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Intra-oral hyperpigmentation

MedGen UID:: 585590
•Concept ID:: C0399483
•: Finding

Synonym:	Hyperpigmentation of the oral mucosa
SNOMED CT:	Melanin pigmentation of oral mucosa (235038002); Hyperpigmentation of oral mucosa (235038002)

HPO:	HP:0010284

Definition

Increased pigmentation, either focal or generalized, of the mucosa of the mouth. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVIntra-oral hyperpigmentation

Abnormality of the face
- Abnormality of the mouth
  - Abnormal oral morphology
    - Abnormal oral cavity morphology
      - Abnormal oral mucosa morphology
        Abnormal pigmentation of the oral mucosa
        Intra-oral hyperpigmentation

Conditions with this feature

Mandibuloacral dysplasia progeroid syndrome

MedGen UID:: 1741713
•Concept ID:: C5436867
•: Disease or Syndrome

Mandibuloacral dysplasia progeroid syndrome (MDPS) is an autosomal recessive severe laminopathy-like disorder characterized by growth retardation, bone resorption, arterial calcification, renal glomerulosclerosis, and hypertension (Elouej et al., 2020).

See: Condition Record

Mandibuloacral dysplasia progeroid syndrome

Professional guidelines

PubMed

Leprosy and its dental management guidelines.

Dave B, Bedi R
Int Dent J 2013 Apr;63(2):65-71. Epub 2013 Feb 5 doi: 10.1111/idj.12008. PMID: 23550518 Free PMC Article

Recent clinical studies

Diagnosis

Leprosy and its dental management guidelines.

Dave B, Bedi R
Int Dent J 2013 Apr;63(2):65-71. Epub 2013 Feb 5 doi: 10.1111/idj.12008. PMID: 23550518 Free PMC Article

Minocycline-associated intra-oral soft-tissue pigmentation: clinicopathologic correlations and review.

LaPorta VN, Nikitakis NG, Sindler AJ, Reynolds MA
J Clin Periodontol 2005 Feb;32(2):119-22. doi: 10.1111/j.1600-051X.2005.00646.x. PMID: 15691339

Therapy

Minocycline-associated intra-oral soft-tissue pigmentation: clinicopathologic correlations and review.

LaPorta VN, Nikitakis NG, Sindler AJ, Reynolds MA
J Clin Periodontol 2005 Feb;32(2):119-22. doi: 10.1111/j.1600-051X.2005.00646.x. PMID: 15691339

Oral melanin pigmentation in smoked and smokeless tobacco users in India. Clinico-pathological study.

Sarswathi TR, Kumar SN, Kavitha KM
Indian J Dent Res 2003 Apr-Jun;14(2):101-6. PMID: 14705454

Clinical prediction guides

Intra-oral hypermelanosis in an HIV sero-positive patient--a case report.

Kumar SN, Sarswathi TR, Ranganathan K
Indian J Dent Res 2003 Apr-Jun;14(2):131-4. PMID: 14705459

Oral melanin pigmentation in smoked and smokeless tobacco users in India. Clinico-pathological study.

Sarswathi TR, Kumar SN, Kavitha KM
Indian J Dent Res 2003 Apr-Jun;14(2):101-6. PMID: 14705454

Supplemental Content

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Clinical resources

ClinicalTrials.gov

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See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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Reviews

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