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Slowly Progressive Clinical Course

MedGen UID:
857160
•Concept ID:
C3897566
•
Finding

Definition

Clinical course characterized by slow progression without signs of aggressive disease. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSlowly Progressive Clinical Course

Professional guidelines

PubMed

Diagnosis and Treatment of Parkinson Disease: A Review.
Armstrong MJ, Okun MS
JAMA 2020 Feb 11;323(6):548-560. doi: 10.1001/jama.2019.22360. PMID: 32044947
Female Androgenetic Alopecia: An Update on Diagnosis and Management.
Starace M, Orlando G, Alessandrini A, Piraccini BM
Am J Clin Dermatol 2020 Feb;21(1):69-84. doi: 10.1007/s40257-019-00479-x. PMID: 31677111
Current Classification and Management of Inflammatory Myopathies.
Schmidt J
J Neuromuscul Dis 2018;5(2):109-129. doi: 10.3233/JND-180308. PMID: 29865091Free PMC Article

Recent clinical studies

Etiology

Distinct phenotypes in a cohort of anti-CASPR2 associated neurological syndromes.
Moura J, Samões R, Cardoso M, Sousa AP, Damásio J, Marinho A, Carneiro P, Neves E, Silva AM, Santos E
Clin Neurol Neurosurg 2023 Nov;234:107994. Epub 2023 Sep 30 doi: 10.1016/j.clineuro.2023.107994. PMID: 37797365
Prognostic value of the qSOFA in patients with acute exacerbation of idiopathic pulmonary fibrosis.
Yamazaki R, Nishiyama O, Yoshikawa K, Tohda Y, Matsumoto H
Respir Investig 2023 May;61(3):339-346. Epub 2023 Mar 17 doi: 10.1016/j.resinv.2023.02.006. PMID: 36933282
Cerebral neoplasm in L-2-hydroxyglutaric aciduria: two different presentations.
Dilber B, Havalı C, Eroglu N, Aydın K, Şahin S, Cansu A
Childs Nerv Syst 2020 Jul;36(7):1545-1548. Epub 2019 Dec 19 doi: 10.1007/s00381-019-04466-9. PMID: 31858216
Congenital myopathies: clinical phenotypes and new diagnostic tools.
Cassandrini D, Trovato R, Rubegni A, Lenzi S, Fiorillo C, Baldacci J, Minetti C, Astrea G, Bruno C, Santorelli FM; Italian Network on Congenital Myopathies
Ital J Pediatr 2017 Nov 15;43(1):101. doi: 10.1186/s13052-017-0419-z. PMID: 29141652Free PMC Article
Esophageal squamous papillomatosis.
Kao PC, Vecchio JA, Schned LM, Blaszyk H
Eur J Gastroenterol Hepatol 2005 Nov;17(11):1233-7. doi: 10.1097/00042737-200511000-00013. PMID: 16215437

Diagnosis

Distinct phenotypes in a cohort of anti-CASPR2 associated neurological syndromes.
Moura J, Samões R, Cardoso M, Sousa AP, Damásio J, Marinho A, Carneiro P, Neves E, Silva AM, Santos E
Clin Neurol Neurosurg 2023 Nov;234:107994. Epub 2023 Sep 30 doi: 10.1016/j.clineuro.2023.107994. PMID: 37797365
Congenital myopathies.
Younger DS
Handb Clin Neurol 2023;195:533-561. doi: 10.1016/B978-0-323-98818-6.00027-3. PMID: 37562885
Prognostic value of the qSOFA in patients with acute exacerbation of idiopathic pulmonary fibrosis.
Yamazaki R, Nishiyama O, Yoshikawa K, Tohda Y, Matsumoto H
Respir Investig 2023 May;61(3):339-346. Epub 2023 Mar 17 doi: 10.1016/j.resinv.2023.02.006. PMID: 36933282
Congenital myopathies: clinical phenotypes and new diagnostic tools.
Cassandrini D, Trovato R, Rubegni A, Lenzi S, Fiorillo C, Baldacci J, Minetti C, Astrea G, Bruno C, Santorelli FM; Italian Network on Congenital Myopathies
Ital J Pediatr 2017 Nov 15;43(1):101. doi: 10.1186/s13052-017-0419-z. PMID: 29141652Free PMC Article
Esophageal squamous papillomatosis.
Kao PC, Vecchio JA, Schned LM, Blaszyk H
Eur J Gastroenterol Hepatol 2005 Nov;17(11):1233-7. doi: 10.1097/00042737-200511000-00013. PMID: 16215437

Therapy

Postradiation lumbosacral radiculopathy with spinal root cavernomas mimicking carcinomatous meningitis.
Ducray F, Guillevin R, Psimaras D, Sanson M, Mokhtari K, Delanian S, Navarro S, Maisonobe T, Cornu P, Hoang-Xuan K, Delattre JY, Pradat PF
Neuro Oncol 2008 Dec;10(6):1035-9. Epub 2008 Aug 28 doi: 10.1215/15228517-2008-069. PMID: 18755918Free PMC Article
Cervical spine metastasis of multiple myeloma: a case report with 16 years of follow-up.
Wegener B, Müller PE, Jansson V, Krödel A, Heinert G, Dürr HR
Spine (Phila Pa 1976) 2004 Sep 1;29(17):E368-72. doi: 10.1097/01.brs.0000137298.64714.b0. PMID: 15534399
Slowly progressive ischemic stroke as first manifestation of essential thrombocythemia.
Benassi G, Ricci P, Calbucci F, Cacciatore FM, D'Alessandro R
Stroke 1989 Sep;20(9):1271-2. doi: 10.1161/01.str.20.9.1271. PMID: 2772987

Prognosis

Distinct phenotypes in a cohort of anti-CASPR2 associated neurological syndromes.
Moura J, Samões R, Cardoso M, Sousa AP, Damásio J, Marinho A, Carneiro P, Neves E, Silva AM, Santos E
Clin Neurol Neurosurg 2023 Nov;234:107994. Epub 2023 Sep 30 doi: 10.1016/j.clineuro.2023.107994. PMID: 37797365
Congenital myopathies.
Younger DS
Handb Clin Neurol 2023;195:533-561. doi: 10.1016/B978-0-323-98818-6.00027-3. PMID: 37562885
Alveolar soft part sarcoma: A case report and review of the literature.
Singh N, Gupta P, Misra S, Ahuja A, Jain VK
Cytopathology 2022 Sep;33(5):622-627. Epub 2022 May 26 doi: 10.1111/cyt.13134. PMID: 35488855
Congenital myopathies: clinical phenotypes and new diagnostic tools.
Cassandrini D, Trovato R, Rubegni A, Lenzi S, Fiorillo C, Baldacci J, Minetti C, Astrea G, Bruno C, Santorelli FM; Italian Network on Congenital Myopathies
Ital J Pediatr 2017 Nov 15;43(1):101. doi: 10.1186/s13052-017-0419-z. PMID: 29141652Free PMC Article
Esophageal squamous papillomatosis.
Kao PC, Vecchio JA, Schned LM, Blaszyk H
Eur J Gastroenterol Hepatol 2005 Nov;17(11):1233-7. doi: 10.1097/00042737-200511000-00013. PMID: 16215437

Clinical prediction guides

Evidence for spontaneous regulation of the humoral IgM anti-GM1 autoimmune response by IgG antibodies in multifocal motor neuropathy patients.
Di Egidio M, Bacaglio CR, Arrejoría R, Villa AM, Nores GA, Lopez PHH
J Peripher Nerv Syst 2023 Sep;28(3):398-406. Epub 2023 Aug 8 doi: 10.1111/jns.12583. PMID: 37498737
Prognostic value of the qSOFA in patients with acute exacerbation of idiopathic pulmonary fibrosis.
Yamazaki R, Nishiyama O, Yoshikawa K, Tohda Y, Matsumoto H
Respir Investig 2023 May;61(3):339-346. Epub 2023 Mar 17 doi: 10.1016/j.resinv.2023.02.006. PMID: 36933282
Postradiation lumbosacral radiculopathy with spinal root cavernomas mimicking carcinomatous meningitis.
Ducray F, Guillevin R, Psimaras D, Sanson M, Mokhtari K, Delanian S, Navarro S, Maisonobe T, Cornu P, Hoang-Xuan K, Delattre JY, Pradat PF
Neuro Oncol 2008 Dec;10(6):1035-9. Epub 2008 Aug 28 doi: 10.1215/15228517-2008-069. PMID: 18755918Free PMC Article
Clinical and histopathologic features of 8 patients with microscopic polyangiitis including two with a slowly progressive clinical course.
Kawakami T, Kawanabe T, Saito C, Kannari M, Mizoguchi M, Nagafuchi H, Okazaki T, Ozaki S, Kimura K, Soma Y
J Am Acad Dermatol 2007 Nov;57(5):840-8. doi: 10.1016/j.jaad.2007.05.012. PMID: 17939936
Strong association between IgA nephropathy and hepatitis B surface antigenemia in endemic areas.
Lai KN, Lai FM, Tam JS, Vallance-Owen J
Clin Nephrol 1988 May;29(5):229-34. PMID: 3293854

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