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Increased activity of mitochondrial respiratory chain

MedGen UID:
868100
Concept ID:
C4022491
Finding
HPO: HP:0040015

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased activity of mitochondrial respiratory chain

Professional guidelines

PubMed

Duberley KE, Abramov AY, Chalasani A, Heales SJ, Rahman S, Hargreaves IP
J Inherit Metab Dis 2013 Jan;36(1):63-73. Epub 2012 Jul 6 doi: 10.1007/s10545-012-9511-0. PMID: 22767283

Recent clinical studies

Etiology

Xue Q, Kang R, Klionsky DJ, Tang D, Liu J, Chen X
Autophagy 2023 Aug;19(8):2175-2195. Epub 2023 Apr 16 doi: 10.1080/15548627.2023.2200554. PMID: 37055935Free PMC Article
He L, Wang J, Yang Y, Li J, Tu H
Neurochem Res 2022 Jun;47(6):1491-1502. Epub 2022 Feb 26 doi: 10.1007/s11064-022-03560-w. PMID: 35220492
Zhang B, Pan C, Feng C, Yan C, Yu Y, Chen Z, Guo C, Wang X
Redox Rep 2022 Dec;27(1):45-52. doi: 10.1080/13510002.2022.2046423. PMID: 35213291Free PMC Article
Wang T, Li C, Han B, Wang Z, Meng X, Zhang L, He J, Fu F
BMC Complement Med Ther 2020 Jan 23;20(1):20. doi: 10.1186/s12906-019-2738-7. PMID: 32020857Free PMC Article
Shah MS, Brownlee M
Circ Res 2016 May 27;118(11):1808-29. doi: 10.1161/CIRCRESAHA.116.306923. PMID: 27230643Free PMC Article

Diagnosis

Xue Q, Kang R, Klionsky DJ, Tang D, Liu J, Chen X
Autophagy 2023 Aug;19(8):2175-2195. Epub 2023 Apr 16 doi: 10.1080/15548627.2023.2200554. PMID: 37055935Free PMC Article
López-Grueso MJ, Lagal DJ, García-Jiménez ÁF, Tarradas RM, Carmona-Hidalgo B, Peinado J, Requejo-Aguilar R, Bárcena JA, Padilla CA
Redox Biol 2020 Oct;37:101737. Epub 2020 Sep 29 doi: 10.1016/j.redox.2020.101737. PMID: 33035814Free PMC Article
Franco-Iborra S, Tanji K
Methods Cell Biol 2020;155:247-270. Epub 2020 Jan 20 doi: 10.1016/bs.mcb.2019.11.024. PMID: 32183961
Chen Z, Tian R, She Z, Cai J, Li H
Free Radic Biol Med 2020 May 20;152:116-141. Epub 2020 Mar 8 doi: 10.1016/j.freeradbiomed.2020.02.025. PMID: 32156524
Chistiakov DA, Shkurat TP, Melnichenko AA, Grechko AV, Orekhov AN
Ann Med 2018 Mar;50(2):121-127. Epub 2017 Dec 18 doi: 10.1080/07853890.2017.1417631. PMID: 29237304

Therapy

Padilla J, Lee J
Cells 2021 Mar 12;10(3) doi: 10.3390/cells10030634. PMID: 33809182Free PMC Article
Krall AS, Mullen PJ, Surjono F, Momcilovic M, Schmid EW, Halbrook CJ, Thambundit A, Mittelman SD, Lyssiotis CA, Shackelford DB, Knott SRV, Christofk HR
Cell Metab 2021 May 4;33(5):1013-1026.e6. Epub 2021 Feb 19 doi: 10.1016/j.cmet.2021.02.001. PMID: 33609439Free PMC Article
Raggi C, Taddei ML, Sacco E, Navari N, Correnti M, Piombanti B, Pastore M, Campani C, Pranzini E, Iorio J, Lori G, Lottini T, Peano C, Cibella J, Lewinska M, Andersen JB, di Tommaso L, Viganò L, Di Maira G, Madiai S, Ramazzotti M, Orlandi I, Arcangeli A, Chiarugi P, Marra F
J Hepatol 2021 Jun;74(6):1373-1385. Epub 2021 Jan 21 doi: 10.1016/j.jhep.2020.12.031. PMID: 33484774
Hallakou-Bozec S, Vial G, Kergoat M, Fouqueray P, Bolze S, Borel AL, Fontaine E, Moller DE
Diabetes Obes Metab 2021 Mar;23(3):664-673. Epub 2020 Dec 29 doi: 10.1111/dom.14277. PMID: 33269554Free PMC Article
Wang M, Zhang Y, Xu M, Zhang H, Chen Y, Chung KF, Adcock IM, Li F
Free Radic Biol Med 2019 Apr;134:229-238. Epub 2019 Jan 9 doi: 10.1016/j.freeradbiomed.2019.01.004. PMID: 30639616

Prognosis

Liu JF, Peng WJ, Wu Y, Yang YH, Wu SF, Liu DP, Liu JN, Yang JT
EBioMedicine 2023 Apr;90:104518. Epub 2023 Mar 16 doi: 10.1016/j.ebiom.2023.104518. PMID: 36933413Free PMC Article
Ito A, Hashimoto M, Tanihata J, Matsubayashi S, Sasaki R, Fujimoto S, Kawamoto H, Hosaka Y, Ichikawa A, Kadota T, Fujita Y, Takekoshi D, Ito S, Minagawa S, Numata T, Hara H, Matsuoka T, Udaka J, Araya J, Saito M, Kuwano K
J Cachexia Sarcopenia Muscle 2022 Jun;13(3):1864-1882. Epub 2022 Apr 3 doi: 10.1002/jcsm.12988. PMID: 35373498Free PMC Article
Krall AS, Mullen PJ, Surjono F, Momcilovic M, Schmid EW, Halbrook CJ, Thambundit A, Mittelman SD, Lyssiotis CA, Shackelford DB, Knott SRV, Christofk HR
Cell Metab 2021 May 4;33(5):1013-1026.e6. Epub 2021 Feb 19 doi: 10.1016/j.cmet.2021.02.001. PMID: 33609439Free PMC Article
Raggi C, Taddei ML, Sacco E, Navari N, Correnti M, Piombanti B, Pastore M, Campani C, Pranzini E, Iorio J, Lori G, Lottini T, Peano C, Cibella J, Lewinska M, Andersen JB, di Tommaso L, Viganò L, Di Maira G, Madiai S, Ramazzotti M, Orlandi I, Arcangeli A, Chiarugi P, Marra F
J Hepatol 2021 Jun;74(6):1373-1385. Epub 2021 Jan 21 doi: 10.1016/j.jhep.2020.12.031. PMID: 33484774
Brown DA, Perry JB, Allen ME, Sabbah HN, Stauffer BL, Shaikh SR, Cleland JG, Colucci WS, Butler J, Voors AA, Anker SD, Pitt B, Pieske B, Filippatos G, Greene SJ, Gheorghiade M
Nat Rev Cardiol 2017 Apr;14(4):238-250. Epub 2016 Dec 22 doi: 10.1038/nrcardio.2016.203. PMID: 28004807Free PMC Article

Clinical prediction guides

Walker MA, Chen H, Yadav A, Ritterhoff J, Villet O, McMillen T, Wang Y, Purcell H, Djukovic D, Raftery D, Isoherranen N, Tian R
Circulation 2023 Dec 19;148(25):2038-2057. Epub 2023 Nov 15 doi: 10.1161/CIRCULATIONAHA.123.066039. PMID: 37965787Free PMC Article
Fernström J, Mellon SH, McGill MA, Picard M, Reus VI, Hough CM, Lin J, Epel ES, Wolkowitz OM, Lindqvist D
Transl Psychiatry 2021 Nov 17;11(1):593. doi: 10.1038/s41398-021-01723-x. PMID: 34789750Free PMC Article
Bjork JA, Wallace KB
Toxicol Appl Pharmacol 2021 Dec 15;433:115783. Epub 2021 Nov 2 doi: 10.1016/j.taap.2021.115783. PMID: 34740633Free PMC Article
Ale-Agha N, Jakobs P, Goy C, Zurek M, Rosen J, Dyballa-Rukes N, Metzger S, Greulich J, von Ameln F, Eckermann O, Unfried K, Brack F, Grandoch M, Thielmann M, Kamler M, Gedik N, Kleinbongard P, Heinen A, Heusch G, Gödecke A, Altschmied J, Haendeler J
Circulation 2021 Dec 7;144(23):1876-1890. Epub 2021 Oct 21 doi: 10.1161/CIRCULATIONAHA.120.051923. PMID: 34672678
Mansouri A, Gattolliat CH, Asselah T
Gastroenterology 2018 Sep;155(3):629-647. Epub 2018 Aug 2 doi: 10.1053/j.gastro.2018.06.083. PMID: 30012333

Recent systematic reviews

Beyfuss K, Hood DA
Redox Rep 2018 Dec;23(1):100-117. Epub 2018 Jan 3 doi: 10.1080/13510002.2017.1416773. PMID: 29298131Free PMC Article

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