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Bile duct leakage

MedGen UID:
586542
•Concept ID:
C0400998
•
Pathologic Function
Synonym: Bile Duct Leakage
SNOMED CT: Bile duct leakage (235932003)

Definition

The leakage of bile into the abdominal cavity as a result of injury to the bile duct. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBile duct leakage

Professional guidelines

PubMed

Is there a role for endoscopic therapy as a definitive treatment for post-laparoscopic bile duct injuries?
Fatima J, Barton JG, Grotz TE, Geng Z, Harmsen WS, Huebner M, Baron TH, Kendrick ML, Donohue JH, Que FG, Nagorney DM, Farnell MB
J Am Coll Surg 2010 Oct;211(4):495-502. doi: 10.1016/j.jamcollsurg.2010.06.013. PMID: 20801692
Pathogenesis and treatment to postoperative bile leakage: report of 38 cases.
Zhang JM, Yu SA, Shen W, Zheng ZD
Hepatobiliary Pancreat Dis Int 2005 Aug;4(3):441-4. PMID: 16109533
Treatment of bile duct lesions after laparoscopic cholecystectomy.
Bergman JJ, van den Brink GR, Rauws EA, de Wit L, Obertop H, Huibregtse K, Tytgat GN, Gouma DJ
Gut 1996 Jan;38(1):141-7. doi: 10.1136/gut.38.1.141. PMID: 8566842Free PMC Article

Recent clinical studies

Etiology

Efficacy and safety of endoscopic retrograde cholangiopancreatography with endoscopic sphincterotomy and biliary stenting in post-operative bile leaks.
Çelik M, Yilmaz H, Kılıç MC, Soykan M, Akbudak İH, Ozban M, Yilmaz M
Ulus Travma Acil Cerrahi Derg 2023 Aug;29(8):904-908. doi: 10.14744/tjtes.2023.49963. PMID: 37563904Free PMC Article
Identification and management of subvesical bile duct leakage after laparoscopic cholecystectomy: A systematic review.
Carannante F, Mazzotta E, Miacci V, Bianco G, Mascianà G, D'Agostino F, Caricato M, Capolupo GT
Asian J Surg 2023 Oct;46(10):4161-4168. Epub 2023 Apr 29 doi: 10.1016/j.asjsur.2023.04.031. PMID: 37127504
Occlusion of the cystic duct with cyanoacrylate glue at laparoscopic subtotal fenestrating cholecystectomy for a difficult gallbladder.
Jenner DC, Klimovskij M, Nicholls M, Bates T
Acta Chir Belg 2022 Feb;122(1):23-28. Epub 2020 Nov 19 doi: 10.1080/00015458.2020.1846937. PMID: 33210557
The Effect of Preoperative Biliary Drainage with or without Pancreatic Stenting on Complications after Pancreatoduodenectomy: A Retrospective Cohort Study.
Chu J, He S, Ke Y, Liu X, Wang P, Zhang W, Qiu G, Wang C, Zhang J, Wang G
Biomed Res Int 2021;2021:5572395. Epub 2021 Apr 29 doi: 10.1155/2021/5572395. PMID: 33997014Free PMC Article
Same-admission versus interval cholecystectomy for mild gallstone pancreatitis (PONCHO): a multicentre randomised controlled trial.
da Costa DW, Bouwense SA, Schepers NJ, Besselink MG, van Santvoort HC, van Brunschot S, Bakker OJ, Bollen TL, Dejong CH, van Goor H, Boermeester MA, Bruno MJ, van Eijck CH, Timmer R, Weusten BL, Consten EC, Brink MA, Spanier BWM, Bilgen EJS, Nieuwenhuijs VB, Hofker HS, Rosman C, Voorburg AM, Bosscha K, van Duijvendijk P, Gerritsen JJ, Heisterkamp J, de Hingh IH, Witteman BJ, Kruyt PM, Scheepers JJ, Molenaar IQ, Schaapherder AF, Manusama ER, van der Waaij LA, van Unen J, Dijkgraaf MG, van Ramshorst B, Gooszen HG, Boerma D; Dutch Pancreatitis Study Group
Lancet 2015 Sep 26;386(10000):1261-1268. doi: 10.1016/S0140-6736(15)00274-3. PMID: 26460661

Diagnosis

Efficacy and safety of endoscopic retrograde cholangiopancreatography with endoscopic sphincterotomy and biliary stenting in post-operative bile leaks.
Çelik M, Yilmaz H, Kılıç MC, Soykan M, Akbudak İH, Ozban M, Yilmaz M
Ulus Travma Acil Cerrahi Derg 2023 Aug;29(8):904-908. doi: 10.14744/tjtes.2023.49963. PMID: 37563904Free PMC Article
Identification and management of subvesical bile duct leakage after laparoscopic cholecystectomy: A systematic review.
Carannante F, Mazzotta E, Miacci V, Bianco G, Mascianà G, D'Agostino F, Caricato M, Capolupo GT
Asian J Surg 2023 Oct;46(10):4161-4168. Epub 2023 Apr 29 doi: 10.1016/j.asjsur.2023.04.031. PMID: 37127504
Diagnostic and therapeutic single-operator cholangiopancreatoscopy with SpyGlassDS™: results of a multicenter retrospective cohort study.
Turowski F, Hügle U, Dormann A, Bechtler M, Jakobs R, Gottschalk U, Nötzel E, Hartmann D, Lorenz A, Kolligs F, Veltzke-Schlieker W, Adler A, Becker O, Wiedenmann B, Bürgel N, Tröger H, Schumann M, Daum S, Siegmund B, Bojarski C
Surg Endosc 2018 Sep;32(9):3981-3988. Epub 2018 Mar 12 doi: 10.1007/s00464-018-6141-0. PMID: 29532224
Same-admission versus interval cholecystectomy for mild gallstone pancreatitis (PONCHO): a multicentre randomised controlled trial.
da Costa DW, Bouwense SA, Schepers NJ, Besselink MG, van Santvoort HC, van Brunschot S, Bakker OJ, Bollen TL, Dejong CH, van Goor H, Boermeester MA, Bruno MJ, van Eijck CH, Timmer R, Weusten BL, Consten EC, Brink MA, Spanier BWM, Bilgen EJS, Nieuwenhuijs VB, Hofker HS, Rosman C, Voorburg AM, Bosscha K, van Duijvendijk P, Gerritsen JJ, Heisterkamp J, de Hingh IH, Witteman BJ, Kruyt PM, Scheepers JJ, Molenaar IQ, Schaapherder AF, Manusama ER, van der Waaij LA, van Unen J, Dijkgraaf MG, van Ramshorst B, Gooszen HG, Boerma D; Dutch Pancreatitis Study Group
Lancet 2015 Sep 26;386(10000):1261-1268. doi: 10.1016/S0140-6736(15)00274-3. PMID: 26460661
Endoscopic treatment of post-surgical bile duct injuries: long term outcome and predictors of success.
de Reuver PR, Rauws EA, Vermeulen M, Dijkgraaf MG, Gouma DJ, Bruno MJ
Gut 2007 Nov;56(11):1599-605. Epub 2007 Jun 26 doi: 10.1136/gut.2007.123596. PMID: 17595232Free PMC Article

Therapy

Efficacy and safety of endoscopic retrograde cholangiopancreatography with endoscopic sphincterotomy and biliary stenting in post-operative bile leaks.
Çelik M, Yilmaz H, Kılıç MC, Soykan M, Akbudak İH, Ozban M, Yilmaz M
Ulus Travma Acil Cerrahi Derg 2023 Aug;29(8):904-908. doi: 10.14744/tjtes.2023.49963. PMID: 37563904Free PMC Article
Identification and management of subvesical bile duct leakage after laparoscopic cholecystectomy: A systematic review.
Carannante F, Mazzotta E, Miacci V, Bianco G, Mascianà G, D'Agostino F, Caricato M, Capolupo GT
Asian J Surg 2023 Oct;46(10):4161-4168. Epub 2023 Apr 29 doi: 10.1016/j.asjsur.2023.04.031. PMID: 37127504
Occlusion of the cystic duct with cyanoacrylate glue at laparoscopic subtotal fenestrating cholecystectomy for a difficult gallbladder.
Jenner DC, Klimovskij M, Nicholls M, Bates T
Acta Chir Belg 2022 Feb;122(1):23-28. Epub 2020 Nov 19 doi: 10.1080/00015458.2020.1846937. PMID: 33210557
The Effect of Preoperative Biliary Drainage with or without Pancreatic Stenting on Complications after Pancreatoduodenectomy: A Retrospective Cohort Study.
Chu J, He S, Ke Y, Liu X, Wang P, Zhang W, Qiu G, Wang C, Zhang J, Wang G
Biomed Res Int 2021;2021:5572395. Epub 2021 Apr 29 doi: 10.1155/2021/5572395. PMID: 33997014Free PMC Article
Same-admission versus interval cholecystectomy for mild gallstone pancreatitis (PONCHO): a multicentre randomised controlled trial.
da Costa DW, Bouwense SA, Schepers NJ, Besselink MG, van Santvoort HC, van Brunschot S, Bakker OJ, Bollen TL, Dejong CH, van Goor H, Boermeester MA, Bruno MJ, van Eijck CH, Timmer R, Weusten BL, Consten EC, Brink MA, Spanier BWM, Bilgen EJS, Nieuwenhuijs VB, Hofker HS, Rosman C, Voorburg AM, Bosscha K, van Duijvendijk P, Gerritsen JJ, Heisterkamp J, de Hingh IH, Witteman BJ, Kruyt PM, Scheepers JJ, Molenaar IQ, Schaapherder AF, Manusama ER, van der Waaij LA, van Unen J, Dijkgraaf MG, van Ramshorst B, Gooszen HG, Boerma D; Dutch Pancreatitis Study Group
Lancet 2015 Sep 26;386(10000):1261-1268. doi: 10.1016/S0140-6736(15)00274-3. PMID: 26460661

Prognosis

Endoscopic treatment of post-surgical bile duct injuries: long term outcome and predictors of success.
de Reuver PR, Rauws EA, Vermeulen M, Dijkgraaf MG, Gouma DJ, Bruno MJ
Gut 2007 Nov;56(11):1599-605. Epub 2007 Jun 26 doi: 10.1136/gut.2007.123596. PMID: 17595232Free PMC Article
Perioperative outcome of laparoscopic left lateral liver resection is improved by using staple line reinforcement technique: a case report.
Consten EC, Gagner M
J Gastrointest Surg 2005 Mar;9(3):360-4. doi: 10.1016/j.gassur.2004.07.016. PMID: 15749597
Bile duct leaks after laparoscopic cholecystectomy: value of contrast-enhanced MRCP.
Aduna M, Larena JA, Martín D, Martínez-Guereñu B, Aguirre I, Astigarraga E
Abdom Imaging 2005 Jul-Aug;30(4):480-7. doi: 10.1007/s00261-004-0276-2. PMID: 15688109
Treatment of bile duct lesions after laparoscopic cholecystectomy.
Bergman JJ, van den Brink GR, Rauws EA, de Wit L, Obertop H, Huibregtse K, Tytgat GN, Gouma DJ
Gut 1996 Jan;38(1):141-7. doi: 10.1136/gut.38.1.141. PMID: 8566842Free PMC Article

Clinical prediction guides

Efficacy and safety of endoscopic retrograde cholangiopancreatography with endoscopic sphincterotomy and biliary stenting in post-operative bile leaks.
Çelik M, Yilmaz H, Kılıç MC, Soykan M, Akbudak İH, Ozban M, Yilmaz M
Ulus Travma Acil Cerrahi Derg 2023 Aug;29(8):904-908. doi: 10.14744/tjtes.2023.49963. PMID: 37563904Free PMC Article
The Effect of Preoperative Biliary Drainage with or without Pancreatic Stenting on Complications after Pancreatoduodenectomy: A Retrospective Cohort Study.
Chu J, He S, Ke Y, Liu X, Wang P, Zhang W, Qiu G, Wang C, Zhang J, Wang G
Biomed Res Int 2021;2021:5572395. Epub 2021 Apr 29 doi: 10.1155/2021/5572395. PMID: 33997014Free PMC Article
Rubber transcystic drainage reduces the post-removal biliary complications in liver transplantation: a matched case-control study.
Panaro F, Glaise A, Miggino M, Bouyabrine H, Carabalona J, Gallix B, Navarro F
Langenbecks Arch Surg 2013 Jan;398(1):169-76. Epub 2012 Jun 21 doi: 10.1007/s00423-012-0970-4. PMID: 22718298
Endoscopic treatment of post-surgical bile duct injuries: long term outcome and predictors of success.
de Reuver PR, Rauws EA, Vermeulen M, Dijkgraaf MG, Gouma DJ, Bruno MJ
Gut 2007 Nov;56(11):1599-605. Epub 2007 Jun 26 doi: 10.1136/gut.2007.123596. PMID: 17595232Free PMC Article

Recent systematic reviews

Identification and management of subvesical bile duct leakage after laparoscopic cholecystectomy: A systematic review.
Carannante F, Mazzotta E, Miacci V, Bianco G, Mascianà G, D'Agostino F, Caricato M, Capolupo GT
Asian J Surg 2023 Oct;46(10):4161-4168. Epub 2023 Apr 29 doi: 10.1016/j.asjsur.2023.04.031. PMID: 37127504

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