U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ruptured aneurysm

MedGen UID:
58001
•Concept ID:
C0162869
•
Disease or Syndrome
Synonyms: Aneurysm, Ruptured; Aneurysms, Ruptured; Ruptured Aneurysm; Ruptured Aneurysms
SNOMED CT: Ruptured aneurysm (22039006)

Definition

An aneurysm that has burst, resulting in hemorrhage into adjacent tissues. [from NCI]

Professional guidelines

PubMed

Contemporary management of aneurysmal subarachnoid haemorrhage. An update for the intensivist.
Robba C, Busl KM, Claassen J, Diringer MN, Helbok R, Park S, Rabinstein A, Treggiari M, Vergouwen MDI, Citerio G
Intensive Care Med 2024 May;50(5):646-664. Epub 2024 Apr 10 doi: 10.1007/s00134-024-07387-7. PMID: 38598130Free PMC Article
Approach to the Diagnosis and Management of Subarachnoid Hemorrhage.
Marcolini E, Hine J
West J Emerg Med 2019 Mar;20(2):203-211. Epub 2019 Feb 28 doi: 10.5811/westjem.2019.1.37352. PMID: 30881537Free PMC Article
The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm.
Chaikof EL, Dalman RL, Eskandari MK, Jackson BM, Lee WA, Mansour MA, Mastracci TM, Mell M, Murad MH, Nguyen LL, Oderich GS, Patel MS, Schermerhorn ML, Starnes BW
J Vasc Surg 2018 Jan;67(1):2-77.e2. doi: 10.1016/j.jvs.2017.10.044. PMID: 29268916

Recent clinical studies

Etiology

Contemporary management of aneurysmal subarachnoid haemorrhage. An update for the intensivist.
Robba C, Busl KM, Claassen J, Diringer MN, Helbok R, Park S, Rabinstein A, Treggiari M, Vergouwen MDI, Citerio G
Intensive Care Med 2024 May;50(5):646-664. Epub 2024 Apr 10 doi: 10.1007/s00134-024-07387-7. PMID: 38598130Free PMC Article
Aneurysmal Subarachnoid Hemorrhage: the Last Decade.
Neifert SN, Chapman EK, Martini ML, Shuman WH, Schupper AJ, Oermann EK, Mocco J, Macdonald RL
Transl Stroke Res 2021 Jun;12(3):428-446. Epub 2020 Oct 19 doi: 10.1007/s12975-020-00867-0. PMID: 33078345
Aneurysm Formation, Growth, and Rupture: The Biology and Physics of Cerebral Aneurysms.
Texakalidis P, Sweid A, Mouchtouris N, Peterson EC, Sioka C, Rangel-Castilla L, Reavey-Cantwell J, Jabbour P
World Neurosurg 2019 Oct;130:277-284. Epub 2019 Jul 16 doi: 10.1016/j.wneu.2019.07.093. PMID: 31323409
Unruptured intracranial aneurysms: development, rupture and preventive management.
Etminan N, Rinkel GJ
Nat Rev Neurol 2016 Dec;12(12):699-713. Epub 2016 Nov 3 doi: 10.1038/nrneurol.2016.150. PMID: 27808265
Visceral artery aneurysms.
Gehlen JM, Heeren PA, Verhagen PF, Peppelenbosch AG
Vasc Endovascular Surg 2011 Nov;45(8):681-7. doi: 10.1177/1538574411418129. PMID: 22262112

Diagnosis

Contemporary management of aneurysmal subarachnoid haemorrhage. An update for the intensivist.
Robba C, Busl KM, Claassen J, Diringer MN, Helbok R, Park S, Rabinstein A, Treggiari M, Vergouwen MDI, Citerio G
Intensive Care Med 2024 May;50(5):646-664. Epub 2024 Apr 10 doi: 10.1007/s00134-024-07387-7. PMID: 38598130Free PMC Article
Ruptured submitral aneurysm.
Shukla V, Nath RK, Pandit N
Indian Heart J 2016 Sep;68 Suppl 2(Suppl 2):S175-S177. Epub 2016 Feb 28 doi: 10.1016/j.ihj.2015.07.005. PMID: 27751280Free PMC Article
Renal artery aneurysms.
González J, Esteban M, Andrés G, Linares E, Martínez-Salamanca JI
Curr Urol Rep 2014 Jan;15(1):376. doi: 10.1007/s11934-013-0376-z. PMID: 24363127
Hepatic aneurysm: a review.
Hulsberg P, Garza-Jordan Jde L, Jordan R, Matusz P, Tubbs RS, Loukas M
Am Surg 2011 May;77(5):586-91. PMID: 21679592
Subarachnoid haemorrhage.
Al-Shahi R, White PM, Davenport RJ, Lindsay KW
BMJ 2006 Jul 29;333(7561):235-40. doi: 10.1136/bmj.333.7561.235. PMID: 16873858Free PMC Article

Therapy

Ultra-early tranexamic acid after subarachnoid haemorrhage (ULTRA): a randomised controlled trial.
Post R, Germans MR, Tjerkstra MA, Vergouwen MDI, Jellema K, Koot RW, Kruyt ND, Willems PWA, Wolfs JFC, de Beer FC, Kieft H, Nanda D, van der Pol B, Roks G, de Beer F, Halkes PHA, Reichman LJA, Brouwers PJAM, van den Berg-Vos RM, Kwa VIH, van der Ree TC, Bronner I, van de Vlekkert J, Bienfait HP, Boogaarts HD, Klijn CJM, van den Berg R, Coert BA, Horn J, Majoie CBLM, Rinkel GJE, Roos YBWEM, Vandertop WP, Verbaan D; ULTRA Investigators
Lancet 2021 Jan 9;397(10269):112-118. Epub 2020 Dec 23 doi: 10.1016/S0140-6736(20)32518-6. PMID: 33357465
Aneurysmal Subarachnoid Hemorrhage: the Last Decade.
Neifert SN, Chapman EK, Martini ML, Shuman WH, Schupper AJ, Oermann EK, Mocco J, Macdonald RL
Transl Stroke Res 2021 Jun;12(3):428-446. Epub 2020 Oct 19 doi: 10.1007/s12975-020-00867-0. PMID: 33078345
Subarachnoid Hemorrhage.
Lawton MT, Vates GE
N Engl J Med 2017 Jul 20;377(3):257-266. doi: 10.1056/NEJMcp1605827. PMID: 28723321
Aneurysmal Subarachnoid Hemorrhage.
D'Souza S
J Neurosurg Anesthesiol 2015 Jul;27(3):222-40. doi: 10.1097/ANA.0000000000000130. PMID: 25272066Free PMC Article
International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion.
Molyneux AJ, Kerr RS, Yu LM, Clarke M, Sneade M, Yarnold JA, Sandercock P; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group
Lancet 2005 Sep 3-9;366(9488):809-17. doi: 10.1016/S0140-6736(05)67214-5. PMID: 16139655

Prognosis

Sex differences in stroke.
Appelros P, Åsberg S
Handb Clin Neurol 2020;175:299-312. doi: 10.1016/B978-0-444-64123-6.00021-7. PMID: 33008533
European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage.
Steiner T, Juvela S, Unterberg A, Jung C, Forsting M, Rinkel G; European Stroke Organization
Cerebrovasc Dis 2013;35(2):93-112. Epub 2013 Feb 7 doi: 10.1159/000346087. PMID: 23406828
Visceral artery aneurysms.
Gehlen JM, Heeren PA, Verhagen PF, Peppelenbosch AG
Vasc Endovascular Surg 2011 Nov;45(8):681-7. doi: 10.1177/1538574411418129. PMID: 22262112
International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion.
Molyneux AJ, Kerr RS, Yu LM, Clarke M, Sneade M, Yarnold JA, Sandercock P; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group
Lancet 2005 Sep 3-9;366(9488):809-17. doi: 10.1016/S0140-6736(05)67214-5. PMID: 16139655
Carotid artery rupture.
Schiech L
Clin J Oncol Nurs 2000 Mar-Apr;4(2):93-4. PMID: 11107382

Clinical prediction guides

Advanced cross-sectional imaging of cerebral aneurysms.
Diab R, Chang D, Zhu C, Levitt MR, Aksakal M, Zhao HL, Huynh TJ, Romero-Sanchez G, Mossa-Basha M
Br J Radiol 2023 Jan 1;96(1141):20220686. Epub 2022 Dec 9 doi: 10.1259/bjr.20220686. PMID: 36400095Free PMC Article
Intracranial aneurysm wall (in)stability-current state of knowledge and clinical perspectives.
Morel S, Bijlenga P, Kwak BR
Neurosurg Rev 2022 Apr;45(2):1233-1253. Epub 2021 Nov 6 doi: 10.1007/s10143-021-01672-5. PMID: 34743248Free PMC Article
Cerebral Aneurysm Size before and after Rupture: Case Series and Literature Review.
Yi J, Zielinski D, Chen M
J Stroke Cerebrovasc Dis 2016 May;25(5):1244-1248. Epub 2016 Feb 27 doi: 10.1016/j.jstrokecerebrovasdis.2016.01.031. PMID: 26935121
Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies.
Greving JP, Wermer MJ, Brown RD Jr, Morita A, Juvela S, Yonekura M, Ishibashi T, Torner JC, Nakayama T, Rinkel GJ, Algra A
Lancet Neurol 2014 Jan;13(1):59-66. Epub 2013 Nov 27 doi: 10.1016/S1474-4422(13)70263-1. PMID: 24290159
European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage.
Steiner T, Juvela S, Unterberg A, Jung C, Forsting M, Rinkel G; European Stroke Organization
Cerebrovasc Dis 2013;35(2):93-112. Epub 2013 Feb 7 doi: 10.1159/000346087. PMID: 23406828

Recent systematic reviews

Splenic artery aneurysm in pregnancy: A systematic review.
Aung YY, Berry C, Jayaram PR, Woon EV
Int J Gynaecol Obstet 2023 Jan;160(1):1-11. Epub 2022 Jun 14 doi: 10.1002/ijgo.14278. PMID: 35598155
Acute abdominal pain in older adults: a clinical and diagnostic challenge.
Sangiorgio G, Biondi A, Basile F, Vacante M
Minerva Chir 2020 Jun;75(3):169-172. doi: 10.23736/S0026-4733.20.08266-8. PMID: 32550726
Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the Population: A Systematic Review and Meta-analysis.
Etminan N, Chang HS, Hackenberg K, de Rooij NK, Vergouwen MDI, Rinkel GJE, Algra A
JAMA Neurol 2019 May 1;76(5):588-597. doi: 10.1001/jamaneurol.2019.0006. PMID: 30659573Free PMC Article
Hemodynamic Stress, Inflammation, and Intracranial Aneurysm Development and Rupture: A Systematic Review.
Signorelli F, Sela S, Gesualdo L, Chevrel S, Tollet F, Pailler-Mattei C, Tacconi L, Turjman F, Vacca A, Schul DB
World Neurosurg 2018 Jul;115:234-244. Epub 2018 Apr 27 doi: 10.1016/j.wneu.2018.04.143. PMID: 29709752
Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies.
Greving JP, Wermer MJ, Brown RD Jr, Morita A, Juvela S, Yonekura M, Ishibashi T, Torner JC, Nakayama T, Rinkel GJ, Algra A
Lancet Neurol 2014 Jan;13(1):59-66. Epub 2013 Nov 27 doi: 10.1016/S1474-4422(13)70263-1. PMID: 24290159

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...