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Childhood Acute Monocytic Leukemia

MedGen UID:
79021
•Concept ID:
C0279646
•
Neoplastic Process
Synonyms: Childhood Acute Differentiated Monocytic Leukemia (M5b); Childhood Acute M5b Leukemia; Childhood Acute Monocytic Leukemia with Differentiation; M5b Childhood Acute Differentiated Monocytic Leukemia; M5b Pediatric Acute Differentiated Monocytic Leukemia; Pediatric Acute Differentiated Monocytic Leukemia; Pediatric Acute M5b Leukemia; Pediatric Acute Monocytic Leukemia with Differentiation

Definition

An acute monocytic leukemia occurring in children. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood Acute Monocytic Leukemia

Professional guidelines

PubMed

Recent advances in the pathogenesis and treatment of juvenile myelomonocytic leukaemia.
Loh ML
Br J Haematol 2011 Mar;152(6):677-87. doi: 10.1111/j.1365-2141.2010.08525.x. PMID: 21623760
Childhood myelodysplastic syndrome: focus on the approach to diagnosis and treatment of juvenile myelomonocytic leukemia.
Loh ML
Hematology Am Soc Hematol Educ Program 2010;2010:357-62. doi: 10.1182/asheducation-2010.1.357. PMID: 21239819
Treatment of acute leukemia in adults.
Clarkson BD, Dowling MD, Gee TS, Cunningham IB, Burchenal JH
Cancer 1975 Aug;36(2):775-95. doi: 10.1002/1097-0142(197508)36:2+<775::aid-cncr2820360824>3.0.co;2-v. PMID: 1057450

Recent clinical studies

Therapy

Acute monocytic leukemia in children. Response to VP-16-213 as a single agent.
Nishikawa A, Nakamura Y, Nobori U, Aoki T, Higashino H, Matsui T, Kobayashi Y, Yamashita M, Unishi G
Cancer 1987 Nov 1;60(9):2146-9. doi: 10.1002/1097-0142(19871101)60:9<2146::aid-cncr2820600904>3.0.co;2-n. PMID: 3326651

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