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Abnormal alpha granule distribution

MedGen UID:
868471
Concept ID:
C4022865
Anatomical Abnormality
HPO: HP:0012525

Definition

An anomalous location and arrangement of platelet alpha granules. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal alpha granule distribution

Recent clinical studies

Etiology

Reus-Chavarría E, Martínez-Vieyra I, Salinas-Nolasco C, Chávez-Piña AE, Méndez-Méndez JV, López-Villegas EO, Sosa-Peinado A, Cerecedo D
Biochim Biophys Acta Biomembr 2019 Feb 1;1861(2):387-402. Epub 2018 Nov 10 doi: 10.1016/j.bbamem.2018.11.003. PMID: 30423324
White JG
Platelets 2007 Nov;18(7):522-7. doi: 10.1080/09537100701280670. PMID: 17957568
Liu D, Shen D, Zou P, Wei W, Wang A, Yang R
J Tongji Med Univ 1997;17(1):21-4. doi: 10.1007/BF02887996. PMID: 9639779
Eguchi M, Ozawa T, Sakakibara H, Sugita K, Iwama Y, Furukawa T
Cancer 1992 Jul 15;70(2):451-8. doi: 10.1002/1097-0142(19920715)70:2<451::aid-cncr2820700213>3.0.co;2-v. PMID: 1319816
Boneu B, Sié P, Eche N, Caranobe C, Hugo B, Nouvel C
Br J Haematol 1983 Nov;55(3):523-32. doi: 10.1111/j.1365-2141.1983.tb02167.x. PMID: 6227333

Diagnosis

Jayakody H, Zarei S, Nguyen H, Dalton J, Chen K, Hudgins L, Day J, Withrow K, Pandya A, Teasley J, Dobyns WB, Mathews KD, Moore SA
J Neuropathol Exp Neurol 2020 Sep 1;79(9):998-1010. doi: 10.1093/jnen/nlaa062. PMID: 32827036Free PMC Article
Yao M, Yao DF, Bian YZ, Wu W, Yan XD, Yu DD, Qiu LW, Yang JL, Zhang HJ, Sai WL, Chen J
Hepatobiliary Pancreat Dis Int 2013 Apr;12(2):171-9. doi: 10.1016/s1499-3872(13)60028-4. PMID: 23558072
White JG
Platelets 2007 Nov;18(7):522-7. doi: 10.1080/09537100701280670. PMID: 17957568
Ishiwata I, Yasuda M, Hirano T, Ishikawa H
Hum Cell 2007 Nov;20(4):119-30. doi: 10.1111/j.1749-0774.2007.00039.x. PMID: 17949352
Uchino J, Hata Y, Sasaki F, Une Y, Itoh T, Kasai Y
Jpn J Surg 1981;11(6):449-53. doi: 10.1007/BF02469029. PMID: 6173507

Therapy

Reus-Chavarría E, Martínez-Vieyra I, Salinas-Nolasco C, Chávez-Piña AE, Méndez-Méndez JV, López-Villegas EO, Sosa-Peinado A, Cerecedo D
Biochim Biophys Acta Biomembr 2019 Feb 1;1861(2):387-402. Epub 2018 Nov 10 doi: 10.1016/j.bbamem.2018.11.003. PMID: 30423324

Prognosis

Yao M, Yao DF, Bian YZ, Wu W, Yan XD, Yu DD, Qiu LW, Yang JL, Zhang HJ, Sai WL, Chen J
Hepatobiliary Pancreat Dis Int 2013 Apr;12(2):171-9. doi: 10.1016/s1499-3872(13)60028-4. PMID: 23558072

Clinical prediction guides

Jayakody H, Zarei S, Nguyen H, Dalton J, Chen K, Hudgins L, Day J, Withrow K, Pandya A, Teasley J, Dobyns WB, Mathews KD, Moore SA
J Neuropathol Exp Neurol 2020 Sep 1;79(9):998-1010. doi: 10.1093/jnen/nlaa062. PMID: 32827036Free PMC Article
Nury T, Sghaier R, Zarrouk A, Ménétrier F, Uzun T, Leoni V, Caccia C, Meddeb W, Namsi A, Sassi K, Mihoubi W, Riedinger JM, Cherkaoui-Malki M, Moreau T, Vejux A, Lizard G
Biochimie 2018 Oct;153:181-202. Epub 2018 Jul 19 doi: 10.1016/j.biochi.2018.07.009. PMID: 30031877
Liu D, Wang X, Qin W, Chen J, Wang Y, Zhuang M, Sun B
Sci Rep 2016 Mar 29;6:23653. doi: 10.1038/srep23653. PMID: 27020460Free PMC Article
Yao M, Yao DF, Bian YZ, Wu W, Yan XD, Yu DD, Qiu LW, Yang JL, Zhang HJ, Sai WL, Chen J
Hepatobiliary Pancreat Dis Int 2013 Apr;12(2):171-9. doi: 10.1016/s1499-3872(13)60028-4. PMID: 23558072
Berger G, Caen JP, Berndt MC, Cramer EM
Blood 1993 Nov 15;82(10):3034-44. PMID: 7693034

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