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Malignant Biliary Obstruction

MedGen UID:
858067
•Concept ID:
C3898473
•
Disease or Syndrome

Definition

Blockage in the biliary tract caused by a malignant neoplasm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Biliary Obstruction

Professional guidelines

PubMed

Evaluation and Management of Malignant Biliary Obstruction.
Guardado NV, Llorente K, Blondeau B
Surg Oncol Clin N Am 2021 Jul;30(3):491-503. doi: 10.1016/j.soc.2021.03.001. PMID: 34053664
Percutaneous management of malignant biliary disease.
Riaz A, Pinkard JP, Salem R, Lewandowski RJ
J Surg Oncol 2019 Jul;120(1):45-56. Epub 2019 Apr 12 doi: 10.1002/jso.25471. PMID: 30977913
Endoscopic biliary stenting: indications, choice of stents, and results: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline - Updated October 2017.
Dumonceau JM, Tringali A, Papanikolaou IS, Blero D, Mangiavillano B, Schmidt A, Vanbiervliet G, Costamagna G, Devière J, García-Cano J, Gyökeres T, Hassan C, Prat F, Siersema PD, van Hooft JE
Endoscopy 2018 Sep;50(9):910-930. Epub 2018 Aug 7 doi: 10.1055/a-0659-9864. PMID: 30086596

Recent clinical studies

Etiology

Endoscopic Management of Malignant Biliary Obstruction.
Paik WH, Park DH
Gastrointest Endosc Clin N Am 2024 Jan;34(1):127-140. Epub 2023 Aug 28 doi: 10.1016/j.giec.2023.07.004. PMID: 37973224
Endoluminal radiofrequency ablation in patients with malignant biliary obstruction: a randomised trial.
Jarosova J, Zarivnijova L, Cibulkova I, Mares J, Macinga P, Hujova A, Falt P, Urban O, Hajer J, Spicak J, Hucl T
Gut 2023 Nov 24;72(12):2286-2293. doi: 10.1136/gutjnl-2023-329700. PMID: 37652677
ePTFE/FEP stents for malignant biliary obstruction.
Hui A, Krokidis M
BMJ Support Palliat Care 2022 Jul;12(e2):e174-e177. Epub 2020 Feb 13 doi: 10.1136/bmjspcare-2019-001961. PMID: 32054643
Biliary stenting for hilar malignant biliary obstruction.
Lee TH, Moon JH, Park SH
Dig Endosc 2020 Jan;32(2):275-286. Epub 2019 Dec 18 doi: 10.1111/den.13549. PMID: 31578770
Percutaneous Management of Malignant Biliary Obstruction.
Sutter CM, Ryu RK
Tech Vasc Interv Radiol 2015 Dec;18(4):218-26. Epub 2015 Jul 15 doi: 10.1053/j.tvir.2015.07.005. PMID: 26615162

Diagnosis

Malignant biliary obstruction due to metastatic non-hepato-pancreato-biliary cancer.
Okamoto T
World J Gastroenterol 2022 Mar 14;28(10):985-1008. doi: 10.3748/wjg.v28.i10.985. PMID: 35431494Free PMC Article
Evaluation and Management of Malignant Biliary Obstruction.
Guardado NV, Llorente K, Blondeau B
Surg Oncol Clin N Am 2021 Jul;30(3):491-503. doi: 10.1016/j.soc.2021.03.001. PMID: 34053664
Management of distal malignant biliary obstruction.
Aljahdli ES
Saudi J Gastroenterol 2018 Mar-Apr;24(2):71-72. doi: 10.4103/sjg.SJG_611_17. PMID: 29637911Free PMC Article
Endoscopic Management of Pancreatobiliary Neoplasms.
Wang AY, Yachimski PS
Gastroenterology 2018 May;154(7):1947-1963. Epub 2018 Feb 16 doi: 10.1053/j.gastro.2017.11.295. PMID: 29458151
The endoscopist and malignant and non-malignant biliary obstruction.
Pereira SP, Goodchild G, Webster GJM
Biochim Biophys Acta Mol Basis Dis 2018 Apr;1864(4 Pt B):1478-1483. Epub 2017 Sep 18 doi: 10.1016/j.bbadis.2017.09.013. PMID: 28931489Free PMC Article

Therapy

Endoscopic ultrasound-guided biliary interventions.
Madhu D, Dhir V
Indian J Gastroenterol 2024 Oct;43(5):943-953. Epub 2024 Sep 11 doi: 10.1007/s12664-024-01680-5. PMID: 39259450
Endoluminal radiofrequency ablation in patients with malignant biliary obstruction: a randomised trial.
Jarosova J, Zarivnijova L, Cibulkova I, Mares J, Macinga P, Hujova A, Falt P, Urban O, Hajer J, Spicak J, Hucl T
Gut 2023 Nov 24;72(12):2286-2293. doi: 10.1136/gutjnl-2023-329700. PMID: 37652677
Malignant biliary obstruction due to metastatic non-hepato-pancreato-biliary cancer.
Okamoto T
World J Gastroenterol 2022 Mar 14;28(10):985-1008. doi: 10.3748/wjg.v28.i10.985. PMID: 35431494Free PMC Article
ePTFE/FEP stents for malignant biliary obstruction.
Hui A, Krokidis M
BMJ Support Palliat Care 2022 Jul;12(e2):e174-e177. Epub 2020 Feb 13 doi: 10.1136/bmjspcare-2019-001961. PMID: 32054643
Stenting for Benign and Malignant Biliary Strictures.
Bill JG, Mullady DK
Gastrointest Endosc Clin N Am 2019 Apr;29(2):215-235. Epub 2019 Jan 23 doi: 10.1016/j.giec.2018.12.001. PMID: 30846150

Prognosis

Biliary stenting for hilar malignant biliary obstruction.
Lee TH, Moon JH, Park SH
Dig Endosc 2020 Jan;32(2):275-286. Epub 2019 Dec 18 doi: 10.1111/den.13549. PMID: 31578770
Endoscopic Management of Pancreatobiliary Neoplasms.
Wang AY, Yachimski PS
Gastroenterology 2018 May;154(7):1947-1963. Epub 2018 Feb 16 doi: 10.1053/j.gastro.2017.11.295. PMID: 29458151
Endoscopic management of combined malignant biliary and gastric outlet obstruction.
Nakai Y, Hamada T, Isayama H, Itoi T, Koike K
Dig Endosc 2017 Jan;29(1):16-25. Epub 2016 Sep 13 doi: 10.1111/den.12729. PMID: 27552727
Percutaneous Management of Malignant Biliary Obstruction.
Sutter CM, Ryu RK
Tech Vasc Interv Radiol 2015 Dec;18(4):218-26. Epub 2015 Jul 15 doi: 10.1053/j.tvir.2015.07.005. PMID: 26615162
Endoscopic ultrasound-guided biliary drainage of hilar biliary obstruction.
Park DH
J Hepatobiliary Pancreat Sci 2015 Sep;22(9):664-8. Epub 2015 Jul 15 doi: 10.1002/jhbp.271. PMID: 26178753

Clinical prediction guides

Long-term outcomes of endoscopic ultrasound-guided hepaticogastrostomy in patients with malignant biliary obstruction.
Hedjoudje A, Pokossy Epée J, Perez-Cuadrado-Robles E, Alric H, Rivallin P, Vuitton L, Koch S, Prat F
United European Gastroenterol J 2024 Oct;12(8):1044-1055. Epub 2024 Apr 5 doi: 10.1002/ueg2.12552. PMID: 38578654Free PMC Article
Risk factors for biliary stent infections in malignant biliary obstruction secondary to unresectable malignancies.
Petit S, Puyade M, Pichon M, Wangermez M, Velasco S, Roblot F, Isambert N, Evrard C, Rammaert B
Support Care Cancer 2022 Aug;30(8):6937-6946. Epub 2022 May 11 doi: 10.1007/s00520-022-07106-2. PMID: 35543817
ePTFE/FEP stents for malignant biliary obstruction.
Hui A, Krokidis M
BMJ Support Palliat Care 2022 Jul;12(e2):e174-e177. Epub 2020 Feb 13 doi: 10.1136/bmjspcare-2019-001961. PMID: 32054643
Percutaneous Management of Malignant Biliary Obstruction.
Sutter CM, Ryu RK
Tech Vasc Interv Radiol 2015 Dec;18(4):218-26. Epub 2015 Jul 15 doi: 10.1053/j.tvir.2015.07.005. PMID: 26615162
Metal versus plastic stents for malignant biliary obstruction: an update meta-analysis.
Hong WD, Chen XW, Wu WZ, Zhu QH, Chen XR
Clin Res Hepatol Gastroenterol 2013 Nov;37(5):496-500. Epub 2013 Jan 18 doi: 10.1016/j.clinre.2012.12.002. PMID: 23333231

Recent systematic reviews

EUS- versus ERCP-guided biliary drainage for malignant biliary obstruction: a systematic review and meta-analysis of randomized controlled trials.
Barbosa EC, Santo PADE, Baraldo S, Nau AL, Meine GC
Gastrointest Endosc 2024 Sep;100(3):395-405.e8. Epub 2024 Apr 20 doi: 10.1016/j.gie.2024.04.019. PMID: 38648989
Efficacy and safety of endoscopic ultrasound-guided hepaticogastrostomy: a meta-regression analysis.
Binda C, Dajti E, Giuffrida P, Trebbi M, Coluccio C, Cucchetti A, Fugazza A, Perini B, Gibiino G, Anderloni A, Repici A, Fabbri C
Endoscopy 2024 Sep;56(9):694-705. Epub 2024 Mar 6 doi: 10.1055/a-2282-3350. PMID: 38447958
Fully covered versus partially covered self-expandable metal stents for palliation of distal malignant biliary obstruction: a systematic review and meta-analysis.
Vanella G, Coluccio C, Cucchetti A, Leone R, Dell'Anna G, Giuffrida P, Abbatiello C, Binda C, Fabbri C, Arcidiacono PG
Gastrointest Endosc 2024 Mar;99(3):314-322.e19. Epub 2023 Oct 7 doi: 10.1016/j.gie.2023.10.023. PMID: 37813199
Comparison of Biliary Drainage Techniques for Malignant Biliary Obstruction: A Systematic Review and Network Meta-analysis.
Xie J, Garg S, Perisetti A, Tharian B, Murad MH, Inamdar S
J Clin Gastroenterol 2022 Jan 1;56(1):88-97. doi: 10.1097/MCG.0000000000001512. PMID: 33780212
Endoscopic stenting for inoperable malignant biliary obstruction: A systematic review and meta-analysis.
Zorrón Pu L, de Moura EG, Bernardo WM, Baracat FI, Mendonça EQ, Kondo A, Luz GO, Furuya Júnior CK, Artifon EL
World J Gastroenterol 2015 Dec 21;21(47):13374-85. doi: 10.3748/wjg.v21.i47.13374. PMID: 26715823Free PMC Article

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