6367232

Clinical prediction guides

Pemigatinib: A Review in Advanced Cholangiocarcinoma.
Frampton JE
Target Oncol 2024 Jan;19(1):107-114. Epub 2024 Jan 11 doi: 10.1007/s11523-023-01024-x. PMID: 38206555
A preoperative scoring system to predict lymph node metastasis in intrahepatic cholangiocarcinoma.
Rhee H, Lim HJ, Han K, Yeom SK, Choi SH, Park JH, Cho ES, Park S, Lee MJ, Choi GH, Han DH, Lee SS, Park MS
Hepatol Int 2023 Aug;17(4):942-953. Epub 2023 Jan 23 doi: 10.1007/s12072-022-10477-7. PMID: 36689090
Circular RNAs in cholangiocarcinoma.
Liao W, Feng Q, Liu H, Du J, Chen X, Zeng Y
Cancer Lett 2023 Jan 28;553:215980. Epub 2022 Nov 4 doi: 10.1016/j.canlet.2022.215980. PMID: 36336149
Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling.
Zhao C, Matalonga J, Lancman JJ, Liu L, Xiao C, Kumar S, Gates KP, He J, Graves A, Huisken J, Azuma M, Lu Z, Chen C, Ding BS, Dong PDS
Proc Natl Acad Sci U S A 2022 Dec 13;119(50):e2201097119. Epub 2022 Dec 5 doi: 10.1073/pnas.2201097119. PMID: 36469766Free PMC Article
Diagnosis of IgG4-related sclerosing cholangitis.
Nakazawa T, Naitoh I, Hayashi K, Miyabe K, Simizu S, Joh T
World J Gastroenterol 2013 Nov 21;19(43):7661-70. doi: 10.3748/wjg.v19.i43.7661. PMID: 24282356Free PMC Article

Recent systematic reviews

Association of mucin family members with prognostic significance in pancreatic cancer patients: A meta-analysis.
Xu W, Zhang M, Liu L, Yin M, Xu C, Weng Z
PLoS One 2022;17(6):e0269612. Epub 2022 Jun 16 doi: 10.1371/journal.pone.0269612. PMID: 35709153Free PMC Article
Defining an optimal surveillance strategy for patients following choledochal cyst resection: results of a systematic review.
Koea J, O'Grady M, Agraval J, Srinivasa S
ANZ J Surg 2022 Jun;92(6):1356-1364. Epub 2022 May 17 doi: 10.1111/ans.17775. PMID: 35579057
Risk of malignancy in Caroli disease and syndrome: A systematic review.
Fahrner R, Dennler SG, Inderbitzin D
World J Gastroenterol 2020 Aug 21;26(31):4718-4728. doi: 10.3748/wjg.v26.i31.4718. PMID: 32884228Free PMC Article
Meta-analysis of risk of developing malignancy in congenital choledochal malformation.
Ten Hove A, de Meijer VE, Hulscher JBF, de Kleine RHJ
Br J Surg 2018 Apr;105(5):482-490. Epub 2018 Feb 26 doi: 10.1002/bjs.10798. PMID: 29480528Free PMC Article
Therapeutic approaches for portal biliopathy: A systematic review.
Franceschet I, Zanetto A, Ferrarese A, Burra P, Senzolo M
World J Gastroenterol 2016 Dec 7;22(45):9909-9920. doi: 10.3748/wjg.v22.i45.9909. PMID: 28018098Free PMC Article

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