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Swyer James Syndrome

MedGen UID:
78107
•Concept ID:
C0264395
•
Disease or Syndrome
Synonyms: MacLeod Syndrome; Swyer-James Syndrome; Syndrome, MacLeod; Syndrome, Swyer-James

Definition

A rare syndrome characterized by the presence of a small lung as a result of unilateral post-infectious bronchiolitis obliterans. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSwyer James Syndrome

Professional guidelines

PubMed

Clinical management and outcome of childhood lung abscess: a 16-year experience.
Chan PC, Huang LM, Wu PS, Chang PY, Yang TT, Lu CY, Lee PI, Chen JM, Lee CY, Chang LY
J Microbiol Immunol Infect 2005 Jun;38(3):183-8. PMID: 15986068

Recent clinical studies

Etiology

Swyer-James Syndrome.
Hamada K, Oishi K, Hirano T, Shiinoki T, Shibuya K, Matsunaga K
Am J Respir Crit Care Med 2018 Jan 1;197(1):130-131. doi: 10.1164/rccm.201708-1691IM. PMID: 29064268
Anesthetic implications for patients with Swyer-James syndrome.
Smith MM, Barbara DW, Smith BC, Sprung J, Weingarten TN
J Cardiothorac Vasc Anesth 2014 Aug;28(4):925-30. Epub 2013 Sep 12 doi: 10.1053/j.jvca.2013.03.039. PMID: 24035065
Recurrent pneumothorax related to Swyer-James syndrome.
Sano A, Fukami T, Murakawa T, Nakajima J
Ann Thorac Cardiovasc Surg 2014;20 Suppl:539-41. Epub 2013 Feb 15 doi: 10.5761/atcs.cr.12.02102. PMID: 23411839
Swyer-James syndrome: CT findings in eight patients.
Moore AD, Godwin JD, Dietrich PA, Verschakelen JA, Henderson WR Jr
AJR Am J Roentgenol 1992 Jun;158(6):1211-5. doi: 10.2214/ajr.158.6.1590109. PMID: 1590109
CT findings in Swyer-James syndrome.
Marti-Bonmati L, Ruiz Perales F, Catala F, Mata JM, Calonge E
Radiology 1989 Aug;172(2):477-80. doi: 10.1148/radiology.172.2.2748829. PMID: 2748829

Diagnosis

Expiratory CT scan: When to do it and how to interpret it.
Martínez de Alegría Alonso A, Bermúdez Naveira A, Uceda Navarro D, Domínguez Robla M
Radiologia (Engl Ed) 2023 Jul-Aug;65(4):352-361. Epub 2023 Jul 12 doi: 10.1016/j.rxeng.2023.01.008. PMID: 37516488
Swyer-James Syndrome.
Hamada K, Oishi K, Hirano T, Shiinoki T, Shibuya K, Matsunaga K
Am J Respir Crit Care Med 2018 Jan 1;197(1):130-131. doi: 10.1164/rccm.201708-1691IM. PMID: 29064268
Anesthetic implications for patients with Swyer-James syndrome.
Smith MM, Barbara DW, Smith BC, Sprung J, Weingarten TN
J Cardiothorac Vasc Anesth 2014 Aug;28(4):925-30. Epub 2013 Sep 12 doi: 10.1053/j.jvca.2013.03.039. PMID: 24035065
Swyer-James syndrome.
Gopinath A, Strigun D, Banyopadhyay T
Conn Med 2005 Jun-Jul;69(6):325-7. PMID: 16184857
Swyer-James syndrome.
Chalmers JH Jr
Semin Respir Infect 1999 Sep;14(3):295-7. PMID: 10501317

Therapy

Obstructive bronchiolar disease identified by CT in the non-transplant population: analysis of 29 consecutive cases.
Parambil JG, Yi ES, Ryu JH
Respirology 2009 Apr;14(3):443-8. Epub 2008 Dec 16 doi: 10.1111/j.1440-1843.2008.01445.x. PMID: 19210653
Unilateral pulmonary edema in Swyer-James syndrome.
Saleh M, Miles AI, Lasser RP
Chest 1974 Nov;66(5):594-7. doi: 10.1378/chest.66.5.594. PMID: 4430215

Prognosis

Swyer-James Syndrome.
Hamada K, Oishi K, Hirano T, Shiinoki T, Shibuya K, Matsunaga K
Am J Respir Crit Care Med 2018 Jan 1;197(1):130-131. doi: 10.1164/rccm.201708-1691IM. PMID: 29064268
Anesthetic implications for patients with Swyer-James syndrome.
Smith MM, Barbara DW, Smith BC, Sprung J, Weingarten TN
J Cardiothorac Vasc Anesth 2014 Aug;28(4):925-30. Epub 2013 Sep 12 doi: 10.1053/j.jvca.2013.03.039. PMID: 24035065
Recurrent pneumothorax related to Swyer-James syndrome.
Sano A, Fukami T, Murakawa T, Nakajima J
Ann Thorac Cardiovasc Surg 2014;20 Suppl:539-41. Epub 2013 Feb 15 doi: 10.5761/atcs.cr.12.02102. PMID: 23411839
Swyer-James syndrome with peculiar course and ipsilateral pulmonary vein defect.
Chong B, Xiao-Lian S, Hui S, Xiao-Peng Y, Qiang L
Intern Med 2011;50(17):1829-33. Epub 2011 Sep 1 doi: 10.2169/internalmedicine.50.4151. PMID: 21881283
Swyer-James Syndrome with finger clubbing after severe measles infection.
Kim CK, Koh JY, Han YS, Kang H, Kim JS, Koh YY
Pediatr Int 2008 Jun;50(3):413-5. doi: 10.1111/j.1442-200X.2008.02597.x. PMID: 18533964

Clinical prediction guides

Recurrent pneumothorax related to Swyer-James syndrome.
Sano A, Fukami T, Murakawa T, Nakajima J
Ann Thorac Cardiovasc Surg 2014;20 Suppl:539-41. Epub 2013 Feb 15 doi: 10.5761/atcs.cr.12.02102. PMID: 23411839
Etiopathologies associated with intercostal muscle hypermetabolism and prominent right ventricle visualization on 2-deoxy-2[F-18]fluoro-D-glucose-positron emission tomography: significance of an incidental finding and in the setting of a known pulmonary disease.
Basu S, Alzeair S, Li G, Dadparvar S, Alavi A
Mol Imaging Biol 2007 Nov-Dec;9(6):333-9. doi: 10.1007/s11307-007-0102-7. PMID: 17610018
46,XY pure gonadal dysgenesis (Swyer-James syndrome)--Y or Y not?: a review.
Guidozzi F, Ball J, Spurdle A
Obstet Gynecol Surv 1994 Feb;49(2):138-46. doi: 10.1097/00006254-199402000-00026. PMID: 8164912

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