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Basal cell carcinoma, susceptibility to, 7(BCC7)

MedGen UID:
766520
Concept ID:
C3553606
Finding
Synonym: BCC7
 
Gene (location): TP53 (17p13.1)
 
Monarch Initiative: MONDO:0013876
OMIM®: 614740

Definition

Any skin basal cell carcinoma in which the cause of the disease is a mutation in the TP53 gene. [from MONDO]

Professional guidelines

PubMed

Berlin NL, Cartmel B, Leffell DJ, Bale AE, Mayne ST, Ferrucci LM
Cancer Epidemiol 2015 Dec;39(6):1078-83. Epub 2015 Sep 14 doi: 10.1016/j.canep.2015.09.005. PMID: 26381319Free PMC Article
Molinaro AM, Ferrucci LM, Cartmel B, Loftfield E, Leffell DJ, Bale AE, Mayne ST
Am J Epidemiol 2015 Jun 1;181(11):908-16. Epub 2015 Apr 8 doi: 10.1093/aje/kwu356. PMID: 25858289Free PMC Article
Carless MA, Lea RA, Curran JE, Appleyard B, Gaffney P, Green A, Griffiths LR
J Invest Dermatol 2002 Dec;119(6):1373-8. doi: 10.1046/j.1523-1747.2002.19646.x. PMID: 12485442

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Basal Cell Skin Cancer, 2023

Recent clinical studies

Etiology

Patil P, Pencheva BB, Patil VM, Fangusaro J
Neurotherapeutics 2022 Oct;19(6):1752-1771. Epub 2022 Sep 2 doi: 10.1007/s13311-022-01277-w. PMID: 36056180Free PMC Article
Vanderbeck K, Orr CE, Parvinnejad N, Wang T, Bradshaw S, Wang A, Asai Y
J Cutan Pathol 2021 Jul;48(7):877-883. Epub 2021 Feb 18 doi: 10.1111/cup.13975. PMID: 33543489
Kasumagic-Halilovic E, Hasic M, Ovcina-Kurtovic N
Med Arch 2019 Dec;73(6):394-398. doi: 10.5455/medarh.2019.73.394-398. PMID: 32082007Free PMC Article
Stacey SN, Helgason H, Gudjonsson SA, Thorleifsson G, Zink F, Sigurdsson A, Kehr B, Gudmundsson J, Sulem P, Sigurgeirsson B, Benediktsdottir KR, Thorisdottir K, Ragnarsson R, Fuentelsaz V, Corredera C, Gilaberte Y, Grasa M, Planelles D, Sanmartin O, Rudnai P, Gurzau E, Koppova K, Nexø BA, Tjønneland A, Overvad K, Jonasson JG, Tryggvadottir L, Johannsdottir H, Kristinsdottir AM, Stefansson H, Masson G, Magnusson OT, Halldorsson BV, Kong A, Rafnar T, Thorsteinsdottir U, Vogel U, Kumar R, Nagore E, Mayordomo JI, Gudbjartsson DF, Olafsson JH, Stefansson K
Nat Commun 2015 Apr 9;6:6825. doi: 10.1038/ncomms7825. PMID: 25855136Free PMC Article
Strange RC, Spiteri MA, Ramachandran S, Fryer AA
Mutat Res 2001 Oct 1;482(1-2):21-6. doi: 10.1016/s0027-5107(01)00206-8. PMID: 11535245

Diagnosis

Patil P, Pencheva BB, Patil VM, Fangusaro J
Neurotherapeutics 2022 Oct;19(6):1752-1771. Epub 2022 Sep 2 doi: 10.1007/s13311-022-01277-w. PMID: 36056180Free PMC Article
Josiah AJ, Twilley D, Pillai SK, Ray SS, Lall N
Molecules 2021 Apr 1;26(7) doi: 10.3390/molecules26071979. PMID: 33915735Free PMC Article
Vanderbeck K, Orr CE, Parvinnejad N, Wang T, Bradshaw S, Wang A, Asai Y
J Cutan Pathol 2021 Jul;48(7):877-883. Epub 2021 Feb 18 doi: 10.1111/cup.13975. PMID: 33543489
Kasumagic-Halilovic E, Hasic M, Ovcina-Kurtovic N
Med Arch 2019 Dec;73(6):394-398. doi: 10.5455/medarh.2019.73.394-398. PMID: 32082007Free PMC Article
Totir M, Alexandrescu C, Pirvulescu R, Gradinaru S, Costache M
J Med Life 2014;7 Spec No. 4(Spec Iss 4):18-22. PMID: 27057245Free PMC Article

Therapy

Scola L, Bongiorno MR, Forte GI, Aiello A, Accardi G, Scrimali C, Spina R, Lio D, Candore G
Genes (Basel) 2022 Jul 13;13(7) doi: 10.3390/genes13071235. PMID: 35886018Free PMC Article
Josiah AJ, Twilley D, Pillai SK, Ray SS, Lall N
Molecules 2021 Apr 1;26(7) doi: 10.3390/molecules26071979. PMID: 33915735Free PMC Article
Seviiri M, Law MH, Ong JS, Gharahkhani P, Nyholt DR, Olsen CM, Whiteman DC, MacGregor S
J Invest Dermatol 2021 Feb;141(2):325-333.e6. Epub 2020 Jun 29 doi: 10.1016/j.jid.2020.06.017. PMID: 32615124
van der Poort EKJ, Gunn DA, Beekman M, Griffiths CEM, Slagboom PE, van Heemst D, Noordam R
J Eur Acad Dermatol Venereol 2020 Jan;34(1):97-100. Epub 2019 Sep 5 doi: 10.1111/jdv.15880. PMID: 31419349
Bonilla X, Parmentier L, King B, Bezrukov F, Kaya G, Zoete V, Seplyarskiy VB, Sharpe HJ, McKee T, Letourneau A, Ribaux PG, Popadin K, Basset-Seguin N, Ben Chaabene R, Santoni FA, Andrianova MA, Guipponi M, Garieri M, Verdan C, Grosdemange K, Sumara O, Eilers M, Aifantis I, Michielin O, de Sauvage FJ, Antonarakis SE, Nikolaev SI
Nat Genet 2016 Apr;48(4):398-406. Epub 2016 Mar 7 doi: 10.1038/ng.3525. PMID: 26950094

Prognosis

Patil P, Pencheva BB, Patil VM, Fangusaro J
Neurotherapeutics 2022 Oct;19(6):1752-1771. Epub 2022 Sep 2 doi: 10.1007/s13311-022-01277-w. PMID: 36056180Free PMC Article
Manganelli M, Guida S, Ferretta A, Pellacani G, Porcelli L, Azzariti A, Guida G
Genes (Basel) 2021 Jul 19;12(7) doi: 10.3390/genes12071093. PMID: 34356109Free PMC Article
Josiah AJ, Twilley D, Pillai SK, Ray SS, Lall N
Molecules 2021 Apr 1;26(7) doi: 10.3390/molecules26071979. PMID: 33915735Free PMC Article
Seviiri M, Law MH, Ong JS, Gharahkhani P, Nyholt DR, Olsen CM, Whiteman DC, MacGregor S
J Invest Dermatol 2021 Feb;141(2):325-333.e6. Epub 2020 Jun 29 doi: 10.1016/j.jid.2020.06.017. PMID: 32615124
Roberts MR, Asgari MM, Toland AE
Br J Dermatol 2019 Dec;181(6):1146-1155. Epub 2019 Jul 7 doi: 10.1111/bjd.17917. PMID: 30908599Free PMC Article

Clinical prediction guides

Patil P, Pencheva BB, Patil VM, Fangusaro J
Neurotherapeutics 2022 Oct;19(6):1752-1771. Epub 2022 Sep 2 doi: 10.1007/s13311-022-01277-w. PMID: 36056180Free PMC Article
Seviiri M, Law MH, Ong JS, Gharahkhani P, Nyholt DR, Olsen CM, Whiteman DC, MacGregor S
J Invest Dermatol 2021 Feb;141(2):325-333.e6. Epub 2020 Jun 29 doi: 10.1016/j.jid.2020.06.017. PMID: 32615124
van der Poort EKJ, Gunn DA, Beekman M, Griffiths CEM, Slagboom PE, van Heemst D, Noordam R
J Eur Acad Dermatol Venereol 2020 Jan;34(1):97-100. Epub 2019 Sep 5 doi: 10.1111/jdv.15880. PMID: 31419349
Roberts MR, Asgari MM, Toland AE
Br J Dermatol 2019 Dec;181(6):1146-1155. Epub 2019 Jul 7 doi: 10.1111/bjd.17917. PMID: 30908599Free PMC Article
Bonilla X, Parmentier L, King B, Bezrukov F, Kaya G, Zoete V, Seplyarskiy VB, Sharpe HJ, McKee T, Letourneau A, Ribaux PG, Popadin K, Basset-Seguin N, Ben Chaabene R, Santoni FA, Andrianova MA, Guipponi M, Garieri M, Verdan C, Grosdemange K, Sumara O, Eilers M, Aifantis I, Michielin O, de Sauvage FJ, Antonarakis SE, Nikolaev SI
Nat Genet 2016 Apr;48(4):398-406. Epub 2016 Mar 7 doi: 10.1038/ng.3525. PMID: 26950094

Supplemental Content

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    Clinical resources

    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2023
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Basal Cell Skin Cancer, 2023

    Consumer resources

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