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Reactive airway disease

MedGen UID:
811342
•Concept ID:
C3714497
•
Disease or Syndrome
Synonyms: Hyperactive Airway Disease; hyperactive airway disease; Reactive Airway Disease; reactive airway disease; reactive airway disease (AQ)
SNOMED CT: Reactive airway disease (991000119106)
 
Monarch Initiative: MONDO:0100470

Definition

Coughing, wheezing, or shortness of breath that is triggered by allergens, infection, or other irritants. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReactive airway disease

Professional guidelines

PubMed

Emergency management and asthma risk in young Medicaid-enrolled children with recurrent wheeze.
Hardee IJ, Zaniletti I, Tanverdi MS, Liu AH, Mistry RD, Navanandan N
J Asthma 2024 Sep;61(9):951-958. Epub 2024 Feb 12 doi: 10.1080/02770903.2024.2314623. PMID: 38324665Free PMC Article
Burden and emergency department management of acute cough in children.
Anderson-James S, Marchant JM, Chang AB, Acworth JP, Phillips NT, Drescher BJ, Goyal V, O'Grady KF
J Paediatr Child Health 2019 Feb;55(2):181-187. Epub 2018 Aug 1 doi: 10.1111/jpc.14146. PMID: 30066972
Diagnosis and treatment of paradoxical vocal fold motion in infants.
O'Connell Ferster AP, Shokri T, Carr M
Int J Pediatr Otorhinolaryngol 2018 Apr;107:6-9. Epub 2018 Feb 20 doi: 10.1016/j.ijporl.2018.01.027. PMID: 29501313

Recent clinical studies

Etiology

Bacillus Calmette-Guérin vaccination as defense against SARS-CoV-2 (BADAS): a randomized controlled trial to protect healthcare workers in the USA by enhanced trained immune responses.
DiNardo AR, Arditi M, Kamat AM, Koster KJ, Carrero S, Nishiguchi T, Lebedev M, Benjamin AB, Avalos P, Lozano M, Moule MG, McCune B, Herron B, Ladki M, Sheikh D, Spears M, Herrejon IA, Dodge C, Kumar S, Hutchison RW, Ofili TU, Opperman LA, Bernard JA, Lerner SP, Udeani G, Neal G, Netea MG, Cirillo JD
Trials 2023 Oct 4;24(1):636. doi: 10.1186/s13063-023-07662-w. PMID: 37794431Free PMC Article
Bronchopulmonary dysplasia.
Schmidt AR, Ramamoorthy C
Paediatr Anaesth 2022 Feb;32(2):174-180. Epub 2021 Dec 15 doi: 10.1111/pan.14365. PMID: 34877749
Clinical Outcomes for Young Children Diagnosed With Asthma Versus Reactive Airway Disease.
Frey SM, Goldstein NPN, Kwiatkowski V, Reinish A
Acad Pediatr 2022 Jan-Feb;22(1):37-46. Epub 2021 Jun 18 doi: 10.1016/j.acap.2021.06.009. PMID: 34153535
Obesity-related asthma in adults.
Bhatt NA, Lazarus A
Postgrad Med 2016 Aug;128(6):563-6. Epub 2016 Jul 7 doi: 10.1080/00325481.2016.1204211. PMID: 27336439
Enalapril-induced cough.
Gibson GR
Arch Intern Med 1989 Dec;149(12):2701-3. PMID: 2556977

Diagnosis

Bronchopulmonary dysplasia.
Schmidt AR, Ramamoorthy C
Paediatr Anaesth 2022 Feb;32(2):174-180. Epub 2021 Dec 15 doi: 10.1111/pan.14365. PMID: 34877749
Clinical Outcomes for Young Children Diagnosed With Asthma Versus Reactive Airway Disease.
Frey SM, Goldstein NPN, Kwiatkowski V, Reinish A
Acad Pediatr 2022 Jan-Feb;22(1):37-46. Epub 2021 Jun 18 doi: 10.1016/j.acap.2021.06.009. PMID: 34153535
Methacrylate perspective in current dental practice.
Bishop S, Roberts H
J Esthet Restor Dent 2020 Oct;32(7):673-680. Epub 2020 Aug 3 doi: 10.1111/jerd.12633. PMID: 32744420
Respiratory Considerations Including Airway and Ventilation Issues in Critical Care Obstetric Patients.
Ende H, Varelmann D
Obstet Gynecol Clin North Am 2016 Dec;43(4):699-708. doi: 10.1016/j.ogc.2016.07.002. PMID: 27816155
Regadenoson.
Bengalorkar GM, Bhuvana K, Sarala N, Kumar TN
J Postgrad Med 2012 Apr-Jun;58(2):140-6. doi: 10.4103/0022-3859.97177. PMID: 22718059

Therapy

Bacillus Calmette-Guérin vaccination as defense against SARS-CoV-2 (BADAS): a randomized controlled trial to protect healthcare workers in the USA by enhanced trained immune responses.
DiNardo AR, Arditi M, Kamat AM, Koster KJ, Carrero S, Nishiguchi T, Lebedev M, Benjamin AB, Avalos P, Lozano M, Moule MG, McCune B, Herron B, Ladki M, Sheikh D, Spears M, Herrejon IA, Dodge C, Kumar S, Hutchison RW, Ofili TU, Opperman LA, Bernard JA, Lerner SP, Udeani G, Neal G, Netea MG, Cirillo JD
Trials 2023 Oct 4;24(1):636. doi: 10.1186/s13063-023-07662-w. PMID: 37794431Free PMC Article
Stimulants and the lung : review of literature.
Tseng W, Sutter ME, Albertson TE
Clin Rev Allergy Immunol 2014 Feb;46(1):82-100. doi: 10.1007/s12016-013-8376-9. PMID: 23760760
Regadenoson.
Bengalorkar GM, Bhuvana K, Sarala N, Kumar TN
J Postgrad Med 2012 Apr-Jun;58(2):140-6. doi: 10.4103/0022-3859.97177. PMID: 22718059
Enalapril-induced cough.
Gibson GR
Arch Intern Med 1989 Dec;149(12):2701-3. PMID: 2556977
Comparison of ophthalmic beta-blocking agents.
Lesar TS
Clin Pharm 1987 Jun;6(6):451-63. PMID: 2891463

Prognosis

Bacillus Calmette-Guérin vaccination as defense against SARS-CoV-2 (BADAS): a randomized controlled trial to protect healthcare workers in the USA by enhanced trained immune responses.
DiNardo AR, Arditi M, Kamat AM, Koster KJ, Carrero S, Nishiguchi T, Lebedev M, Benjamin AB, Avalos P, Lozano M, Moule MG, McCune B, Herron B, Ladki M, Sheikh D, Spears M, Herrejon IA, Dodge C, Kumar S, Hutchison RW, Ofili TU, Opperman LA, Bernard JA, Lerner SP, Udeani G, Neal G, Netea MG, Cirillo JD
Trials 2023 Oct 4;24(1):636. doi: 10.1186/s13063-023-07662-w. PMID: 37794431Free PMC Article
First Time Wheezing in a 2-Year-Old.
Viehl L, Estabrook M, Bhalla S, Lee C, Kemp J, White A
Pediatrics 2021 Jul;148(1) Epub 2021 Jun 22 doi: 10.1542/peds.2020-042085. PMID: 34158315
Mediastinal Lymphadenopathy in Children With Histoplasmosis.
Staszak JK, Zmijewski P, Arnold S, Bagga B, Williams RF
J Surg Res 2019 Dec;244:558-565. Epub 2019 Jul 25 doi: 10.1016/j.jss.2019.06.062. PMID: 31352234
Thoracoscopic diaphragmatic plication.
Guy TS, Montany PF
Surg Laparosc Endosc 1998 Aug;8(4):319-21. PMID: 9703610
Special features of asthma in children.
Cropp GJ
Chest 1985 Jan;87(1 Suppl):55S-62S. doi: 10.1378/chest.87.1.55s. PMID: 3880532Free PMC Article

Clinical prediction guides

Bacillus Calmette-Guérin vaccination as defense against SARS-CoV-2 (BADAS): a randomized controlled trial to protect healthcare workers in the USA by enhanced trained immune responses.
DiNardo AR, Arditi M, Kamat AM, Koster KJ, Carrero S, Nishiguchi T, Lebedev M, Benjamin AB, Avalos P, Lozano M, Moule MG, McCune B, Herron B, Ladki M, Sheikh D, Spears M, Herrejon IA, Dodge C, Kumar S, Hutchison RW, Ofili TU, Opperman LA, Bernard JA, Lerner SP, Udeani G, Neal G, Netea MG, Cirillo JD
Trials 2023 Oct 4;24(1):636. doi: 10.1186/s13063-023-07662-w. PMID: 37794431Free PMC Article
Association of Asthma With Treatments and Outcomes in Children With Critical Influenza.
Maddux AB, Grunwell JR, Newhams MM, Chen SR, Olson SM, Halasa NB, Weiss SL, Coates BM, Schuster JE, Hall MW, Nofziger RA, Flori HR, Gertz SJ, Kong M, Sanders RC Jr, Irby K, Hume JR, Cullimore ML, Shein SL, Thomas NJ, Miller K, Patel M, Fitzpatrick AM, Phipatanakul W, Randolph AG; PALISI Pediatric Intensive Care Influenza Network Investigators
J Allergy Clin Immunol Pract 2023 Mar;11(3):836-843.e3. Epub 2022 Nov 12 doi: 10.1016/j.jaip.2022.10.045. PMID: 36379408Free PMC Article
Clinical presentation of paradoxical vocal fold motion or laryngeal dyskinesia in infants.
So RJ, Jenks C, Yi J, Ryan MA, Tunkel DE, Walsh JM
Int J Pediatr Otorhinolaryngol 2022 Nov;162:111304. Epub 2022 Sep 2 doi: 10.1016/j.ijporl.2022.111304. PMID: 36084476
Avoiding unnecessary bronchoscopy in children with suspected foreign body aspiration using computed tomography.
Gibbons AT, Casar Berazaluce AM, Hanke RE, McNinch NL, Person A, Mehlman T, Rubin M, Ponsky TA
J Pediatr Surg 2020 Jan;55(1):176-181. Epub 2019 Oct 25 doi: 10.1016/j.jpedsurg.2019.09.045. PMID: 31706607
Pulmonary hypertension in giant omphalocele infants.
Partridge EA, Hanna BD, Panitch HB, Rintoul NE, Peranteau WH, Flake AW, Scott Adzick N, Hedrick HL
J Pediatr Surg 2014 Dec;49(12):1767-70. Epub 2014 Nov 14 doi: 10.1016/j.jpedsurg.2014.09.016. PMID: 25487480

Recent systematic reviews

The effects of macrolides in children with reactive airway disease: a systematic review and meta-analysis of randomized controlled trials.
Lei WT, Lin HH, Tsai MC, Hung HH, Cheng YJ, Liu SJ, Lin CY, Yeh TL
Drug Des Devel Ther 2018;12:3825-3845. Epub 2018 Nov 8 doi: 10.2147/DDDT.S183527. PMID: 30510399Free PMC Article
Multiple versus single doses of exogenous surfactant for the prevention or treatment of neonatal respiratory distress syndrome.
Soll R, Ozek E
Cochrane Database Syst Rev 2009 Jan 21;(1):CD000141. doi: 10.1002/14651858.CD000141.pub2. PMID: 19160177
Safety profile of pneumococcal conjugate vaccines: systematic review of pre- and post-licensure data.
Destefano F, Pfeifer D, Nohynek H
Bull World Health Organ 2008 May;86(5):373-80. doi: 10.2471/blt.07.048025. PMID: 18545740Free PMC Article

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