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Skin sensation disturbance

MedGen UID:
8444
•Concept ID:
C0012766
•
Sign or Symptom
Synonyms: Disturbance of Skin Sensation; Skin Sensation Disturbance
SNOMED CT: Skin sensation disturbance (80910005)

Definition

Disruption of the normal functioning of the sensory nerves in the skin. [from NCI]

Professional guidelines

PubMed

Disease burden and treatment satisfaction in patients with prurigo nodularis in Japan.
Murota H, Arima K, Yoshida T, Fujita H
J Dermatol 2024 Feb;51(2):223-233. Epub 2023 Dec 8 doi: 10.1111/1346-8138.17045. PMID: 38066728Free PMC Article
Management of vulvar pain.
Fischer G
Dermatol Ther 2004;17(1):134-49. doi: 10.1111/j.1396-0296.2004.04014.x. PMID: 14756898
The role of rehabilitation in the treatment of balance disorders.
Abatzides GJ, Kitsios A
J Back Musculoskelet Rehabil 1999;12(2):101-12. doi: 10.3233/bmr-1999-12203. PMID: 11758567

Recent clinical studies

Etiology

Disturbance of skin sensation and autism spectrum disorder: A bidirectional Mendelian randomization study.
Zhong X, Wang L, Xu L, Lian J, Chen J, Gong X, Shao Y
Brain Behav 2023 Nov;13(11):e3238. Epub 2023 Sep 5 doi: 10.1002/brb3.3238. PMID: 37670485Free PMC Article
Itch: Epidemiology, clinical presentation, and diagnostic workup.
Roh YS, Choi J, Sutaria N, Kwatra SG
J Am Acad Dermatol 2022 Jan;86(1):1-14. Epub 2021 Aug 21 doi: 10.1016/j.jaad.2021.07.076. PMID: 34428534Free PMC Article
A Synoptic Overview of Neurovascular Interactions in the Foot.
Balasubramanian G, Vas P, Chockalingam N, Naemi R
Front Endocrinol (Lausanne) 2020;11:308. Epub 2020 May 22 doi: 10.3389/fendo.2020.00308. PMID: 32528410Free PMC Article
The proprioceptive senses: their roles in signaling body shape, body position and movement, and muscle force.
Proske U, Gandevia SC
Physiol Rev 2012 Oct;92(4):1651-97. doi: 10.1152/physrev.00048.2011. PMID: 23073629
Shoulder-hand syndrome after stroke. A complex regional pain syndrome.
Pertoldi S, Di Benedetto P
Eura Medicophys 2005 Dec;41(4):283-92. PMID: 16474282

Diagnosis

Patient Perspectives on Living With Severe Prurigo Nodularis.
Rodriguez D, Kwatra SG, Dias-Barbosa C, Zeng F, Jabbar Lopez ZK, Piketty C, Puelles J
JAMA Dermatol 2023 Nov 1;159(11):1205-1212. doi: 10.1001/jamadermatol.2023.3251. PMID: 37728897Free PMC Article
Small fiber neuropathy.
Finsterer J, Scorza FA
Acta Neurol Scand 2022 May;145(5):493-503. Epub 2022 Feb 7 doi: 10.1111/ane.13591. PMID: 35130356
Itch: Epidemiology, clinical presentation, and diagnostic workup.
Roh YS, Choi J, Sutaria N, Kwatra SG
J Am Acad Dermatol 2022 Jan;86(1):1-14. Epub 2021 Aug 21 doi: 10.1016/j.jaad.2021.07.076. PMID: 34428534Free PMC Article
Sensitive skin.
Misery L, Loser K, Ständer S
J Eur Acad Dermatol Venereol 2016 Feb;30 Suppl 1:2-8. doi: 10.1111/jdv.13532. PMID: 26805416
Shoulder-hand syndrome after stroke. A complex regional pain syndrome.
Pertoldi S, Di Benedetto P
Eura Medicophys 2005 Dec;41(4):283-92. PMID: 16474282

Therapy

Disturbance of skin sensation and autism spectrum disorder: A bidirectional Mendelian randomization study.
Zhong X, Wang L, Xu L, Lian J, Chen J, Gong X, Shao Y
Brain Behav 2023 Nov;13(11):e3238. Epub 2023 Sep 5 doi: 10.1002/brb3.3238. PMID: 37670485Free PMC Article
Ruxolitinib Cream 1.5%: A Review in Mild to Moderate Atopic Dermatitis.
Hoy SM
Am J Clin Dermatol 2023 Jan;24(1):143-151. Epub 2022 Dec 20 doi: 10.1007/s40257-022-00748-2. PMID: 36538235Free PMC Article
Small fiber neuropathy.
Finsterer J, Scorza FA
Acta Neurol Scand 2022 May;145(5):493-503. Epub 2022 Feb 7 doi: 10.1111/ane.13591. PMID: 35130356
Hypnotherapy for complex regional pain syndrome.
Thomson L
Am J Clin Hypn 2022 Jan;64(3):195-205. doi: 10.1080/00029157.2021.1943298. PMID: 35007485
Zinc and Taste Disturbances in Older Adults: A Review of the Literature.
Pisano M, Hilas O
Consult Pharm 2016 May;31(5):267-70. doi: 10.4140/TCP.n.2016.267. PMID: 27178656

Prognosis

The pathogenesis of painful diabetic neuropathy and clinical presentation.
Staehelin Jensen T
Diabetes Res Clin Pract 2023 Dec;206 Suppl 1:110753. doi: 10.1016/j.diabres.2023.110753. PMID: 38245319
A Synoptic Overview of Neurovascular Interactions in the Foot.
Balasubramanian G, Vas P, Chockalingam N, Naemi R
Front Endocrinol (Lausanne) 2020;11:308. Epub 2020 May 22 doi: 10.3389/fendo.2020.00308. PMID: 32528410Free PMC Article
Skin diseases associated with Agent Orange and other organochlorine exposures.
Patterson AT, Kaffenberger BH, Keller RA, Elston DM
J Am Acad Dermatol 2016 Jan;74(1):143-70. Epub 2015 Jul 22 doi: 10.1016/j.jaad.2015.05.006. PMID: 26210237
Cardiovascular and urological dysfunction in spinal cord injury.
Hagen EM, Faerestrand S, Hoff JM, Rekand T, Gronning M
Acta Neurol Scand Suppl 2011;(191):71-8. doi: 10.1111/j.1600-0404.2011.01547.x. PMID: 21711260
Hereditary sensory neuropathy type I.
Auer-Grumbach M
Orphanet J Rare Dis 2008 Mar 18;3:7. doi: 10.1186/1750-1172-3-7. PMID: 18348718Free PMC Article

Clinical prediction guides

Non-Skin Related Symptoms Are Common in Chronic Spontaneous Urticaria and Linked to Active and Uncontrolled Disease: Results From the Chronic Urticaria Registry.
Pyatilova P, Hackler Y, Aulenbacher F, Asero R, Bauer A, Bizjak M, Day C, Dissemond J, Du-Thanh A, Fomina D, Giménez-Arnau AM, Grattan C, Gregoriou S, Hawro T, Kasperska-Zajac A, Khoshkhui M, Kocatürk E, Kovalkova E, Kulthanan K, Kuznetsova E, Makris M, Mukhina O, Pesqué D, Peter J, Salameh P, Siebenhaar F, Sikora A, Staubach P, Tuchinda P, Zamłyński M, Weller K, Maurer M, Kolkhir P
J Allergy Clin Immunol Pract 2024 Jul;12(7):1890-1899.e3. Epub 2024 Apr 24 doi: 10.1016/j.jaip.2024.04.027. PMID: 38670260
Disease burden and treatment satisfaction in patients with prurigo nodularis in Japan.
Murota H, Arima K, Yoshida T, Fujita H
J Dermatol 2024 Feb;51(2):223-233. Epub 2023 Dec 8 doi: 10.1111/1346-8138.17045. PMID: 38066728Free PMC Article
Fibromyalgia syndrome and the eye-A review.
Zdebik N, Zdebik A, Bogusławska J, Przeździecka-Dołyk J, Turno-Kręcicka A
Surv Ophthalmol 2021 Jan-Feb;66(1):132-137. Epub 2020 Jun 5 doi: 10.1016/j.survophthal.2020.05.006. PMID: 32512032
A Synoptic Overview of Neurovascular Interactions in the Foot.
Balasubramanian G, Vas P, Chockalingam N, Naemi R
Front Endocrinol (Lausanne) 2020;11:308. Epub 2020 May 22 doi: 10.3389/fendo.2020.00308. PMID: 32528410Free PMC Article
Hereditary sensory neuropathy type I.
Auer-Grumbach M
Orphanet J Rare Dis 2008 Mar 18;3:7. doi: 10.1186/1750-1172-3-7. PMID: 18348718Free PMC Article

Recent systematic reviews

Interventions for chronic pruritus of unknown origin.
Andrade A, Kuah CY, Martin-Lopez JE, Chua S, Shpadaruk V, Sanclemente G, Franco JV
Cochrane Database Syst Rev 2020 Jan 25;1(1):CD013128. doi: 10.1002/14651858.CD013128.pub2. PMID: 31981369Free PMC Article
Skin diseases associated with Agent Orange and other organochlorine exposures.
Patterson AT, Kaffenberger BH, Keller RA, Elston DM
J Am Acad Dermatol 2016 Jan;74(1):143-70. Epub 2015 Jul 22 doi: 10.1016/j.jaad.2015.05.006. PMID: 26210237

Supplemental Content

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