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Vasa previa

MedGen UID:
75716
•Concept ID:
C0269852
•
Anatomical Abnormality; Anatomical Abnormality
Synonyms: Praevia, Vasa; Praevias, Vasa; Previa, Vasa; Previas, Vasa; Vasa Praevia; Vasa Praevias; Vasa Previa; Vasa Previas
SNOMED CT: Vasa previa (79668009)
 
HPO: HP:0033991

Definition

Vasa previa occurs when the membranes that contain the umbilical cord traverse the membranes overlying the internal os of the cervix. There is a high risk of fetal mortality if not identified perinatally. [from HPO]

Professional guidelines

PubMed

Individualized management of vasa previa and neonatal outcomes.
Saji S, Hasegawa J, Oyelese Y, Furuya N, Homma C, Nishimura Y, Nakamura M, Suzuki N
J Obstet Gynaecol Res 2023 Nov;49(11):2680-2685. Epub 2023 Aug 24 doi: 10.1111/jog.15775. PMID: 37621145
Guideline No. 439: Diagnosis and Management of Vasa Previa.
Jain V, Gagnon R
J Obstet Gynaecol Can 2023 Jul;45(7):506-518. Epub 2023 May 18 doi: 10.1016/j.jogc.2023.05.009. PMID: 37209787
Vasa previa: prenatal diagnosis and management.
Melcer Y, Maymon R, Jauniaux E
Curr Opin Obstet Gynecol 2018 Dec;30(6):385-391. doi: 10.1097/GCO.0000000000000478. PMID: 30102606

Recent clinical studies

Etiology

Vasa Previa.
Oyelese Y, Javinani A, Shamshirsaz AA
Obstet Gynecol 2023 Sep 1;142(3):503-518. Epub 2023 Aug 3 doi: 10.1097/AOG.0000000000005287. PMID: 37590981Free PMC Article
Guideline No. 439: Diagnosis and Management of Vasa Previa.
Jain V, Gagnon R
J Obstet Gynaecol Can 2023 Jul;45(7):506-518. Epub 2023 May 18 doi: 10.1016/j.jogc.2023.05.009. PMID: 37209787
Umbilical Cord Abnormalities and Stillbirth.
Hammad IA, Blue NR, Allshouse AA, Silver RM, Gibbins KJ, Page JM, Goldenberg RL, Reddy UM, Saade GR, Dudley DJ, Thorsten VR, Conway DL, Pinar H, Pysher TJ; NICHD Stillbirth Collaborative Research Network Group
Obstet Gynecol 2020 Mar;135(3):644-652. doi: 10.1097/AOG.0000000000003676. PMID: 32028503Free PMC Article
Abnormal Placentation: Placenta Previa, Vasa Previa, and Placenta Accreta.
Silver RM
Obstet Gynecol 2015 Sep;126(3):654-668. doi: 10.1097/AOG.0000000000001005. PMID: 26244528
Placenta previa, placenta accreta, and vasa previa.
Oyelese Y, Smulian JC
Obstet Gynecol 2006 Apr;107(4):927-41. doi: 10.1097/01.AOG.0000207559.15715.98. PMID: 16582134

Diagnosis

Vasa Previa.
Oyelese Y, Javinani A, Shamshirsaz AA
Obstet Gynecol 2023 Sep 1;142(3):503-518. Epub 2023 Aug 3 doi: 10.1097/AOG.0000000000005287. PMID: 37590981Free PMC Article
Guideline No. 439: Diagnosis and Management of Vasa Previa.
Jain V, Gagnon R
J Obstet Gynaecol Can 2023 Jul;45(7):506-518. Epub 2023 May 18 doi: 10.1016/j.jogc.2023.05.009. PMID: 37209787
Placental Implantation Disorders.
Jauniaux E, Moffett A, Burton GJ
Obstet Gynecol Clin North Am 2020 Mar;47(1):117-132. Epub 2019 Dec 18 doi: 10.1016/j.ogc.2019.10.002. PMID: 32008663
Abnormal Placentation: Placenta Previa, Vasa Previa, and Placenta Accreta.
Silver RM
Obstet Gynecol 2015 Sep;126(3):654-668. doi: 10.1097/AOG.0000000000001005. PMID: 26244528
Placenta previa, placenta accreta, and vasa previa.
Oyelese Y, Smulian JC
Obstet Gynecol 2006 Apr;107(4):927-41. doi: 10.1097/01.AOG.0000207559.15715.98. PMID: 16582134

Therapy

Vasa Previa.
Oyelese Y, Javinani A, Shamshirsaz AA
Obstet Gynecol 2023 Sep 1;142(3):503-518. Epub 2023 Aug 3 doi: 10.1097/AOG.0000000000005287. PMID: 37590981Free PMC Article
Ultrasound screening and management of vasa previa in Japan.
Furuya N, Sasaki T, Homma C, Hasegawa J, Suzuki N
J Obstet Gynaecol Res 2020 Jul;46(7):1084-1089. Epub 2020 Apr 12 doi: 10.1111/jog.14254. PMID: 32281219
Vasa previa: prenatal diagnosis and management.
Melcer Y, Maymon R, Jauniaux E
Curr Opin Obstet Gynecol 2018 Dec;30(6):385-391. doi: 10.1097/GCO.0000000000000478. PMID: 30102606
Vasa previa: diagnosis and management.
Swank ML, Garite TJ, Maurel K, Das A, Perlow JH, Combs CA, Fishman S, Vanderhoeven J, Nageotte M, Bush M, Lewis D; Obstetrix Collaborative Research Network
Am J Obstet Gynecol 2016 Aug;215(2):223.e1-6. Epub 2016 Mar 2 doi: 10.1016/j.ajog.2016.02.044. PMID: 26944186
Placenta previa, placenta accreta, and vasa previa.
Oyelese Y, Smulian JC
Obstet Gynecol 2006 Apr;107(4):927-41. doi: 10.1097/01.AOG.0000207559.15715.98. PMID: 16582134

Prognosis

Vasa previa: when antenatal diagnosis can change fetal prognosis.
Sutera M, Garofalo A, Pilloni E, Parisi S, Alemanno MG, Menato G, Sciarrone A, Viora E
J Perinat Med 2021 Sep 27;49(7):915-922. Epub 2021 May 4 doi: 10.1515/jpm-2020-0559. PMID: 33939903
Vasa previa: Perinatal outcomes in singleton and multiple pregnancies.
Liu N, Hu Q, Liao H, Wang X, Yu H
Biosci Trends 2021 May 11;15(2):118-125. Epub 2021 Mar 21 doi: 10.5582/bst.2021.01052. PMID: 33746156
Vasa Previa Diagnosis, Clinical Practice, and Outcomes in Australia.
Sullivan EA, Javid N, Duncombe G, Li Z, Safi N, Cincotta R, Homer CSE, Halliday L, Oyelese Y
Obstet Gynecol 2017 Sep;130(3):591-598. doi: 10.1097/AOG.0000000000002198. PMID: 28796681
Vasa previa is not infrequent.
Hasegawa J, Nakamura M, Ichizuka K, Matsuoka R, Sekizawa A, Okai T
J Matern Fetal Neonatal Med 2012 Dec;25(12):2795-6. Epub 2012 Aug 20 doi: 10.3109/14767058.2012.712570. PMID: 22839499
Placenta previa, placenta accreta, and vasa previa.
Oyelese Y, Smulian JC
Obstet Gynecol 2006 Apr;107(4):927-41. doi: 10.1097/01.AOG.0000207559.15715.98. PMID: 16582134

Clinical prediction guides

Prenatal diagnosis and postnatal outcome of Type-III vasa previa: systematic review of literature.
Pozzoni M, Sammaria C, Villanacci R, Borgese C, Ghisleri F, Farina A, Candiani M, Cavoretto PI
Ultrasound Obstet Gynecol 2024 Jan;63(1):24-33. doi: 10.1002/uog.26315. PMID: 37470694
Clinical characteristics of a novel "Type 3" vasa previa: case series at a single center.
Kamijo K, Miyamoto T, Ando H, Tanaka Y, Kikuchi N, Shinagawa M, Yamada S, Asaka R, Fuseya C, Ohira S, Shiozawa T
J Matern Fetal Neonatal Med 2022 Dec;35(25):7730-7736. Epub 2021 Aug 9 doi: 10.1080/14767058.2021.1960975. PMID: 34372741
Vasa previa: when antenatal diagnosis can change fetal prognosis.
Sutera M, Garofalo A, Pilloni E, Parisi S, Alemanno MG, Menato G, Sciarrone A, Viora E
J Perinat Med 2021 Sep 27;49(7):915-922. Epub 2021 May 4 doi: 10.1515/jpm-2020-0559. PMID: 33939903
Variations in reported outcomes in studies on vasa previa: a systematic review.
Villani LA, Pavalagantharajah S, D'Souza R
Am J Obstet Gynecol MFM 2020 Aug;2(3):100116. Epub 2020 Apr 16 doi: 10.1016/j.ajogmf.2020.100116. PMID: 33345867
Vasa previa: clinical presentations, outcomes, and implications for management.
Bronsteen R, Whitten A, Balasubramanian M, Lee W, Lorenz R, Redman M, Goncalves L, Seubert D, Bauer S, Comstock C
Obstet Gynecol 2013 Aug;122(2 Pt 1):352-357. doi: 10.1097/AOG.0b013e31829cac58. PMID: 23969805

Recent systematic reviews

Incidence of vasa praevia: a systematic review and meta-analysis.
Zhang W, Giacchino T, Chanyarungrojn PA, Ionescu O, Akolekar R
BMJ Open 2023 Sep 20;13(9):e075245. doi: 10.1136/bmjopen-2023-075245. PMID: 37730391Free PMC Article
Vasa previa and associated risk factors: a systematic review and meta-analysis.
Pavalagantharajah S, Villani LA, D'Souza R
Am J Obstet Gynecol MFM 2020 Aug;2(3):100117. Epub 2020 Apr 15 doi: 10.1016/j.ajogmf.2020.100117. PMID: 33345868
Vasa previa: prenatal diagnosis and management.
Melcer Y, Maymon R, Jauniaux E
Curr Opin Obstet Gynecol 2018 Dec;30(6):385-391. doi: 10.1097/GCO.0000000000000478. PMID: 30102606
Incidence of and risk indicators for vasa praevia: a systematic review.
Ruiter L, Kok N, Limpens J, Derks JB, de Graaf IM, Mol B, Pajkrt E
BJOG 2016 Jul;123(8):1278-87. Epub 2015 Dec 23 doi: 10.1111/1471-0528.13829. PMID: 26694639
Systematic review of accuracy of ultrasound in the diagnosis of vasa previa.
Ruiter L, Kok N, Limpens J, Derks JB, de Graaf IM, Mol BW, Pajkrt E
Ultrasound Obstet Gynecol 2015 May;45(5):516-22. Epub 2015 Apr 13 doi: 10.1002/uog.14752. PMID: 25491755

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