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Adult Pleomorphic Hepatocellular Carcinoma

MedGen UID:
859689
Concept ID:
C3900095
Neoplastic Process

Definition

A pleomorphic hepatocellular carcinoma that occurs during adulthood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult Pleomorphic Hepatocellular Carcinoma

Recent clinical studies

Etiology

Sumazin P, Peters TL, Sarabia SF, Kim HR, Urbicain M, Hollingsworth EF, Alvarez KR, Perez CR, Pozza A, Najaf Panah MJ, Epps JL, Scorsone K, Zorman B, Katzenstein H, O'Neill AF, Meyers R, Tiao G, Geller J, Ranganathan S, Rangaswami AA, Woodfield SE, Goss JA, Vasudevan SA, Heczey A, Roy A, Fisher KE, Alaggio R, Patel KR, Finegold MJ, López-Terrada DH
J Hepatol 2022 Oct;77(4):1026-1037. Epub 2022 May 14 doi: 10.1016/j.jhep.2022.04.035. PMID: 35577029Free PMC Article
Morisue R, Kojima M, Suzuki T, Nakatsura T, Ojima H, Watanabe R, Sugimoto M, Kobayashi S, Takahashi S, Konishi M, Ishii G, Gotohda N, Fujiwara T, Ochiai A
Int J Cancer 2021 Aug 1;149(3):546-560. Epub 2021 Mar 13 doi: 10.1002/ijc.33545. PMID: 33662146
Rastogi A, Maiwall R, Ramakrishna G, Modi S, Taneja K, Bihari C, Kumar G, Patil N, Thapar S, Choudhury AK, Mukund A, Pamecha V, Sarin SK
Pathol Res Pract 2021 Jan;217:153290. Epub 2020 Nov 24 doi: 10.1016/j.prp.2020.153290. PMID: 33307344
Calderaro J, Couchy G, Imbeaud S, Amaddeo G, Letouzé E, Blanc JF, Laurent C, Hajji Y, Azoulay D, Bioulac-Sage P, Nault JC, Zucman-Rossi J
J Hepatol 2017 Oct;67(4):727-738. Epub 2017 May 19 doi: 10.1016/j.jhep.2017.05.014. PMID: 28532995
Guzman G, Chennuri R, Chan A, Rea B, Quintana A, Patel R, Xu PZ, Xie H, Hay N
Dig Dis Sci 2015 Feb;60(2):420-6. Epub 2014 Nov 8 doi: 10.1007/s10620-014-3364-3. PMID: 25381201Free PMC Article

Diagnosis

Sumazin P, Peters TL, Sarabia SF, Kim HR, Urbicain M, Hollingsworth EF, Alvarez KR, Perez CR, Pozza A, Najaf Panah MJ, Epps JL, Scorsone K, Zorman B, Katzenstein H, O'Neill AF, Meyers R, Tiao G, Geller J, Ranganathan S, Rangaswami AA, Woodfield SE, Goss JA, Vasudevan SA, Heczey A, Roy A, Fisher KE, Alaggio R, Patel KR, Finegold MJ, López-Terrada DH
J Hepatol 2022 Oct;77(4):1026-1037. Epub 2022 May 14 doi: 10.1016/j.jhep.2022.04.035. PMID: 35577029Free PMC Article
Chen J, Wan X, Lu Y, Wang W, Zhao D, Lu Z, Mao Y, Chen J
Diagn Pathol 2021 Jul 4;16(1):58. doi: 10.1186/s13000-021-01097-0. PMID: 34218806Free PMC Article
Chen TY, Lorch JH, Wong KS, Barletta JA
Histopathology 2020 Aug;77(2):314-320. Epub 2020 Jul 23 doi: 10.1111/his.14144. PMID: 32428249
Lai YS, Cheng CC, Lee MT, Chao WT, Lai YC, Hsu YH, Liu YH
Int J Med Sci 2018;15(14):1746-1756. Epub 2018 Nov 23 doi: 10.7150/ijms.28440. PMID: 30588199Free PMC Article
Lampri ES, Ioachim E, Harissis H, Balasi E, Mitselou A, Malamou-Mitsi V
World J Gastroenterol 2014 Feb 28;20(8):2113-6. doi: 10.3748/wjg.v20.i8.2113. PMID: 24587684Free PMC Article

Therapy

Morisue R, Kojima M, Suzuki T, Nakatsura T, Ojima H, Watanabe R, Sugimoto M, Kobayashi S, Takahashi S, Konishi M, Ishii G, Gotohda N, Fujiwara T, Ochiai A
Int J Cancer 2021 Aug 1;149(3):546-560. Epub 2021 Mar 13 doi: 10.1002/ijc.33545. PMID: 33662146
Hu W, Zheng S, Guo H, Dai B, Ni J, Shi Y, Bian H, Li L, Shen Y, Wu M, Tian Z, Liu G, Hossain MA, Yang H, Wang D, Zhang Q, Yu J, Birnbaumer L, Feng J, Yu D, Yang Y
Hepatology 2021 Feb;73(2):674-691. Epub 2021 Feb 6 doi: 10.1002/hep.31293. PMID: 32335942
Tahir Z, Peters J, Leahy K, Batalini F
BMJ Case Rep 2020 Jan 2;13(1) doi: 10.1136/bcr-2019-231831. PMID: 31900295Free PMC Article
Lampri ES, Ioachim E, Harissis H, Balasi E, Mitselou A, Malamou-Mitsi V
World J Gastroenterol 2014 Feb 28;20(8):2113-6. doi: 10.3748/wjg.v20.i8.2113. PMID: 24587684Free PMC Article
Tao LC
Cancer 1991 Jul 15;68(2):341-7. doi: 10.1002/1097-0142(19910715)68:2<341::aid-cncr2820680223>3.0.co;2-q. PMID: 1712664

Prognosis

Morisue R, Kojima M, Suzuki T, Nakatsura T, Ojima H, Watanabe R, Sugimoto M, Kobayashi S, Takahashi S, Konishi M, Ishii G, Gotohda N, Fujiwara T, Ochiai A
Int J Cancer 2021 Aug 1;149(3):546-560. Epub 2021 Mar 13 doi: 10.1002/ijc.33545. PMID: 33662146
Chen TY, Lorch JH, Wong KS, Barletta JA
Histopathology 2020 Aug;77(2):314-320. Epub 2020 Jul 23 doi: 10.1111/his.14144. PMID: 32428249
Lai YS, Cheng CC, Lee MT, Chao WT, Lai YC, Hsu YH, Liu YH
Int J Med Sci 2018;15(14):1746-1756. Epub 2018 Nov 23 doi: 10.7150/ijms.28440. PMID: 30588199Free PMC Article
Liu JH, Tsai HL, Hsu SM, Hu DH, Chen SS
Kaohsiung J Med Sci 2004 Feb;20(2):78-82. doi: 10.1016/S1607-551X(09)70088-9. PMID: 15481555
Moore SW, Hesseling PB, Wessels G, Schneider JW
Pediatr Surg Int 1997 Apr;12(4):266-70. doi: 10.1007/BF01372147. PMID: 9099643

Clinical prediction guides

Sumazin P, Peters TL, Sarabia SF, Kim HR, Urbicain M, Hollingsworth EF, Alvarez KR, Perez CR, Pozza A, Najaf Panah MJ, Epps JL, Scorsone K, Zorman B, Katzenstein H, O'Neill AF, Meyers R, Tiao G, Geller J, Ranganathan S, Rangaswami AA, Woodfield SE, Goss JA, Vasudevan SA, Heczey A, Roy A, Fisher KE, Alaggio R, Patel KR, Finegold MJ, López-Terrada DH
J Hepatol 2022 Oct;77(4):1026-1037. Epub 2022 May 14 doi: 10.1016/j.jhep.2022.04.035. PMID: 35577029Free PMC Article
Chen TY, Lorch JH, Wong KS, Barletta JA
Histopathology 2020 Aug;77(2):314-320. Epub 2020 Jul 23 doi: 10.1111/his.14144. PMID: 32428249
Hu ZY, Yuan SX, Yang Y, Zhou WP, Jiang H
J Exp Clin Cancer Res 2014 Jul 25;33(1):61. doi: 10.1186/s13046-014-0061-1. PMID: 25060425Free PMC Article
Ishiwata I, Yasuda M, Hirano T, Ishikawa H
Hum Cell 2007 Nov;20(4):119-30. doi: 10.1111/j.1749-0774.2007.00039.x. PMID: 17949352
Lauwers GY, Terris B, Balis UJ, Batts KP, Regimbeau JM, Chang Y, Graeme-Cook F, Yamabe H, Ikai I, Cleary KR, Fujita S, Flejou JF, Zukerberg LR, Nagorney DM, Belghiti J, Yamaoka Y, Vauthey JN; International Cooperative Study Group on Hepatocellular Carcinoma
Am J Surg Pathol 2002 Jan;26(1):25-34. doi: 10.1097/00000478-200201000-00003. PMID: 11756766

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