U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pneumonia caused by methicillin resistant Staphylococcus aureus

MedGen UID:
853161
•Concept ID:
C1142536
•
Disease or Syndrome
Synonyms: Methicillin-Resistant Staphylococcus aureus Pneumonia; MRSA Pneumonia
SNOMED CT: Pneumonia caused by methicillin resistant Staphylococcus aureus (124691000119101)

Definition

Pneumonia that is caused by Staphylococcus aureus that is resistant to methicillin treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPneumonia caused by methicillin resistant Staphylococcus aureus

Professional guidelines

PubMed

Pharmacodynamics, pharmacokinetics and clinical efficacy of telavancin in the treatment of pneumonia.
Adamantia L, Antoni T
Expert Opin Drug Metab Toxicol 2016 Jul;12(7):803-12. Epub 2016 May 30 doi: 10.1080/17425255.2016.1187599. PMID: 27158752
Current review of antimicrobial treatment of nosocomial pneumonia caused by multidrug-resistant pathogens.
Jean SS, Hsueh PR
Expert Opin Pharmacother 2011 Oct;12(14):2145-8. doi: 10.1517/14656566.2011.599320. PMID: 21895553
Treatment of hospital-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus.
Ferrara AM
Int J Antimicrob Agents 2007 Jul;30(1):19-24. Epub 2007 May 1 doi: 10.1016/j.ijantimicag.2007.02.011. PMID: 17475449

Recent clinical studies

Etiology

Priorities and Progress in Gram-positive Bacterial Infection Research by the Antibacterial Resistance Leadership Group: A Narrative Review.
Doernberg SB, Arias CA, Altman DR, Babiker A, Boucher HW, Creech CB, Cosgrove SE, Evans SR, Fowler VG, Fritz SA, Hamasaki T, Kelly BJ, Leal SM, Liu C, Lodise TP, Miller LG, Munita JM, Murray BE, Pettigrew MM, Ruffin F, Scheetz MH, Shopsin B, Tran TT, Turner NA, Williams DJ, Zaharoff S, Holland TL; Antibacterial Resistance Leadership Group
Clin Infect Dis 2023 Oct 16;77(Suppl 4):S295-S304. doi: 10.1093/cid/ciad565. PMID: 37843115Free PMC Article
Bacterial co-infections with SARS-CoV-2.
Mirzaei R, Goodarzi P, Asadi M, Soltani A, Aljanabi HAA, Jeda AS, Dashtbin S, Jalalifar S, Mohammadzadeh R, Teimoori A, Tari K, Salari M, Ghiasvand S, Kazemi S, Yousefimashouf R, Keyvani H, Karampoor S
IUBMB Life 2020 Oct;72(10):2097-2111. Epub 2020 Aug 8 doi: 10.1002/iub.2356. PMID: 32770825Free PMC Article
Staphylococcus aureus Pneumonia in the Community.
He H, Wunderink RG
Semin Respir Crit Care Med 2020 Aug;41(4):470-479. Epub 2020 Jun 10 doi: 10.1055/s-0040-1709992. PMID: 32521547
Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent.
Zhanel GG, Esquivel J, Zelenitsky S, Lawrence CK, Adam HJ, Golden A, Hink R, Berry L, Schweizer F, Zhanel MA, Bay D, Lagacé-Wiens PRS, Walkty AJ, Lynch JP 3rd, Karlowsky JA
Drugs 2020 Feb;80(3):285-313. doi: 10.1007/s40265-020-01257-4. PMID: 31970713
The Clinical Utility of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening to Rule Out MRSA Pneumonia: A Diagnostic Meta-analysis With Antimicrobial Stewardship Implications.
Parente DM, Cunha CB, Mylonakis E, Timbrook TT
Clin Infect Dis 2018 Jun 18;67(1):1-7. doi: 10.1093/cid/ciy024. PMID: 29340593

Diagnosis

Infectious Pulmonary Diseases.
Rafeq R, Igneri LA
Infect Dis Clin North Am 2024 Mar;38(1):1-17. doi: 10.1016/j.idc.2023.12.006. PMID: 38280758
Systematic review of ceftaroline fosamil in the management of patients with methicillin-resistant Staphylococcus aureus pneumonia.
Torres A, Kuraieva A, Stone GG, Cillóniz C
Eur Respir Rev 2023 Dec 31;32(170) Epub 2023 Oct 18 doi: 10.1183/16000617.0117-2023. PMID: 37852658Free PMC Article
Prevalence and Therapies of Antibiotic-Resistance in Staphylococcus aureus.
Guo Y, Song G, Sun M, Wang J, Wang Y
Front Cell Infect Microbiol 2020;10:107. Epub 2020 Mar 17 doi: 10.3389/fcimb.2020.00107. PMID: 32257966Free PMC Article
Linezolid: a review of its properties, function, and use in critical care.
Hashemian SMR, Farhadi T, Ganjparvar M
Drug Des Devel Ther 2018;12:1759-1767. Epub 2018 Jun 18 doi: 10.2147/DDDT.S164515. PMID: 29950810Free PMC Article
The Clinical Utility of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening to Rule Out MRSA Pneumonia: A Diagnostic Meta-analysis With Antimicrobial Stewardship Implications.
Parente DM, Cunha CB, Mylonakis E, Timbrook TT
Clin Infect Dis 2018 Jun 18;67(1):1-7. doi: 10.1093/cid/ciy024. PMID: 29340593

Therapy

Systematic review of ceftaroline fosamil in the management of patients with methicillin-resistant Staphylococcus aureus pneumonia.
Torres A, Kuraieva A, Stone GG, Cillóniz C
Eur Respir Rev 2023 Dec 31;32(170) Epub 2023 Oct 18 doi: 10.1183/16000617.0117-2023. PMID: 37852658Free PMC Article
Bacterial co-infections with SARS-CoV-2.
Mirzaei R, Goodarzi P, Asadi M, Soltani A, Aljanabi HAA, Jeda AS, Dashtbin S, Jalalifar S, Mohammadzadeh R, Teimoori A, Tari K, Salari M, Ghiasvand S, Kazemi S, Yousefimashouf R, Keyvani H, Karampoor S
IUBMB Life 2020 Oct;72(10):2097-2111. Epub 2020 Aug 8 doi: 10.1002/iub.2356. PMID: 32770825Free PMC Article
Staphylococcus aureus Pneumonia in the Community.
He H, Wunderink RG
Semin Respir Crit Care Med 2020 Aug;41(4):470-479. Epub 2020 Jun 10 doi: 10.1055/s-0040-1709992. PMID: 32521547
Prevalence and Therapies of Antibiotic-Resistance in Staphylococcus aureus.
Guo Y, Song G, Sun M, Wang J, Wang Y
Front Cell Infect Microbiol 2020;10:107. Epub 2020 Mar 17 doi: 10.3389/fcimb.2020.00107. PMID: 32257966Free PMC Article
Linezolid: a review of its properties, function, and use in critical care.
Hashemian SMR, Farhadi T, Ganjparvar M
Drug Des Devel Ther 2018;12:1759-1767. Epub 2018 Jun 18 doi: 10.2147/DDDT.S164515. PMID: 29950810Free PMC Article

Prognosis

Priorities and Progress in Gram-positive Bacterial Infection Research by the Antibacterial Resistance Leadership Group: A Narrative Review.
Doernberg SB, Arias CA, Altman DR, Babiker A, Boucher HW, Creech CB, Cosgrove SE, Evans SR, Fowler VG, Fritz SA, Hamasaki T, Kelly BJ, Leal SM, Liu C, Lodise TP, Miller LG, Munita JM, Murray BE, Pettigrew MM, Ruffin F, Scheetz MH, Shopsin B, Tran TT, Turner NA, Williams DJ, Zaharoff S, Holland TL; Antibacterial Resistance Leadership Group
Clin Infect Dis 2023 Oct 16;77(Suppl 4):S295-S304. doi: 10.1093/cid/ciad565. PMID: 37843115Free PMC Article
Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent.
Zhanel GG, Esquivel J, Zelenitsky S, Lawrence CK, Adam HJ, Golden A, Hink R, Berry L, Schweizer F, Zhanel MA, Bay D, Lagacé-Wiens PRS, Walkty AJ, Lynch JP 3rd, Karlowsky JA
Drugs 2020 Feb;80(3):285-313. doi: 10.1007/s40265-020-01257-4. PMID: 31970713
Therapeutic Drug Monitoring Can Improve Linezolid Dosing Regimens in Current Clinical Practice: A Review of Linezolid Pharmacokinetics and Pharmacodynamics.
Rao GG, Konicki R, Cattaneo D, Alffenaar JW, Marriott DJE, Neely M; IATDMCT Antimicrobial Scientific Committee
Ther Drug Monit 2020 Feb;42(1):83-92. doi: 10.1097/FTD.0000000000000710. PMID: 31652190
The Clinical Utility of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening to Rule Out MRSA Pneumonia: A Diagnostic Meta-analysis With Antimicrobial Stewardship Implications.
Parente DM, Cunha CB, Mylonakis E, Timbrook TT
Clin Infect Dis 2018 Jun 18;67(1):1-7. doi: 10.1093/cid/ciy024. PMID: 29340593
Cefditoren pivoxil.
Darkes MJ, Plosker GL
Drugs 2002;62(2):319-36; discussion 337-8. doi: 10.2165/00003495-200262020-00006. PMID: 11817976

Clinical prediction guides

Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent.
Zhanel GG, Esquivel J, Zelenitsky S, Lawrence CK, Adam HJ, Golden A, Hink R, Berry L, Schweizer F, Zhanel MA, Bay D, Lagacé-Wiens PRS, Walkty AJ, Lynch JP 3rd, Karlowsky JA
Drugs 2020 Feb;80(3):285-313. doi: 10.1007/s40265-020-01257-4. PMID: 31970713
Therapeutic Drug Monitoring Can Improve Linezolid Dosing Regimens in Current Clinical Practice: A Review of Linezolid Pharmacokinetics and Pharmacodynamics.
Rao GG, Konicki R, Cattaneo D, Alffenaar JW, Marriott DJE, Neely M; IATDMCT Antimicrobial Scientific Committee
Ther Drug Monit 2020 Feb;42(1):83-92. doi: 10.1097/FTD.0000000000000710. PMID: 31652190
The Clinical Utility of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Screening to Rule Out MRSA Pneumonia: A Diagnostic Meta-analysis With Antimicrobial Stewardship Implications.
Parente DM, Cunha CB, Mylonakis E, Timbrook TT
Clin Infect Dis 2018 Jun 18;67(1):1-7. doi: 10.1093/cid/ciy024. PMID: 29340593
The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis.
Klein EY, Monteforte B, Gupta A, Jiang W, May L, Hsieh YH, Dugas A
Influenza Other Respir Viruses 2016 Sep;10(5):394-403. Epub 2016 Jun 24 doi: 10.1111/irv.12398. PMID: 27232677Free PMC Article
Iclaprim.
Kohlhoff SA, Sharma R
Expert Opin Investig Drugs 2007 Sep;16(9):1441-8. doi: 10.1517/13543784.16.9.1441. PMID: 17714029

Recent systematic reviews

Systematic review of ceftaroline fosamil in the management of patients with methicillin-resistant Staphylococcus aureus pneumonia.
Torres A, Kuraieva A, Stone GG, Cillóniz C
Eur Respir Rev 2023 Dec 31;32(170) Epub 2023 Oct 18 doi: 10.1183/16000617.0117-2023. PMID: 37852658Free PMC Article
Community-genotype methicillin-resistant Staphylococcus aureus skin and soft tissue infections in Latin America: a systematic review.
Leme RCP, Bispo PJM, Salles MJ
Braz J Infect Dis 2021 Jan-Feb;25(1):101539. Epub 2021 Feb 16 doi: 10.1016/j.bjid.2021.101539. PMID: 33607082Free PMC Article
Therapeutic Drug Monitoring Can Improve Linezolid Dosing Regimens in Current Clinical Practice: A Review of Linezolid Pharmacokinetics and Pharmacodynamics.
Rao GG, Konicki R, Cattaneo D, Alffenaar JW, Marriott DJE, Neely M; IATDMCT Antimicrobial Scientific Committee
Ther Drug Monit 2020 Feb;42(1):83-92. doi: 10.1097/FTD.0000000000000710. PMID: 31652190
Community-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus in critically-ill patients: systematic review.
Carballo N, De Antonio-Cuscó M, Echeverría-Esnal D, Luque S, Salas E, Grau S
Farm Hosp 2017 Mar 1;41(2):187-203. doi: 10.7399/fh.2017.41.2.10591. PMID: 28236797
The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis.
Klein EY, Monteforte B, Gupta A, Jiang W, May L, Hsieh YH, Dugas A
Influenza Other Respir Viruses 2016 Sep;10(5):394-403. Epub 2016 Jun 24 doi: 10.1111/irv.12398. PMID: 27232677Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...