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Healthcare-Associated Pneumonia

MedGen UID:
730707
Concept ID:
C1443237
Disease or Syndrome
Synonyms: Healthcare Associated Pneumonia; Healthcare-Associated Pneumonias; Nosocomial Pneumonia; Nosocomial Pneumonias; Pneumonia, Healthcare-Associated; Pneumonia, Nosocomial

Definition

Infection of the lung often accompanied by inflammation that is acquired through an interaction within a healthcare institution often through a therapeutic experience (e.g., use of catheters or ventilators). [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHealthcare-Associated Pneumonia

Professional guidelines

PubMed

Mylotte JM
J Am Med Dir Assoc 2020 Mar;21(3):315-321. Epub 2020 Feb 13 doi: 10.1016/j.jamda.2020.01.012. PMID: 32061505Free PMC Article
Parente DM, Cunha CB, Mylonakis E, Timbrook TT
Clin Infect Dis 2018 Jun 18;67(1):1-7. doi: 10.1093/cid/ciy024. PMID: 29340593
American Thoracic Society; Infectious Diseases Society of America
Am J Respir Crit Care Med 2005 Feb 15;171(4):388-416. doi: 10.1164/rccm.200405-644ST. PMID: 15699079

Recent clinical studies

Etiology

Liu JY, Dickter JK
Gastrointest Endosc Clin N Am 2020 Oct;30(4):637-652. Epub 2020 Jul 30 doi: 10.1016/j.giec.2020.06.001. PMID: 32891222
Zaragoza R, Vidal-Cortés P, Aguilar G, Borges M, Diaz E, Ferrer R, Maseda E, Nieto M, Nuvials FX, Ramirez P, Rodriguez A, Soriano C, Veganzones J, Martín-Loeches I
Crit Care 2020 Jun 29;24(1):383. doi: 10.1186/s13054-020-03091-2. PMID: 32600375Free PMC Article
Lanks CW, Musani AI, Hsia DW
Med Clin North Am 2019 May;103(3):487-501. Epub 2019 Mar 7 doi: 10.1016/j.mcna.2018.12.008. PMID: 30955516
Martin-Loeches I, Rodriguez AH, Torres A
Curr Opin Crit Care 2018 Oct;24(5):347-352. doi: 10.1097/MCC.0000000000000535. PMID: 30063491
American Thoracic Society; Infectious Diseases Society of America
Am J Respir Crit Care Med 2005 Feb 15;171(4):388-416. doi: 10.1164/rccm.200405-644ST. PMID: 15699079

Diagnosis

Modi AR, Kovacs CS
Cleve Clin J Med 2020 Oct 1;87(10):633-639. doi: 10.3949/ccjm.87a.19117. PMID: 33004324
Zaragoza R, Vidal-Cortés P, Aguilar G, Borges M, Diaz E, Ferrer R, Maseda E, Nieto M, Nuvials FX, Ramirez P, Rodriguez A, Soriano C, Veganzones J, Martín-Loeches I
Crit Care 2020 Jun 29;24(1):383. doi: 10.1186/s13054-020-03091-2. PMID: 32600375Free PMC Article
Lanks CW, Musani AI, Hsia DW
Med Clin North Am 2019 May;103(3):487-501. Epub 2019 Mar 7 doi: 10.1016/j.mcna.2018.12.008. PMID: 30955516
Leone M, Bouadma L, Bouhemad B, Brissaud O, Dauger S, Gibot S, Hraiech S, Jung B, Kipnis E, Launey Y, Luyt CE, Margetis D, Michel F, Mokart D, Montravers P, Monsel A, Nseir S, Pugin J, Roquilly A, Velly L, Zahar JR, Bruyère R, Chanques G
Anaesth Crit Care Pain Med 2018 Feb;37(1):83-98. Epub 2017 Nov 15 doi: 10.1016/j.accpm.2017.11.006. PMID: 29155054
American Thoracic Society; Infectious Diseases Society of America
Am J Respir Crit Care Med 2005 Feb 15;171(4):388-416. doi: 10.1164/rccm.200405-644ST. PMID: 15699079

Therapy

Klompas M, Branson R, Cawcutt K, Crist M, Eichenwald EC, Greene LR, Lee G, Maragakis LL, Powell K, Priebe GP, Speck K, Yokoe DS, Berenholtz SM
Infect Control Hosp Epidemiol 2022 Jun;43(6):687-713. Epub 2022 May 20 doi: 10.1017/ice.2022.88. PMID: 35589091Free PMC Article
Zaragoza R, Vidal-Cortés P, Aguilar G, Borges M, Diaz E, Ferrer R, Maseda E, Nieto M, Nuvials FX, Ramirez P, Rodriguez A, Soriano C, Veganzones J, Martín-Loeches I
Crit Care 2020 Jun 29;24(1):383. doi: 10.1186/s13054-020-03091-2. PMID: 32600375Free PMC Article
Lanks CW, Musani AI, Hsia DW
Med Clin North Am 2019 May;103(3):487-501. Epub 2019 Mar 7 doi: 10.1016/j.mcna.2018.12.008. PMID: 30955516
Martin-Loeches I, Rodriguez AH, Torres A
Curr Opin Crit Care 2018 Oct;24(5):347-352. doi: 10.1097/MCC.0000000000000535. PMID: 30063491
American Thoracic Society; Infectious Diseases Society of America
Am J Respir Crit Care Med 2005 Feb 15;171(4):388-416. doi: 10.1164/rccm.200405-644ST. PMID: 15699079

Prognosis

Wong Fok Lung T, Charytonowicz D, Beaumont KG, Shah SS, Sridhar SH, Gorrie CL, Mu A, Hofstaedter CE, Varisco D, McConville TH, Drikic M, Fowler B, Urso A, Shi W, Fucich D, Annavajhala MK, Khan IN, Oussenko I, Francoeur N, Smith ML, Stockwell BR, Lewis IA, Hachani A, Upadhyay Baskota S, Uhlemann AC, Ahn D, Ernst RK, Howden BP, Sebra R, Prince A
Cell Metab 2022 May 3;34(5):761-774.e9. Epub 2022 Apr 11 doi: 10.1016/j.cmet.2022.03.009. PMID: 35413274Free PMC Article
Teramoto S
Respir Investig 2022 Jan;60(1):45-55. Epub 2021 Nov 12 doi: 10.1016/j.resinv.2021.09.012. PMID: 34782300
Liu JY, Dickter JK
Gastrointest Endosc Clin N Am 2020 Oct;30(4):637-652. Epub 2020 Jul 30 doi: 10.1016/j.giec.2020.06.001. PMID: 32891222
Zhanel GG, Golden AR, Zelenitsky S, Wiebe K, Lawrence CK, Adam HJ, Idowu T, Domalaon R, Schweizer F, Zhanel MA, Lagacé-Wiens PRS, Walkty AJ, Noreddin A, Lynch Iii JP, Karlowsky JA
Drugs 2019 Feb;79(3):271-289. doi: 10.1007/s40265-019-1055-2. PMID: 30712199
Martin-Loeches I, Rodriguez AH, Torres A
Curr Opin Crit Care 2018 Oct;24(5):347-352. doi: 10.1097/MCC.0000000000000535. PMID: 30063491

Clinical prediction guides

Barbier F, Dupuis C, Buetti N, Schwebel C, Azoulay É, Argaud L, Cohen Y, Hong Tuan Ha V, Gainnier M, Siami S, Forel JM, Adrie C, de Montmollin É, Reignier J, Ruckly S, Zahar JR, Timsit JF; OutcomeRéa Study Group
Crit Care 2024 Jan 3;28(1):10. doi: 10.1186/s13054-023-04792-0. PMID: 38172969Free PMC Article
Wong Fok Lung T, Charytonowicz D, Beaumont KG, Shah SS, Sridhar SH, Gorrie CL, Mu A, Hofstaedter CE, Varisco D, McConville TH, Drikic M, Fowler B, Urso A, Shi W, Fucich D, Annavajhala MK, Khan IN, Oussenko I, Francoeur N, Smith ML, Stockwell BR, Lewis IA, Hachani A, Upadhyay Baskota S, Uhlemann AC, Ahn D, Ernst RK, Howden BP, Sebra R, Prince A
Cell Metab 2022 May 3;34(5):761-774.e9. Epub 2022 Apr 11 doi: 10.1016/j.cmet.2022.03.009. PMID: 35413274Free PMC Article
Wunderink RG, Matsunaga Y, Ariyasu M, Clevenbergh P, Echols R, Kaye KS, Kollef M, Menon A, Pogue JM, Shorr AF, Timsit JF, Zeitlinger M, Nagata TD
Lancet Infect Dis 2021 Feb;21(2):213-225. Epub 2020 Oct 12 doi: 10.1016/S1473-3099(20)30731-3. PMID: 33058798
Zhanel GG, Golden AR, Zelenitsky S, Wiebe K, Lawrence CK, Adam HJ, Idowu T, Domalaon R, Schweizer F, Zhanel MA, Lagacé-Wiens PRS, Walkty AJ, Noreddin A, Lynch Iii JP, Karlowsky JA
Drugs 2019 Feb;79(3):271-289. doi: 10.1007/s40265-019-1055-2. PMID: 30712199
Martin-Loeches I, Rodriguez AH, Torres A
Curr Opin Crit Care 2018 Oct;24(5):347-352. doi: 10.1097/MCC.0000000000000535. PMID: 30063491

Recent systematic reviews

Noguchi S, Katsurada M, Yatera K, Nakagawa N, Xu D, Fukuda Y, Shindo Y, Senda K, Tsukada H, Miki M, Mukae H
Sci Rep 2024 Jun 5;14(1):12964. doi: 10.1038/s41598-024-63618-3. PMID: 38839837Free PMC Article
Lukasewicz Ferreira SA, Hubner Dalmora C, Anziliero F, de Souza Kuchenbecker R, Klarmann Ziegelmann P
J Hosp Infect 2022 Jan;119:64-76. Epub 2021 Oct 16 doi: 10.1016/j.jhin.2021.09.024. PMID: 34666117
Mitchell BG, Russo PL, Cheng AC, Stewardson AJ, Rosebrock H, Curtis SJ, Robinson S, Kiernan M
Infect Dis Health 2019 Nov;24(4):229-239. Epub 2019 Jul 4 doi: 10.1016/j.idh.2019.06.002. PMID: 31279704
Stern A, Skalsky K, Avni T, Carrara E, Leibovici L, Paul M
Cochrane Database Syst Rev 2017 Dec 13;12(12):CD007720. doi: 10.1002/14651858.CD007720.pub3. PMID: 29236286Free PMC Article
Chalmers JD, Rother C, Salih W, Ewig S
Clin Infect Dis 2014 Feb;58(3):330-9. Epub 2013 Nov 22 doi: 10.1093/cid/cit734. PMID: 24270053

Supplemental Content

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