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Acute respiratory distress

MedGen UID:
677109
•Concept ID:
C0748355
•
Sign or Symptom
Synonym: Acute Respiratory Distress
SNOMED CT: Acute respiratory distress (373895009)

Definition

An abrupt onset of signs or symptoms indicating difficulty breathing including alterations in breath sounds and rate, chest retractions and color changes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcute respiratory distress

Professional guidelines

PubMed

An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline.
Qadir N, Sahetya S, Munshi L, Summers C, Abrams D, Beitler J, Bellani G, Brower RG, Burry L, Chen JT, Hodgson C, Hough CL, Lamontagne F, Law A, Papazian L, Pham T, Rubin E, Siuba M, Telias I, Patolia S, Chaudhuri D, Walkey A, Rochwerg B, Fan E
Am J Respir Crit Care Med 2024 Jan 1;209(1):24-36. doi: 10.1164/rccm.202311-2011ST. PMID: 38032683Free PMC Article
Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2).
Emeriaud G, López-Fernández YM, Iyer NP, Bembea MM, Agulnik A, Barbaro RP, Baudin F, Bhalla A, Brunow de Carvalho W, Carroll CL, Cheifetz IM, Chisti MJ, Cruces P, Curley MAQ, Dahmer MK, Dalton HJ, Erickson SJ, Essouri S, Fernández A, Flori HR, Grunwell JR, Jouvet P, Killien EY, Kneyber MCJ, Kudchadkar SR, Korang SK, Lee JH, Macrae DJ, Maddux A, Modesto I Alapont V, Morrow BM, Nadkarni VM, Napolitano N, Newth CJL, Pons-Odena M, Quasney MW, Rajapreyar P, Rambaud J, Randolph AG, Rimensberger P, Rowan CM, Sanchez-Pinto LN, Sapru A, Sauthier M, Shein SL, Smith LS, Steffen K, Takeuchi M, Thomas NJ, Tse SM, Valentine S, Ward S, Watson RS, Yehya N, Zimmerman JJ, Khemani RG; Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) Group on behalf of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network
Pediatr Crit Care Med 2023 Feb 1;24(2):143-168. Epub 2023 Jan 20 doi: 10.1097/PCC.0000000000003147. PMID: 36661420Free PMC Article
Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management.
Gorman EA, O'Kane CM, McAuley DF
Lancet 2022 Oct 1;400(10358):1157-1170. Epub 2022 Sep 4 doi: 10.1016/S0140-6736(22)01439-8. PMID: 36070788

Recent clinical studies

Etiology

Acute respiratory distress syndrome heterogeneity and the septic ARDS subgroup.
Xu H, Sheng S, Luo W, Xu X, Zhang Z
Front Immunol 2023;14:1277161. Epub 2023 Nov 14 doi: 10.3389/fimmu.2023.1277161. PMID: 38035100Free PMC Article
Management of severe acute respiratory distress syndrome: a primer.
Grotberg JC, Reynolds D, Kraft BD
Crit Care 2023 Jul 18;27(1):289. doi: 10.1186/s13054-023-04572-w. PMID: 37464381Free PMC Article
Acute Respiratory Distress Syndrome.
Gragossian A, Siuba MT
Emerg Med Clin North Am 2022 Aug;40(3):459-472. Epub 2022 May 10 doi: 10.1016/j.emc.2022.05.002. PMID: 35953211Free PMC Article
Acute Respiratory Distress Syndrome: Etiology, Pathogenesis, and Summary on Management.
Kaku S, Nguyen CD, Htet NN, Tutera D, Barr J, Paintal HS, Kuschner WG
J Intensive Care Med 2020 Aug;35(8):723-737. Epub 2019 Jun 17 doi: 10.1177/0885066619855021. PMID: 31208266
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.
Acute Respiratory Distress Syndrome Network, Brower RG, Matthay MA, Morris A, Schoenfeld D, Thompson BT, Wheeler A
N Engl J Med 2000 May 4;342(18):1301-8. doi: 10.1056/NEJM200005043421801. PMID: 10793162

Diagnosis

Redefining ARDS: a paradigm shift.
Villar J, Szakmany T, Grasselli G, Camporota L
Crit Care 2023 Oct 31;27(1):416. doi: 10.1186/s13054-023-04699-w. PMID: 37907946Free PMC Article
Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management.
Gorman EA, O'Kane CM, McAuley DF
Lancet 2022 Oct 1;400(10358):1157-1170. Epub 2022 Sep 4 doi: 10.1016/S0140-6736(22)01439-8. PMID: 36070788
Acute Respiratory Distress Syndrome.
Gragossian A, Siuba MT
Emerg Med Clin North Am 2022 Aug;40(3):459-472. Epub 2022 May 10 doi: 10.1016/j.emc.2022.05.002. PMID: 35953211Free PMC Article
Acute Amiodarone Pulmonary Toxicity.
Feduska ET, Thoma BN, Torjman MC, Goldhammer JE
J Cardiothorac Vasc Anesth 2021 May;35(5):1485-1494. Epub 2020 Nov 5 doi: 10.1053/j.jvca.2020.10.060. PMID: 33262034
Acute Respiratory Distress Syndrome: Advances in Diagnosis and Treatment.
Fan E, Brodie D, Slutsky AS
JAMA 2018 Feb 20;319(7):698-710. doi: 10.1001/jama.2017.21907. PMID: 29466596

Therapy

Fluid Therapy for Critically Ill Adults With Sepsis: A Review.
Zampieri FG, Bagshaw SM, Semler MW
JAMA 2023 Jun 13;329(22):1967-1980. doi: 10.1001/jama.2023.7560. PMID: 37314271
Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis.
Munshi L, Walkey A, Goligher E, Pham T, Uleryk EM, Fan E
Lancet Respir Med 2019 Feb;7(2):163-172. Epub 2019 Jan 11 doi: 10.1016/S2213-2600(18)30452-1. PMID: 30642776
Prone Position for Acute Respiratory Distress Syndrome. A Systematic Review and Meta-Analysis.
Munshi L, Del Sorbo L, Adhikari NKJ, Hodgson CL, Wunsch H, Meade MO, Uleryk E, Mancebo J, Pesenti A, Ranieri VM, Fan E
Ann Am Thorac Soc 2017 Oct;14(Supplement_4):S280-S288. doi: 10.1513/AnnalsATS.201704-343OT. PMID: 29068269
Prone position in acute respiratory distress syndrome. Rationale, indications, and limits.
Gattinoni L, Taccone P, Carlesso E, Marini JJ
Am J Respir Crit Care Med 2013 Dec 1;188(11):1286-93. doi: 10.1164/rccm.201308-1532CI. PMID: 24134414
The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination.
Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R
Am J Respir Crit Care Med 1994 Mar;149(3 Pt 1):818-24. doi: 10.1164/ajrccm.149.3.7509706. PMID: 7509706

Prognosis

Ventilatory Variables and Mechanical Power in Patients with Acute Respiratory Distress Syndrome.
Costa ELV, Slutsky AS, Brochard LJ, Brower R, Serpa-Neto A, Cavalcanti AB, Mercat A, Meade M, Morais CCA, Goligher E, Carvalho CRR, Amato MBP
Am J Respir Crit Care Med 2021 Aug 1;204(3):303-311. doi: 10.1164/rccm.202009-3467OC. PMID: 33784486
Critical Care Nephrology: Core Curriculum 2020.
Griffin BR, Liu KD, Teixeira JP
Am J Kidney Dis 2020 Mar;75(3):435-452. Epub 2020 Jan 22 doi: 10.1053/j.ajkd.2019.10.010. PMID: 31982214Free PMC Article
Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis.
Munshi L, Walkey A, Goligher E, Pham T, Uleryk EM, Fan E
Lancet Respir Med 2019 Feb;7(2):163-172. Epub 2019 Jan 11 doi: 10.1016/S2213-2600(18)30452-1. PMID: 30642776
Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study.
Khemani RG, Smith L, Lopez-Fernandez YM, Kwok J, Morzov R, Klein MJ, Yehya N, Willson D, Kneyber MCJ, Lillie J, Fernandez A, Newth CJL, Jouvet P, Thomas NJ; Pediatric Acute Respiratory Distress syndrome Incidence and Epidemiology (PARDIE) Investigators; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network
Lancet Respir Med 2019 Feb;7(2):115-128. Epub 2018 Oct 22 doi: 10.1016/S2213-2600(18)30344-8. PMID: 30361119Free PMC Article
Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries.
Bellani G, Laffey JG, Pham T, Fan E, Brochard L, Esteban A, Gattinoni L, van Haren F, Larsson A, McAuley DF, Ranieri M, Rubenfeld G, Thompson BT, Wrigge H, Slutsky AS, Pesenti A; LUNG SAFE Investigators; ESICM Trials Group
JAMA 2016 Feb 23;315(8):788-800. doi: 10.1001/jama.2016.0291. PMID: 26903337

Clinical prediction guides

Subphenotypes in patients with acute respiratory distress syndrome treated with high-flow oxygen.
Blot PL, Chousterman BG, Santafè M, Cartailler J, Pacheco A, Magret M, Masclans JR, Artigas A, Roca O, García-de-Acilu M
Crit Care 2023 Nov 1;27(1):419. doi: 10.1186/s13054-023-04687-0. PMID: 37915062Free PMC Article
Lung Ultrasound Prediction Model for Acute Respiratory Distress Syndrome: A Multicenter Prospective Observational Study.
Smit MR, Hagens LA, Heijnen NFL, Pisani L, Cherpanath TGV, Dongelmans DA, de Grooth HS, Pierrakos C, Tuinman PR, Zimatore C, Paulus F, Schnabel RM, Schultz MJ, Bergmans DCJJ, Bos LDJ; DARTS Consortium members
Am J Respir Crit Care Med 2023 Jun 15;207(12):1591-1601. doi: 10.1164/rccm.202210-1882OC. PMID: 36790377Free PMC Article
Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia.
Han X, Fan Y, Alwalid O, Li N, Jia X, Yuan M, Li Y, Cao Y, Gu J, Wu H, Shi H
Radiology 2021 Apr;299(1):E177-E186. Epub 2021 Jan 26 doi: 10.1148/radiol.2021203153. PMID: 33497317Free PMC Article
Acute respiratory distress syndrome in acute pancreatitis.
Shah J, Rana SS
Indian J Gastroenterol 2020 Apr;39(2):123-132. Epub 2020 Apr 13 doi: 10.1007/s12664-020-01016-z. PMID: 32285399
Biomarkers and Right Ventricular Dysfunction.
Pradhan NM, Mullin C, Poor HD
Crit Care Clin 2020 Jan;36(1):141-153. Epub 2019 Oct 21 doi: 10.1016/j.ccc.2019.08.011. PMID: 31733676Free PMC Article

Recent systematic reviews

Safety and efficacy of corticosteroids in ARDS patients: a systematic review and meta-analysis of RCT data.
Chang X, Li S, Fu Y, Dang H, Liu C
Respir Res 2022 Nov 4;23(1):301. doi: 10.1186/s12931-022-02186-4. PMID: 36333729Free PMC Article
Positioning for acute respiratory distress in hospitalised infants and children.
Bhandari AP, Nnate DA, Vasanthan L, Konstantinidis M, Thompson J
Cochrane Database Syst Rev 2022 Jun 6;6(6):CD003645. doi: 10.1002/14651858.CD003645.pub4. PMID: 35661343Free PMC Article
Prone Position for Acute Respiratory Distress Syndrome. A Systematic Review and Meta-Analysis.
Munshi L, Del Sorbo L, Adhikari NKJ, Hodgson CL, Wunsch H, Meade MO, Uleryk E, Mancebo J, Pesenti A, Ranieri VM, Fan E
Ann Am Thorac Soc 2017 Oct;14(Supplement_4):S280-S288. doi: 10.1513/AnnalsATS.201704-343OT. PMID: 29068269
Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.
Annane D, Pastores SM, Rochwerg B, Arlt W, Balk RA, Beishuizen A, Briegel J, Carcillo J, Christ-Crain M, Cooper MS, Marik PE, Umberto Meduri G, Olsen KM, Rodgers S, Russell JA, Van den Berghe G
Intensive Care Med 2017 Dec;43(12):1751-1763. Epub 2017 Sep 21 doi: 10.1007/s00134-017-4919-5. PMID: 28940011
Corticosteroids in septic shock: a systematic review and network meta-analysis.
Gibbison B, López-López JA, Higgins JP, Miller T, Angelini GD, Lightman SL, Annane D
Crit Care 2017 Mar 28;21(1):78. doi: 10.1186/s13054-017-1659-4. PMID: 28351429Free PMC Article

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