U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Multiple meningiomas

MedGen UID:
64453
•Concept ID:
C0205834
•
Neoplastic Process
Synonyms: Meningioma, Multiple; Meningiomas, Multiple; Meningiomatoses; Meningiomatosis; Multiple Meningioma; Multiple Meningiomas
SNOMED CT: Meningiomatosis (40935003); Diffuse meningiomatosis (40935003); Multiple meningiomas (40935003)
 
HPO: HP:0033714

Definition

The occurrence of multiple distinct meningiomas in the same individual. [from HPO]

Professional guidelines

PubMed

The role of mifepristone in the management of meningiomas: A systematic review of literature.
Sharma R, Garg K, Katiyar V, Tandon V, Agarwal D, Singh M, Chandra SP, Suri A, Kale SS, Mahapatra AK
Neurol India 2019 May-Jun;67(3):698-705. doi: 10.4103/0028-3886.263232. PMID: 31347538
Fertility treatment is associated with multiple meningiomas and younger age at diagnosis.
Shahin MN, Magill ST, Dalle Ore CL, Viner JA, Peters PN, Solomon DA, McDermott MW
J Neurooncol 2019 May;143(1):137-144. Epub 2019 Mar 13 doi: 10.1007/s11060-019-03147-6. PMID: 30868355Free PMC Article
Management of pediatric intracranial meningiomas: an analysis of 31 cases and review of literature.
Ravindranath K, Vasudevan MC, Pande A, Symss N
Childs Nerv Syst 2013 Apr;29(4):573-82. Epub 2013 Jan 5 doi: 10.1007/s00381-012-2010-7. PMID: 23292441

Recent clinical studies

Etiology

Endovascular stenting for cerebral venous sinus stenosis secondary to meningioma invasion.
Ahmed G, Abou-Foul M, Sage W, McConachie N
Neuroradiology 2024 May;66(5):817-824. Epub 2024 Mar 2 doi: 10.1007/s00234-024-03321-2. PMID: 38429544
Multiple meningiomas in a woman irradiated in utero.
Chen AS, Drummond KJ, Jallad MM, Paldor I
J Clin Neurosci 2016 Nov;33:225-227. Epub 2016 Sep 6 doi: 10.1016/j.jocn.2016.03.030. PMID: 27612673
Meningiomas and neurofibromatosis.
Goutagny S, Kalamarides M
J Neurooncol 2010 Sep;99(3):341-7. Epub 2010 Aug 17 doi: 10.1007/s11060-010-0339-x. PMID: 20714782
Multiple meningiomas within the spinal canal: case report with 23 tumors.
Silva JA, Holanda MM, Araújo AF, Mello RV
Arq Neuropsiquiatr 2005 Mar;63(1):166-70. Epub 2005 Apr 13 doi: 10.1590/s0004-282x2005000100031. PMID: 15830086
Correlation between cytogenetic and histopathological findings in 65 human meningiomas.
Casalone R, Simi P, Granata P, Minelli E, Giudici A, Butti G, Solero CL
Cancer Genet Cytogenet 1990 Apr;45(2):237-43. doi: 10.1016/0165-4608(90)90088-r. PMID: 2317772

Diagnosis

SMARCE1-related meningiomas: A clear example of cancer predisposing syndrome.
Fiorentini E, Giunti L, Di Rita A, Peraio S, Fonte C, Caporalini C, Buccoliero AM, Censullo ML, Gori G, Noris A, Pasquariello R, Battini R, Pavone R, Giordano F, Giglio S, Rinaldi B
Eur J Med Genet 2023 Jul;66(7):104784. Epub 2023 May 8 doi: 10.1016/j.ejmg.2023.104784. PMID: 37164167
Neurofibromatosis Type 2 (NF2) and the Implications for Vestibular Schwannoma and Meningioma Pathogenesis.
Bachir S, Shah S, Shapiro S, Koehler A, Mahammedi A, Samy RN, Zuccarello M, Schorry E, Sengupta S
Int J Mol Sci 2021 Jan 12;22(2) doi: 10.3390/ijms22020690. PMID: 33445724Free PMC Article
Neurofibromatosis type 2.
Slattery WH
Otolaryngol Clin North Am 2015 Jun;48(3):443-60. doi: 10.1016/j.otc.2015.02.005. PMID: 26043141
Simultaneous occurrence of multiple meningiomas in different neuraxial compartments.
Bhatoe HS
Neurol India 2003 Jun;51(2):263-5. PMID: 14571022
Central neurofibromatosis.
Banerjee AK, Radhakrishnan K, Sawhney IM, Gulati DR
Clin Neurol Neurosurg 1982;84(3):191-9. doi: 10.1016/0303-8467(82)90042-7. PMID: 6295683

Therapy

Sporadic and neurofibromatosis type 2-associated meningioma in children and adolescents.
Wagener K, Beckhaus J, Boekhoff S, Friedrich C, Müller HL
J Neurooncol 2023 Jul;163(3):555-563. Epub 2023 Jul 4 doi: 10.1007/s11060-023-04344-0. PMID: 37402092
Dramatic Shrinkage with Reduced Vascularization of Large Meningiomas After Cessation of Progestin Treatment.
Kalamarides M, Peyre M
World Neurosurg 2017 May;101:814.e7-814.e10. Epub 2017 Mar 12 doi: 10.1016/j.wneu.2017.03.013. PMID: 28300711
Radiation-Induced Meningiomas: An Exhaustive Review of the Literature.
Yamanaka R, Hayano A, Kanayama T
World Neurosurg 2017 Jan;97:635-644.e8. Epub 2016 Oct 3 doi: 10.1016/j.wneu.2016.09.094. PMID: 27713063
Meningiomas in lymphangioleiomyomatosis.
Moss J, DeCastro R, Patronas NJ, Taveira-DaSilva A
JAMA 2001 Oct 17;286(15):1879-81. doi: 10.1001/jama.286.15.1879. PMID: 11597290
Multiple meningiomas in the spinal canal.
Patronas NJ, Brown F, Duda EE
Surg Neurol 1980 Jan;13(1):78-80. PMID: 7361263

Prognosis

Description of Two Families with New Mutations in Familial Cerebral Cavernous Malformations Genes.
Iruzubieta P, Campo-Caballero D, Equiza J, Albajar I, Sulibarría N, Sáez R, Andrés N, Mondragón E, Zulaica M, de Arce A, Urtasun M, López de Munain A
J Stroke Cerebrovasc Dis 2021 Dec;30(12):106130. Epub 2021 Sep 29 doi: 10.1016/j.jstrokecerebrovasdis.2021.106130. PMID: 34597987
Management of multiple meningiomas.
Tsermoulas G, Turel MK, Wilcox JT, Shultz D, Farb R, Zadeh G, Bernstein M
J Neurosurg 2018 May;128(5):1403-1409. Epub 2017 Jul 21 doi: 10.3171/2017.2.JNS162608. PMID: 28731398
Meningiomas and neurofibromatosis.
Goutagny S, Kalamarides M
J Neurooncol 2010 Sep;99(3):341-7. Epub 2010 Aug 17 doi: 10.1007/s11060-010-0339-x. PMID: 20714782
MR spectroscopy in patients with intracranial meningiomas.
Buhl R, Nabavi A, Wolff S, Hugo HH, Alfke K, Jansen O, Mehdorn HM
Neurol Res 2007 Jan;29(1):43-6. doi: 10.1179/174313206X153824. PMID: 17427274
Recurrence of meningiomas.
Yamasaki F, Yoshioka H, Hama S, Sugiyama K, Arita K, Kurisu K
Cancer 2000 Sep 1;89(5):1102-10. doi: 10.1002/1097-0142(20000901)89:5<1102::aid-cncr20>3.0.co;2-l. PMID: 10964341

Clinical prediction guides

Multiple Intracranial Meningiomas: A Case Series and Review of the Literature.
Araújo Pereira BJ, Nogueira de Almeida A, Pires de Aguiar PH, Paiva WS, Teixeira MJ, Nagahashi Marie SK
World Neurosurg 2019 Feb;122:e1536-e1541. Epub 2018 Nov 22 doi: 10.1016/j.wneu.2018.11.097. PMID: 30471445
Management of multiple meningiomas.
Tsermoulas G, Turel MK, Wilcox JT, Shultz D, Farb R, Zadeh G, Bernstein M
J Neurosurg 2018 May;128(5):1403-1409. Epub 2017 Jul 21 doi: 10.3171/2017.2.JNS162608. PMID: 28731398
Dramatic Shrinkage with Reduced Vascularization of Large Meningiomas After Cessation of Progestin Treatment.
Kalamarides M, Peyre M
World Neurosurg 2017 May;101:814.e7-814.e10. Epub 2017 Mar 12 doi: 10.1016/j.wneu.2017.03.013. PMID: 28300711
MR spectroscopy in patients with intracranial meningiomas.
Buhl R, Nabavi A, Wolff S, Hugo HH, Alfke K, Jansen O, Mehdorn HM
Neurol Res 2007 Jan;29(1):43-6. doi: 10.1179/174313206X153824. PMID: 17427274
Familial meningioma is not allelic to neurofibromatosis 2.
Pulst SM, Rouleau GA, Marineau C, Fain P, Sieb JP
Neurology 1993 Oct;43(10):2096-8. doi: 10.1212/wnl.43.10.2096. PMID: 8413972

Recent systematic reviews

The role of mifepristone in the management of meningiomas: A systematic review of literature.
Sharma R, Garg K, Katiyar V, Tandon V, Agarwal D, Singh M, Chandra SP, Suri A, Kale SS, Mahapatra AK
Neurol India 2019 May-Jun;67(3):698-705. doi: 10.4103/0028-3886.263232. PMID: 31347538
Surgery versus stereotactic radiosurgery for the treatment of multiple meningiomas in neurofibromatosis type 2: illustrative case and systematic review.
Nguyen T, Chung LK, Sheppard JP, Bhatt NS, Chen CHJ, Lagman C, Kaprealian T, Lee P, Nghiemphu PL, Yang I
Neurosurg Rev 2019 Mar;42(1):85-96. Epub 2017 Sep 13 doi: 10.1007/s10143-017-0904-2. PMID: 28900754

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...