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Pituitary hemorrhage

MedGen UID:
83340
•Concept ID:
C0342406
•
Pathologic Function
Synonym: Pituitary Hemorrhage
SNOMED CT: Pituitary hemorrhage (237702003)

Definition

Bleeding within the pituitary gland. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPituitary hemorrhage

Professional guidelines

PubMed

Frequency of pituitary tumor apoplexy during treatment of prolactinomas with dopamine agonists: a systematic review.
Carija R, Vucina D
CNS Neurol Disord Drug Targets 2012 Dec;11(8):1012-4. doi: 10.2174/1871527311211080011. PMID: 23244423
Clinical versus subclinical pituitary apoplexy: presentation, surgical management, and outcome in 21 patients.
Onesti ST, Wisniewski T, Post KD
Neurosurgery 1990 Jun;26(6):980-6. PMID: 2362675

Recent clinical studies

Etiology

Pituitary tumor apoplexy in adolescents.
Jankowski PP, Crawford JR, Khanna P, Malicki DM, Ciacci JD, Levy ML
World Neurosurg 2015 Apr;83(4):644-51. Epub 2014 Dec 18 doi: 10.1016/j.wneu.2014.12.026. PMID: 25527883
The prevalence and natural history of pituitary hemorrhage in prolactinoma.
Sarwar KN, Huda MS, Van de Velde V, Hopkins L, Luck S, Preston R, McGowan BM, Carroll PV, Powrie JK
J Clin Endocrinol Metab 2013 Jun;98(6):2362-7. Epub 2013 Apr 12 doi: 10.1210/jc.2013-1249. PMID: 23585661
Frequency of pituitary tumor apoplexy during treatment of prolactinomas with dopamine agonists: a systematic review.
Carija R, Vucina D
CNS Neurol Disord Drug Targets 2012 Dec;11(8):1012-4. doi: 10.2174/1871527311211080011. PMID: 23244423
Predisposing factors of pituitary hemorrhage.
Liu ZH, Tu PH, Pai PC, Chen NY, Lee ST, Chuang CC
Eur J Neurol 2012 May;19(5):733-8. Epub 2011 Dec 19 doi: 10.1111/j.1468-1331.2011.03619.x. PMID: 22182406
Clinical features and surgical outcome of clinical and subclinical pituitary apoplexy.
Liu ZH, Chang CN, Pai PC, Wei KC, Jung SM, Chen NY, Chuang CC
J Clin Neurosci 2010 Jun;17(6):694-9. Epub 2010 Apr 18 doi: 10.1016/j.jocn.2009.11.012. PMID: 20400318

Diagnosis

Pituitary Apoplexy After Initial Leuprolide Injection.
Fabiano AJ, George S
World Neurosurg 2016 Nov;95:616.e7-616.e9. Epub 2016 Aug 29 doi: 10.1016/j.wneu.2016.08.091. PMID: 27586180
Pituitary tumor apoplexy in adolescents.
Jankowski PP, Crawford JR, Khanna P, Malicki DM, Ciacci JD, Levy ML
World Neurosurg 2015 Apr;83(4):644-51. Epub 2014 Dec 18 doi: 10.1016/j.wneu.2014.12.026. PMID: 25527883
Frequency of pituitary tumor apoplexy during treatment of prolactinomas with dopamine agonists: a systematic review.
Carija R, Vucina D
CNS Neurol Disord Drug Targets 2012 Dec;11(8):1012-4. doi: 10.2174/1871527311211080011. PMID: 23244423
Predisposing factors of pituitary hemorrhage.
Liu ZH, Tu PH, Pai PC, Chen NY, Lee ST, Chuang CC
Eur J Neurol 2012 May;19(5):733-8. Epub 2011 Dec 19 doi: 10.1111/j.1468-1331.2011.03619.x. PMID: 22182406
Clinical features and surgical outcome of clinical and subclinical pituitary apoplexy.
Liu ZH, Chang CN, Pai PC, Wei KC, Jung SM, Chen NY, Chuang CC
J Clin Neurosci 2010 Jun;17(6):694-9. Epub 2010 Apr 18 doi: 10.1016/j.jocn.2009.11.012. PMID: 20400318

Therapy

Pituitary Apoplexy After Initial Leuprolide Injection.
Fabiano AJ, George S
World Neurosurg 2016 Nov;95:616.e7-616.e9. Epub 2016 Aug 29 doi: 10.1016/j.wneu.2016.08.091. PMID: 27586180
Frequency of pituitary tumor apoplexy during treatment of prolactinomas with dopamine agonists: a systematic review.
Carija R, Vucina D
CNS Neurol Disord Drug Targets 2012 Dec;11(8):1012-4. doi: 10.2174/1871527311211080011. PMID: 23244423
Predisposing factors of pituitary hemorrhage.
Liu ZH, Tu PH, Pai PC, Chen NY, Lee ST, Chuang CC
Eur J Neurol 2012 May;19(5):733-8. Epub 2011 Dec 19 doi: 10.1111/j.1468-1331.2011.03619.x. PMID: 22182406
Clinical features and surgical outcome of clinical and subclinical pituitary apoplexy.
Liu ZH, Chang CN, Pai PC, Wei KC, Jung SM, Chen NY, Chuang CC
J Clin Neurosci 2010 Jun;17(6):694-9. Epub 2010 Apr 18 doi: 10.1016/j.jocn.2009.11.012. PMID: 20400318
Pituitary apoplexy after leuprolide.
Davis A, Goel S, Picolos M, Wang M, Lavis V
Pituitary 2006;9(3):263-5. doi: 10.1007/s11102-006-8616-6. PMID: 16832587

Prognosis

When polyuria does not stop: a case report on an unusual complication of hantavirus infection.
Schwab S, Lissmann S, Schäfer N, Isaak A, Klingmüller D, Attenberger U, Eis-Hübinger AM, Hofmann J, Strassburg CP, Lutz P
BMC Infect Dis 2020 Sep 29;20(1):713. doi: 10.1186/s12879-020-05429-1. PMID: 32993515Free PMC Article
Is a stable or decreasing prolactin level in a patient with prolactinoma a surrogate marker for lack of tumor growth?
Alkabbani AG, Mon SY, Hatipoglu B, Kennedy L, Faiman C, Weil RJ, Hamrahian AH
Pituitary 2014 Apr;17(2):97-102. doi: 10.1007/s11102-013-0473-5. PMID: 23468127
Clinical features and surgical outcome of clinical and subclinical pituitary apoplexy.
Liu ZH, Chang CN, Pai PC, Wei KC, Jung SM, Chen NY, Chuang CC
J Clin Neurosci 2010 Jun;17(6):694-9. Epub 2010 Apr 18 doi: 10.1016/j.jocn.2009.11.012. PMID: 20400318
Factors affecting the development of hypothalamus and pituitary lesions in fatal closed head injury: a prospective study.
Chaturvedi D, Suri A, Kasliwal MK, Mahapatra AK, Mehta VS, Shridhar V, Garg A, Sarkar C, Dogra TD, Singh R
J Trauma 2010 Aug;69(2):290-3. doi: 10.1097/TA.0b013e3181b403b5. PMID: 20016386
A retrospective analysis of pituitary apoplexy.
Bills DC, Meyer FB, Laws ER Jr, Davis DH, Ebersold MJ, Scheithauer BW, Ilstrup DM, Abboud CF
Neurosurgery 1993 Oct;33(4):602-8; discussion 608-9. doi: 10.1227/00006123-199310000-00007. PMID: 8232799

Clinical prediction guides

Pituitary apoplexy: a comprehensive analysis of 93 cases across functioning and non-functioning pituitary adenomas from a single-center.
Ragate DC, Memon SS, Lila AR, Sarathi V, Patil VA, Karlekar M, Barnabas R, Thakkar H, Shah NS, Bandgar TR
Pituitary 2024 Oct;27(5):705-713. Epub 2024 Sep 13 doi: 10.1007/s11102-024-01453-5. PMID: 39269545
Pituitary Microadenoma Treated with Individualized Homeopathic Medicine: A Case Report.
Mathur M
Homeopathy 2020 Nov;109(4):243-247. Epub 2020 Aug 30 doi: 10.1055/s-0040-1713383. PMID: 32862414
Pituitary tumor apoplexy in adolescents.
Jankowski PP, Crawford JR, Khanna P, Malicki DM, Ciacci JD, Levy ML
World Neurosurg 2015 Apr;83(4):644-51. Epub 2014 Dec 18 doi: 10.1016/j.wneu.2014.12.026. PMID: 25527883
Central nervous system-related symptoms and findings are common in acute Puumala hantavirus infection.
Hautala T, Mähönen SM, Sironen T, Hautala N, Pääkkö E, Karttunen A, Salmela PI, Ilonen J, Vainio O, Glumoff V, Rytky S, Plyusnin A, Vaheri A, Vapalahti O, Kauma H
Ann Med 2010 Jul;42(5):344-51. doi: 10.3109/07853890.2010.480979. PMID: 20545485
Factors affecting the development of hypothalamus and pituitary lesions in fatal closed head injury: a prospective study.
Chaturvedi D, Suri A, Kasliwal MK, Mahapatra AK, Mehta VS, Shridhar V, Garg A, Sarkar C, Dogra TD, Singh R
J Trauma 2010 Aug;69(2):290-3. doi: 10.1097/TA.0b013e3181b403b5. PMID: 20016386

Recent systematic reviews

Frequency of pituitary tumor apoplexy during treatment of prolactinomas with dopamine agonists: a systematic review.
Carija R, Vucina D
CNS Neurol Disord Drug Targets 2012 Dec;11(8):1012-4. doi: 10.2174/1871527311211080011. PMID: 23244423

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