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Abnormal direction of ventricular apex

MedGen UID:
868864
•Concept ID:
C4023275
•
Anatomical Abnormality
HPO: HP:0011600

Definition

Abnormal plane of direction of the heart from the base to the apex. Left sided is normal. [from HPO]

Recent clinical studies

Etiology

Percutaneous Transapical Left Ventricular Access to Treat Paravalvular Leak and Ventricular Septal Defect.
Venturini JM, McClelland I, Blair JEA, Narang A, Kalathiya R, Lang RM, Addetia K, Paul J, Nathan S, Shah AP
J Invasive Cardiol 2019 Sep;31(9):247-252. Epub 2019 Jun 15 PMID: 31199350Free PMC Article
Evaluation of Acquired Valvular Heart Disease by the Pediatrician: When to Follow, When to Refer for Intervention? Part I.
Saxena A
Indian J Pediatr 2015 Nov;82(11):1033-41. Epub 2015 Jul 5 doi: 10.1007/s12098-015-1796-1. PMID: 26141545
Perioperative assessment of myocardial deformation.
Duncan AE, Alfirevic A, Sessler DI, Popovic ZB, Thomas JD
Anesth Analg 2014 Mar;118(3):525-44. doi: 10.1213/ANE.0000000000000088. PMID: 24557101Free PMC Article
Left ventricular twist in left ventricular noncompaction.
Peters F, Khandheria BK, Libhaber E, Maharaj N, Dos Santos C, Matioda H, Essop MR
Eur Heart J Cardiovasc Imaging 2014 Jan;15(1):48-55. Epub 2013 Jun 21 doi: 10.1093/ehjci/jet076. PMID: 23793875
Borderline left ventricle.
Corno AF
Eur J Cardiothorac Surg 2005 Jan;27(1):67-73. doi: 10.1016/j.ejcts.2004.10.034. PMID: 15621473

Diagnosis

Percutaneous Transapical Left Ventricular Access to Treat Paravalvular Leak and Ventricular Septal Defect.
Venturini JM, McClelland I, Blair JEA, Narang A, Kalathiya R, Lang RM, Addetia K, Paul J, Nathan S, Shah AP
J Invasive Cardiol 2019 Sep;31(9):247-252. Epub 2019 Jun 15 PMID: 31199350Free PMC Article
Biventricular fibroma resection in an adult.
Ascaso M, Astrosa E, Moscoso B, Fernandez A, Barriuso C, Castella M
Multimed Man Cardiothorac Surg 2019 Mar 12;2019 doi: 10.1510/mmcts.2019.010. PMID: 30990581
Evaluation of Acquired Valvular Heart Disease by the Pediatrician: When to Follow, When to Refer for Intervention? Part I.
Saxena A
Indian J Pediatr 2015 Nov;82(11):1033-41. Epub 2015 Jul 5 doi: 10.1007/s12098-015-1796-1. PMID: 26141545
Left ventricular twist in left ventricular noncompaction.
Peters F, Khandheria BK, Libhaber E, Maharaj N, Dos Santos C, Matioda H, Essop MR
Eur Heart J Cardiovasc Imaging 2014 Jan;15(1):48-55. Epub 2013 Jun 21 doi: 10.1093/ehjci/jet076. PMID: 23793875
Usefulness of the 12-lead electrocardiogram in the follow-up of patients with cardiac resynchronization devices. Part I.
Barold SS, Herweg B
Cardiol J 2011;18(5):476-86. doi: 10.5603/cj.2011.0002. PMID: 21947982

Therapy

Right ventricular mechanical pattern in health and disease: beyond longitudinal shortening.
Kovács A, Lakatos B, Tokodi M, Merkely B
Heart Fail Rev 2019 Jul;24(4):511-520. doi: 10.1007/s10741-019-09778-1. PMID: 30852772Free PMC Article
Selective pacing sites.
Coppola G, La Greca C, Corrado E, Ajello L, Nogara A, Ciaramitaro G, Augugliaro S, Novo G, Novo S, Assennato P
Minerva Cardioangiol 2015 Apr;63(2):151-60. PMID: 25711837
Usefulness of the 12-lead electrocardiogram in the follow-up of patients with cardiac resynchronization devices. Part I.
Barold SS, Herweg B
Cardiol J 2011;18(5):476-86. doi: 10.5603/cj.2011.0002. PMID: 21947982
Pediatric cardiac resynchronization pacing therapy.
Karpawich PP
Curr Opin Cardiol 2007 Mar;22(2):72-6. doi: 10.1097/HCO.0b013e328014a849. PMID: 17284983
The deleterious consequences of right ventricular apical pacing: time to seek alternate site pacing.
Manolis AS
Pacing Clin Electrophysiol 2006 Mar;29(3):298-315. doi: 10.1111/j.1540-8159.2006.00338.x. PMID: 16606399

Prognosis

Increased biventricular hemodynamic forces in precapillary pulmonary hypertension.
Pola K, Bergström E, Töger J, Rådegran G, Arvidsson PM, Carlsson M, Arheden H, Ostenfeld E
Sci Rep 2022 Nov 19;12(1):19933. doi: 10.1038/s41598-022-24267-6. PMID: 36402861Free PMC Article
Aorto-Right Ventricular Tunnel: A Case Series and Literature Review.
Miette A, Nuri HA, Pomé G, Santini F
Semin Thorac Cardiovasc Surg 2020 Winter;32(4):876-880. Epub 2020 May 17 doi: 10.1053/j.semtcvs.2020.05.004. PMID: 32428576
Percutaneous Transapical Left Ventricular Access to Treat Paravalvular Leak and Ventricular Septal Defect.
Venturini JM, McClelland I, Blair JEA, Narang A, Kalathiya R, Lang RM, Addetia K, Paul J, Nathan S, Shah AP
J Invasive Cardiol 2019 Sep;31(9):247-252. Epub 2019 Jun 15 PMID: 31199350Free PMC Article
Right ventricular mechanical pattern in health and disease: beyond longitudinal shortening.
Kovács A, Lakatos B, Tokodi M, Merkely B
Heart Fail Rev 2019 Jul;24(4):511-520. doi: 10.1007/s10741-019-09778-1. PMID: 30852772Free PMC Article
Perioperative assessment of myocardial deformation.
Duncan AE, Alfirevic A, Sessler DI, Popovic ZB, Thomas JD
Anesth Analg 2014 Mar;118(3):525-44. doi: 10.1213/ANE.0000000000000088. PMID: 24557101Free PMC Article

Clinical prediction guides

Selective pacing sites.
Coppola G, La Greca C, Corrado E, Ajello L, Nogara A, Ciaramitaro G, Augugliaro S, Novo G, Novo S, Assennato P
Minerva Cardioangiol 2015 Apr;63(2):151-60. PMID: 25711837
Perioperative assessment of myocardial deformation.
Duncan AE, Alfirevic A, Sessler DI, Popovic ZB, Thomas JD
Anesth Analg 2014 Mar;118(3):525-44. doi: 10.1213/ANE.0000000000000088. PMID: 24557101Free PMC Article
Usefulness of the 12-lead electrocardiogram in the follow-up of patients with cardiac resynchronization devices. Part I.
Barold SS, Herweg B
Cardiol J 2011;18(5):476-86. doi: 10.5603/cj.2011.0002. PMID: 21947982
Determinants of left ventricular shear strain.
Bovendeerd PH, Kroon W, Delhaas T
Am J Physiol Heart Circ Physiol 2009 Sep;297(3):H1058-68. Epub 2009 Jul 10 doi: 10.1152/ajpheart.01334.2008. PMID: 19592607
The mechanism of emergence and clinical significance of apically directed intraventricular flow during isovolumic relaxation.
Ohte N, Narita H, Akita S, Kurokawa K, Hayano J, Sugawara M, Kimura G
J Am Soc Echocardiogr 2002 Jul;15(7):715-22. doi: 10.1067/mje.2002.119113. PMID: 12094170

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