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Lightheadedness

MedGen UID:
65105
•Concept ID:
C0220870
•
Sign or Symptom
Synonyms: Light Headedness; Light-Headedness
SNOMED CT: Lightheadedness (386705008); Light-headedness (386705008); Feels light headed (386705008); Lightheaded (386705008); Dizziness - light-headed (386705008); Wooziness (386705008)

Definition

A feeling of faintness; a reeling sensation. Lightheadedness is medically distinct from dizziness, unsteadiness, and vertigo. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLightheadedness

Professional guidelines

PubMed

Essential thrombocythemia: 2024 update on diagnosis, risk stratification, and management.
Tefferi A, Vannucchi AM, Barbui T
Am J Hematol 2024 Apr;99(4):697-718. Epub 2024 Jan 25 doi: 10.1002/ajh.27216. PMID: 38269572
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Dizziness: Approach to Evaluation and Management.
Muncie HL, Sirmans SM, James E
Am Fam Physician 2017 Feb 1;95(3):154-162. PMID: 28145669

Recent clinical studies

Etiology

Essential thrombocythemia: 2024 update on diagnosis, risk stratification, and management.
Tefferi A, Vannucchi AM, Barbui T
Am J Hematol 2024 Apr;99(4):697-718. Epub 2024 Jan 25 doi: 10.1002/ajh.27216. PMID: 38269572
Orthostatic Hypotension: A Practical Approach.
Kim MJ, Farrell J
Am Fam Physician 2022 Jan 1;105(1):39-49. PMID: 35029940
Management of Orthostatic Hypotension in Parkinson's Disease.
Fanciulli A, Leys F, Falup-Pecurariu C, Thijs R, Wenning GK
J Parkinsons Dis 2020;10(s1):S57-S64. doi: 10.3233/JPD-202036. PMID: 32716319Free PMC Article
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Gepirone hydrochloride: a novel antidepressant with 5-HT1A agonistic properties.
Kaur Gill A, Bansal Y, Bhandari R, Kaur S, Kaur J, Singh R, Kuhad A, Kuhad A
Drugs Today (Barc) 2019 Jul;55(7):423-437. doi: 10.1358/dot.2019.55.7.2958474. PMID: 31347611

Diagnosis

Postural Orthostatic Tachycardia Syndrome (POTS): An Update for Clinical Practice.
Sebastian SA, Co EL, Panthangi V, Jain E, Ishak A, Shah Y, Vasavada A, Padda I
Curr Probl Cardiol 2022 Dec;47(12):101384. Epub 2022 Aug 31 doi: 10.1016/j.cpcardiol.2022.101384. PMID: 36055438
Sinus Node Dysfunction.
Hawks MK, Paul MLB, Malu OO
Am Fam Physician 2021 Aug 1;104(2):179-185. PMID: 34383451
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Dizziness: Approach to Evaluation and Management.
Muncie HL, Sirmans SM, James E
Am Fam Physician 2017 Feb 1;95(3):154-162. PMID: 28145669
Dizziness: a diagnostic approach.
Post RE, Dickerson LM
Am Fam Physician 2010 Aug 15;82(4):361-8, 369. PMID: 20704166

Therapy

Postural Orthostatic Tachycardia Syndrome (POTS): An Update for Clinical Practice.
Sebastian SA, Co EL, Panthangi V, Jain E, Ishak A, Shah Y, Vasavada A, Padda I
Curr Probl Cardiol 2022 Dec;47(12):101384. Epub 2022 Aug 31 doi: 10.1016/j.cpcardiol.2022.101384. PMID: 36055438
Patient-centred approaches for the management of unpleasant symptoms in kidney disease.
Kalantar-Zadeh K, Lockwood MB, Rhee CM, Tantisattamo E, Andreoli S, Balducci A, Laffin P, Harris T, Knight R, Kumaraswami L, Liakopoulos V, Lui SF, Kumar S, Ng M, Saadi G, Ulasi I, Tong A, Li PK
Nat Rev Nephrol 2022 Mar;18(3):185-198. Epub 2022 Jan 3 doi: 10.1038/s41581-021-00518-z. PMID: 34980890
Safety of low-dose oral minoxidil for hair loss: A multicenter study of 1404 patients.
Vañó-Galván S, Pirmez R, Hermosa-Gelbard A, Moreno-Arrones ÓM, Saceda-Corralo D, Rodrigues-Barata R, Jimenez-Cauhe J, Koh WL, Poa JE, Jerjen R, Trindade de Carvalho L, John JM, Salas-Callo CI, Vincenzi C, Yin L, Lo-Sicco K, Waskiel-Burnat A, Starace M, Zamorano JL, Jaén-Olasolo P, Piraccini BM, Rudnicka L, Shapiro J, Tosti A, Sinclair R, Bhoyrul B
J Am Acad Dermatol 2021 Jun;84(6):1644-1651. Epub 2021 Feb 24 doi: 10.1016/j.jaad.2021.02.054. PMID: 33639244
Idiopathic anaphylaxis.
Guo C, Greenberger PA
Allergy Asthma Proc 2019 Nov 1;40(6):457-461. doi: 10.2500/aap.2019.40.4271. PMID: 31690394
Gepirone hydrochloride: a novel antidepressant with 5-HT1A agonistic properties.
Kaur Gill A, Bansal Y, Bhandari R, Kaur S, Kaur J, Singh R, Kuhad A, Kuhad A
Drugs Today (Barc) 2019 Jul;55(7):423-437. doi: 10.1358/dot.2019.55.7.2958474. PMID: 31347611

Prognosis

Essential thrombocythemia: 2024 update on diagnosis, risk stratification, and management.
Tefferi A, Vannucchi AM, Barbui T
Am J Hematol 2024 Apr;99(4):697-718. Epub 2024 Jan 25 doi: 10.1002/ajh.27216. PMID: 38269572
Orthostatic Intolerance and Chiari I Malformation.
Petracek LS, Rowe PC
Neurosurg Clin N Am 2023 Jan;34(1):43-54. doi: 10.1016/j.nec.2022.09.002. PMID: 36424063
Sinus Node Dysfunction.
Hawks MK, Paul MLB, Malu OO
Am Fam Physician 2021 Aug 1;104(2):179-185. PMID: 34383451
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Migraine-associated vestibulopathy.
Honaker J, Samy RN
Curr Opin Otolaryngol Head Neck Surg 2008 Oct;16(5):412-5. doi: 10.1097/MOO.0b013e32830a4a02. PMID: 18797281

Clinical prediction guides

Sinus Node Dysfunction.
Hawks MK, Paul MLB, Malu OO
Am Fam Physician 2021 Aug 1;104(2):179-185. PMID: 34383451
Episodic Spontaneous Dizziness.
Eggers SDZ
Continuum (Minneap Minn) 2021 Apr 1;27(2):369-401. doi: 10.1212/CON.0000000000000931. PMID: 34351111
Safety of low-dose oral minoxidil for hair loss: A multicenter study of 1404 patients.
Vañó-Galván S, Pirmez R, Hermosa-Gelbard A, Moreno-Arrones ÓM, Saceda-Corralo D, Rodrigues-Barata R, Jimenez-Cauhe J, Koh WL, Poa JE, Jerjen R, Trindade de Carvalho L, John JM, Salas-Callo CI, Vincenzi C, Yin L, Lo-Sicco K, Waskiel-Burnat A, Starace M, Zamorano JL, Jaén-Olasolo P, Piraccini BM, Rudnicka L, Shapiro J, Tosti A, Sinclair R, Bhoyrul B
J Am Acad Dermatol 2021 Jun;84(6):1644-1651. Epub 2021 Feb 24 doi: 10.1016/j.jaad.2021.02.054. PMID: 33639244
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Gepirone hydrochloride: a novel antidepressant with 5-HT1A agonistic properties.
Kaur Gill A, Bansal Y, Bhandari R, Kaur S, Kaur J, Singh R, Kuhad A, Kuhad A
Drugs Today (Barc) 2019 Jul;55(7):423-437. doi: 10.1358/dot.2019.55.7.2958474. PMID: 31347611

Recent systematic reviews

Serotonin 3 receptor antagonists for obsessive-compulsive disorder: A systematic review and pairwise meta-analysis.
Hamanaka S, Kishi T, Sakuma K, Nishii Y, Hatano M, Iwata N
J Psychiatr Res 2023 Nov;167:132-138. Epub 2023 Oct 16 doi: 10.1016/j.jpsychires.2023.10.029. PMID: 37866327
Postural Orthostatic Tachycardia Syndrome After COVID-19: A Systematic Review of Therapeutic Interventions.
Abbate G, De Iulio B, Thomas G, Priday A, Biondi-Zoccai G, Markley R, Abbate A
J Cardiovasc Pharmacol 2023 Jul 1;82(1):23-31. doi: 10.1097/FJC.0000000000001432. PMID: 37094584
Adverse Events of Injectable Deoxycholic Acid.
Pham CT, Lee A, Sung CT, Choi F, Juhasz M, Mesinkovska NA
Dermatol Surg 2020 Jul;46(7):942-949. doi: 10.1097/DSS.0000000000002318. PMID: 31977503
Oxycodone for cancer-related pain.
Schmidt-Hansen M, Bennett MI, Arnold S, Bromham N, Hilgart JS
Cochrane Database Syst Rev 2017 Aug 22;8(8):CD003870. doi: 10.1002/14651858.CD003870.pub6. PMID: 28829910Free PMC Article
Exercise-based rehabilitation programmes for pulmonary hypertension.
Morris NR, Kermeen FD, Holland AE
Cochrane Database Syst Rev 2017 Jan 19;1(1):CD011285. doi: 10.1002/14651858.CD011285.pub2. PMID: 28099988Free PMC Article

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