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Intracranial dermoid cyst

MedGen UID:
868643
•Concept ID:
C4023044
•
Congenital Abnormality
HPO: HP:0012097

Definition

A congenital inclusion cysts that arises from the inclusion of ectodermally committed cells at the time of neural tube closure (3rd-5th week of embryogenesis). The capsule of dermoid cysts consists of simple epithelium supported by collagen. In thicker parts, the lining is supplemented with dermis containing hair follicles, sebaceous glands, and apocrine glands. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntracranial dermoid cyst

Professional guidelines

PubMed

Diagnosis and treatment of congenital nasal dermoid and sinus cysts in 11 infants: A consort compliant study.
Ni K, Li X, Zhao L, Wu J, Liu X, Shi H
Medicine (Baltimore) 2020 May 22;99(21):e19435. doi: 10.1097/MD.0000000000019435. PMID: 32481248Free PMC Article
Scalp dermoids: a review of their anatomy, diagnosis, and treatment.
Sorenson EP, Powel JE, Rozzelle CJ, Tubbs RS, Loukas M
Childs Nerv Syst 2013 Mar;29(3):375-80. Epub 2012 Nov 21 doi: 10.1007/s00381-012-1946-y. PMID: 23180312
Orbital dermoid cyst of childhood: clinical pathologic findings, classification and management.
Cavazza S, Laffi GL, Lodi L, Gasparrini E, Tassinari G
Int Ophthalmol 2011 Apr;31(2):93-7. Epub 2011 Jan 26 doi: 10.1007/s10792-011-9419-y. PMID: 21267629

Recent clinical studies

Etiology

Intracranial dermoid cyst rupture-related brain ischemia: Case report and hemodynamic study.
Jin H, Guo ZN, Luo Y, Zhao R, Sun MS, Yang Y
Medicine (Baltimore) 2017 Jan;96(4):e5631. doi: 10.1097/MD.0000000000005631. PMID: 28121918Free PMC Article
Progressive visual loss following rupture of an intracranial dermoid cyst.
Skovrlj B, Mascitelli JR, Steinberger JM, Weiss N
J Clin Neurosci 2014 Jan;21(1):159-61. Epub 2013 Jul 27 doi: 10.1016/j.jocn.2013.02.005. PMID: 23896550
Delayed ischemic deficit after resection of a large intracranial dermoid: case report and review of the literature.
Ecker RD, Atkinson JL, Nichols DA
Neurosurgery 2003 Mar;52(3):706-10; discussion 709-10. doi: 10.1227/01.neu.0000048482.27700.3b. PMID: 12590698
Shadow cells in an intracranial dermoid cyst.
Hitchcock MG, Ellington KS, Friedman AH, Provenzaie JM, McLendon RE
Arch Pathol Lab Med 1995 Apr;119(4):371-3. PMID: 7726731
Diagnosis of ruptured intracranial dermoid cyst: value MR over CT.
Smith AS, Benson JE, Blaser SI, Mizushima A, Tarr RW, Bellon EM
AJNR Am J Neuroradiol 1991 Jan-Feb;12(1):175-80. PMID: 1903577Free PMC Article

Diagnosis

Intracranial Dermoid Cyst.
Lakhani DA, Morris MO, Deng F
Radiology 2024 Apr;311(1):e232952. doi: 10.1148/radiol.232952. PMID: 38687215
Sebaceous adenoma occurring within an intracranial dermoid cyst.
Minamisaka T, Imura J, Shiraishi K, Takagi K, Tomia T, Tanaka S, Noguchi A, Akai T, Noguchi K, Kuroda S
Neuropathology 2022 Aug;42(4):289-294. Epub 2022 May 25 doi: 10.1111/neup.12806. PMID: 35614379
Intracranial dermoid cyst rupture-related brain ischemia: Case report and hemodynamic study.
Jin H, Guo ZN, Luo Y, Zhao R, Sun MS, Yang Y
Medicine (Baltimore) 2017 Jan;96(4):e5631. doi: 10.1097/MD.0000000000005631. PMID: 28121918Free PMC Article
Ruptured intracranial dermoid cyst.
Nittala PP, Thomas VV
Ann Saudi Med 2012 Jul-Aug;32(4):438-9. doi: 10.5144/0256-4947.2012.438. PMID: 22705621Free PMC Article
Diagnosis of ruptured intracranial dermoid cyst: value MR over CT.
Smith AS, Benson JE, Blaser SI, Mizushima A, Tarr RW, Bellon EM
AJNR Am J Neuroradiol 1991 Jan-Feb;12(1):175-80. PMID: 1903577Free PMC Article

Therapy

Heightened seizure susceptibility associated with brain dermoid cyst and the administration of human chorionic gonadotropin (hCG).
Milani P, Rocchi R, Cerase A, Rossi A, Mazzocchio R
J Neurol Sci 2007 Jul 15;258(1-2):144-7. Epub 2007 Mar 29 doi: 10.1016/j.jns.2007.02.030. PMID: 17395206

Prognosis

Intracranial dermoid cyst rupture-related brain ischemia: Case report and hemodynamic study.
Jin H, Guo ZN, Luo Y, Zhao R, Sun MS, Yang Y
Medicine (Baltimore) 2017 Jan;96(4):e5631. doi: 10.1097/MD.0000000000005631. PMID: 28121918Free PMC Article
Multiple low (fat) attenuating lesions associated with an intracranial dermoid cyst: multiple dermoids or cyst rupture? A case report.
Hekster RE, Lambooy N
Diagn Imaging 1981;50(4):229-31. PMID: 7297389

Recent systematic reviews

Intrasellar Dermoid Cyst: Case Report of a Rare Lesion and Systematic Literature Review Comparing Intrasellar, Suprasellar, and Parasellar Locations.
Donofrio CA, Bertazzoni G, Riccio L, Pinacoli A, Pianta L, Generali D, Ungari M, Servadei F, Roncaroli F, Fioravanti A
World Neurosurg 2024 Feb;182:83-90. Epub 2023 Nov 22 doi: 10.1016/j.wneu.2023.11.057. PMID: 37995988
Headache in Ruptured Intracranial Dermoid Cysts.
Tolebeyan AS, Kuruvilla DE
Curr Pain Headache Rep 2020 May 29;24(7):31. doi: 10.1007/s11916-020-00863-x. PMID: 32472229

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