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Mild Bronchopulmonary Dysplasia

MedGen UID:
857946
Concept ID:
C3898352
Disease or Syndrome

Definition

A chronic lung disorder associated with pulmonary maldevelopment, scarring, and/or inflammation that develops in preterm neonates exposed to supplemental oxygen for at least 28 days. For infants born before 32 weeks gestation with mild BPD, there is no supplemental oxygen requirement at 36 weeks postmenstrual age or earlier discharge. For infants born after 32 weeks with mild BPD, there is no supplemental oxygen requirement at 56 days post-natal age or at earlier discharge. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMild Bronchopulmonary Dysplasia

Professional guidelines

PubMed

Beasley E, Megerian G, Gerson A, Roberts NS
Obstet Gynecol 1999 Jan;93(1):130-4. doi: 10.1016/s0029-7844(98)00399-8. PMID: 9916970

Recent clinical studies

Etiology

Bokiniec R, Własienko P, Borszewska-Kornacka M, Szymkiewicz-Dangel J
Echocardiography 2017 Apr;34(4):567-576. Epub 2017 Mar 31 doi: 10.1111/echo.13488. PMID: 28370301
Bokiniec R, Własienko P, Borszewska-Kornacka M, Szymkiewicz-Dangel J
Echocardiography 2017 Apr;34(4):577-586. Epub 2017 Feb 23 doi: 10.1111/echo.13489. PMID: 28229480
MacLean JE, DeHaan K, Fuhr D, Hariharan S, Kamstra B, Hendson L, Adatia I, Majaesic C, Lovering AT, Thompson RB, Nicholas D, Thebaud B, Stickland MK
Thorax 2016 Nov;71(11):1012-1019. Epub 2016 Jun 3 doi: 10.1136/thoraxjnl-2015-207736. PMID: 27259338Free PMC Article
Fukunaga S, Ichiyama T, Maeba S, Okuda M, Nakata M, Sugino N, Furukawa S
Pediatr Pulmonol 2009 Mar;44(3):267-72. doi: 10.1002/ppul.20993. PMID: 19205055
Streubel AH, Donohue PK, Aucott SW
J Perinatol 2008 Feb;28(2):141-8. Epub 2007 Dec 6 doi: 10.1038/sj.jp.7211894. PMID: 18059466

Diagnosis

Stoecklin B, Choi YJ, Rakshasbhuvankar A, Svedenkrans J, Jones G, Pillow J
Thorax 2021 Jul;76(7):689-695. Epub 2021 Feb 11 doi: 10.1136/thoraxjnl-2020-214659. PMID: 33574124
Bokiniec R, Własienko P, Borszewska-Kornacka M, Szymkiewicz-Dangel J
Echocardiography 2017 Apr;34(4):567-576. Epub 2017 Mar 31 doi: 10.1111/echo.13488. PMID: 28370301
Fukunaga S, Ichiyama T, Maeba S, Okuda M, Nakata M, Sugino N, Furukawa S
Pediatr Pulmonol 2009 Mar;44(3):267-72. doi: 10.1002/ppul.20993. PMID: 19205055
Poets CF, Meny RG, Chobanian MR, Bonofiglo RE
Pediatr Res 1999 Mar;45(3):350-4. doi: 10.1203/00006450-199903000-00010. PMID: 10088653
Boynton BR, Mannino FL, Davis RF, Kopotic RJ, Friederichsen G
J Pediatr 1984 Aug;105(2):297-302. doi: 10.1016/s0022-3476(84)80136-5. PMID: 6379137

Therapy

Biermayr M, Brunner B, Maurer K, Trawoeger R, Kiechl-Kohlendorfer U, Neubauer V
BMC Pediatr 2016 Sep 6;16(1):154. doi: 10.1186/s12887-016-0691-x. PMID: 27599834Free PMC Article
Streubel AH, Donohue PK, Aucott SW
J Perinatol 2008 Feb;28(2):141-8. Epub 2007 Dec 6 doi: 10.1038/sj.jp.7211894. PMID: 18059466
Chessex P, Bélanger S, Piedboeuf B, Pineault M
J Pediatr 1995 Apr;126(4):619-24. doi: 10.1016/s0022-3476(95)70364-0. PMID: 7699545
Shen-Schwarz S, Dosi PC, Schwarz KO, Brown EG, Strauss L
Pediatr Pathol 1986;6(2-3):259-65. doi: 10.3109/15513818609037717. PMID: 3822938

Prognosis

Stoecklin B, Choi YJ, Rakshasbhuvankar A, Svedenkrans J, Jones G, Pillow J
Thorax 2021 Jul;76(7):689-695. Epub 2021 Feb 11 doi: 10.1136/thoraxjnl-2020-214659. PMID: 33574124
MacLean JE, DeHaan K, Fuhr D, Hariharan S, Kamstra B, Hendson L, Adatia I, Majaesic C, Lovering AT, Thompson RB, Nicholas D, Thebaud B, Stickland MK
Thorax 2016 Nov;71(11):1012-1019. Epub 2016 Jun 3 doi: 10.1136/thoraxjnl-2015-207736. PMID: 27259338Free PMC Article
Hwang YS, Ma MC, Tseng YM, Tsai WH
Pediatr Neonatol 2013 Oct;54(5):309-14. Epub 2013 May 7 doi: 10.1016/j.pedneo.2013.03.013. PMID: 23660538
Streubel AH, Donohue PK, Aucott SW
J Perinatol 2008 Feb;28(2):141-8. Epub 2007 Dec 6 doi: 10.1038/sj.jp.7211894. PMID: 18059466
Hahn JS, Monyer H, Tharp BR
Electroencephalogr Clin Neurophysiol 1989 Nov;73(5):410-8. doi: 10.1016/0013-4694(89)90090-4. PMID: 2479519

Clinical prediction guides

Stoecklin B, Choi YJ, Rakshasbhuvankar A, Svedenkrans J, Jones G, Pillow J
Thorax 2021 Jul;76(7):689-695. Epub 2021 Feb 11 doi: 10.1136/thoraxjnl-2020-214659. PMID: 33574124
Bokiniec R, Własienko P, Borszewska-Kornacka M, Szymkiewicz-Dangel J
Echocardiography 2017 Apr;34(4):577-586. Epub 2017 Feb 23 doi: 10.1111/echo.13489. PMID: 28229480
MacLean JE, DeHaan K, Fuhr D, Hariharan S, Kamstra B, Hendson L, Adatia I, Majaesic C, Lovering AT, Thompson RB, Nicholas D, Thebaud B, Stickland MK
Thorax 2016 Nov;71(11):1012-1019. Epub 2016 Jun 3 doi: 10.1136/thoraxjnl-2015-207736. PMID: 27259338Free PMC Article
Chessex P, Bélanger S, Piedboeuf B, Pineault M
J Pediatr 1995 Apr;126(4):619-24. doi: 10.1016/s0022-3476(95)70364-0. PMID: 7699545
Shen-Schwarz S, Dosi PC, Schwarz KO, Brown EG, Strauss L
Pediatr Pathol 1986;6(2-3):259-65. doi: 10.3109/15513818609037717. PMID: 3822938

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