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Juvenile spondyloarthropathy

MedGen UID:
592564
•Concept ID:
C0409676
•
Disease or Syndrome
Synonyms: JSpA; Juvenile Spondyloarthritis; juvenile Spondyloarthritis; juvenile spondyloarthropathy
SNOMED CT: Juvenile spondyloarthropathy (239806000)
 
Monarch Initiative: MONDO:0043377

Definition

A group of chronic, inflammatory childhood diseases characterized by arthritis and enthesitis. This disorder can affect the axial skeleton in late childhood or young adulthood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVJuvenile spondyloarthropathy

Professional guidelines

PubMed

Magnetic resonance imaging findings in juvenile spondyloarthropathy and effects of treatment observed on subsequent imaging.
Lin C, MacKenzie JD, Courtier JL, Gu JT, Milojevic D
Pediatr Rheumatol Online J 2014;12:25. Epub 2014 Jul 11 doi: 10.1186/1546-0096-12-25. PMID: 25067925Free PMC Article
Diagnosis and treatment of juvenile spondyloarthropathy and related diseases.
Lin C, Milojevic D
Pediatr Ann 2012 Nov;41(11) doi: 10.3928/00904481-20121022-11. PMID: 23814933
Evaluation of ILAR classification criteria for juvenile idiopathic arthritis in Spanish children.
Merino R, De Inocencio J, García-Consuegra J
J Rheumatol 2001 Dec;28(12):2731-6. PMID: 11764225

Recent clinical studies

Etiology

Sacroiliitis in children and adolescents with familial Mediterranean fever.
Kaçmaz H, Aldemir E, Tanatar A, Karadağ ŞG, Çakan M, Sönmez HE, Ayaz NA
Adv Rheumatol 2021 Jun 5;61(1):29. doi: 10.1186/s42358-021-00188-2. PMID: 34090528
Unexpected increase of aortic stiffness in juvenile Spondyloarthropathies.
Dedeoglu R, Yildiz M, Karagozlu F, Oztunc F, Ulug N, Akdeniz B, Adrovic A, Haslak F, Sahin S, Barut K, Kasapcopur O
Cardiol Young 2020 Dec;30(12):1806-1814. Epub 2020 Sep 17 doi: 10.1017/S1047951120002796. PMID: 32938508
The frequency of uveitis in patients with juvenile inflammatory rheumatic diseases.
Hayworth JL, Turk MA, Nevskaya T, Pope JE
Joint Bone Spine 2019 Nov;86(6):685-690. Epub 2019 Jun 14 doi: 10.1016/j.jbspin.2019.06.001. PMID: 31207292
Enthesitis-related arthritis.
Aggarwal A, Misra DP
Clin Rheumatol 2015 Nov;34(11):1839-46. Epub 2015 Aug 2 doi: 10.1007/s10067-015-3029-4. PMID: 26233720
Juvenile spondyloarthropathy.
Tse SM, Laxer RM
Curr Opin Rheumatol 2003 Jul;15(4):374-9. doi: 10.1097/00002281-200307000-00002. PMID: 12819463

Diagnosis

MRI in pediatric sacroiliitis, what radiologists should know.
Herregods N, Anisau A, Schiettecatte E, Vereecke E, Morbée L, Laloo F, Jaremko JL, Jans L
Pediatr Radiol 2023 Jul;53(8):1576-1586. Epub 2023 Mar 1 doi: 10.1007/s00247-023-05602-z. PMID: 36856758
The frequency of uveitis in patients with juvenile inflammatory rheumatic diseases.
Hayworth JL, Turk MA, Nevskaya T, Pope JE
Joint Bone Spine 2019 Nov;86(6):685-690. Epub 2019 Jun 14 doi: 10.1016/j.jbspin.2019.06.001. PMID: 31207292
Enthesitis-related arthritis.
Aggarwal A, Misra DP
Clin Rheumatol 2015 Nov;34(11):1839-46. Epub 2015 Aug 2 doi: 10.1007/s10067-015-3029-4. PMID: 26233720
Diagnosis and treatment of juvenile spondyloarthropathy and related diseases.
Lin C, Milojevic D
Pediatr Ann 2012 Nov;41(11) doi: 10.3928/00904481-20121022-11. PMID: 23814933
Juvenile spondyloarthropathies.
Scofield RH, Sestak AL
Curr Rheumatol Rep 2012 Oct;14(5):395-401. doi: 10.1007/s11926-012-0273-3. PMID: 22911266

Therapy

The frequency of uveitis in patients with juvenile inflammatory rheumatic diseases.
Hayworth JL, Turk MA, Nevskaya T, Pope JE
Joint Bone Spine 2019 Nov;86(6):685-690. Epub 2019 Jun 14 doi: 10.1016/j.jbspin.2019.06.001. PMID: 31207292
Enthesitis-related arthritis.
Aggarwal A, Misra DP
Clin Rheumatol 2015 Nov;34(11):1839-46. Epub 2015 Aug 2 doi: 10.1007/s10067-015-3029-4. PMID: 26233720
Magnetic resonance imaging findings in juvenile spondyloarthropathy and effects of treatment observed on subsequent imaging.
Lin C, MacKenzie JD, Courtier JL, Gu JT, Milojevic D
Pediatr Rheumatol Online J 2014;12:25. Epub 2014 Jul 11 doi: 10.1186/1546-0096-12-25. PMID: 25067925Free PMC Article
Radiographic and clinical outcome in early juvenile rheumatoid arthritis and juvenile spondyloarthropathy: a 3-year prospective study.
Selvaag AM, Flatø B, Dale K, Lien G, Vinje O, Smerdel-Ramoya A, Førre Ø
J Rheumatol 2006 Jul;33(7):1382-91. Epub 2006 Jun 1 PMID: 16758503
Juvenile spondyloarthropathies.
Pepmueller PH, Moore TL
Curr Opin Rheumatol 2000 Jul;12(4):269-73. doi: 10.1097/00002281-200007000-00006. PMID: 10910178

Prognosis

Unexpected increase of aortic stiffness in juvenile Spondyloarthropathies.
Dedeoglu R, Yildiz M, Karagozlu F, Oztunc F, Ulug N, Akdeniz B, Adrovic A, Haslak F, Sahin S, Barut K, Kasapcopur O
Cardiol Young 2020 Dec;30(12):1806-1814. Epub 2020 Sep 17 doi: 10.1017/S1047951120002796. PMID: 32938508
The frequency of uveitis in patients with juvenile inflammatory rheumatic diseases.
Hayworth JL, Turk MA, Nevskaya T, Pope JE
Joint Bone Spine 2019 Nov;86(6):685-690. Epub 2019 Jun 14 doi: 10.1016/j.jbspin.2019.06.001. PMID: 31207292
Enthesitis-related arthritis.
Aggarwal A, Misra DP
Clin Rheumatol 2015 Nov;34(11):1839-46. Epub 2015 Aug 2 doi: 10.1007/s10067-015-3029-4. PMID: 26233720
Relationship of psoriatic arthritis with the other spondyloarthropathies.
Helliwell PS
Curr Opin Rheumatol 2004 Jul;16(4):344-9. doi: 10.1097/01.bor.0000129717.19777.9d. PMID: 15201595
Juvenile spondyloarthropathy.
Tse SM, Laxer RM
Curr Opin Rheumatol 2003 Jul;15(4):374-9. doi: 10.1097/00002281-200307000-00002. PMID: 12819463

Clinical prediction guides

Recent updates in enthesitis-related arthritis.
Naveen R, Guleria S, Aggarwal A
Rheumatol Int 2023 Mar;43(3):409-420. Epub 2023 Jan 11 doi: 10.1007/s00296-023-05274-w. PMID: 36629936
Sacroiliitis in children and adolescents with familial Mediterranean fever.
Kaçmaz H, Aldemir E, Tanatar A, Karadağ ŞG, Çakan M, Sönmez HE, Ayaz NA
Adv Rheumatol 2021 Jun 5;61(1):29. doi: 10.1186/s42358-021-00188-2. PMID: 34090528
Evaluation of familial Mediterranean fever patients concomitant with juvenile spondyloarthropathy.
Paç Kısaarslan A, Şahin N, Özdemir Çiçek S, Gündüz Z, Poyrazoğlu H, Düşünsel R
Mod Rheumatol 2021 May;31(3):718-724. Epub 2020 Sep 7 doi: 10.1080/14397595.2020.1812809. PMID: 32815445
Unexpected increase of aortic stiffness in juvenile Spondyloarthropathies.
Dedeoglu R, Yildiz M, Karagozlu F, Oztunc F, Ulug N, Akdeniz B, Adrovic A, Haslak F, Sahin S, Barut K, Kasapcopur O
Cardiol Young 2020 Dec;30(12):1806-1814. Epub 2020 Sep 17 doi: 10.1017/S1047951120002796. PMID: 32938508
Relationship of psoriatic arthritis with the other spondyloarthropathies.
Helliwell PS
Curr Opin Rheumatol 2004 Jul;16(4):344-9. doi: 10.1097/01.bor.0000129717.19777.9d. PMID: 15201595

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