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Abnormality of ocular abduction

MedGen UID:
868990
•Concept ID:
C4023405
•
Anatomical Abnormality
HPO: HP:0011347

Definition

An abnormality involving the movement of the eye outwards. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of ocular abduction

Professional guidelines

PubMed

Molecular genetic screening of MBS1 locus on chromosome 13 for microdeletions and exclusion of FGF9, GSH1 and CDX2 as causative genes in patients with Moebius syndrome.
Uzumcu A, Karaman B, Toksoy G, Uyguner ZO, Candan S, Eris H, Tatli B, Geckinli B, Yuksel A, Kayserili H, Basaran S
Eur J Med Genet 2009 Sep-Oct;52(5):315-20. Epub 2009 May 19 doi: 10.1016/j.ejmg.2009.05.003. PMID: 19460469

Recent clinical studies

Etiology

Surgical outcomes following strabismus surgery for abducens nerve palsy.
O'Brien JC, Melson AT, Bryant JC, Ding K, Farris BK, Siatkowski RM
J AAPOS 2023 Jun;27(3):142.e1-142.e6. Epub 2023 May 11 doi: 10.1016/j.jaapos.2023.04.003. PMID: 37179001
Medial rectus disinsertion for management of chronic complete sixth nerve palsy.
Bagheri A, Veisi A, Tavakoli M
Eur J Ophthalmol 2022 Sep;32(5):2622-2629. Epub 2021 Dec 22 doi: 10.1177/11206721211065214. PMID: 34935536
Variant types of Duane retraction syndrome: synergistic divergences and convergences.
Shen T, Kang Y, Deng D, Wang Z, Qiu X, Yan J
J AAPOS 2021 Feb;25(1):14.e1-14.e6. Epub 2021 Feb 17 doi: 10.1016/j.jaapos.2020.10.007. PMID: 33607271
Augmented superior rectus muscle transposition in management of defective ocular abduction.
Farid MF, Daifalla AEM, Awwad MA
BMC Ophthalmol 2021 Jan 20;21(1):50. doi: 10.1186/s12886-020-01779-1. PMID: 33472581Free PMC Article
Möbius and Möbius-like syndromes (TTV-OFM, OMLH).
Miller MT, Ray V, Owens P, Chen F
J Pediatr Ophthalmol Strabismus 1989 Jul-Aug;26(4):176-88. doi: 10.3928/0191-3913-19890701-07. PMID: 2668494

Diagnosis

Update on the medial longitudinal fasciculus syndrome.
Lee SH, Kim JM, Kim JS
Neurol Sci 2022 Jun;43(6):3533-3540. Epub 2022 Mar 8 doi: 10.1007/s10072-022-05967-3. PMID: 35258687
Retinal hemorrhage and bleeding disorders in children: A review.
Thau A, Saffren B, Zakrzewski H, Anderst JD, Carpenter SL, Levin A
Child Abuse Negl 2021 Feb;112:104901. Epub 2021 Jan 2 doi: 10.1016/j.chiabu.2020.104901. PMID: 33401159
The Eye Examination in the Evaluation of Child Abuse.
Christian CW, Levin AV; COUNCIL ON CHILD ABUSE AND NEGLECT; SECTION ON OPHTHALMOLOGY; AMERICAN ASSOCIATION OF CERTIFIED ORTHOPTISTS; AMERICAN ASSOCIATION FOR PEDIATRIC OPHTHALMOLOGY AND STRABISMUS; AMERICAN ACADEMY OF OPHTHALMOLOGY
Pediatrics 2018 Aug;142(2) doi: 10.1542/peds.2018-1411. PMID: 30037976
Duane retraction syndrome.
Alexandrakis G, Saunders RA
Ophthalmol Clin North Am 2001 Sep;14(3):407-17. doi: 10.1016/s0896-1549(05)70238-8. PMID: 11705140
Möbius and Möbius-like syndromes (TTV-OFM, OMLH).
Miller MT, Ray V, Owens P, Chen F
J Pediatr Ophthalmol Strabismus 1989 Jul-Aug;26(4):176-88. doi: 10.3928/0191-3913-19890701-07. PMID: 2668494

Therapy

Ocular motility changes after inferomedial wall and balanced medial plus lateral wall orbital decompression in Graves' orbitopathy: a randomized prospective comparative study.
Leite CA, Pereira TS, Chiang J, Moritz RB, Gonçalves ACP, Monteiro MLR
Clinics (Sao Paulo) 2021;76:e2592. Epub 2021 Apr 9 doi: 10.6061/clinics/2021/e2592. PMID: 33852655Free PMC Article
Clinical Course of Sarcoidosis in World Trade Center-Exposed Firefighters.
Hena KM, Yip J, Jaber N, Goldfarb D, Fullam K, Cleven K, Moir W, Zeig-Owens R, Webber MP, Spevack DM, Judson MA, Maier L, Krumerman A, Aizer A, Spivack SD, Berman J, Aldrich TK, Prezant DJ; FDNY Sarcoidosis Clinical Research Group*
Chest 2018 Jan;153(1):114-123. Epub 2017 Oct 21 doi: 10.1016/j.chest.2017.10.014. PMID: 29066387Free PMC Article
Prevalence of conjunctival shrinkage and its association with dry eye disease: results from a population-based study in Spain.
Viso E, Rodríguez-Ares MT, Bóveda FJ, Touriño R, Gude F
Cornea 2014 May;33(5):442-7. doi: 10.1097/ICO.0000000000000091. PMID: 24622297
The puzzle of autism: an ophthalmologic contribution.
Miller MT, Strömland K, Gillberg C, Johansson M, Nilsson EW
Trans Am Ophthalmol Soc 1998;96:369-85; discussion 385-7. PMID: 10360298Free PMC Article
Sarin poisoning on Tokyo subway.
Ohbu S, Yamashina A, Takasu N, Yamaguchi T, Murai T, Nakano K, Matsui Y, Mikami R, Sakurai K, Hinohara S
South Med J 1997 Jun;90(6):587-93. doi: 10.1097/00007611-199706000-00002. PMID: 9191733

Prognosis

Surgical outcomes following strabismus surgery for abducens nerve palsy.
O'Brien JC, Melson AT, Bryant JC, Ding K, Farris BK, Siatkowski RM
J AAPOS 2023 Jun;27(3):142.e1-142.e6. Epub 2023 May 11 doi: 10.1016/j.jaapos.2023.04.003. PMID: 37179001
Motility of the Ocular Prosthesis in Anophthalmic Patients: Objective and Patient-perceived Findings.
van Renterghem V, Ruiters S, Mombaerts I
Orbit 2023 Aug;42(4):383-388. Epub 2022 Aug 4 doi: 10.1080/01676830.2022.2107687. PMID: 35924421
Augmented lateral rectus muscle recession for treatment of infantile exotropia.
Huang L, Li N
Int Ophthalmol 2022 May;42(5):1589-1594. Epub 2022 Jan 29 doi: 10.1007/s10792-021-02152-x. PMID: 35091974
Long-term outcomes of strabismus surgery in Mobius sequence.
Lueder GT, Galli M
Strabismus 2019 Jun;27(2):43-46. Epub 2019 Apr 8 doi: 10.1080/09273972.2019.1599402. PMID: 30958093
Clinical Course of Sarcoidosis in World Trade Center-Exposed Firefighters.
Hena KM, Yip J, Jaber N, Goldfarb D, Fullam K, Cleven K, Moir W, Zeig-Owens R, Webber MP, Spevack DM, Judson MA, Maier L, Krumerman A, Aizer A, Spivack SD, Berman J, Aldrich TK, Prezant DJ; FDNY Sarcoidosis Clinical Research Group*
Chest 2018 Jan;153(1):114-123. Epub 2017 Oct 21 doi: 10.1016/j.chest.2017.10.014. PMID: 29066387Free PMC Article

Clinical prediction guides

Surgical outcomes following strabismus surgery for abducens nerve palsy.
O'Brien JC, Melson AT, Bryant JC, Ding K, Farris BK, Siatkowski RM
J AAPOS 2023 Jun;27(3):142.e1-142.e6. Epub 2023 May 11 doi: 10.1016/j.jaapos.2023.04.003. PMID: 37179001
Motility of the Ocular Prosthesis in Anophthalmic Patients: Objective and Patient-perceived Findings.
van Renterghem V, Ruiters S, Mombaerts I
Orbit 2023 Aug;42(4):383-388. Epub 2022 Aug 4 doi: 10.1080/01676830.2022.2107687. PMID: 35924421
Update on the medial longitudinal fasciculus syndrome.
Lee SH, Kim JM, Kim JS
Neurol Sci 2022 Jun;43(6):3533-3540. Epub 2022 Mar 8 doi: 10.1007/s10072-022-05967-3. PMID: 35258687
Neuro-ophthalmic manifestations of the syndrome of ophthalmoplegia, ataxia and areflexia: a review.
al-Din SN, Anderson M, Eeg-Olofsson O, Trontelj JV
Acta Neurol Scand 1994 Mar;89(3):157-63. doi: 10.1111/j.1600-0404.1994.tb01654.x. PMID: 8030396
Möbius and Möbius-like syndromes (TTV-OFM, OMLH).
Miller MT, Ray V, Owens P, Chen F
J Pediatr Ophthalmol Strabismus 1989 Jul-Aug;26(4):176-88. doi: 10.3928/0191-3913-19890701-07. PMID: 2668494

Recent systematic reviews

Retinal hemorrhage and bleeding disorders in children: A review.
Thau A, Saffren B, Zakrzewski H, Anderst JD, Carpenter SL, Levin A
Child Abuse Negl 2021 Feb;112:104901. Epub 2021 Jan 2 doi: 10.1016/j.chiabu.2020.104901. PMID: 33401159

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