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Facial muscle hypertrophy

MedGen UID:
868297
•Concept ID:
C4022691
•
Finding
Synonyms: Hyperplasia of facial muscles; Increased size of facial muscles; Large facial muscles
 
HPO: HP:0012892

Definition

Hypertrophy of one or more muscles innervated by the facial nerve (the seventh cranial nerve). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFacial muscle hypertrophy

Professional guidelines

PubMed

International Consensus Recommendations on the Aesthetic Usage of Ready-to-Use AbobotulinumtoxinA (Alluzience).
Ascher B, Rzany BJ, Kestemont P, Redaelli A, Hendrickx B, Iozzo I, Martschin C, Milotich A, Molina B, Cartier H, Picaut P, Prygova I
Aesthet Surg J 2024 Jan 16;44(2):192-202. doi: 10.1093/asj/sjad222. PMID: 37490767Free PMC Article
Phenotype Genotype Characterization of FKRP-related Muscular Dystrophy among Indian Patients.
Unnikrishnan G, Polavarapu K, Bardhan M, Nashi S, Vengalil S, Preethish-Kumar V, Valasani RK, Huddar A, Nishadham V, Nandeesh BN, Nalini A
J Neuromuscul Dis 2023;10(4):615-626. doi: 10.3233/JND-221618. PMID: 37154180Free PMC Article
Prevention and treatment of nonfacial scars.
Keaney TC
Semin Cutan Med Surg 2015 Sep;34(3):153-7. doi: 10.12788/j.sder.2015.0167. PMID: 26566572

Recent clinical studies

Etiology

Exploring botulinum toxin's impact on masseter hypertrophy: a randomized, triple-blinded clinical trial.
de Souza Nobre BB, Rezende L, Barbosa Câmara-Souza M, Sanchez-Ayala A, Blass R, Carbone AC, Manso AC, Ernberg M, Christidis N, De la Torre Canales G
Sci Rep 2024 Jun 24;14(1):14522. doi: 10.1038/s41598-024-65395-5. PMID: 38914688Free PMC Article
Alternative Clinical Indications of Botulinum Toxin.
Alster TS, Harrison IS
Am J Clin Dermatol 2020 Dec;21(6):855-880. doi: 10.1007/s40257-020-00532-0. PMID: 32651806
The Masseter Muscle and Its Role in Facial Contouring, Aging, and Quality of Life: A Literature Review.
Almukhtar RM, Fabi SG
Plast Reconstr Surg 2019 Jan;143(1):39e-48e. doi: 10.1097/PRS.0000000000005083. PMID: 30303926
Association between signs and symptoms of bruxism and presence of tori: a systematic review.
Bertazzo-Silveira E, Stuginski-Barbosa J, Porporatti AL, Dick B, Flores-Mir C, Manfredini D, De Luca Canto G
Clin Oral Investig 2017 Dec;21(9):2789-2799. Epub 2017 Feb 17 doi: 10.1007/s00784-017-2081-7. PMID: 28213765
Botulinum toxin for masseter hypertrophy.
Fedorowicz Z, van Zuuren EJ, Schoones J
Cochrane Database Syst Rev 2013 Sep 9;2013(9):CD007510. doi: 10.1002/14651858.CD007510.pub3. PMID: 24018587Free PMC Article

Diagnosis

Concurrent fabry disease and immunoglobulin a nephropathy: a case report.
Zhou LN, Dong SS, Zhang SZ, Huang LW, Huang W
BMC Nephrol 2023 Nov 1;24(1):324. doi: 10.1186/s12882-023-03282-3. PMID: 37914990Free PMC Article
Deep Neck Lift: Defining Anatomical Problems and Choosing Appropriate Treatment Strategies.
Marten T, Elyassnia D
Facial Plast Surg 2022 Dec;38(6):630-649. Epub 2022 Dec 23 doi: 10.1055/s-0042-1757729. PMID: 36563673
Botulinum Toxin Injections for Masseter Reduction in East Asians.
Cheng J, Hsu SH, McGee JS
Dermatol Surg 2019 Apr;45(4):566-572. doi: 10.1097/DSS.0000000000001859. PMID: 30883483
Association between signs and symptoms of bruxism and presence of tori: a systematic review.
Bertazzo-Silveira E, Stuginski-Barbosa J, Porporatti AL, Dick B, Flores-Mir C, Manfredini D, De Luca Canto G
Clin Oral Investig 2017 Dec;21(9):2789-2799. Epub 2017 Feb 17 doi: 10.1007/s00784-017-2081-7. PMID: 28213765
Mandibular angloplasty.
Kim HC, Kameyama T
Kurume Med J 1992;39(3):147-51. doi: 10.2739/kurumemedj.39.147. PMID: 1491548

Therapy

Botulinum Toxin for Treating Temporomandibular Disorders: What is the Evidence?
Delcanho R, Val M, Guarda Nardini L, Manfredini D
J Oral Facial Pain Headache 2022 Winter;36(1):6-20. doi: 10.11607/ofph.3023. PMID: 35298571Free PMC Article
Alternative Clinical Indications of Botulinum Toxin.
Alster TS, Harrison IS
Am J Clin Dermatol 2020 Dec;21(6):855-880. doi: 10.1007/s40257-020-00532-0. PMID: 32651806
Overview of Botulinum Toxins for Aesthetic Uses.
Gart MS, Gutowski KA
Clin Plast Surg 2016 Jul;43(3):459-71. Epub 2016 May 4 doi: 10.1016/j.cps.2016.03.003. PMID: 27363760
Bilateral hypertrophy of masseteric and temporalis muscles, our fifteen patients and review of literature.
Graziano P, Dell'Aversana Orabona G, Astarita F, Ponzo LM, Nunziata R, Salzano G, Maglitto F, Solari D, Santella A, Cappabianca M, Iaconetta G, Califano L
Eur Rev Med Pharmacol Sci 2016;20(1):7-11. PMID: 26813447
Botulinum toxin for masseter hypertrophy.
Fedorowicz Z, van Zuuren EJ, Schoones J
Cochrane Database Syst Rev 2013 Sep 9;2013(9):CD007510. doi: 10.1002/14651858.CD007510.pub3. PMID: 24018587Free PMC Article

Prognosis

Niemann-Pick type A disease with new mutation: a case report.
Aghamahdi F, Nirouei M, Savad S
J Med Case Rep 2022 Jul 27;16(1):288. doi: 10.1186/s13256-022-03486-5. PMID: 35883096Free PMC Article
Somatic GNAQ mutation in different structures of port-wine macrocheilia.
Ma G, Yu Z, Liu F, Wang L, Yu W, Zhu J, Gu H, Liu Y, Cai R, Lin X
Br J Dermatol 2018 Nov;179(5):1109-1114. Epub 2018 Aug 14 doi: 10.1111/bjd.16830. PMID: 29878304
Muscular and functional changes following adenotonsillectomy in children.
Bueno Dde A, Grechi TH, Trawitzki LV, Anselmo-Lima WT, Felício CM, Valera FC
Int J Pediatr Otorhinolaryngol 2015 Apr;79(4):537-40. Epub 2015 Jan 28 doi: 10.1016/j.ijporl.2015.01.024. PMID: 25669724
Temporalis muscle hypertrophy and reduced skull eccentricity in Duchenne muscular dystrophy.
Straathof CS, Doorenweerd N, Wokke BH, Dumas EM, van den Bergen JC, van Buchem MA, Hendriksen JG, Verschuuren JJ, Kan HE
J Child Neurol 2014 Oct;29(10):1344-8. Epub 2014 Mar 19 doi: 10.1177/0883073813518106. PMID: 24646504
A review of the current uses of Botox for dentally-related procedures.
Bhogal PS, Hutton A, Monaghan A
Dent Update 2006 Apr;33(3):165-8. doi: 10.12968/denu.2006.33.3.165. PMID: 16700273

Clinical prediction guides

Exploring botulinum toxin's impact on masseter hypertrophy: a randomized, triple-blinded clinical trial.
de Souza Nobre BB, Rezende L, Barbosa Câmara-Souza M, Sanchez-Ayala A, Blass R, Carbone AC, Manso AC, Ernberg M, Christidis N, De la Torre Canales G
Sci Rep 2024 Jun 24;14(1):14522. doi: 10.1038/s41598-024-65395-5. PMID: 38914688Free PMC Article
Concurrent fabry disease and immunoglobulin a nephropathy: a case report.
Zhou LN, Dong SS, Zhang SZ, Huang LW, Huang W
BMC Nephrol 2023 Nov 1;24(1):324. doi: 10.1186/s12882-023-03282-3. PMID: 37914990Free PMC Article
Orbicularis Oculi Muscle Immunohistochemical, Metabolic, and Morphometric Differences in Affected and Nonaffected Sides in Hemifacial Spasm vs Healthy Subjects.
Osaki TH, Gameiro GR, Osaki MH, Osaki T, Campos ED, Belfort R Jr, Marie SKN
J Neuroophthalmol 2023 Sep 1;43(3):410-416. Epub 2022 Nov 25 doi: 10.1097/WNO.0000000000001770. PMID: 36730142
Gravitational forces, negative pressure and facial structure in the genesis of airway dysfunction during sleep: a review of the paradigm.
Stupak HD, Park SY
Sleep Med 2018 Nov;51:125-132. Epub 2018 Jul 6 doi: 10.1016/j.sleep.2018.06.016. PMID: 30165336
Association between signs and symptoms of bruxism and presence of tori: a systematic review.
Bertazzo-Silveira E, Stuginski-Barbosa J, Porporatti AL, Dick B, Flores-Mir C, Manfredini D, De Luca Canto G
Clin Oral Investig 2017 Dec;21(9):2789-2799. Epub 2017 Feb 17 doi: 10.1007/s00784-017-2081-7. PMID: 28213765

Recent systematic reviews

Systematic review of the histological and functional effects of botulinum toxin A on masticatory muscles: Consideration in dentofacial orthopedics and orthognathic surgery.
Guignardat JF, Raoul G, Ferri J, Sciote JJ, Nicot R
Ann Anat 2024 Oct;256:152302. Epub 2024 Jul 20 doi: 10.1016/j.aanat.2024.152302. PMID: 39038690
Association between signs and symptoms of bruxism and presence of tori: a systematic review.
Bertazzo-Silveira E, Stuginski-Barbosa J, Porporatti AL, Dick B, Flores-Mir C, Manfredini D, De Luca Canto G
Clin Oral Investig 2017 Dec;21(9):2789-2799. Epub 2017 Feb 17 doi: 10.1007/s00784-017-2081-7. PMID: 28213765
Botulinum toxin for masseter hypertrophy.
Fedorowicz Z, van Zuuren EJ, Schoones J
Cochrane Database Syst Rev 2013 Sep 9;2013(9):CD007510. doi: 10.1002/14651858.CD007510.pub3. PMID: 24018587Free PMC Article
Botulinum toxin for masseter hypertrophy.
Al-Muharraqi MA, Fedorowicz Z, Al Bareeq J, Al Bareeq R, Nasser M
Cochrane Database Syst Rev 2009 Jan 21;(1):CD007510. doi: 10.1002/14651858.CD007510.pub2. PMID: 19160335

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