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Mucinous cystadenoma

MedGen UID:
8222
•Concept ID:
C0010635
•
Neoplastic Process
Synonyms: Cystadenoma, Mucinous; Cystadenomas, Mucinous; Mucinous Cystadenoma; Mucinous Cystadenomas
SNOMED CT: Mucinous cystadenoma (67182003); Mucinous cystoma (67182003); Pseudomucinous cystadenoma (67182003); Mucinous adenoma (33170000)
 
Monarch Initiative: MONDO:0006859

Definition

A benign or low malignant potential cystic epithelial neoplasm composed of cells which contain intracytoplasmic mucin. It may arise from the ovary, pancreas, appendix, and lung. [from NCI]

Professional guidelines

PubMed

Updates in diagnosis and management of pancreatic cysts.
Lee LS
World J Gastroenterol 2021 Sep 14;27(34):5700-5714. doi: 10.3748/wjg.v27.i34.5700. PMID: 34629795Free PMC Article
Mucinous tumors of the ovary: current thoughts on diagnosis and management.
Brown J, Frumovitz M
Curr Oncol Rep 2014 Jun;16(6):389. doi: 10.1007/s11912-014-0389-x. PMID: 24777667Free PMC Article
Cystic and ductal tumors of the pancreas: diagnosis and management.
Scoazec JY, Vullierme MP, Barthet M, Gonzalez JM, Sauvanet A
J Visc Surg 2013 Apr;150(2):69-84. Epub 2013 Mar 19 doi: 10.1016/j.jviscsurg.2013.02.003. PMID: 23518192

Recent clinical studies

Etiology

Mucinous Ovarian Tumors.
Mills AM, Shanes ED
Surg Pathol Clin 2019 Jun;12(2):565-585. doi: 10.1016/j.path.2019.01.008. PMID: 31097115
Cystic Pancreatic Tumors.
Burk KS, Knipp D, Sahani DV
Magn Reson Imaging Clin N Am 2018 Aug;26(3):405-420. doi: 10.1016/j.mric.2018.03.006. PMID: 30376978
ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts.
Elta GH, Enestvedt BK, Sauer BG, Lennon AM
Am J Gastroenterol 2018 Apr;113(4):464-479. Epub 2018 Feb 27 doi: 10.1038/ajg.2018.14. PMID: 29485131
Intraductal papillary mucinous neoplasms and mucinous cystadenomas: current status and recommendations.
Moris M, Wallace MB
Rev Esp Enferm Dig 2017 May;109(5):358-367. doi: 10.17235/reed.2017.4630/2016. PMID: 28112959
Laparoscopic appendectomy.
Agarwala N, Liu CY
J Am Assoc Gynecol Laparosc 2003 May;10(2):166-8. doi: 10.1016/s1074-3804(05)60292-7. PMID: 12732765

Diagnosis

Pancreatic mesothelial cyst.
Chater C, Obeid JO, Mhanna S
BMJ Case Rep 2020 Oct 7;13(10) doi: 10.1136/bcr-2020-236255. PMID: 33028569Free PMC Article
Mucinous Ovarian Tumors.
Mills AM, Shanes ED
Surg Pathol Clin 2019 Jun;12(2):565-585. doi: 10.1016/j.path.2019.01.008. PMID: 31097115
Mucinous Cystadenoma in Children and Adolescents.
Cowan RA, Haber EN, Faucz FR, Stratakis CA, Gomez-Lobo V
J Pediatr Adolesc Gynecol 2017 Aug;30(4):495-498. Epub 2017 Feb 16 doi: 10.1016/j.jpag.2017.02.001. PMID: 28216128Free PMC Article
Intraductal papillary mucinous neoplasms and mucinous cystadenomas: current status and recommendations.
Moris M, Wallace MB
Rev Esp Enferm Dig 2017 May;109(5):358-367. doi: 10.17235/reed.2017.4630/2016. PMID: 28112959
Mucinous tumors of the ovary: current thoughts on diagnosis and management.
Brown J, Frumovitz M
Curr Oncol Rep 2014 Jun;16(6):389. doi: 10.1007/s11912-014-0389-x. PMID: 24777667Free PMC Article

Therapy

Advanced endoscopic ultrasound management techniques for preneoplastic pancreatic cystic lesions.
Arshad HM, Bharmal S, Duman DG, Liangpunsakul S, Turner BG
J Investig Med 2017 Jan;65(1):7-14. Epub 2016 Aug 29 doi: 10.1136/jim-2016-000167. PMID: 27574295Free PMC Article
Endoscopic ultrasound-guided pancreatic cyst ablation.
DeWitt J
Gastrointest Endosc Clin N Am 2012 Apr;22(2):291-302, ix-x. Epub 2012 Apr 23 doi: 10.1016/j.giec.2012.04.001. PMID: 22632951
Spleen-preserving distal pancreatectomy.
Lee SY, Goh BK, Tan YM, Chung YF, Cheow PC, Chow PK, Wong WK, Ooi LL
Singapore Med J 2008 Nov;49(11):883-5. PMID: 19037554
Tracheobronchial gland tumors.
Gaissert HA, Mark EJ
Cancer Control 2006 Oct;13(4):286-94. doi: 10.1177/107327480601300406. PMID: 17075566
Laparoscopic appendectomy.
Agarwala N, Liu CY
J Am Assoc Gynecol Laparosc 2003 May;10(2):166-8. doi: 10.1016/s1074-3804(05)60292-7. PMID: 12732765

Prognosis

Mucinous Cystadenoma of the Urachus and Review of Current Classification of Urachal Mucinous Cystic Neoplasms.
Wang D, Sule N
Arch Pathol Lab Med 2019 Feb;143(2):258-263. Epub 2018 Nov 6 doi: 10.5858/arpa.2017-0319-RS. PMID: 30398914
Intraductal papillary mucinous neoplasms and mucinous cystadenomas: current status and recommendations.
Moris M, Wallace MB
Rev Esp Enferm Dig 2017 May;109(5):358-367. doi: 10.17235/reed.2017.4630/2016. PMID: 28112959
Precancerous lesions of the pancreas.
Zamboni G, Hirabayashi K, Castelli P, Lennon AM
Best Pract Res Clin Gastroenterol 2013 Apr;27(2):299-322. doi: 10.1016/j.bpg.2013.04.001. PMID: 23809247
Mucinous cystic neoplasms.
Fernández-del Castillo C
J Gastrointest Surg 2008 Mar;12(3):411-3. Epub 2007 Oct 23 doi: 10.1007/s11605-007-0347-0. PMID: 17955316
Laparoscopic appendectomy.
Agarwala N, Liu CY
J Am Assoc Gynecol Laparosc 2003 May;10(2):166-8. doi: 10.1016/s1074-3804(05)60292-7. PMID: 12732765

Clinical prediction guides

ABCD1 as a Novel Diagnostic Marker for Solid Pseudopapillary Neoplasm of the Pancreas.
Liu YA, Liu Y, Tu J, Shi Y, Pang J, Huang Q, Wang X, Lin Z, Zhao Y, Wang W, Peng J, Wu W
Am J Surg Pathol 2024 May 1;48(5):511-520. Epub 2024 Apr 3 doi: 10.1097/PAS.0000000000002205. PMID: 38567813Free PMC Article
Histological and Genetic Diversity in Ovarian Mucinous Carcinomas: A Pilot Study.
Razia S, Nakayama K, Yamashita H, Ishibashi T, Ishikawa M, Kanno K, Sato S, Kyo S
Curr Oncol 2023 Apr 4;30(4):4052-4059. doi: 10.3390/curroncol30040307. PMID: 37185420Free PMC Article
Therapeutic Approach to Cystic Neoplasms of the Pancreas.
Al Efishat M, Allen PJ
Surg Oncol Clin N Am 2016 Apr;25(2):351-61. doi: 10.1016/j.soc.2015.11.006. PMID: 27013369Free PMC Article
Morphologic, Immunophenotypic, and Molecular Features of Epithelial Ovarian Cancer.
Ramalingam P
Oncology (Williston Park) 2016 Feb;30(2):166-76. PMID: 26892153
Spleen-preserving distal pancreatectomy.
Lee SY, Goh BK, Tan YM, Chung YF, Cheow PC, Chow PK, Wong WK, Ooi LL
Singapore Med J 2008 Nov;49(11):883-5. PMID: 19037554

Recent systematic reviews

Simple mucinous cyst: another potential cancer precursor in the pancreas? Case report with molecular characterization and systematic review of the literature.
Milanetto AC, Tonello AS, Valotto G, Munari G, Luchini C, Fassan M, Pasquali C
Virchows Arch 2021 Jul;479(1):179-189. Epub 2021 Jan 28 doi: 10.1007/s00428-021-03029-1. PMID: 33511431Free PMC Article
Ovarian hydatid cyst - systematic review of clinicopathological and immunohistochemical characteristics of an unusual entity.
Lozneanu L, Balan RA, Giuşcă SE, Căruntu ID, Amălinei C, Grigoraş A
Rom J Morphol Embryol 2019;60(3):751-759. PMID: 31912083
Clinicopathological Features and Management of Appendiceal Mucoceles: A Systematic Review.
Morano WF, Gleeson EM, Sullivan SH, Padmanaban V, Mapow BL, Shewokis PA, Esquivel J, Bowne WB
Am Surg 2018 Feb 1;84(2):273-281. PMID: 29580358

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