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Discoloration of skin

MedGen UID:
57741
•Concept ID:
C0151907
•
Finding
Synonyms: Dyschromia; Skin Discoloration; Skin Dyschromia
SNOMED CT: Dyschromia (3253007); Discoloration of skin (3253007)

Definition

Abnormal skin coloration. [from NCI]

Professional guidelines

PubMed

Evaluation of the effects of carboxytherapy in the treatment of periorbital dark circles.
Tabaie SM, Shirkavand A, Mansouri P, Mehrizi AAH, Farshi S
J Cosmet Dermatol 2024 Aug;23(8):2711-2715. Epub 2024 Jun 3 doi: 10.1111/jocd.16331. PMID: 38831554
Estimation of the utilities of attributes of intravenous iron infusion treatment for patients with iron-deficiency anemia: a conjoint analysis in Japan.
Takeshima T, Ha C, Iwasaki K
J Med Econ 2023 Jan-Dec;26(1):84-94. doi: 10.1080/13696998.2022.2158661. PMID: 36519281
Light and laser therapies for the treatment of sebaceous gland hyperplasia a review of the literature.
Simmons BJ, Griffith RD, Falto-Aizpurua LA, Bray FN, Nouri K; International League of Dermatological Societies; European Dermatology Forum
J Eur Acad Dermatol Venereol 2015 Nov;29(11):2080-7. Epub 2015 Mar 2 doi: 10.1111/jdv.13066. PMID: 25731611

Recent clinical studies

Etiology

Amiodarone Related Skin Toxicity -The Blue Man Syndrome; a Case Report and Review of Literature.
Safdar A, Ahmed T, Fatima S, Nasser MM
Curr Probl Cardiol 2022 Nov;47(11):101315. Epub 2022 Jul 8 doi: 10.1016/j.cpcardiol.2022.101315. PMID: 35817158
Safety of retigabine in adults with partial-onset seizures after long-term exposure: focus on unexpected ophthalmological and dermatological events.
Brickel N, Hewett K, Rayner K, McDonald S, De'Ath J, Daniluk J, Joshi K, Boll MC, Tiamkao S, Vorobyeva O, Cooper J
Epilepsy Behav 2020 Jan;102:106580. Epub 2019 Nov 12 doi: 10.1016/j.yebeh.2019.106580. PMID: 31731109
Cervical Lipomyelocele with Congenital Inclusion Cyst.
Kaur M, Aggarwal A, Sharma A, Malik A
World Neurosurg 2019 Oct;130:122-128. Epub 2019 Jun 28 doi: 10.1016/j.wneu.2019.06.179. PMID: 31255725
Analysis of Manganese Superoxide Dismutase and Glutathione Peroxidase 1 Gene Polymorphisms in Vitiligo.
Seçkin HY, Kalkan G, Bütün İ, Akbaş A, Baş Y, Karakuş N, Benli İ
Biochem Genet 2016 Aug;54(4):438-447. Epub 2016 Apr 21 doi: 10.1007/s10528-016-9730-4. PMID: 27100222
Cutaneous side effects associated with sunitinib: an analysis of 8 cases.
Vignand-Courtin C, Martin C, Le Beller C, Mateus C, Barbault-Foucher S, Rieutord A
Int J Clin Pharm 2012 Apr;34(2):286-9. Epub 2012 Mar 17 doi: 10.1007/s11096-012-9615-5. PMID: 22427001

Diagnosis

Design and Characterization of Nanoflowers-based Biosensor for Estimation of Bilirubin in Jaundice.
Acharya K, Prabhakar B, Shende P
Yale J Biol Med 2023 Mar;96(1):3-12. Epub 2023 Mar 31 doi: 10.59249/TJIV3644. PMID: 37009196Free PMC Article
Amiodarone Related Skin Toxicity -The Blue Man Syndrome; a Case Report and Review of Literature.
Safdar A, Ahmed T, Fatima S, Nasser MM
Curr Probl Cardiol 2022 Nov;47(11):101315. Epub 2022 Jul 8 doi: 10.1016/j.cpcardiol.2022.101315. PMID: 35817158
Safety of retigabine in adults with partial-onset seizures after long-term exposure: focus on unexpected ophthalmological and dermatological events.
Brickel N, Hewett K, Rayner K, McDonald S, De'Ath J, Daniluk J, Joshi K, Boll MC, Tiamkao S, Vorobyeva O, Cooper J
Epilepsy Behav 2020 Jan;102:106580. Epub 2019 Nov 12 doi: 10.1016/j.yebeh.2019.106580. PMID: 31731109
Orbital intramuscular haemangioma.
Christensen SR, Børgesen SE, Heegaard S, Prause JU
Acta Ophthalmol Scand 2002 Jun;80(3):336-9. doi: 10.1034/j.1600-0420.2002.800320.x. PMID: 12059877
Carbon monoxide poisoning.
Mehta SR, Niyogi M, Kasthuri AS, Dubal U, Bindra S, Prasad D, Lahiri AK
J Assoc Physicians India 2001 Jun;49:622-5. PMID: 11584937

Therapy

Amiodarone Related Skin Toxicity -The Blue Man Syndrome; a Case Report and Review of Literature.
Safdar A, Ahmed T, Fatima S, Nasser MM
Curr Probl Cardiol 2022 Nov;47(11):101315. Epub 2022 Jul 8 doi: 10.1016/j.cpcardiol.2022.101315. PMID: 35817158
Safety of retigabine in adults with partial-onset seizures after long-term exposure: focus on unexpected ophthalmological and dermatological events.
Brickel N, Hewett K, Rayner K, McDonald S, De'Ath J, Daniluk J, Joshi K, Boll MC, Tiamkao S, Vorobyeva O, Cooper J
Epilepsy Behav 2020 Jan;102:106580. Epub 2019 Nov 12 doi: 10.1016/j.yebeh.2019.106580. PMID: 31731109
Black bone disease of the foot: a case study and review of literature demonstrating a correlation of long-term minocycline therapy and bone hyperpigmentation.
Kerbleski GJ, Hampton TT, Cornejo A
J Foot Ankle Surg 2013 Mar-Apr;52(2):239-41. Epub 2013 Jan 9 doi: 10.1053/j.jfas.2012.10.018. PMID: 23312403
Cutaneous side effects associated with sunitinib: an analysis of 8 cases.
Vignand-Courtin C, Martin C, Le Beller C, Mateus C, Barbault-Foucher S, Rieutord A
Int J Clin Pharm 2012 Apr;34(2):286-9. Epub 2012 Mar 17 doi: 10.1007/s11096-012-9615-5. PMID: 22427001
Melanin and facial skin fluorescence as markers of yellowish discoloration with aging.
Ohshima H, Oyobikawa M, Tada A, Maeda T, Takiwaki H, Itoh M, Kanto H
Skin Res Technol 2009 Nov;15(4):496-502. doi: 10.1111/j.1600-0846.2009.00396.x. PMID: 19832964

Prognosis

Amiodarone Related Skin Toxicity -The Blue Man Syndrome; a Case Report and Review of Literature.
Safdar A, Ahmed T, Fatima S, Nasser MM
Curr Probl Cardiol 2022 Nov;47(11):101315. Epub 2022 Jul 8 doi: 10.1016/j.cpcardiol.2022.101315. PMID: 35817158
Safety of retigabine in adults with partial-onset seizures after long-term exposure: focus on unexpected ophthalmological and dermatological events.
Brickel N, Hewett K, Rayner K, McDonald S, De'Ath J, Daniluk J, Joshi K, Boll MC, Tiamkao S, Vorobyeva O, Cooper J
Epilepsy Behav 2020 Jan;102:106580. Epub 2019 Nov 12 doi: 10.1016/j.yebeh.2019.106580. PMID: 31731109
Cutaneous side effects associated with sunitinib: an analysis of 8 cases.
Vignand-Courtin C, Martin C, Le Beller C, Mateus C, Barbault-Foucher S, Rieutord A
Int J Clin Pharm 2012 Apr;34(2):286-9. Epub 2012 Mar 17 doi: 10.1007/s11096-012-9615-5. PMID: 22427001
Nicolau syndrome following intramuscular benzathine penicillin.
De Sousa R, Dang A, Rataboli PV
J Postgrad Med 2008 Oct-Dec;54(4):332-4. doi: 10.4103/0022-3859.43523. PMID: 18953160
Epidemiological study of measles in slum areas of Kolkata.
Ray SK, Mallik S, Munsi AK, Mitra SP, Baur B, Kumar S
Indian J Pediatr 2004 Jul;71(7):583-6. doi: 10.1007/BF02724116. PMID: 15280606

Clinical prediction guides

Pulmonary toxicity of silver vapours, nanoparticles and fine dusts: A review.
Hadrup N, Sharma AK, Loeschner K, Jacobsen NR
Regul Toxicol Pharmacol 2020 Aug;115:104690. Epub 2020 May 28 doi: 10.1016/j.yrtph.2020.104690. PMID: 32474071
Pre-clinical toxicity evaluation of MB-102, a novel fluorescent tracer agent for real-time measurement of glomerular filtration rate.
Bugaj JE, Dorshow RB
Regul Toxicol Pharmacol 2015 Jun;72(1):26-38. Epub 2015 Feb 26 doi: 10.1016/j.yrtph.2015.02.018. PMID: 25728979
Cutaneous side effects associated with sunitinib: an analysis of 8 cases.
Vignand-Courtin C, Martin C, Le Beller C, Mateus C, Barbault-Foucher S, Rieutord A
Int J Clin Pharm 2012 Apr;34(2):286-9. Epub 2012 Mar 17 doi: 10.1007/s11096-012-9615-5. PMID: 22427001
Melanin and facial skin fluorescence as markers of yellowish discoloration with aging.
Ohshima H, Oyobikawa M, Tada A, Maeda T, Takiwaki H, Itoh M, Kanto H
Skin Res Technol 2009 Nov;15(4):496-502. doi: 10.1111/j.1600-0846.2009.00396.x. PMID: 19832964
Orbital intramuscular haemangioma.
Christensen SR, Børgesen SE, Heegaard S, Prause JU
Acta Ophthalmol Scand 2002 Jun;80(3):336-9. doi: 10.1034/j.1600-0420.2002.800320.x. PMID: 12059877

Supplemental Content

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