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Calcification of muscles

MedGen UID:
755917
•Concept ID:
C2960760
•
Disease or Syndrome; Finding
Synonyms: Calcification of muscle; Skeletal muscle calcinosis
SNOMED CT: Calcification of muscle (446993003)
 
HPO: HP:0100249

Definition

Deposition of calcium salts in muscle tissue. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCalcification of muscles

Professional guidelines

PubMed

Juvenile Dermatomyositis: Advances in Pathogenesis, Assessment, and Management.
Leung AKC, Lam JM, Alobaida S, Leong KF, Wong AHC
Curr Pediatr Rev 2021;17(4):273-287. doi: 10.2174/1573396317666210426105045. PMID: 33902423
Rotator cuff calcific tendinopathy: from diagnosis to treatment.
Chianca V, Albano D, Messina C, Midiri F, Mauri G, Aliprandi A, Catapano M, Pescatori LC, Monaco CG, Gitto S, Pisani Mainini A, Corazza A, Rapisarda S, Pozzi G, Barile A, Masciocchi C, Sconfienza LM
Acta Biomed 2018 Jan 19;89(1-S):186-196. doi: 10.23750/abm.v89i1-S.7022. PMID: 29350647Free PMC Article
Evaluation and nonsurgical management of rotator cuff calcific tendinopathy.
Greis AC, Derrington SM, McAuliffe M
Orthop Clin North Am 2015 Apr;46(2):293-302. Epub 2015 Jan 27 doi: 10.1016/j.ocl.2014.11.011. PMID: 25771323

Recent clinical studies

Etiology

Orphan Nuclear Receptor NR4A3 Promotes Vascular Calcification via Histone Lactylation.
Ma W, Jia K, Cheng H, Xu H, Li Z, Zhang H, Xie H, Sun H, Yi L, Chen Z, Duan S, Sano M, Fukuda K, Lu L, Gao F, Zhang R, Yan X
Circ Res 2024 May 24;134(11):1427-1447. Epub 2024 Apr 17 doi: 10.1161/CIRCRESAHA.123.323699. PMID: 38629274
Vascular Calcification-New Insights Into Its Mechanism.
Lee SJ, Lee IK, Jeon JH
Int J Mol Sci 2020 Apr 13;21(8) doi: 10.3390/ijms21082685. PMID: 32294899Free PMC Article
Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness.
Durham AL, Speer MY, Scatena M, Giachelli CM, Shanahan CM
Cardiovasc Res 2018 Mar 15;114(4):590-600. doi: 10.1093/cvr/cvy010. PMID: 29514202Free PMC Article
Coronary Artery Calcification: From Mechanism to Molecular Imaging.
Nakahara T, Dweck MR, Narula N, Pisapia D, Narula J, Strauss HW
JACC Cardiovasc Imaging 2017 May;10(5):582-593. doi: 10.1016/j.jcmg.2017.03.005. PMID: 28473100
Vascular calcification: Mechanisms of vascular smooth muscle cell calcification.
Leopold JA
Trends Cardiovasc Med 2015 May;25(4):267-74. Epub 2014 Oct 30 doi: 10.1016/j.tcm.2014.10.021. PMID: 25435520Free PMC Article

Diagnosis

Vascular Calcification-New Insights Into Its Mechanism.
Lee SJ, Lee IK, Jeon JH
Int J Mol Sci 2020 Apr 13;21(8) doi: 10.3390/ijms21082685. PMID: 32294899Free PMC Article
Rotator cuff calcific tendinopathy: from diagnosis to treatment.
Chianca V, Albano D, Messina C, Midiri F, Mauri G, Aliprandi A, Catapano M, Pescatori LC, Monaco CG, Gitto S, Pisani Mainini A, Corazza A, Rapisarda S, Pozzi G, Barile A, Masciocchi C, Sconfienza LM
Acta Biomed 2018 Jan 19;89(1-S):186-196. doi: 10.23750/abm.v89i1-S.7022. PMID: 29350647Free PMC Article
Coronary Artery Calcification: From Mechanism to Molecular Imaging.
Nakahara T, Dweck MR, Narula N, Pisapia D, Narula J, Strauss HW
JACC Cardiovasc Imaging 2017 May;10(5):582-593. doi: 10.1016/j.jcmg.2017.03.005. PMID: 28473100
Calcific tendinitis of the rotator cuff: state of the art in diagnosis and treatment.
Merolla G, Singh S, Paladini P, Porcellini G
J Orthop Traumatol 2016 Mar;17(1):7-14. Epub 2015 Jul 12 doi: 10.1007/s10195-015-0367-6. PMID: 26163832Free PMC Article
Evaluation and nonsurgical management of rotator cuff calcific tendinopathy.
Greis AC, Derrington SM, McAuliffe M
Orthop Clin North Am 2015 Apr;46(2):293-302. Epub 2015 Jan 27 doi: 10.1016/j.ocl.2014.11.011. PMID: 25771323

Therapy

Intravenous Immunoglobulin in Idiopathic Inflammatory Myopathies: a Practical Guide for Clinical Use.
Gandiga PC, Ghetie D, Anderson E, Aggrawal R
Curr Rheumatol Rep 2023 Aug;25(8):152-168. Epub 2023 Jun 1 doi: 10.1007/s11926-023-01105-w. PMID: 37261663
The emerging role of magnesium in CKD.
Sakaguchi Y
Clin Exp Nephrol 2022 May;26(5):379-384. Epub 2022 Jan 25 doi: 10.1007/s10157-022-02182-4. PMID: 35076791Free PMC Article
Electrotherapy modalities for rotator cuff disease.
Page MJ, Green S, Mrocki MA, Surace SJ, Deitch J, McBain B, Lyttle N, Buchbinder R
Cochrane Database Syst Rev 2016 Jun 10;2016(6):CD012225. doi: 10.1002/14651858.CD012225. PMID: 27283591Free PMC Article
Evaluation and nonsurgical management of rotator cuff calcific tendinopathy.
Greis AC, Derrington SM, McAuliffe M
Orthop Clin North Am 2015 Apr;46(2):293-302. Epub 2015 Jan 27 doi: 10.1016/j.ocl.2014.11.011. PMID: 25771323
A systematic review of shockwave therapies in soft tissue conditions: focusing on the evidence.
Speed C
Br J Sports Med 2014 Nov;48(21):1538-42. Epub 2013 Aug 5 doi: 10.1136/bjsports-2012-091961. PMID: 23918444

Prognosis

Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes.
Theofilatos K, Stojkovic S, Hasman M, van der Laan SW, Baig F, Barallobre-Barreiro J, Schmidt LE, Yin S, Yin X, Burnap S, Singh B, Popham J, Harkot O, Kampf S, Nackenhorst MC, Strassl A, Loewe C, Demyanets S, Neumayer C, Bilban M, Hengstenberg C, Huber K, Pasterkamp G, Wojta J, Mayr M
Circ Res 2023 Sep 15;133(7):542-558. Epub 2023 Aug 30 doi: 10.1161/CIRCRESAHA.123.322590. PMID: 37646165Free PMC Article
ALKBH1-demethylated DNA N6-methyladenine modification triggers vascular calcification via osteogenic reprogramming in chronic kidney disease.
Ouyang L, Su X, Li W, Tang L, Zhang M, Zhu Y, Xie C, Zhang P, Chen J, Huang H
J Clin Invest 2021 Jul 15;131(14) doi: 10.1172/JCI146985. PMID: 34003800Free PMC Article
Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches.
Düsing P, Zietzer A, Goody PR, Hosen MR, Kurts C, Nickenig G, Jansen F
J Mol Med (Berl) 2021 Mar;99(3):335-348. Epub 2021 Jan 22 doi: 10.1007/s00109-021-02037-7. PMID: 33481059Free PMC Article
Metabolism of vascular smooth muscle cells in vascular diseases.
Shi J, Yang Y, Cheng A, Xu G, He F
Am J Physiol Heart Circ Physiol 2020 Sep 1;319(3):H613-H631. Epub 2020 Aug 7 doi: 10.1152/ajpheart.00220.2020. PMID: 32762559
Coronary Artery Calcification: From Mechanism to Molecular Imaging.
Nakahara T, Dweck MR, Narula N, Pisapia D, Narula J, Strauss HW
JACC Cardiovasc Imaging 2017 May;10(5):582-593. doi: 10.1016/j.jcmg.2017.03.005. PMID: 28473100

Clinical prediction guides

Orphan Nuclear Receptor NR4A3 Promotes Vascular Calcification via Histone Lactylation.
Ma W, Jia K, Cheng H, Xu H, Li Z, Zhang H, Xie H, Sun H, Yi L, Chen Z, Duan S, Sano M, Fukuda K, Lu L, Gao F, Zhang R, Yan X
Circ Res 2024 May 24;134(11):1427-1447. Epub 2024 Apr 17 doi: 10.1161/CIRCRESAHA.123.323699. PMID: 38629274
Carbonylation of Runx2 at K176 by 4-Hydroxynonenal Accelerates Vascular Calcification.
Zhai X, Cao S, Wang J, Qiao B, Liu X, Hua R, Zhao M, Sun S, Han Y, Wu S, Pang J, Yuan Q, Wang B, Xu F, Wei S, Chen Y
Circulation 2024 May 28;149(22):1752-1769. Epub 2024 Feb 13 doi: 10.1161/CIRCULATIONAHA.123.065830. PMID: 38348663
Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes.
Theofilatos K, Stojkovic S, Hasman M, van der Laan SW, Baig F, Barallobre-Barreiro J, Schmidt LE, Yin S, Yin X, Burnap S, Singh B, Popham J, Harkot O, Kampf S, Nackenhorst MC, Strassl A, Loewe C, Demyanets S, Neumayer C, Bilban M, Hengstenberg C, Huber K, Pasterkamp G, Wojta J, Mayr M
Circ Res 2023 Sep 15;133(7):542-558. Epub 2023 Aug 30 doi: 10.1161/CIRCRESAHA.123.322590. PMID: 37646165Free PMC Article
ERK1/2 inhibition reduces vascular calcification by activating miR-126-3p-DKK1/LRP6 pathway.
Zeng P, Yang J, Liu L, Yang X, Yao Z, Ma C, Zhu H, Su J, Zhao Q, Feng K, Yang S, Zhu Y, Li X, Wang W, Duan Y, Han J, Chen Y
Theranostics 2021;11(3):1129-1146. Epub 2021 Jan 1 doi: 10.7150/thno.49771. PMID: 33391525Free PMC Article
Coronary Artery Calcification: From Mechanism to Molecular Imaging.
Nakahara T, Dweck MR, Narula N, Pisapia D, Narula J, Strauss HW
JACC Cardiovasc Imaging 2017 May;10(5):582-593. doi: 10.1016/j.jcmg.2017.03.005. PMID: 28473100

Recent systematic reviews

Effect of extracorporeal shockwave therapy for rotator cuff tendinopathy: a systematic review and meta-analysis.
Xue X, Song Q, Yang X, Kuati A, Fu H, Liu Y, Cui G
BMC Musculoskelet Disord 2024 May 4;25(1):357. doi: 10.1186/s12891-024-07445-7. PMID: 38704572Free PMC Article
Chronic calcific tendonitis of the rotator cuff: a systematic review and meta-analysis of randomized controlled trials comparing operative and nonoperative interventions.
Angileri HS, Gohal C, Comeau-Gauthier M, Owen MM, Shanmugaraj A, Terry MA, Tjong VK, Khan M
J Shoulder Elbow Surg 2023 Aug;32(8):1746-1760. Epub 2023 Apr 18 doi: 10.1016/j.jse.2023.03.017. PMID: 37080421
Shock wave therapy for rotator cuff disease with or without calcification.
Surace SJ, Deitch J, Johnston RV, Buchbinder R
Cochrane Database Syst Rev 2020 Mar 4;3(3):CD008962. doi: 10.1002/14651858.CD008962.pub2. PMID: 32128761Free PMC Article
Electrotherapy modalities for rotator cuff disease.
Page MJ, Green S, Mrocki MA, Surace SJ, Deitch J, McBain B, Lyttle N, Buchbinder R
Cochrane Database Syst Rev 2016 Jun 10;2016(6):CD012225. doi: 10.1002/14651858.CD012225. PMID: 27283591Free PMC Article
A systematic review of shockwave therapies in soft tissue conditions: focusing on the evidence.
Speed C
Br J Sports Med 2014 Nov;48(21):1538-42. Epub 2013 Aug 5 doi: 10.1136/bjsports-2012-091961. PMID: 23918444

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