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Idiopathic Precocious Puberty

MedGen UID:
853627
Concept ID:
C2113596
Disease or Syndrome

Definition

Precocious puberty for which no underlying cause can be identified. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIdiopathic Precocious Puberty

Professional guidelines

PubMed

Vurallı D, Alikaşifoğlu A, İyigün İ, Canoruç D, Ozon A, Gönç N, Kandemir N
J Clin Res Pediatr Endocrinol 2020 Mar 19;12(1):37-44. Epub 2019 Jul 26 doi: 10.4274/jcrpe.galenos.2019.2019.0060. PMID: 31347350Free PMC Article
MacGillivray MH
N Engl J Med 1982 May 6;306(18):1109-10. doi: 10.1056/NEJM198205063061814. PMID: 7040953
Comite F, Cutler GB Jr, Rivier J, Vale WW, Loriaux DL, Crowley WF Jr
N Engl J Med 1981 Dec 24;305(26):1546-50. doi: 10.1056/NEJM198112243052602. PMID: 6458765

Recent clinical studies

Etiology

Loochi SA, Demol S, Nagelberg N, Lebenthal Y, Phillip M, Yackobovitch-Gavan M
J Pediatr Endocrinol Metab 2021 Mar 26;34(3):373-383. Epub 2021 Feb 22 doi: 10.1515/jpem-2020-0471. PMID: 33609438
Asci A, Durmaz E, Erkekoglu P, Pasli D, Bircan I, Kocer-Gumusel B
Minerva Pediatr 2014 Dec;66(6):571-8. PMID: 25336100
Yu CH, Liu PH, Van YH, Lien AS, Huang TP, Yen HR
Complement Ther Med 2014 Apr;22(2):258-65. Epub 2014 Jan 9 doi: 10.1016/j.ctim.2014.01.002. PMID: 24731897
Deng F, Tao FB, Liu DY, Xu YY, Hao JH, Sun Y, Su PY
Eur J Endocrinol 2012 May;166(5):803-9. Epub 2012 Feb 8 doi: 10.1530/EJE-11-0876. PMID: 22318748
Roberts MW, Li SH, Comite F, Hench KD, Pescovitz OH, Cutler GB Jr, Loriaux DL
J Dent Res 1985 Aug;64(8):1084-6. doi: 10.1177/00220345850640081301. PMID: 3860542

Diagnosis

Yu CH, Liu PH, Van YH, Lien AS, Huang TP, Yen HR
Complement Ther Med 2014 Apr;22(2):258-65. Epub 2014 Jan 9 doi: 10.1016/j.ctim.2014.01.002. PMID: 24731897
Deng F, Tao FB, Liu DY, Xu YY, Hao JH, Sun Y, Su PY
Eur J Endocrinol 2012 May;166(5):803-9. Epub 2012 Feb 8 doi: 10.1530/EJE-11-0876. PMID: 22318748
Papadimitriou A, Beri D, Tsialla A, Fretzayas A, Psychou F, Nicolaidou P
J Pediatr 2006 Jul;149(1):43-6. doi: 10.1016/j.jpeds.2006.02.005. PMID: 16860125
Tatò L, Savage MO, Antoniazzi F, Buzi F, Di Maio S, Oostdijk W, Pasquino AM, Raiola G, Saenger P, Tonini G, Voorhoeve PG; International Workshop on Management of Puberty for Optimum Auxological Results
J Pediatr Endocrinol Metab 2001 Jul;14 Suppl 2:985-95. doi: 10.1515/jpem-2001-s211. PMID: 11529405
Styne DM
Endocrinol Metab Clin North Am 1991 Mar;20(1):43-69. PMID: 2029888

Therapy

Loochi SA, Demol S, Nagelberg N, Lebenthal Y, Phillip M, Yackobovitch-Gavan M
J Pediatr Endocrinol Metab 2021 Mar 26;34(3):373-383. Epub 2021 Feb 22 doi: 10.1515/jpem-2020-0471. PMID: 33609438
Asci A, Durmaz E, Erkekoglu P, Pasli D, Bircan I, Kocer-Gumusel B
Minerva Pediatr 2014 Dec;66(6):571-8. PMID: 25336100
Yu CH, Liu PH, Van YH, Lien AS, Huang TP, Yen HR
Complement Ther Med 2014 Apr;22(2):258-65. Epub 2014 Jan 9 doi: 10.1016/j.ctim.2014.01.002. PMID: 24731897
Tatò L, Savage MO, Antoniazzi F, Buzi F, Di Maio S, Oostdijk W, Pasquino AM, Raiola G, Saenger P, Tonini G, Voorhoeve PG; International Workshop on Management of Puberty for Optimum Auxological Results
J Pediatr Endocrinol Metab 2001 Jul;14 Suppl 2:985-95. doi: 10.1515/jpem-2001-s211. PMID: 11529405
Swerdloff RS, Heber D
Annu Rev Med 1983;34:491-500. doi: 10.1146/annurev.me.34.020183.002423. PMID: 6344774

Prognosis

Yu CH, Liu PH, Van YH, Lien AS, Huang TP, Yen HR
Complement Ther Med 2014 Apr;22(2):258-65. Epub 2014 Jan 9 doi: 10.1016/j.ctim.2014.01.002. PMID: 24731897
Lazar L, Meyerovitch J, de Vries L, Phillip M, Lebenthal Y
Clin Endocrinol (Oxf) 2014 Apr;80(4):570-6. Epub 2013 Sep 18 doi: 10.1111/cen.12319. PMID: 24033561
Papadimitriou A, Nicolaidou P, Fretzayas A, Chrousos GP
J Clin Endocrinol Metab 2010 Oct;95(10):4535-41. Epub 2010 Jul 7 doi: 10.1210/jc.2010-0895. PMID: 20610589
Léger J, Reynaud R, Czernichow P
J Pediatr 2000 Dec;137(6):819-25. doi: 10.1067/mpd.2000.109201. PMID: 11113839
Imai A, Horibe S, Tamaya T
Int J Gynaecol Obstet 1995 Apr;49(1):41-5. doi: 10.1016/0020-7292(94)02305-i. PMID: 9457983

Clinical prediction guides

Loochi SA, Demol S, Nagelberg N, Lebenthal Y, Phillip M, Yackobovitch-Gavan M
J Pediatr Endocrinol Metab 2021 Mar 26;34(3):373-383. Epub 2021 Feb 22 doi: 10.1515/jpem-2020-0471. PMID: 33609438
Vurallı D, Alikaşifoğlu A, İyigün İ, Canoruç D, Ozon A, Gönç N, Kandemir N
J Clin Res Pediatr Endocrinol 2020 Mar 19;12(1):37-44. Epub 2019 Jul 26 doi: 10.4274/jcrpe.galenos.2019.2019.0060. PMID: 31347350Free PMC Article
Asci A, Durmaz E, Erkekoglu P, Pasli D, Bircan I, Kocer-Gumusel B
Minerva Pediatr 2014 Dec;66(6):571-8. PMID: 25336100
Yu CH, Liu PH, Van YH, Lien AS, Huang TP, Yen HR
Complement Ther Med 2014 Apr;22(2):258-65. Epub 2014 Jan 9 doi: 10.1016/j.ctim.2014.01.002. PMID: 24731897
Papadimitriou A, Nicolaidou P, Fretzayas A, Chrousos GP
J Clin Endocrinol Metab 2010 Oct;95(10):4535-41. Epub 2010 Jul 7 doi: 10.1210/jc.2010-0895. PMID: 20610589

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