U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Multifocal Atrial Premature Complex by ECG Finding

MedGen UID:
769517
•Concept ID:
C3640877
•
Finding
Synonyms: Multifocal Atrial Premature Complex; Multifocal Atrial Premature Complex by EKG Finding

Definition

An electrocardiographic finding of premature atrial complexes which have 2 or more distinct morphologies, suggesting origin at more than one atrial site. (CDISC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMultifocal Atrial Premature Complex by ECG Finding

Recent clinical studies

Etiology

Risk of cardiac arrhythmias after electrical accident: a single-center study of 480 patients.
Pilecky D, Vamos M, Bogyi P, Muk B, Stauder D, Racz H, Nyolczas N, Duray GZ, Zacher G, Zima E
Clin Res Cardiol 2019 Aug;108(8):901-908. Epub 2019 Feb 15 doi: 10.1007/s00392-019-01420-2. PMID: 30771067Free PMC Article
Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Na(v)1.5 gain-of-function mutation (G213D).
Calloe K, Broendberg AK, Christensen AH, Pedersen LN, Olesen MS, de Los Angeles Tejada M, Friis S, Thomsen MB, Bundgaard H, Jensen HK
Int J Cardiol 2018 Apr 15;257:160-167. doi: 10.1016/j.ijcard.2017.11.095. PMID: 29506689
Electrocardiographic abnormalities in patients receiving hemodialysis.
Abe S, Yoshizawa M, Nakanishi N, Yazawa T, Yokota K, Honda M, Sloman G
Am Heart J 1996 Jun;131(6):1137-44. doi: 10.1016/s0002-8703(96)90088-5. PMID: 8644592
Arrhythmia during extracorporeal shock wave lithotripsy.
Zeng ZR, Lindstedt E, Roijer A, Olsson SB
Br J Urol 1993 Jan;71(1):10-6. doi: 10.1111/j.1464-410x.1993.tb15871.x. PMID: 8435716
Cardiac arrhythmias during theophylline toxicity. A prospective continuous electrocardiographic study.
Sessler CN, Cohen MD
Chest 1990 Sep;98(3):672-8. doi: 10.1378/chest.98.3.672. PMID: 2394145

Diagnosis

Incessant multiform ectopy in a young woman: What is the mechanism and treatment?
Rosenthal DG, Lee BK, Scheinman MM
Heart Rhythm 2021 Sep;18(9):1615-1616. doi: 10.1016/j.hrthm.2021.05.027. PMID: 34474745
Risk of cardiac arrhythmias after electrical accident: a single-center study of 480 patients.
Pilecky D, Vamos M, Bogyi P, Muk B, Stauder D, Racz H, Nyolczas N, Duray GZ, Zacher G, Zima E
Clin Res Cardiol 2019 Aug;108(8):901-908. Epub 2019 Feb 15 doi: 10.1007/s00392-019-01420-2. PMID: 30771067Free PMC Article
Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Na(v)1.5 gain-of-function mutation (G213D).
Calloe K, Broendberg AK, Christensen AH, Pedersen LN, Olesen MS, de Los Angeles Tejada M, Friis S, Thomsen MB, Bundgaard H, Jensen HK
Int J Cardiol 2018 Apr 15;257:160-167. doi: 10.1016/j.ijcard.2017.11.095. PMID: 29506689
Arrhythmias Seen in Baseline 24-Hour Holter ECG Recordings in Healthy Normal Volunteers During Phase 1 Clinical Trials.
Hingorani P, Karnad DR, Rohekar P, Kerkar V, Lokhandwala YY, Kothari S
J Clin Pharmacol 2016 Jul;56(7):885-93. Epub 2016 Jan 11 doi: 10.1002/jcph.679. PMID: 26626443
Electrocardiographic abnormalities in patients receiving hemodialysis.
Abe S, Yoshizawa M, Nakanishi N, Yazawa T, Yokota K, Honda M, Sloman G
Am Heart J 1996 Jun;131(6):1137-44. doi: 10.1016/s0002-8703(96)90088-5. PMID: 8644592

Therapy

Incessant multiform ectopy in a young woman: What is the mechanism and treatment?
Rosenthal DG, Lee BK, Scheinman MM
Heart Rhythm 2021 Sep;18(9):1615-1616. doi: 10.1016/j.hrthm.2021.05.027. PMID: 34474745
Novel SCN5A mutation in amiodarone-responsive multifocal ventricular ectopy-associated cardiomyopathy.
Beckermann TM, McLeod K, Murday V, Potet F, George AL Jr
Heart Rhythm 2014 Aug;11(8):1446-53. Epub 2014 May 9 doi: 10.1016/j.hrthm.2014.04.042. PMID: 24815523Free PMC Article
Electrocardiographic abnormalities in patients receiving hemodialysis.
Abe S, Yoshizawa M, Nakanishi N, Yazawa T, Yokota K, Honda M, Sloman G
Am Heart J 1996 Jun;131(6):1137-44. doi: 10.1016/s0002-8703(96)90088-5. PMID: 8644592
Arrhythmia during extracorporeal shock wave lithotripsy.
Zeng ZR, Lindstedt E, Roijer A, Olsson SB
Br J Urol 1993 Jan;71(1):10-6. doi: 10.1111/j.1464-410x.1993.tb15871.x. PMID: 8435716
Cardiac arrhythmias during theophylline toxicity. A prospective continuous electrocardiographic study.
Sessler CN, Cohen MD
Chest 1990 Sep;98(3):672-8. doi: 10.1378/chest.98.3.672. PMID: 2394145

Prognosis

Risk of cardiac arrhythmias after electrical accident: a single-center study of 480 patients.
Pilecky D, Vamos M, Bogyi P, Muk B, Stauder D, Racz H, Nyolczas N, Duray GZ, Zacher G, Zima E
Clin Res Cardiol 2019 Aug;108(8):901-908. Epub 2019 Feb 15 doi: 10.1007/s00392-019-01420-2. PMID: 30771067Free PMC Article
Novel SCN5A mutation in amiodarone-responsive multifocal ventricular ectopy-associated cardiomyopathy.
Beckermann TM, McLeod K, Murday V, Potet F, George AL Jr
Heart Rhythm 2014 Aug;11(8):1446-53. Epub 2014 May 9 doi: 10.1016/j.hrthm.2014.04.042. PMID: 24815523Free PMC Article
Incidence of arrhythmias in normal pregnancy and relation to palpitations, dizziness, and syncope.
Shotan A, Ostrzega E, Mehra A, Johnson JV, Elkayam U
Am J Cardiol 1997 Apr 15;79(8):1061-4. doi: 10.1016/s0002-9149(97)00047-7. PMID: 9114764
Electrocardiographic abnormalities in patients receiving hemodialysis.
Abe S, Yoshizawa M, Nakanishi N, Yazawa T, Yokota K, Honda M, Sloman G
Am Heart J 1996 Jun;131(6):1137-44. doi: 10.1016/s0002-8703(96)90088-5. PMID: 8644592

Clinical prediction guides

Risk of cardiac arrhythmias after electrical accident: a single-center study of 480 patients.
Pilecky D, Vamos M, Bogyi P, Muk B, Stauder D, Racz H, Nyolczas N, Duray GZ, Zacher G, Zima E
Clin Res Cardiol 2019 Aug;108(8):901-908. Epub 2019 Feb 15 doi: 10.1007/s00392-019-01420-2. PMID: 30771067Free PMC Article
Arrhythmias Seen in Baseline 24-Hour Holter ECG Recordings in Healthy Normal Volunteers During Phase 1 Clinical Trials.
Hingorani P, Karnad DR, Rohekar P, Kerkar V, Lokhandwala YY, Kothari S
J Clin Pharmacol 2016 Jul;56(7):885-93. Epub 2016 Jan 11 doi: 10.1002/jcph.679. PMID: 26626443
Novel SCN5A mutation in amiodarone-responsive multifocal ventricular ectopy-associated cardiomyopathy.
Beckermann TM, McLeod K, Murday V, Potet F, George AL Jr
Heart Rhythm 2014 Aug;11(8):1446-53. Epub 2014 May 9 doi: 10.1016/j.hrthm.2014.04.042. PMID: 24815523Free PMC Article
Electrophysiologic characteristics of the spontaneous onset and termination of atrial fibrillation.
Ndrepepa G, Weber S, Karch MR, Schneider MA, Schreieck J Jü, Schömig A, Schmitt C
Am J Cardiol 2002 Dec 1;90(11):1215-20. doi: 10.1016/s0002-9149(02)02837-0. PMID: 12450601
Detection of arrhythmias in a representative sample of the Athens population.
Diamantopoulos EJ, Anthopoulos L, Nanas S, Maliaras G, Chrisos D, Moulopoulos SD
Eur Heart J 1987 Aug;8 Suppl D:17-9. doi: 10.1093/eurheartj/8.suppl_d.17. PMID: 2445570

Supplemental Content

Table of contents

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...