U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cutaneous polyarteritis nodosa

MedGen UID:
83358
Concept ID:
C0343190
Disease or Syndrome
Synonyms: Cutaneous livedo with nodules; Cutaneous PAN; cutaneous PAN; Cutaneous periarteritis nodosa; cutaneous periarteritis nodosa; Cutaneous Polyarteritis Nodosa; cutaneous polyarteritis nodosa; Nodular livedo
SNOMED CT: Cutaneous polyarteritis nodosa (239926000); Cutaneous livedo with nodules (239926000); Nodular livedo (239926000)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0018592
Orphanet: ORPHA439729

Definition

Cutaneous polyarteritis nodosa (CPAN) is a rare limited form of polyarteritis nodosa (PAN, see this term), characterized by cutaneous vasculitis and mild and transient extracutaneous manifestations such as mild arthralgia, arthritis,myalgia, and rarely peripheral neuropathy. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCutaneous polyarteritis nodosa

Professional guidelines

PubMed

Elston DM
J Am Acad Dermatol 2022 Dec;87(6):1273-1274. Epub 2022 May 26 doi: 10.1016/j.jaad.2022.05.043. PMID: 35643240
Micheletti RG, Pagnoux C
Presse Med 2020 Oct;49(3):104033. Epub 2020 Jul 6 doi: 10.1016/j.lpm.2020.104033. PMID: 32645416
Ting TV
Pediatr Clin North Am 2014 Apr;61(2):321-46. Epub 2014 Jan 21 doi: 10.1016/j.pcl.2013.11.007. PMID: 24636649

Recent clinical studies

Etiology

Stewart M, Lo A, Shojania K, Au S, Seidman MA, Dutz JP, Chan J
J Am Acad Dermatol 2022 Dec;87(6):1370-1373. Epub 2022 Jun 14 doi: 10.1016/j.jaad.2022.06.009. PMID: 35714785
Morita TCAB, Trés GFS, García MSC, Halpern I, Criado PR, de Carvalho JF
Adv Rheumatol 2019 Aug 1;59(1):35. doi: 10.1186/s42358-019-0077-5. PMID: 31370889
Caproni M, Verdelli A
Curr Opin Rheumatol 2019 Jan;31(1):46-52. doi: 10.1097/BOR.0000000000000563. PMID: 30394939
Collins MP, Hadden RD
Nat Rev Neurol 2017 Apr 27;13(5):302-316. doi: 10.1038/nrneurol.2017.42. PMID: 28447661
Sharma A, Dogra S, Sharma K
Dermatol Clin 2015 Jul;33(3):475-87. doi: 10.1016/j.det.2015.03.012. PMID: 26143427

Diagnosis

Micheletti RG, Pagnoux C
Presse Med 2020 Oct;49(3):104033. Epub 2020 Jul 6 doi: 10.1016/j.lpm.2020.104033. PMID: 32645416
Collins MP, Hadden RD
Nat Rev Neurol 2017 Apr 27;13(5):302-316. doi: 10.1038/nrneurol.2017.42. PMID: 28447661
Sharma A, Dogra S, Sharma K
Dermatol Clin 2015 Jul;33(3):475-87. doi: 10.1016/j.det.2015.03.012. PMID: 26143427
Díaz-Pérez JL, De Lagrán ZM, Díaz-Ramón JL, Winkelmann RK
Semin Cutan Med Surg 2007 Jun;26(2):77-86. doi: 10.1016/j.sder.2007.02.003. PMID: 17544958
Luis Rodríguez-Peralto J, Carrillo R, Rosales B, Rodríguez-Gil Y
Semin Cutan Med Surg 2007 Jun;26(2):71-6. doi: 10.1016/j.sder.2007.02.002. PMID: 17544957

Therapy

Bettuzzi T, Jachiet M, Sbidian E, Frumholtz L, Cordoliani F, Mouthon L, Chasset F, Paule R, Bouaziz JD, Guillevin L, Terrier B, Aractingi S, Dupin N, Régent A
J Am Acad Dermatol 2022 May;86(5):1035-1041. Epub 2021 Jul 2 doi: 10.1016/j.jaad.2021.06.872. PMID: 34224771
Micheletti RG, Pagnoux C
Presse Med 2020 Oct;49(3):104033. Epub 2020 Jul 6 doi: 10.1016/j.lpm.2020.104033. PMID: 32645416
Morita TCAB, Trés GFS, García MSC, Halpern I, Criado PR, de Carvalho JF
Adv Rheumatol 2019 Aug 1;59(1):35. doi: 10.1186/s42358-019-0077-5. PMID: 31370889
Sharma A, Dogra S, Sharma K
Dermatol Clin 2015 Jul;33(3):475-87. doi: 10.1016/j.det.2015.03.012. PMID: 26143427
Moreland LW, Ball GV
Am J Med 1990 Apr;88(4):426-30. doi: 10.1016/0002-9343(90)90502-5. PMID: 1970223

Prognosis

Bettuzzi T, Jachiet M, Sbidian E, Frumholtz L, Cordoliani F, Mouthon L, Chasset F, Paule R, Bouaziz JD, Guillevin L, Terrier B, Aractingi S, Dupin N, Régent A
J Am Acad Dermatol 2022 May;86(5):1035-1041. Epub 2021 Jul 2 doi: 10.1016/j.jaad.2021.06.872. PMID: 34224771
Kolivras A, Thompson C
Clin Dermatol 2021 Mar-Apr;39(2):278-282. Epub 2020 Oct 16 doi: 10.1016/j.clindermatol.2020.10.011. PMID: 34272022
Díaz-Pérez JL, De Lagrán ZM, Díaz-Ramón JL, Winkelmann RK
Semin Cutan Med Surg 2007 Jun;26(2):77-86. doi: 10.1016/j.sder.2007.02.003. PMID: 17544958
Bauzá A, España A, Idoate M
Br J Dermatol 2002 Apr;146(4):694-9. doi: 10.1046/j.1365-2133.2002.04624.x. PMID: 11966708
Sheth AP, Olson JC, Esterly NB
J Am Acad Dermatol 1994 Oct;31(4):561-6. doi: 10.1016/s0190-9622(94)70216-0. PMID: 7916355

Clinical prediction guides

Bettuzzi T, Jachiet M, Sbidian E, Frumholtz L, Cordoliani F, Mouthon L, Chasset F, Paule R, Bouaziz JD, Guillevin L, Terrier B, Aractingi S, Dupin N, Régent A
J Am Acad Dermatol 2022 May;86(5):1035-1041. Epub 2021 Jul 2 doi: 10.1016/j.jaad.2021.06.872. PMID: 34224771
Munera-Campos M, Bielsa I, Martínez-Morillo M, Aparicio G, Olivé A, Ferrándiz C
J Dtsch Dermatol Ges 2020 Nov;18(11):1250-1259. Epub 2020 Oct 4 doi: 10.1111/ddg.14271. PMID: 33015940
He Q, Shu J, Chen F, Zhen XF
Curr Neurovasc Res 2019;16(3):208-214. doi: 10.2174/1567202616666190618112705. PMID: 31237213
Kato A, Hamada T, Miyake T, Morizane S, Hirai Y, Yamasaki O, Iwatsuki K
JAMA Dermatol 2018 Aug 1;154(8):922-926. doi: 10.1001/jamadermatol.2018.1601. PMID: 29955757Free PMC Article
Chasset F, Francès C
Clin Rev Allergy Immunol 2017 Dec;53(3):452-468. doi: 10.1007/s12016-017-8612-9. PMID: 28547523

Recent systematic reviews

Papachristodoulou E, Kakoullis L, Tiniakou E, Parperis K
Rheumatology (Oxford) 2021 Sep 1;60(9):4039-4047. doi: 10.1093/rheumatology/keab402. PMID: 33944902
Diaconescu S, Strat S, Balan GG, Anton C, Stefanescu G, Ioniuc I, Stanescu AMA
Medicina (Kaunas) 2020 Aug 23;56(9) doi: 10.3390/medicina56090425. PMID: 32842528Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...