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Abnormal urine magnesium concentration

MedGen UID:
868429
•Concept ID:
C4022823
•
Finding
HPO: HP:0012607

Definition

An abnormal concentration of magnesium the urine. [from HPO]

Professional guidelines

PubMed

Urinary citrate and renal stone disease: the preventive role of alkali citrate treatment.
Caudarella R, Vescini F
Arch Ital Urol Androl 2009 Sep;81(3):182-7. PMID: 19911682
Phosphate replacement during treatment of diabetic ketosis. Effects on calcium and phosphorus homeostasis.
Becker DJ, Brown DR, Steranka BH, Drash AL
Am J Dis Child 1983 Mar;137(3):241-6. doi: 10.1001/archpedi.1983.02140290033009. PMID: 6401918

Recent clinical studies

Etiology

Cardiorenal syndrome in thalassemia patients.
Makmettakul S, Tantiworawit A, Phrommintikul A, Piriyakhuntorn P, Rattanathammethee T, Hantrakool S, Chai-Adisaksopha C, Rattarittamrong E, Norasetthada L, Fanhchaksai K, Charoenkwan P, Lekawanvijit S
BMC Nephrol 2020 Aug 3;21(1):325. doi: 10.1186/s12882-020-01990-8. PMID: 32746879Free PMC Article
Bacteria, Bones, and Stones: Managing Complications of Short Bowel Syndrome.
Johnson E, Vu L, Matarese LE
Nutr Clin Pract 2018 Aug;33(4):454-466. Epub 2018 Jun 21 doi: 10.1002/ncp.10113. PMID: 29926935
Magnesium hydrogen carbonate natural mineral water enriched with K(+)-citrate and vitamin B6 improves urinary abnormalities in patients with calcium oxalate nephrolithiasis.
Bren A, Kmetec A, Kveder R, Kaplan-Pavlovcic S
Urol Int 1998;60(2):105-7. doi: 10.1159/000030221. PMID: 9563149
Phosphate replacement during treatment of diabetic ketosis. Effects on calcium and phosphorus homeostasis.
Becker DJ, Brown DR, Steranka BH, Drash AL
Am J Dis Child 1983 Mar;137(3):241-6. doi: 10.1001/archpedi.1983.02140290033009. PMID: 6401918
Excretion of inhibitors of calcification in urine. Part I. Findings in control subjects and patients with renal stones.
Oreopoulos DG, Walker D, Akriotis DJ, Roncari DA, Husdan H, Symvoulidis A, Deveber GA, Rapoport A, Reid DB
Can Med Assoc J 1975 Apr 5;112(7):827-31. PMID: 1122457Free PMC Article

Diagnosis

Cardiorenal syndrome in thalassemia patients.
Makmettakul S, Tantiworawit A, Phrommintikul A, Piriyakhuntorn P, Rattanathammethee T, Hantrakool S, Chai-Adisaksopha C, Rattarittamrong E, Norasetthada L, Fanhchaksai K, Charoenkwan P, Lekawanvijit S
BMC Nephrol 2020 Aug 3;21(1):325. doi: 10.1186/s12882-020-01990-8. PMID: 32746879Free PMC Article
Urinary metabolic abnormalities in children with idiopathic hematuria.
Valavi E, Nickavar A, Aeene A
J Pediatr Urol 2019 Apr;15(2):165.e1-165.e4. Epub 2018 Nov 10 doi: 10.1016/j.jpurol.2018.11.003. PMID: 30528095
Abnormal renal magnesium handling.
Sutton RA, Domrongkitchaiporn S
Miner Electrolyte Metab 1993;19(4-5):232-40. PMID: 8264509
A neonate with idiopathic hyperaldosteronism.
Veenhoven RH, Vande Walle JG, Donckerwolcke RA, Wit JM, Griffiven AW, Derkx FH, Schalekamp MA
Pediatr Nephrol 1991 Nov;5(6):680-4. doi: 10.1007/BF00857870. PMID: 1768577
Renal tubular involvement mimicking Bartter syndrome in a patient with Kearns-Sayre syndrome.
Goto Y, Itami N, Kajii N, Tochimaru H, Endo M, Horai S
J Pediatr 1990 Jun;116(6):904-10. doi: 10.1016/s0022-3476(05)80648-1. PMID: 2161456

Therapy

Effects of water balance, diet and antidiuretic-hormone administration on the renal excretion of water.
de Rouffignac C
Scand J Urol Nephrol Suppl 1999;202:31-5. doi: 10.1080/003655999750169411. PMID: 10573789
Magnesium hydrogen carbonate natural mineral water enriched with K(+)-citrate and vitamin B6 improves urinary abnormalities in patients with calcium oxalate nephrolithiasis.
Bren A, Kmetec A, Kveder R, Kaplan-Pavlovcic S
Urol Int 1998;60(2):105-7. doi: 10.1159/000030221. PMID: 9563149
A neonate with idiopathic hyperaldosteronism.
Veenhoven RH, Vande Walle JG, Donckerwolcke RA, Wit JM, Griffiven AW, Derkx FH, Schalekamp MA
Pediatr Nephrol 1991 Nov;5(6):680-4. doi: 10.1007/BF00857870. PMID: 1768577
TmMg and renal Mg threshold in normal man and in certain pathophysiologic conditions.
Rude RK, Ryzen E
Magnesium 1986;5(5-6):273-81. PMID: 3807421
Metabolic alkalosis and acid urine following open-heart surgery with cardiopulmonary bypass.
Grigor KC
Br J Anaesth 1968 Dec;40(12):943-60. doi: 10.1093/bja/40.12.943. PMID: 4974837

Prognosis

Urinary minerals excretion among primary schoolchildren in Dubai-United Arab Emirates.
Al Ghali R, El-Mallah C, Obeid O, El-Saleh O, Smail L, Haroun D
PLoS One 2021;16(8):e0255195. Epub 2021 Aug 5 doi: 10.1371/journal.pone.0255195. PMID: 34351961Free PMC Article
Development and validation of Prediction models for Risks of complications in Early-onset Pre-eclampsia (PREP): a prospective cohort study.
Thangaratinam S, Allotey J, Marlin N, Mol BW, Von Dadelszen P, Ganzevoort W, Akkermans J, Ahmed A, Daniels J, Deeks J, Ismail K, Barnard AM, Dodds J, Kerry S, Moons C, Riley RD, Khan KS
Health Technol Assess 2017 Apr;21(18):1-100. doi: 10.3310/hta21180. PMID: 28412995Free PMC Article
Urinary citrate and renal stone disease: the preventive role of alkali citrate treatment.
Caudarella R, Vescini F
Arch Ital Urol Androl 2009 Sep;81(3):182-7. PMID: 19911682
The importance of magnesium status in the pathophysiology of mitral valve prolapse.
Bobkowski W, Nowak A, Durlach J
Magnes Res 2005 Mar;18(1):35-52. PMID: 15945614
Magnesium hydrogen carbonate natural mineral water enriched with K(+)-citrate and vitamin B6 improves urinary abnormalities in patients with calcium oxalate nephrolithiasis.
Bren A, Kmetec A, Kveder R, Kaplan-Pavlovcic S
Urol Int 1998;60(2):105-7. doi: 10.1159/000030221. PMID: 9563149

Clinical prediction guides

Prevalence of metabolic abnormalities in patients with urolithiasis in Kinshasa, Democratic Republic of Congo.
Diangienda PKD, Moningo DM, Sumaili EK, Mayindu AN, Punga-Maole AML, Haymann JP, Daudon M
Pan Afr Med J 2021;40:75. Epub 2021 Oct 5 doi: 10.11604/pamj.2021.40.75.28349. PMID: 34804342Free PMC Article
Urinary minerals excretion among primary schoolchildren in Dubai-United Arab Emirates.
Al Ghali R, El-Mallah C, Obeid O, El-Saleh O, Smail L, Haroun D
PLoS One 2021;16(8):e0255195. Epub 2021 Aug 5 doi: 10.1371/journal.pone.0255195. PMID: 34351961Free PMC Article
Urinary citrate and renal stone disease: the preventive role of alkali citrate treatment.
Caudarella R, Vescini F
Arch Ital Urol Androl 2009 Sep;81(3):182-7. PMID: 19911682
Omega-3 fatty acid status in attention-deficit/hyperactivity disorder.
Antalis CJ, Stevens LJ, Campbell M, Pazdro R, Ericson K, Burgess JR
Prostaglandins Leukot Essent Fatty Acids 2006 Oct-Nov;75(4-5):299-308. Epub 2006 Sep 8 doi: 10.1016/j.plefa.2006.07.004. PMID: 16962757
Renal tubular involvement mimicking Bartter syndrome in a patient with Kearns-Sayre syndrome.
Goto Y, Itami N, Kajii N, Tochimaru H, Endo M, Horai S
J Pediatr 1990 Jun;116(6):904-10. doi: 10.1016/s0022-3476(05)80648-1. PMID: 2161456

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